{"id":"https://openalex.org/W2124267461","doi":"https://doi.org/10.1086/314658","title":"No Evidence for an Effect of the CCR5 \u039432/+ and CCR2b 64I/+ Mutations on Human Immunodeficiency Virus (HIV)\u20101 Disease Progression among HIV\u20101\u2013Infected Injecting Drug Users","display_name":"No Evidence for an Effect of the CCR5 \u039432/+ and CCR2b 64I/+ Mutations on Human Immunodeficiency Virus (HIV)\u20101 Disease Progression among HIV\u20101\u2013Infected Injecting Drug Users","publication_year":1999,"publication_date":"1999-04-01","ids":{"openalex":"https://openalex.org/W2124267461","doi":"https://doi.org/10.1086/314658","mag":"2124267461","pmid":"https://pubmed.ncbi.nlm.nih.gov/10068577"},"language":"en","primary_location":{"id":"doi:10.1086/314658","doi":"https://doi.org/10.1086/314658","is_oa":true,"landing_page_url":"https://doi.org/10.1086/314658","pdf_url":"https://academic.oup.com/jid/article-pdf/179/4/825/17991628/179-4-825.pdf","source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jid/article-pdf/179/4/825/17991628/179-4-825.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062827814","display_name":"Janke Schinkel","orcid":"https://orcid.org/0000-0002-1112-0644","observed_orcids":["https://orcid.org/0000-0002-1112-0644"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Janke Schinkel","raw_affiliation_strings":["Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam, The Netherlands","Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam, The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059454433","display_name":"Miranda W. Langendam","orcid":"https://orcid.org/0000-0001-9038-3209","observed_orcids":["https://orcid.org/0000-0001-9038-3209"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Miranda\u00a0W. Langendam","raw_affiliation_strings":["Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111927182","display_name":"Roel A. Coutinho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Roel\u00a0A. Coutinho","raw_affiliation_strings":["Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109088200","display_name":"Anneke Krol","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Anneke Krol","raw_affiliation_strings":["Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021036148","display_name":"Margreet Brouwer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Margreet Brouwer","raw_affiliation_strings":["Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014967648","display_name":"Hanneke Schuitemaker","orcid":"https://orcid.org/0000-0001-8563-2266","observed_orcids":["https://orcid.org/0000-0001-8563-2266"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Hanneke Schuitemaker","raw_affiliation_strings":["Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Municipal Health Service, Division of Public Health and Environment, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Department of Clinical Viro-immunology, and Academic Medical Center, Department of Human Retrovirology, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014967648"],"corresponding_institution_ids":["https://openalex.org/I2802928900"],"apc_list":{"value":4763,"currency":"USD","value_usd":4763},"apc_paid":null,"fwci":2.0267,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.86509827,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"179","issue":"4","first_page":"825","last_page":"831"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ccr5-delta32-mutation","display_name":"CCR5 delta32 mutation","score":0.7580000162124634},{"id":"https://openalex.org/keywords/hiv-1-disease-progression","display_name":"HIV-1 disease progression","score":0.9760000109672546},{"id":"https://openalex.org/keywords/people-who-inject-drugs","display_name":"people who inject drugs","score":0.9679999947547913},{"id":"https://openalex.org/keywords/seroconversion","display_name":"seroconversion","score":0.7269999980926514},{"id":"https://openalex.org/keywords/cd4-count-decline","display_name":"CD4 count decline","score":0.906000018119812},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.9800000190734863},{"id":"https://openalex.org/keywords/aids","display_name":"AIDS","score":0.4699999988079071},{"id":"https://openalex.org/keywords/ccr5-coreceptor","display_name":"CCR5 coreceptor","score":0.4869999885559082},{"id":"https://openalex.org/keywords/ccr2","display_name":"CCR2","score":0.7670000195503235},{"id":"https://openalex.org/keywords/hiv-transmission-routes","display_name":"HIV transmission routes","score":0.5630000233650208},{"id":"https://openalex.org/keywords/hiv-1-variants","display_name":"HIV-1 variants","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C2777451964","wikidata":"https://www.wikidata.org/wiki/Q2141450","display_name":"Seroconversion","level":3,"score":0.7251712083816528},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5773199200630188},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.5649631023406982},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5546888113021851},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5532023906707764},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4913918077945709},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.48111671209335327},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4767371416091919},{"id":"https://openalex.org/C2776452011","wikidata":"https://www.wikidata.org/wiki/Q311463","display_name":"Sida","level":4,"score":0.4654223620891571},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.4357723295688629},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.4185560345649719},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34127330780029297},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2449188232421875},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12658312916755676},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11209440231323242}],"mesh":[{"descriptor_ui":"D000163","descriptor_name":"Acquired Immunodeficiency Syndrome","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014766","descriptor_name":"Viremia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015819","descriptor_name":"Substance Abuse, Intravenous","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018791","descriptor_name":"CD4 Lymphocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019707","descriptor_name":"Receptors, Chemokine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019713","descriptor_name":"Receptors, CCR5","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D054390","descriptor_name":"Receptors, CCR2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":11,"locations":[{"id":"doi:10.1086/314658","doi":"https://doi.org/10.1086/314658","is_oa":true,"landing_page_url":"https://doi.org/10.1086/314658","pdf_url":"https://academic.oup.com/jid/article-pdf/179/4/825/17991628/179-4-825.pdf","source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:10068577","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10068577","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of infectious diseases","raw_type":"Journal Article"},{"id":"pmh:oai:dare.uva.nl:openaire/760cc47f-1895-4f71-8931-1871ed4c5de2","doi":null,"is_oa":true,"landing_page_url":"https://handle.uba.uva.nl/personal/pure/en/publications/no-evidence-for-an-effect-of-the-ccr5-32-and-ccr2b-64i-mutations-on-human-immunodeficiency-virus-hiv1-disease-progression-among-hiv1infected-injecting-drug-users(760cc47f-1895-4f71-8931-1871ed4c5de2).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400088","display_name":"UvA-DARE (University of Amsterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I887064364","host_organization_name":"University of Amsterdam","host_organization_lineage":["https://openalex.org/I887064364"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schinkel, J, Langendam, M W, Coutinho, R A, Krol, A, Brouwer, M & Schuitemaker, H 1999, 'No evidence for an effect of the CCR5 \u039432/+ and CCR2b 64I/+ mutations on human immunodeficiency virus (HIV)-1 disease progression among HIV-1-infected injecting drug users', The Journal of Infectious Diseases, vol. 179, no. 4, pp. 825-831. https://doi.org/10.1086/314658","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.602.2348","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.602.2348","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.amsterdamcohortstudies.org/data/99169172/fulltext99169172.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.935.6810","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.935.6810","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jid.oxfordjournals.org/content/179/4/825.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.942.8736","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.942.8736","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dare.uva.nl/document/2/6191/","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.953.4306","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.953.4306","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dare.uva.nl/document/2/42838/","raw_type":"text"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/feda2190-ba4e-42cd-a8c6-0aae5793465a","doi":null,"is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/no-evidence-for-an-effect-of-the-ccr5-delta32-and-ccr2b-64i-mutations-on-human-immunodeficiency-virus-hiv1-disease-progression-among-hiv1infected-injecting-drug-users(feda2190-ba4e-42cd-a8c6-0aae5793465a).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of infectious diseases, 179(4), 825 - 831. Oxford University Press","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/baf8da41-b8d6-4a4c-a2b4-75265d2c9600","doi":null,"is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/baf8da41-b8d6-4a4c-a2b4-75265d2c9600","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Schinkel, J, Langendam, M W, Coutinho, R A, Krol, A, Brouwer, M & Schuitemaker, H 1999, 'No evidence for an effect of the CCR5 delta32/+ and CCR2b 64I/+ mutations on human immunodeficiency virus (HIV)-1 disease progression among HIV-1-infected injecting drug users', Journal of infectious diseases, vol. 179, no. 4, pp. 825-831. https://doi.org/10.1086/314658","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:uvapub:oai:dare.uva.nl:publications/01acee78-0df4-49ce-bc46-e262986ac512","doi":null,"is_oa":true,"landing_page_url":"https://dare.uva.nl/personal/pure/en/publications/no-evidence-for-an-effect-of-the-ccr5-delta32-and-ccr2b-64i-mutations-on-human-immunodeficiency-virus-hiv1-disease-progression-among-hiv1infected-injecting-drug-users(01acee78-0df4-49ce-bc46-e262986ac512).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Journal of Infectious Diseases, 179, 825 - 831. Oxford University Press","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:uvapub:oai:dare.uva.nl:publications/760cc47f-1895-4f71-8931-1871ed4c5de2","doi":null,"is_oa":true,"landing_page_url":"https://dare.uva.nl/personal/pure/en/publications/no-evidence-for-an-effect-of-the-ccr5-delta32-and-ccr2b-64i-mutations-on-human-immunodeficiency-virus-hiv1-disease-progression-among-hiv1infected-injecting-drug-users(760cc47f-1895-4f71-8931-1871ed4c5de2).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Journal of Infectious Diseases, 179, 825 - 831. Oxford University Press","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1086/314658","doi":"https://doi.org/10.1086/314658","is_oa":true,"landing_page_url":"https://doi.org/10.1086/314658","pdf_url":"https://academic.oup.com/jid/article-pdf/179/4/825/17991628/179-4-825.pdf","source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2124267461.pdf","grobid_xml":"https://content.openalex.org/works/W2124267461.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W82820957","https://openalex.org/W1550022419","https://openalex.org/W1551243371","https://openalex.org/W1593164578","https://openalex.org/W1981440980","https://openalex.org/W1981644527","https://openalex.org/W1983186928","https://openalex.org/W1984811742","https://openalex.org/W1986396274","https://openalex.org/W1986574361","https://openalex.org/W1989701896","https://openalex.org/W1991027199","https://openalex.org/W2007021820","https://openalex.org/W2020947821","https://openalex.org/W2021932640","https://openalex.org/W2026444780","https://openalex.org/W2041295679","https://openalex.org/W2061489657","https://openalex.org/W2063023106","https://openalex.org/W2073608015","https://openalex.org/W2076210505","https://openalex.org/W2083131690","https://openalex.org/W2090630729","https://openalex.org/W2096635934","https://openalex.org/W2112517802","https://openalex.org/W2119904919","https://openalex.org/W2126597682","https://openalex.org/W2131376910","https://openalex.org/W2133021844","https://openalex.org/W2149730509","https://openalex.org/W2158294445","https://openalex.org/W2168353302","https://openalex.org/W2320697799","https://openalex.org/W2325226062","https://openalex.org/W3140059998","https://openalex.org/W6665576621"],"related_works":["https://openalex.org/W7098162401","https://openalex.org/W7095323297","https://openalex.org/W7097196872","https://openalex.org/W1551243371","https://openalex.org/W2115226150","https://openalex.org/W2149730509","https://openalex.org/W2415068905","https://openalex.org/W2112056977","https://openalex.org/W2099283936","https://openalex.org/W3013208404"],"abstract_inverted_index":{"The":[0],"relationship":[1],"between":[2,96,124],"CCR5":[3,44,98,118],"and":[4,7,46,83,99,103,119,126],"CCR2b":[5,48,100,120],"genotypes":[6,50],"human":[8],"immunodeficiency":[9],"virus":[10,84],"(HIV)-1":[11],"disease":[12,40],"progression":[13,41,54],"was":[14,51,64],"studied":[15],"among":[16,34],"the":[17,21,43,47,87,97,117,132,145],"108":[18],"seroconverters":[19],"of":[20,24,42,116,135,144],"Amsterdam":[22],"cohort":[23],"injecting":[25],"drug":[26],"users":[27],"(IDUs).":[28],"In":[29],"contrast":[30],"to":[31,55],"earlier":[32],"studies":[33],"homosexual":[35,127],"men,":[36],"no":[37,113],"effect":[38,115],"on":[39],"Delta32/+":[45],"64I/+":[49],"found,":[52],"when":[53],"AIDS,":[56],"death,":[57],"or":[58,142],"a":[59,67,77],"CD4":[60,73],"cell":[61,74],"count":[62],"<200/microL":[63],"compared":[65],"by":[66],"Cox":[68],"proportional":[69],"hazards":[70],"model.":[71],"Furthermore,":[72],"decline":[75],"(by":[76],"regression":[78],"model":[79],"for":[80,131],"repeated":[81],"measurements)":[82],"load":[85],"in":[86,139,150],"first":[88],"3":[89],"years":[90],"after":[91],"seroconversion":[92],"did":[93],"not":[94],"differ":[95],"wild":[101],"type":[102],"heterozygous":[104],"genotypes.":[105],"A":[106],"nested":[107],"matched":[108],"case-control":[109],"study":[110],"also":[111,153],"revealed":[112],"significant":[114],"mutations.":[121],"Immunologic":[122],"differences":[123],"IDUs":[125,151],"men":[128],"may":[129],"account":[130],"observed":[133],"lack":[134],"effect.":[136],"Alternatively,":[137],"difference":[138],"transmission":[140],"route":[141],"characteristics":[143],"HIV-1":[146],"variants":[147],"that":[148],"circulate":[149],"could":[152],"explain":[154],"this":[155],"phenomenon.":[156]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}