{"id":"https://openalex.org/W2124187564","doi":null,"title":"IDENTIFICATION AND CHARACTERIZATION OF WASP AND FKBP-LIKE PROTEIN","display_name":"IDENTIFICATION AND CHARACTERIZATION OF WASP AND FKBP-LIKE PROTEIN","publication_year":2009,"publication_date":"2009-02-20","ids":{"openalex":"https://openalex.org/W2124187564","mag":"2124187564"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26903224","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Identification_and_characterization_of_WASP_and_FKBP-like_protein/26903224","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/39194","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072048895","display_name":"Ing-Marie Viklund","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ing-Marie Viklund","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5072048895"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wiskott-aldrich-syndrome","display_name":"Wiskott-Aldrich syndrome","score":0.7149999737739563},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.8809999823570251},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.9649999737739563},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.9670000076293945},{"id":"https://openalex.org/keywords/early-endosomes","display_name":"early endosomes","score":0.7300000190734863},{"id":"https://openalex.org/keywords/phosphatidylinositol-3-phosphate","display_name":"phosphatidylinositol 3-phosphate","score":0.7540000081062317},{"id":"https://openalex.org/keywords/actin-based-transport","display_name":"actin-based transport","score":0.6650000214576721},{"id":"https://openalex.org/keywords/wasp-interacting-protein","display_name":"WASP-interacting protein","score":0.7799999713897705},{"id":"https://openalex.org/keywords/membrane-trafficking","display_name":"membrane trafficking","score":0.6029999852180481},{"id":"https://openalex.org/keywords/colonic-mucosa","display_name":"colonic mucosa","score":0.6779999732971191},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.6660000085830688},{"id":"https://openalex.org/keywords/phagosome","display_name":"phagosome","score":0.593999981880188},{"id":"https://openalex.org/keywords/salmonella","display_name":"Salmonella","score":0.7009999752044678},{"id":"https://openalex.org/keywords/salmonella-enterica-serovar-typhi","display_name":"Salmonella typhi","score":0.46700000762939453}],"concepts":[{"id":"https://openalex.org/C196436469","wikidata":"https://www.wikidata.org/wiki/Q6587700","display_name":"Suppression subtractive hybridization","level":5,"score":0.8103083372116089},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6481925845146179},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.613551139831543},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.5936251282691956},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.5438152551651001},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5214109420776367},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49714305996894836},{"id":"https://openalex.org/C2775862500","wikidata":"https://www.wikidata.org/wiki/Q2453464","display_name":"Colitis","level":2,"score":0.462146133184433},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.42778024077415466},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.42642468214035034},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.36013561487197876},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3232995867729187},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2463040053844452},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19870221614837646},{"id":"https://openalex.org/C189482833","wikidata":"https://www.wikidata.org/wiki/Q869146","display_name":"cDNA library","level":4,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26903224","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Identification_and_characterization_of_WASP_and_FKBP-like_protein/26903224","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/39194","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/39194","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2124187564","doi":null,"is_oa":false,"landing_page_url":"https://openarchive.ki.se/xmlui/bitstream/handle/10616/39194/thesis.pdf;sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/39194","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/39194","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":292,"referenced_works":["https://openalex.org/W21408002","https://openalex.org/W24453619","https://openalex.org/W27136445","https://openalex.org/W73143332","https://openalex.org/W259603363","https://openalex.org/W583414473","https://openalex.org/W1484794460","https://openalex.org/W1509485250","https://openalex.org/W1524475817","https://openalex.org/W1525528026","https://openalex.org/W1526083898","https://openalex.org/W1562818166","https://openalex.org/W1565504254","https://openalex.org/W1570678799","https://openalex.org/W1575892864","https://openalex.org/W1575962411","https://openalex.org/W1587128314","https://openalex.org/W1595083713","https://openalex.org/W1595181072","https://openalex.org/W1595436183","https://openalex.org/W1603724904","https://openalex.org/W1614056212","https://openalex.org/W1642457845","https://openalex.org/W1670573097","https://openalex.org/W1715906171","https://openalex.org/W1822252127","https://openalex.org/W1902457626","https://openalex.org/W1964922201","https://openalex.org/W1965404941","https://openalex.org/W1966926645","https://openalex.org/W1967265946","https://openalex.org/W1967289387","https://openalex.org/W1967391569","https://openalex.org/W1969117282","https://openalex.org/W1969393298","https://openalex.org/W1970046422","https://openalex.org/W1970756887","https://openalex.org/W1974277649","https://openalex.org/W1974955986","https://openalex.org/W1975300355","https://openalex.org/W1977100348","https://openalex.org/W1978833026","https://openalex.org/W1979859398","https://openalex.org/W1980431822","https://openalex.org/W1980911614","https://openalex.org/W1981407991","https://openalex.org/W1981714996","https://openalex.org/W1981747825","https://openalex.org/W1982074683","https://openalex.org/W1982745561","https://openalex.org/W1983992348","https://openalex.org/W1984879151","https://openalex.org/W1985936786","https://openalex.org/W1986978360","https://openalex.org/W1987958246","https://openalex.org/W1988468504","https://openalex.org/W1989506542","https://openalex.org/W1989630349","https://openalex.org/W1989642116","https://openalex.org/W1989686043","https://openalex.org/W1989875198","https://openalex.org/W1989950081","https://openalex.org/W1990741894","https://openalex.org/W1991311491","https://openalex.org/W1991691364","https://openalex.org/W1991723267","https://openalex.org/W1992484552","https://openalex.org/W1995336211","https://openalex.org/W1998975377","https://openalex.org/W1999388825","https://openalex.org/W1999477899","https://openalex.org/W2000106054","https://openalex.org/W2000302106","https://openalex.org/W2000934898","https://openalex.org/W2000994188","https://openalex.org/W2001532503","https://openalex.org/W2003438735","https://openalex.org/W2003603726","https://openalex.org/W2005209191","https://openalex.org/W2005574904","https://openalex.org/W2006585409","https://openalex.org/W2006996074","https://openalex.org/W2007230636","https://openalex.org/W2007586038","https://openalex.org/W2007797957","https://openalex.org/W2007942193","https://openalex.org/W2008117836","https://openalex.org/W2009706335","https://openalex.org/W2011197968","https://openalex.org/W2011325978","https://openalex.org/W2012107438","https://openalex.org/W2012188138","https://openalex.org/W2012652689","https://openalex.org/W2013454744","https://openalex.org/W2014304617","https://openalex.org/W2016253390","https://openalex.org/W2017443683","https://openalex.org/W2017593971","https://openalex.org/W2019196882","https://openalex.org/W2021303199","https://openalex.org/W2021329171","https://openalex.org/W2022762256","https://openalex.org/W2023712216","https://openalex.org/W2024316397","https://openalex.org/W2025566577","https://openalex.org/W2025615154","https://openalex.org/W2025722012","https://openalex.org/W2027775552","https://openalex.org/W2027810531","https://openalex.org/W2028863272","https://openalex.org/W2029022457","https://openalex.org/W2031035500","https://openalex.org/W2031123547","https://openalex.org/W2031183440","https://openalex.org/W2033619721","https://openalex.org/W2034748491","https://openalex.org/W2036780034","https://openalex.org/W2038760621","https://openalex.org/W2038876182","https://openalex.org/W2039799445","https://openalex.org/W2040548821","https://openalex.org/W2041112864","https://openalex.org/W2042212641","https://openalex.org/W2042324409","https://openalex.org/W2043646282","https://openalex.org/W2044084413","https://openalex.org/W2045923054","https://openalex.org/W2046482455","https://openalex.org/W2046579578","https://openalex.org/W2046642934","https://openalex.org/W2047434131","https://openalex.org/W2047579047","https://openalex.org/W2047920353","https://openalex.org/W2049791243","https://openalex.org/W2049811440","https://openalex.org/W2052875965","https://openalex.org/W2053031822","https://openalex.org/W2053527054","https://openalex.org/W2053789332","https://openalex.org/W2054385006","https://openalex.org/W2055188333","https://openalex.org/W2055521207","https://openalex.org/W2059015272","https://openalex.org/W2059076214","https://openalex.org/W2061791452","https://openalex.org/W2062371417","https://openalex.org/W2063263218","https://openalex.org/W2064619165","https://openalex.org/W2065260973","https://openalex.org/W2066296494","https://openalex.org/W2066558638","https://openalex.org/W2069732926","https://openalex.org/W2070015389","https://openalex.org/W2071631353","https://openalex.org/W2072508525","https://openalex.org/W2072837740","https://openalex.org/W2072936656","https://openalex.org/W2073005565","https://openalex.org/W2074057696","https://openalex.org/W2075188939","https://openalex.org/W2075846364","https://openalex.org/W2076261565","https://openalex.org/W2078313196","https://openalex.org/W2078384542","https://openalex.org/W2078530446","https://openalex.org/W2078621117","https://openalex.org/W2078668029","https://openalex.org/W2080195364","https://openalex.org/W2081389905","https://openalex.org/W2082315732","https://openalex.org/W2082543204","https://openalex.org/W2083087230","https://openalex.org/W2085022435","https://openalex.org/W2085313371","https://openalex.org/W2086053245","https://openalex.org/W2086199657","https://openalex.org/W2086607027","https://openalex.org/W2086698861","https://openalex.org/W2087266324","https://openalex.org/W2088195013","https://openalex.org/W2088686584","https://openalex.org/W2091238762","https://openalex.org/W2091323369","https://openalex.org/W2091707906","https://openalex.org/W2091884933","https://openalex.org/W2094464340","https://openalex.org/W2094625991","https://openalex.org/W2095039458","https://openalex.org/W2095393268","https://openalex.org/W2095798079","https://openalex.org/W2096063169","https://openalex.org/W2096613739","https://openalex.org/W2097177097","https://openalex.org/W2097554174","https://openalex.org/W2099573412","https://openalex.org/W2099662390","https://openalex.org/W2100443415","https://openalex.org/W2101403720","https://openalex.org/W2101413510","https://openalex.org/W2103470975","https://openalex.org/W2104685421","https://openalex.org/W2105430590","https://openalex.org/W2107373516","https://openalex.org/W2107625881","https://openalex.org/W2110491903","https://openalex.org/W2110640625","https://openalex.org/W2111272289","https://openalex.org/W2111481536","https://openalex.org/W2113045203","https://openalex.org/W2113249117","https://openalex.org/W2113577317","https://openalex.org/W2114628856","https://openalex.org/W2115534911","https://openalex.org/W2115607127","https://openalex.org/W2115867396","https://openalex.org/W2116422958","https://openalex.org/W2116552560","https://openalex.org/W2116989960","https://openalex.org/W2117649547","https://openalex.org/W2117931147","https://openalex.org/W2118143380","https://openalex.org/W2118340386","https://openalex.org/W2119260049","https://openalex.org/W2119284252","https://openalex.org/W2119295924","https://openalex.org/W2121889667","https://openalex.org/W2122031852","https://openalex.org/W2122351989","https://openalex.org/W2122782850","https://openalex.org/W2126126419","https://openalex.org/W2126162952","https://openalex.org/W2126496496","https://openalex.org/W2127611110","https://openalex.org/W2128566951","https://openalex.org/W2128791737","https://openalex.org/W2128963767","https://openalex.org/W2133987610","https://openalex.org/W2134073082","https://openalex.org/W2134344512","https://openalex.org/W2135194969","https://openalex.org/W2135779274","https://openalex.org/W2136184845","https://openalex.org/W2136452679","https://openalex.org/W2137829134","https://openalex.org/W2139094884","https://openalex.org/W2140717014","https://openalex.org/W2142252231","https://openalex.org/W2142285934","https://openalex.org/W2145089843","https://openalex.org/W2145333947","https://openalex.org/W2146098592","https://openalex.org/W2147589320","https://openalex.org/W2147905210","https://openalex.org/W2148334175","https://openalex.org/W2148954435","https://openalex.org/W2152532561","https://openalex.org/W2153463811","https://openalex.org/W2153608030","https://openalex.org/W2155274044","https://openalex.org/W2155667578","https://openalex.org/W2159269805","https://openalex.org/W2160625381","https://openalex.org/W2160881772","https://openalex.org/W2163117716","https://openalex.org/W2164276385","https://openalex.org/W2165521761","https://openalex.org/W2165528446","https://openalex.org/W2166086043","https://openalex.org/W2166155213","https://openalex.org/W2166769784","https://openalex.org/W2166809557","https://openalex.org/W2166937493","https://openalex.org/W2167616973","https://openalex.org/W2167792193","https://openalex.org/W2167806590","https://openalex.org/W2167852809","https://openalex.org/W2168634382","https://openalex.org/W2169662947","https://openalex.org/W2170275957","https://openalex.org/W2171452069","https://openalex.org/W2183670135","https://openalex.org/W2186742434","https://openalex.org/W2232026888","https://openalex.org/W2260038117","https://openalex.org/W2332221637","https://openalex.org/W2337711722","https://openalex.org/W2419641319","https://openalex.org/W2440368138","https://openalex.org/W2614197161","https://openalex.org/W3029052526","https://openalex.org/W3144847119","https://openalex.org/W4297040010"],"related_works":["https://openalex.org/W1963832588","https://openalex.org/W7097633143","https://openalex.org/W4298272151","https://openalex.org/W4233466530","https://openalex.org/W2023229685","https://openalex.org/W2755271308","https://openalex.org/W1158020440","https://openalex.org/W2128791737","https://openalex.org/W4392167520","https://openalex.org/W3081121509"],"abstract_inverted_index":{"Ulcerative":[0],"colitis":[1],"(UC)":[2],"is":[3,29,60,65,268,348,372,408,433],"a":[4,34,123,197,236,265,316,332,422,486,497,540,580],"chronic":[5,48],"inflammation":[6],"of":[7,23,57,84,87,151,194,211,231,246,254,256,289,303,321,327,335,358,384,438,449,455,485,530,532,543,586,593,605],"the":[8,13,20,40,69,85,91,152,164,168,172,187,191,223,229,244,247,252,322,345,362,382,400,446,533,544,591],"colon":[9],"which":[10,38,314,371],"together":[11],"with":[12,128,134,158,222,308],"related":[14],"Crohn":[15],"s":[16,352],"disease":[17],"(CD)":[18],"represent":[19],"major":[21,292],"forms":[22],"Inflammatory":[24],"Bowel":[25],"Disease":[26],"(IBD).":[27],"IBD":[28],"believed":[30],"to":[31,44,67,73,80,97,143,167,171,214,242,277,301,361],"arise":[32],"in":[33,51,102,146,208,258,261,294,318,368,399,410,435,445,493,548,584],"dysfunctional":[35],"intestinal":[36],"barrier":[37],"allows":[39],"normal":[41],"gut":[42],"flora":[43],"trigger":[45],"an":[46,131],"unwanted":[47],"immune":[49],"response":[50],"genetically":[52],"susceptible":[53],"individuals.":[54],"The":[55,109,291,403],"cause":[56],"these":[58],"illnesses":[59],"unknown,":[61],"and":[62,119,260,274,310,391,420,441,451,489,528,536,595],"treatment":[63],"today":[64],"solely":[66],"alleviate":[68],"symptoms.":[70],"In":[71,249,415],"order":[72],"identify":[74,98],"biomarkers":[75],"that":[76,204,344,394,405],"could":[77],"help":[78],"us":[79],"further":[81,183],"our":[82],"understanding":[83],"pathophysiology":[86],"UC,":[88],"we":[89,234,417],"applied":[90],"subtractive":[92],"suppression":[93],"hybridization":[94],"(SSH)":[95],"method":[96],"UC-differentially":[99],"regulated":[100],"genes":[101,113,140,154,157],"colonic":[103],"mucosal":[104],"biopsy":[105],"specimens":[106],"(Paper":[107],"I).":[108],"331":[110,153],"differentially":[111],"expressed":[112],"were":[114,141,155,272,275],"grouped":[115],"into":[116],"functional":[117,287],"categories":[118],"when":[120],"analyzed":[121],"revealed":[122,196],"gene":[124,179,188,432,500],"expression":[125,253,407],"pattern":[126],"consistent":[127,221],"UC":[129,212,427,439],"as":[130,388],"inflammatory":[132,494],"disorder":[133,174],"altered":[135],"epithelial":[136],"homeostasis.":[137],"Interestingly,":[138,377],"21":[139],"found":[142,276,373],"be":[144,278,397],"involved":[145,398,547,583],"membrane":[147,364],"trafficking.":[148],"Moreover,":[149,324],"37":[150],"unknown":[156,178],"no":[159],"predicted":[160],"function.":[161],"Based":[162],"on":[163,374,381],"sequence":[165],"homology":[166],"WASP-protein":[169],"(connected":[170],"immunodeficiency":[173],"Wiskott-Aldrich":[175],"syndrome)":[176],"one":[177],"was":[180,206,241],"selected":[181],"for":[182,286,501],"investigation.":[184,238],"We":[185],"named":[186],"WAFL.":[189,290],"While":[190],"initial":[192],"characterization":[193],"WAFL":[195,205,257,300,306,328,351,359,378,395],"broad":[198],"tissue":[199,210,216,437],"expression,":[200],"qPCR":[201],"analysis":[202],"indicated":[203],"upregulated":[207,434],"inflamed":[209,215,436],"compared":[213],"from":[217,426],"CD":[218],"patients":[219,440],"(i.e.":[220],"SSH":[224],"data).":[225],"To":[226],"learn":[227],"about":[228],"function":[230],"this":[232,413],"protein":[233,312,492,538,582],"initiated":[235],"detailed":[237],"One":[239],"approach":[240],"obtain":[243],"structure":[245],"protein.":[248],"Paper":[250,297],"II,":[251],"regions":[255],"E.coli,":[259],"insect":[262],"cells":[263,325],"via":[264],"baculoviral":[266],"system,":[267],"described.":[269],"These":[270],"peptides":[271],"purified":[273],"folded":[279],"correctly.":[280],"They":[281],"have":[282,418],"subsequently":[283],"been":[284],"used":[285],"tests":[288],"finding":[293],"my":[295],"thesis,":[296],"III,":[298],"links":[299],"regulation":[302,585],"early":[304,375,452,549,587],"endosomes.":[305,323,376,453],"interacts":[307],"actin":[309,594],"WASP-interacting":[311],"(WIP),":[313],"implies":[315],"role":[317],"actin-based":[319],"transport":[320,334,589],"depleted":[326],"by":[329,350],"RNAi":[330],"exhibited":[331],"disturbed":[333],"endocytic":[336,588],"cargo":[337],"towards":[338],"lysosomes.":[339],"Protein":[340],"mapping":[341],"experiments":[342],"showed":[343],"endosome":[346],"localization":[347],"mediated":[349],"central":[353],"coiled-coil":[354],"domain.":[355],"This":[356,430],"domain":[357],"binds":[360],"integral":[363],"components":[365],"monophosphorylated":[366],"phosphatidylinositols,":[367],"particular":[369],"PtdIns(3)P":[370],"appears":[379],"also":[380],"phagosome":[383],"invasive":[385],"bacteria":[386],"such":[387],"Salmonella,":[389],"Yersinia,":[390],"Shigella":[392],"indicating":[393],"may":[396],"phagocytosis":[401],"process.":[402],"observation":[404],"induced":[406],"observed":[409],"macrophages":[411],"support":[412],"possibility.":[414],"conclusion,":[416],"identified":[419],"characterized":[421],"novel":[423,541],"gene,":[424],"WAFL,":[425,539,579],"bioptic":[428],"material.":[429],"interesting":[431],"has":[442],"potential":[443,498],"functions":[444],"correct":[447],"processing":[448],"phagosomes":[450],"List":[454],"scientific":[456],"papers":[457],"I.":[458],"Viklund":[459,520,553],"IM,":[460,521,554],"Kuznetsov":[461],"NV,":[462],"L\u00f6fberg":[463],"R,":[464,468],"Daperno":[465],"M,":[466,470,472,477,568],"Sostegni":[467],"Astegiano":[469],"Rizzetto":[471],"von":[473,478],"Stein":[474,479],"O,":[475],"DAmato":[476,567],"P,":[480,556,572],"Pettersson":[481,522,576],"S":[482,577],"(2008).":[483,578],"Identification":[484],"new":[487,581],"WASP":[488,545],"FKBP-like":[490,537],"(WAFL)":[491],"bowel":[495],"disease:":[496],"marker":[499],"ulcerative":[502],"colitis.":[503],"Int":[504],"J":[505],"Colorectal":[506],"Dis.":[507],"23(10):":[508],"921-30.":[509],"Epub":[510,603],"2008":[511],"Jul":[512],"25":[513],"https://pubmed.ncbi.nlm.nih.gov/18654788":[514],"II.":[515],"Kopec":[516,561],"J,":[517,562],"\u00c5gren":[518],"D,":[519,564],"S,":[523],"Schneider":[524,565],"G":[525],"(2009).":[526],"Expression":[527],"purification":[529],"domains":[531],"human":[534],"WASP-":[535],"member":[542],"family":[546],"endocytosis.":[550],"[Submitted]":[551],"III.":[552],"Aspenstr\u00f6m":[555],"Meas-Yedid":[557],"V,":[558],"Zhang":[559],"B,":[560],"Agren":[563],"G,":[566],"Olivo-Marin":[569],"JC,":[570],"Sansonetti":[571],"Van":[573],"Nhieu":[574],"GT,":[575],"at":[590],"intersection":[592],"microtubule":[596],"dynamics.":[597],"Exp":[598],"Cell":[599],"Res.":[600],"Dec":[601],"16:":[602],"ahead":[604],"print":[606],"https://pubmed.ncbi.nlm.nih.gov/19121306":[607]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
