{"id":"https://openalex.org/W2124157676","doi":"https://doi.org/10.1016/s0958-1669(99)00004-x","title":"Applications of yeast in biotechnology: protein production and genetic analysis","display_name":"Applications of yeast in biotechnology: protein production and genetic analysis","publication_year":1999,"publication_date":"1999-10-01","ids":{"openalex":"https://openalex.org/W2124157676","doi":"https://doi.org/10.1016/s0958-1669(99)00004-x","mag":"2124157676","pmid":"https://pubmed.ncbi.nlm.nih.gov/10508632"},"language":"en","primary_location":{"id":"doi:10.1016/s0958-1669(99)00004-x","doi":"https://doi.org/10.1016/s0958-1669(99)00004-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0958-1669(99)00004-x","pdf_url":null,"source":{"id":"https://openalex.org/S23939942","display_name":"Current Opinion in Biotechnology","issn_l":"0958-1669","issn":["0958-1669","1879-0429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Biotechnology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108514651","display_name":"Geoffrey P. Lin Cereghino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geoffrey P Lin Cereghino","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology Oregon Graduate Institute of Science and Technology 20 000 NW Walker Road, Beaverton, Oregon, 7006-8921, USA. geoffc@bmb.ogi.edu","Department of Biochemistry and Molecular Biology Oregon Graduate Institute of Science and Technology 20 000 NW Walker Road, Beaverton, Oregon, 7006-8921, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology Oregon Graduate Institute of Science and Technology 20 000 NW Walker Road, Beaverton, Oregon, 7006-8921, USA. geoffc@bmb.ogi.edu","institution_ids":[]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology Oregon Graduate Institute of Science and Technology 20 000 NW Walker Road, Beaverton, Oregon, 7006-8921, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"James M Cregg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"James M Cregg","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and Technology, 20 000 NW Walker Road, Beaverton, Oregon 7006-8921, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and Technology, 20 000 NW Walker Road, Beaverton, Oregon 7006-8921, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4530,"currency":"USD","value_usd":4530},"apc_paid":null,"fwci":0.4885,"has_fulltext":false,"cited_by_count":175,"citation_normalized_percentile":{"value":0.47612425,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"10","issue":"5","first_page":"422","last_page":"427"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12668","display_name":"Yeasts and Rust Fungi Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/yeast","display_name":"yeast","score":0.7039999961853027},{"id":"https://openalex.org/keywords/protein-expression-systems","display_name":"protein expression systems","score":0.6430000066757202},{"id":"https://openalex.org/keywords/yeast-surface-display","display_name":"yeast surface display","score":0.9200000166893005},{"id":"https://openalex.org/keywords/two-hybrid-system","display_name":"two-hybrid system","score":0.8769999742507935},{"id":"https://openalex.org/keywords/genetic-analysis","display_name":"genetic analysis","score":0.746999979019165},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.9219092726707458},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.500324010848999},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.49965763092041016},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4981417655944824},{"id":"https://openalex.org/C174851938","wikidata":"https://www.wikidata.org/wiki/Q1337844","display_name":"Two-hybrid screening","level":3,"score":0.4116431474685669},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32518649101257324},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3200446367263794},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.12462800741195679}],"mesh":[{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010843","descriptor_name":"Pichia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015202","descriptor_name":"Protein Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0958-1669(99)00004-x","doi":"https://doi.org/10.1016/s0958-1669(99)00004-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0958-1669(99)00004-x","pdf_url":null,"source":{"id":"https://openalex.org/S23939942","display_name":"Current Opinion in Biotechnology","issn_l":"0958-1669","issn":["0958-1669","1879-0429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Biotechnology","raw_type":"journal-article"},{"id":"pmid:10508632","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10508632","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in biotechnology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G124184625","display_name":"PEROXISOME BIOGENESIS IN YEAST","funder_award_id":"R01DK043698","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7204892773","display_name":null,"funder_award_id":"ER20334","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G907708562","display_name":"REGULATION OF MAGANESE PEROXIDASE GENE EXPRESSION","funder_award_id":"F32ES005759","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W206279403","https://openalex.org/W655606259","https://openalex.org/W1564078780","https://openalex.org/W1926121210","https://openalex.org/W1971498704","https://openalex.org/W1983621817","https://openalex.org/W1987018006","https://openalex.org/W1990789777","https://openalex.org/W1991245779","https://openalex.org/W2000266693","https://openalex.org/W2014893007","https://openalex.org/W2016007765","https://openalex.org/W2021509703","https://openalex.org/W2024535650","https://openalex.org/W2026259690","https://openalex.org/W2027469872","https://openalex.org/W2028469300","https://openalex.org/W2034309871","https://openalex.org/W2040787259","https://openalex.org/W2041644002","https://openalex.org/W2041776594","https://openalex.org/W2049019178","https://openalex.org/W2064577218","https://openalex.org/W2068109582","https://openalex.org/W2081635117","https://openalex.org/W2084693864","https://openalex.org/W2089312229","https://openalex.org/W2092846883","https://openalex.org/W2096211374","https://openalex.org/W2106464570","https://openalex.org/W2128817262","https://openalex.org/W2143342414","https://openalex.org/W2155095111","https://openalex.org/W2156616278","https://openalex.org/W2161779477","https://openalex.org/W2166266450","https://openalex.org/W2392702874","https://openalex.org/W2399538424","https://openalex.org/W2472729818","https://openalex.org/W3098021590","https://openalex.org/W6679148664"],"related_works":["https://openalex.org/W2427197815","https://openalex.org/W2368967291","https://openalex.org/W4226237888","https://openalex.org/W4389099008","https://openalex.org/W4205294735","https://openalex.org/W2615151684","https://openalex.org/W4226047149","https://openalex.org/W2382069353","https://openalex.org/W3137637493","https://openalex.org/W610330898"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}