{"id":"https://openalex.org/W2124014266","doi":"https://doi.org/10.1183/09031936.02.00089802","title":"Vascular endothelial growth factor mRNA and protein expression in airway epithelial cell linesin vitro","display_name":"Vascular endothelial growth factor mRNA and protein expression in airway epithelial cell linesin vitro","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W2124014266","doi":"https://doi.org/10.1183/09031936.02.00089802","mag":"2124014266","pmid":"https://pubmed.ncbi.nlm.nih.gov/12503703"},"language":"en","primary_location":{"id":"doi:10.1183/09031936.02.00089802","doi":"https://doi.org/10.1183/09031936.02.00089802","is_oa":false,"landing_page_url":"https://doi.org/10.1183/09031936.02.00089802","pdf_url":null,"source":{"id":"https://openalex.org/S4210207896","display_name":"European Respiratory Journal","issn_l":"0903-1936","issn":["0903-1936","1399-3003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317833","host_organization_name":"European Respiratory Society","host_organization_lineage":["https://openalex.org/P4310317833"],"host_organization_lineage_names":["European Respiratory Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Respiratory Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"S. Koyama","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Koyama","raw_affiliation_strings":["Pulmonary Section, The National Chuushin Matsumoto Hospital, Toyooka, Matsumoto, Japan. yskoyama@go.tvm.ne.jp","Pulmonary Section, The National Chuushin Matsumoto Hospital, Toyooka, Matsumoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary Section, The National Chuushin Matsumoto Hospital, Toyooka, Matsumoto, Japan. yskoyama@go.tvm.ne.jp","institution_ids":[]},{"raw_affiliation_string":"Pulmonary Section, The National Chuushin Matsumoto Hospital, Toyooka, Matsumoto, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112294902","display_name":"Eichi Sato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"E. Sato","raw_affiliation_strings":["Kyoto University, Dept of Res-piratory Medicine, Graduate School of Medicine, Kyoto, Japan","The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University, Dept of Res-piratory Medicine, Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074596107","display_name":"Akihiro Tsukadaira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A. Tsukadaira","raw_affiliation_strings":["Kyoto University, Dept of Res-piratory Medicine, Graduate School of Medicine, Kyoto, Japan","The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University, Dept of Res-piratory Medicine, Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011175722","display_name":"Masayuki Haniuda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Haniuda","raw_affiliation_strings":["The National Chuushin Matsumoto Hospital, Matsumoto,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Chuushin Matsumoto Hospital, Matsumoto,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079901202","display_name":"Hiroki Numanami","orcid":"https://orcid.org/0000-0002-9097-9720","observed_orcids":["https://orcid.org/0000-0002-9097-9720"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Numanami","raw_affiliation_strings":["The National Chuushin Matsumoto Hospital, Matsumoto,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Chuushin Matsumoto Hospital, Matsumoto,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110341016","display_name":"Makoto Kurai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Kurai","raw_affiliation_strings":["The National Chuushin Matsumoto Hospital, Matsumoto,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The National Chuushin Matsumoto Hospital, Matsumoto,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"S. Nagai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"S. Nagai","raw_affiliation_strings":["The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }","Pulmonary Section The National Chuushin Matsumoto Hospital 811 Kotobuki Toyooka Matsumoto 399-0021 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }","institution_ids":["https://openalex.org/I137975476"]},{"raw_affiliation_string":"Pulmonary Section The National Chuushin Matsumoto Hospital 811 Kotobuki Toyooka Matsumoto 399-0021 Japan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048804892","display_name":"Taisuke Izumi","orcid":"https://orcid.org/0000-0001-8193-0813","observed_orcids":["https://orcid.org/0000-0001-8193-0813"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Izumi","raw_affiliation_strings":["The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }","Pulmonary Section The National Chuushin Matsumoto Hospital 811 Kotobuki Toyooka Matsumoto 399-0021 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Dept of Internal Medicine, Shinshu Univer-sity School of Medicine, Matsumoto, and }","institution_ids":["https://openalex.org/I137975476"]},{"raw_affiliation_string":"Pulmonary Section The National Chuushin Matsumoto Hospital 811 Kotobuki Toyooka Matsumoto 399-0021 Japan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.957,"has_fulltext":false,"cited_by_count":79,"citation_normalized_percentile":{"value":0.69539453,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"20","issue":"6","first_page":"1449","last_page":"1456"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":1.0},{"id":"https://openalex.org/keywords/airway-epithelial-cells","display_name":"airway epithelial cells","score":0.9169999957084656},{"id":"https://openalex.org/keywords/beas-2b-cells","display_name":"BEAS-2B cells","score":0.9340000152587891},{"id":"https://openalex.org/keywords/a549-cells","display_name":"A549 cells","score":1.0},{"id":"https://openalex.org/keywords/vegf-secretion","display_name":"VEGF secretion","score":0.8019999861717224},{"id":"https://openalex.org/keywords/vegf-mrna-expression","display_name":"VEGF mRNA expression","score":0.9240000247955322},{"id":"https://openalex.org/keywords/vegf-isoforms","display_name":"VEGF isoforms","score":0.878000020980835},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8489999771118164},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.9869999885559082},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neutrophil-elastase","display_name":"neutrophil elastase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bradykinin","display_name":"bradykinin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/keratinocyte-growth-factor","display_name":"keratinocyte growth factor","score":0.9940000176429749},{"id":"https://openalex.org/keywords/vascular-permeability","display_name":"vascular permeability","score":0.9729999899864197},{"id":"https://openalex.org/keywords/airway-remodeling","display_name":"airway remodeling","score":0.6460000276565552},{"id":"https://openalex.org/keywords/pulmonary-inflammation","display_name":"lung inflammation","score":0.36800000071525574}],"concepts":[{"id":"https://openalex.org/C2777025900","wikidata":"https://www.wikidata.org/wiki/Q29725","display_name":"Vascular endothelial growth factor","level":3,"score":0.7791948914527893},{"id":"https://openalex.org/C146285616","wikidata":"https://www.wikidata.org/wiki/Q7916455","display_name":"Vascular endothelial growth factor A","level":4,"score":0.5494800806045532},{"id":"https://openalex.org/C81729549","wikidata":"https://www.wikidata.org/wiki/Q4649475","display_name":"A549 cell","level":3,"score":0.458948016166687},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.44291508197784424},{"id":"https://openalex.org/C113045295","wikidata":"https://www.wikidata.org/wiki/Q7916465","display_name":"Vascular permeability","level":2,"score":0.4334736764431},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.4221893846988678},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4043009579181671},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3897295594215393},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37897542119026184},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3542655110359192},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3201562762260437},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2880837917327881},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27685871720314026},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16085395216941833},{"id":"https://openalex.org/C167734588","wikidata":"https://www.wikidata.org/wiki/Q4356503","display_name":"VEGF receptors","level":2,"score":0.09074816107749939},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008222","descriptor_name":"Lymphokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008222","descriptor_name":"Lymphokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016228","descriptor_name":"Endothelial Growth Factors","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016228","descriptor_name":"Endothelial Growth Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D042442","descriptor_name":"Vascular Endothelial Growth Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042461","descriptor_name":"Vascular Endothelial Growth Factor A","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1183/09031936.02.00089802","doi":"https://doi.org/10.1183/09031936.02.00089802","is_oa":false,"landing_page_url":"https://doi.org/10.1183/09031936.02.00089802","pdf_url":null,"source":{"id":"https://openalex.org/S4210207896","display_name":"European Respiratory Journal","issn_l":"0903-1936","issn":["0903-1936","1399-3003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317833","host_organization_name":"European Respiratory Society","host_organization_lineage":["https://openalex.org/P4310317833"],"host_organization_lineage_names":["European Respiratory Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Respiratory Journal","raw_type":"journal-article"},{"id":"pmid:12503703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12503703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The European respiratory journal","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.573.1908","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.573.1908","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://erj.ersjournals.com/content/20/6/1449.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W46493756","https://openalex.org/W276558408","https://openalex.org/W1482104159","https://openalex.org/W1504802106","https://openalex.org/W1537712767","https://openalex.org/W1552383593","https://openalex.org/W1593130318","https://openalex.org/W1670891845","https://openalex.org/W1840610614","https://openalex.org/W1957871175","https://openalex.org/W1967365012","https://openalex.org/W1977980079","https://openalex.org/W1983763042","https://openalex.org/W1994936867","https://openalex.org/W1999223106","https://openalex.org/W2013038209","https://openalex.org/W2015344488","https://openalex.org/W2016904444","https://openalex.org/W2032193895","https://openalex.org/W2035649809","https://openalex.org/W2037141117","https://openalex.org/W2047922146","https://openalex.org/W2049191254","https://openalex.org/W2050159088","https://openalex.org/W2053613840","https://openalex.org/W2059944938","https://openalex.org/W2062594120","https://openalex.org/W2070039198","https://openalex.org/W2072446438","https://openalex.org/W2121594719","https://openalex.org/W2134812217","https://openalex.org/W2139192008","https://openalex.org/W2171998177","https://openalex.org/W2186595875","https://openalex.org/W2198642767","https://openalex.org/W2202356825","https://openalex.org/W2343527743","https://openalex.org/W4245693946"],"related_works":["https://openalex.org/W7100796666","https://openalex.org/W1979502754","https://openalex.org/W1994038070","https://openalex.org/W1540387095","https://openalex.org/W2343527743","https://openalex.org/W1631154202","https://openalex.org/W7099954187","https://openalex.org/W2259285528","https://openalex.org/W1965244343","https://openalex.org/W2013625903"],"abstract_inverted_index":{"Vascular":[0],"endothelial":[1,232],"growth":[2,139,233],"factor":[3,95,140],"(VEGF)":[4],"plays":[5],"multifunctional":[6],"roles":[7],"in":[8,15,46,102,116,172,183,223],"vascular":[9,21,144,210,217,231],"permeability,":[10,145,218],"repair":[11,219],"and":[12,23,38,43,48,55,65,84,92,105,131,162,167,176,195,212,220],"remodelling":[13,221],"processes,":[14,222],"addition":[16],"to":[17,41,150,174],"the":[18,26,29,98,134,207],"maintenance":[19,208],"of":[20,31,57,73,100,136,180,209,226],"structure":[22,211],"function.":[24],"In":[25],"present":[27],"study,":[28],"potential":[30],"airway":[32,184,202],"epithelial":[33,185,203],"cell":[34],"lines,":[35],"BEAS-2B":[36,82],"cells":[37,83,86,149,186,204],"A549":[39,85],"cells,":[40],"release":[42,99,135,151],"express":[44],"VEGF":[45,58,75,88,101,110,153,181],"unstimulated":[47],"stimulated":[49,133,147],"conditions":[50,228],"was":[51,111,158,187],"evaluated.":[52],"The":[53,71,108,178],"secretion":[54],"expression":[56,179],"were":[59,76],"evaluated":[60],"by":[61,66,78,190,229],"enzyme-linked":[62],"immunosorbant":[63],"assay":[64],"reverse":[67],"transcriptase-polymerase":[68],"chain":[69],"reaction.":[70],"isoforms":[72],"released":[74,87,109],"determined":[77],"high-performance":[79],"liquid":[80],"chromatography.":[81],"constitutively.":[89],"Interleukin":[90],"(IL)-1beta":[91],"tumour":[93],"necrosis":[94],"(TNF)-alpha":[96],"augmented":[97,189],"a":[103,224],"time-":[104,161],"dose-dependent":[106],"manner.":[107],"165":[112],"amino":[113],"acid":[114,156],"residues":[115],"either":[117],"condition.":[118],"Pseudomonas":[119],"aeruginosa":[120],"lipopolysaccharide":[121],"(LPS),":[122],"interferon":[123],"(IFN)-gamma,":[124],"smoke":[125],"extract":[126],"(SE),":[127],"neutrophil":[128],"elastase":[129],"(NE),":[130],"bradykinin":[132],"VEGF.":[137,152],"Keracinocyte":[138],"(KGF),":[141],"which":[142],"reduces":[143],"also":[146,188],"both":[148,160],"messenger":[154],"ribonucleic":[155],"(mRNA)":[157],"expressed":[159],"dose-dependently":[163],"at":[164],"2":[165,170],"h,":[166],"declined":[168],"after":[169],"h":[171],"response":[173],"IL-1beta":[175],"TNF-alpha.":[177],"mRNA":[182],"LPS,":[191],"IFN-gamma,":[192],"SE,":[193],"NE,":[194],"KGF":[196],"stimulation.":[197],"These":[198],"data":[199],"suggest":[200],"that":[201],"may":[205],"regulate":[206],"function,":[213],"as":[214,216],"well":[215],"variety":[225],"lung":[227],"expressing":[230],"factor.":[234]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}