{"id":"https://openalex.org/W2123973628","doi":null,"title":"Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of inflammation","display_name":"Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of inflammation","publication_year":2013,"publication_date":"2013-11-14","ids":{"openalex":"https://openalex.org/W2123973628","mag":"2123973628"},"language":"en","primary_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/33116","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/33116","pdf_url":"http://hdl.handle.net/2077/33116","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2077/33116","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027195583","display_name":"Martina Sundqvist","orcid":"https://orcid.org/0000-0002-0859-0792","observed_orcids":["https://orcid.org/0000-0002-0859-0792"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Martina Sundqvist","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0859-0792","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5027195583"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12387","display_name":"Galectins and Cancer Biology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracellular-reactive-oxygen-species","display_name":"intracellular reactive oxygen species","score":0.8790000081062317},{"id":"https://openalex.org/keywords/galectin-3","display_name":"galectin-3","score":0.996999979019165},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5099999904632568},{"id":"https://openalex.org/keywords/neutrophil-priming","display_name":"neutrophil priming","score":0.8600000143051147},{"id":"https://openalex.org/keywords/sterile-inflammation","display_name":"sterile inflammation","score":0.6010000109672546},{"id":"https://openalex.org/keywords/pfapa-syndrome","display_name":"PFAPA syndrome","score":0.828000009059906},{"id":"https://openalex.org/keywords/chronic-granulomatous-disease","display_name":"chronic granulomatous disease","score":0.9509999752044678},{"id":"https://openalex.org/keywords/mitochondrial-ros","display_name":"mitochondrial reactive oxygen species","score":0.8420000076293945},{"id":"https://openalex.org/keywords/neutrophil-apoptosis","display_name":"neutrophil apoptosis","score":0.8809999823570251},{"id":"https://openalex.org/keywords/vaginal-delivery","display_name":"vaginal delivery","score":0.49300000071525574},{"id":"https://openalex.org/keywords/neutrophil-activation","display_name":"neutrophil activation","score":0.4189999997615814},{"id":"https://openalex.org/keywords/autoinflammatory-disease","display_name":"autoinflammatory disease","score":0.6990000009536743},{"id":"https://openalex.org/keywords/phagocytes","display_name":"phagocytes","score":0.4429999887943268}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6877151727676392},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6548617482185364},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5631234049797058},{"id":"https://openalex.org/C156293190","wikidata":"https://www.wikidata.org/wiki/Q83138026","display_name":"Galectin","level":2,"score":0.5260379314422607},{"id":"https://openalex.org/C134897094","wikidata":"https://www.wikidata.org/wiki/Q7003141","display_name":"Neutrophil extracellular traps","level":3,"score":0.5175299048423767},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5098906755447388},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.5021941661834717},{"id":"https://openalex.org/C168261976","wikidata":"https://www.wikidata.org/wiki/Q5347407","display_name":"Efferocytosis","level":4,"score":0.45700159668922424},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3987806737422943},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.3620874285697937},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.13226372003555298},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09723863005638123}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:gupea.ub.gu.se:2077/33116","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/33116","pdf_url":"http://hdl.handle.net/2077/33116","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},{"id":"mag:2123973628","doi":null,"is_oa":false,"landing_page_url":"https://gupea.ub.gu.se/bitstream/2077/33116/1/gupea_2077_33116_1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/33116","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/33116","pdf_url":"http://hdl.handle.net/2077/33116","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2123973628.pdf","grobid_xml":"https://content.openalex.org/works/W2123973628.grobid-xml"},"referenced_works_count":255,"referenced_works":["https://openalex.org/W17465580","https://openalex.org/W56630701","https://openalex.org/W59799898","https://openalex.org/W85194748","https://openalex.org/W137223049","https://openalex.org/W146301169","https://openalex.org/W303205414","https://openalex.org/W1488793212","https://openalex.org/W1502917309","https://openalex.org/W1505835018","https://openalex.org/W1507631824","https://openalex.org/W1511134032","https://openalex.org/W1514224413","https://openalex.org/W1523714793","https://openalex.org/W1524848610","https://openalex.org/W1541731901","https://openalex.org/W1551392207","https://openalex.org/W1567652101","https://openalex.org/W1573103899","https://openalex.org/W1576411973","https://openalex.org/W1577692989","https://openalex.org/W1583760582","https://openalex.org/W1593858768","https://openalex.org/W1597610606","https://openalex.org/W1607784912","https://openalex.org/W1615239198","https://openalex.org/W1716982404","https://openalex.org/W1745634660","https://openalex.org/W1769382158","https://openalex.org/W1774714795","https://openalex.org/W1797816400","https://openalex.org/W1870318190","https://openalex.org/W1939797153","https://openalex.org/W1945626132","https://openalex.org/W1963503118","https://openalex.org/W1964560377","https://openalex.org/W1967291007","https://openalex.org/W1969005800","https://openalex.org/W1969343364","https://openalex.org/W1970338512","https://openalex.org/W1970608687","https://openalex.org/W1970962136","https://openalex.org/W1972467243","https://openalex.org/W1973798901","https://openalex.org/W1974126299","https://openalex.org/W1974191557","https://openalex.org/W1974634741","https://openalex.org/W1976480410","https://openalex.org/W1976646654","https://openalex.org/W1976692397","https://openalex.org/W1977005214","https://openalex.org/W1978462186","https://openalex.org/W1979473901","https://openalex.org/W1979487024","https://openalex.org/W1980333945","https://openalex.org/W1981120411","https://openalex.org/W1981150151","https://openalex.org/W1983044519","https://openalex.org/W1985538633","https://openalex.org/W1985556897","https://openalex.org/W1985965035","https://openalex.org/W1987111733","https://openalex.org/W1988027744","https://openalex.org/W1988230895","https://openalex.org/W1990578525","https://openalex.org/W1990804638","https://openalex.org/W1991033052","https://openalex.org/W1991049513","https://openalex.org/W1992006091","https://openalex.org/W1995819865","https://openalex.org/W1996055367","https://openalex.org/W1996830451","https://openalex.org/W1998280863","https://openalex.org/W1998438811","https://openalex.org/W2000041349","https://openalex.org/W2001819260","https://openalex.org/W2002056653","https://openalex.org/W2003099813","https://openalex.org/W2003712884","https://openalex.org/W2003758590","https://openalex.org/W2004536682","https://openalex.org/W2004763493","https://openalex.org/W2005030361","https://openalex.org/W2006051699","https://openalex.org/W2006241370","https://openalex.org/W2006714159","https://openalex.org/W2008243630","https://openalex.org/W2008816114","https://openalex.org/W2008981570","https://openalex.org/W2009388678","https://openalex.org/W2010154445","https://openalex.org/W2011002068","https://openalex.org/W2011006768","https://openalex.org/W2012883414","https://openalex.org/W2012915496","https://openalex.org/W2013679110","https://openalex.org/W2015404118","https://openalex.org/W2018659869","https://openalex.org/W2018915861","https://openalex.org/W2020134925","https://openalex.org/W2020969008","https://openalex.org/W2021069555","https://openalex.org/W2024559112","https://openalex.org/W2024687151","https://openalex.org/W2027031925","https://openalex.org/W2027039566","https://openalex.org/W2027912654","https://openalex.org/W2029210239","https://openalex.org/W2030064249","https://openalex.org/W2030463167","https://openalex.org/W2031256148","https://openalex.org/W2031604270","https://openalex.org/W2032227357","https://openalex.org/W2033698154","https://openalex.org/W2034759328","https://openalex.org/W2035279383","https://openalex.org/W2035664000","https://openalex.org/W2037821908","https://openalex.org/W2038753879","https://openalex.org/W2038826974","https://openalex.org/W2040937550","https://openalex.org/W2040957252","https://openalex.org/W2041084308","https://openalex.org/W2041153462","https://openalex.org/W2041912408","https://openalex.org/W2042107686","https://openalex.org/W2042122319","https://openalex.org/W2042916155","https://openalex.org/W2043937148","https://openalex.org/W2045362817","https://openalex.org/W2046149592","https://openalex.org/W2048265787","https://openalex.org/W2048791692","https://openalex.org/W2049472148","https://openalex.org/W2051185450","https://openalex.org/W2052012325","https://openalex.org/W2052619864","https://openalex.org/W2055547672","https://openalex.org/W2056088720","https://openalex.org/W2057148382","https://openalex.org/W2057452979","https://openalex.org/W2058821788","https://openalex.org/W2059365540","https://openalex.org/W2060273459","https://openalex.org/W2061460842","https://openalex.org/W2062152303","https://openalex.org/W2063356775","https://openalex.org/W2063572291","https://openalex.org/W2063636552","https://openalex.org/W2065239649","https://openalex.org/W2068470913","https://openalex.org/W2068505049","https://openalex.org/W2070357530","https://openalex.org/W2071498075","https://openalex.org/W2072022640","https://openalex.org/W2074580772","https://openalex.org/W2075840479","https://openalex.org/W2079356203","https://openalex.org/W2082024708","https://openalex.org/W2082027338","https://openalex.org/W2082324941","https://openalex.org/W2082426990","https://openalex.org/W2085194212","https://openalex.org/W2085864038","https://openalex.org/W2086049503","https://openalex.org/W2086537933","https://openalex.org/W2089782191","https://openalex.org/W2090576960","https://openalex.org/W2091918640","https://openalex.org/W2092984629","https://openalex.org/W2097030555","https://openalex.org/W2099077399","https://openalex.org/W2100936098","https://openalex.org/W2101133312","https://openalex.org/W2101541453","https://openalex.org/W2102425902","https://openalex.org/W2102862146","https://openalex.org/W2103586762","https://openalex.org/W2103650131","https://openalex.org/W2104934425","https://openalex.org/W2105269693","https://openalex.org/W2105545932","https://openalex.org/W2106060680","https://openalex.org/W2106341310","https://openalex.org/W2106931931","https://openalex.org/W2106949285","https://openalex.org/W2108585076","https://openalex.org/W2112530582","https://openalex.org/W2113016607","https://openalex.org/W2116274871","https://openalex.org/W2117281033","https://openalex.org/W2117660489","https://openalex.org/W2117832286","https://openalex.org/W2119062616","https://openalex.org/W2119800239","https://openalex.org/W2119828139","https://openalex.org/W2119998318","https://openalex.org/W2120094806","https://openalex.org/W2122287804","https://openalex.org/W2122462682","https://openalex.org/W2124377923","https://openalex.org/W2125099471","https://openalex.org/W2125894404","https://openalex.org/W2126468017","https://openalex.org/W2126578659","https://openalex.org/W2127761598","https://openalex.org/W2128730970","https://openalex.org/W2129385154","https://openalex.org/W2131499677","https://openalex.org/W2131917465","https://openalex.org/W2132340572","https://openalex.org/W2132344671","https://openalex.org/W2132828036","https://openalex.org/W2134735862","https://openalex.org/W2135791851","https://openalex.org/W2140024173","https://openalex.org/W2141309671","https://openalex.org/W2141429692","https://openalex.org/W2141506792","https://openalex.org/W2142280282","https://openalex.org/W2142461048","https://openalex.org/W2142633227","https://openalex.org/W2143251020","https://openalex.org/W2145664163","https://openalex.org/W2146401589","https://openalex.org/W2146495023","https://openalex.org/W2147727128","https://openalex.org/W2148587509","https://openalex.org/W2150594596","https://openalex.org/W2153467733","https://openalex.org/W2153869022","https://openalex.org/W2154229994","https://openalex.org/W2156192474","https://openalex.org/W2158500407","https://openalex.org/W2159587574","https://openalex.org/W2161894245","https://openalex.org/W2164158176","https://openalex.org/W2164617640","https://openalex.org/W2164802863","https://openalex.org/W2165930294","https://openalex.org/W2167474740","https://openalex.org/W2167992469","https://openalex.org/W2170936782","https://openalex.org/W2171595787","https://openalex.org/W2187896211","https://openalex.org/W2242165656","https://openalex.org/W2270245312","https://openalex.org/W2326010521","https://openalex.org/W2407015583","https://openalex.org/W2410220461","https://openalex.org/W2463249350","https://openalex.org/W2624936342","https://openalex.org/W4229886691","https://openalex.org/W4247088117","https://openalex.org/W4252859460"],"related_works":["https://openalex.org/W2895386154","https://openalex.org/W4366352655","https://openalex.org/W1969005800","https://openalex.org/W2407015583","https://openalex.org/W4220681723","https://openalex.org/W1541731901","https://openalex.org/W1571205290","https://openalex.org/W58922472","https://openalex.org/W2956584982","https://openalex.org/W2896686177"],"abstract_inverted_index":{"The":[0,111],"focus":[1,18],"for":[2],"this":[3,70,250],"PhD":[4],"project":[5],"has":[6,174,365],"been":[7,46,175,315,366],"to":[8,55,88,96,127,150,177,199,203,284,347,368,381,391],"investigate":[9],"neutrophil":[10,29,238,310],"functions":[11,93,375],"in":[12,41,62,79,94,122,162,171,201,249,305,376,379],"different":[13,359],"(inflammatory)":[14],"settings":[15,360],"with":[16,31,264,312],"specific":[17],"on":[19,117,385],"phagocyte-derived":[20],"intracellular":[21,159],"reactive":[22],"oxygen":[23],"species":[24],"(ROS)":[25],"as":[26,28,50,146],"well":[27],"interaction":[30,338],"the":[32,37,63,133,163,301,318,342,348,392],"inflammatory":[33,81,291,303,387,396],"mediator":[34],"galectin-3.":[35,137],"\\nNeutrophils,":[36],"most":[38,252],"abundant":[39],"leukocyte":[40],"human":[42],"blood,":[43],"have":[44,314],"traditionally":[45],"viewed":[47],"upon":[48],"mainly":[49],"professional":[51],"phagocytes,":[52],"being":[53,105],"able":[54,87],"degrade":[56,151],"invading":[57,152],"microbes,":[58,153],"and":[59,92,98,168,227,231,243,317,341,363],"thus":[60],"essential":[61],"defence":[64],"against":[65],"infection.":[66],"However,":[67],"studies":[68],"including":[69],"thesis,":[71],"suggest":[72],"that":[73,123,182,233,260,296,322,389],"neutrophils":[74,113,141,155,185,357],"are":[75,84,142,246,282],"important":[76],"players":[77],"also":[78,157,287],"sterile":[80,290,302],"conditions.":[82,292],"\\nNeutrophils":[83],"versatile":[85],"cells,":[86,378],"change":[89],"their":[90,118],"appearance":[91],"relation":[95],"time":[97],"localization.":[99],"Their":[100],"phenotype":[101,209],"can":[102,125,156,328],"vary":[103],"from":[104,186,262,289,358],"resting,":[106],"preactivated/primed":[107],"or":[108],"fully":[109],"activated.":[110],"primed":[112,196,208],"display":[114,194,274],"increased":[115,275],"receptors":[116],"cell":[119,349],"surfaces":[120],"resulting":[121],"they":[124],"respond":[126],"a":[128,169,195,218,323,334],"variety":[129],"of":[130,145,165,237,270,277,326,337,356,361,395],"stimuli,":[131],"e.g.,":[132],"\u03b2-galactoside":[134],"binding":[135,346],"lectin":[136],"ROS":[138,160,272,298],"produced":[139,149],"by":[140,190,212],"primarily":[143],"thought":[144],"toxic":[147],"metabolites":[148],"however,":[154],"produce":[158],"(icROS)":[161],"absence":[164],"microbial":[166],"uptake":[167],"decrease":[170],"these":[172,377],"icROS":[173,244],"correlated":[176],"inflammation.":[178],"\\nPaper":[179],"I":[180],"demonstrates":[181,232,259],"cord":[183],"blood":[184,205],"term":[187],"neonates":[188],"delivered":[189],"elective":[191],"Caesarean":[192],"section":[193],"phenotype,":[197],"responding":[198],"galectin-3,":[200],"contrast":[202],"adult":[204],"neutrophils.":[206],"This":[207],"is":[210,351],"accentuated":[211],"vaginal":[213],"delivery.":[214],"Paper":[215,257,293],"II":[216],"investigates":[217],"pediatric":[219],"autoinflammatory":[220],"syndrome,":[221],"periodic":[222],"fever,":[223],"aphthous":[224],"stomatitis,":[225],"pharyngitis":[226],"cervical":[228],"adenitis":[229],"(PFAPA),":[230],"three":[234],"key":[235],"aspects":[236],"function,":[239],"namely":[240],"apoptosis,":[241],"priming,":[242],"production,":[245,273],"all":[247],"altered":[248],"disease,":[251],"prominently":[253],"during":[254],"febrile":[255],"attacks.":[256],"III":[258,294],"phagocytes":[261],"patients":[263,281],"chronic":[265],"granulomatous":[266],"disease":[267,364],"(CGD),":[268],"devoid":[269],"antimicrobial":[271],"levels":[276],"mitochondrial-derived":[278],"ROS.":[279],"CGD":[280],"hyper-susceptible":[283],"infections,":[285],"but":[286],"suffer":[288],"suggests":[295],"mitochondrial":[297],"might":[299],"drive":[300],"manifestations":[304],"CGD.":[306],"In":[307],"paper":[308],"IV,":[309],"interactions":[311],"galectin-3":[313,327,330,340],"studied,":[316],"main":[319],"results":[320],"show":[321],"truncated":[324,343],"fragment":[325],"inhibit":[329],"induced":[331],"activity.":[332],"Further,":[333],"novel":[335],"type":[336],"between":[339],"form,":[344],"when":[345],"surface,":[350],"presented.":[352],"\\nIn":[353],"conclusion,":[354],"investigation":[355],"health":[362],"utilized":[367],"increase":[369],"our":[370],"detailed":[371],"knowledge":[372],"regarding":[373],"basic":[374],"addition":[380],"providing":[382],"new":[383],"information":[384],"severe":[386],"syndromes":[388],"contribute":[390],"overall":[393],"understanding":[394],"diseases.":[397]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}