{"id":"https://openalex.org/W2123687992","doi":"https://doi.org/10.1093/genetics/162.1.285","title":"Genetic Interaction Between Integrins and moleskin, a Gene Encoding a Drosophila Homolog of Importin-7","display_name":"Genetic Interaction Between Integrins and moleskin, a Gene Encoding a Drosophila Homolog of Importin-7","publication_year":2002,"publication_date":"2002-09-01","ids":{"openalex":"https://openalex.org/W2123687992","doi":"https://doi.org/10.1093/genetics/162.1.285","mag":"2123687992","pmid":"https://pubmed.ncbi.nlm.nih.gov/12242240","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1462259"},"language":"en","primary_location":{"id":"doi:10.1093/genetics/162.1.285","doi":"https://doi.org/10.1093/genetics/162.1.285","is_oa":false,"landing_page_url":"https://doi.org/10.1093/genetics/162.1.285","pdf_url":null,"source":{"id":"https://openalex.org/S65932378","display_name":"Genetics","issn_l":"0016-6731","issn":["0016-6731","1943-2631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019884843","display_name":"Scott Baker","orcid":"https://orcid.org/0000-0001-5085-3106","observed_orcids":["https://orcid.org/0000-0001-5085-3106"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott E Baker","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031960920","display_name":"James A. Lorenzen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A Lorenzen","raw_affiliation_strings":["Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037387572","display_name":"Steven W. Miller","orcid":"https://orcid.org/0000-0001-7610-6336","observed_orcids":["https://orcid.org/0000-0001-7610-6336"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven W Miller","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000590974","display_name":"Thomas A. Bunch","orcid":"https://orcid.org/0000-0002-6237-1427","observed_orcids":["https://orcid.org/0000-0002-6237-1427"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas A Bunch","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064438446","display_name":"Alison L. Jannuzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alison L Jannuzi","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032907445","display_name":"Mark H. Ginsberg","orcid":"https://orcid.org/0000-0002-5685-5417","observed_orcids":["https://orcid.org/0000-0002-5685-5417"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark H Ginsberg","raw_affiliation_strings":["Department of Vascular Biology, The Scripps Research Institute, La Jolla, California 92037"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Biology, The Scripps Research Institute, La Jolla, California 92037","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110803087","display_name":"Lizabeth A. Perkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lizabeth A Perkins","raw_affiliation_strings":["Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019083735","display_name":"Danny L. Brower","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Danny L Brower","raw_affiliation_strings":["Department of Biochemistry, University of Arizona, Tucson, Arizona 85721","Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243"]},{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5019083735"],"corresponding_institution_ids":["https://openalex.org/I138006243"],"apc_list":{"value":4477,"currency":"USD","value_usd":4477},"apc_paid":null,"fwci":0.955,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.73640743,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"162","issue":"1","first_page":"285","last_page":"296"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integrins","display_name":"integrins","score":0.7649999856948853},{"id":"https://openalex.org/keywords/importin-7","display_name":"IMP-7","score":0.9480000138282776},{"id":"https://openalex.org/keywords/shp2","display_name":"SHP2","score":0.6079999804496765},{"id":"https://openalex.org/keywords/corkscrew","display_name":"corkscrew","score":0.7480000257492065},{"id":"https://openalex.org/keywords/nuclear-translocation","display_name":"nuclear translocation","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9041256308555603},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.614970862865448},{"id":"https://openalex.org/C207177822","wikidata":"https://www.wikidata.org/wiki/Q5050812","display_name":"Genetic screen","level":4,"score":0.5863248705863953},{"id":"https://openalex.org/C91986751","wikidata":"https://www.wikidata.org/wiki/Q996011","display_name":"Imaginal disc","level":4,"score":0.5697338581085205},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.542128324508667},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5348092317581177},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5236353874206543},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.49436497688293457},{"id":"https://openalex.org/C97257150","wikidata":"https://www.wikidata.org/wiki/Q161358","display_name":"Wing","level":2,"score":0.4756854772567749},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4385926425457001},{"id":"https://openalex.org/C85528070","wikidata":"https://www.wikidata.org/wiki/Q643602","display_name":"Protein tyrosine phosphatase","level":3,"score":0.43343454599380493},{"id":"https://openalex.org/C57708383","wikidata":"https://www.wikidata.org/wiki/Q260182","display_name":"Null allele","level":4,"score":0.4261128604412079},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.33328133821487427},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.174094557762146},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.10516849160194397},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016153","descriptor_name":"Genes, Suppressor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028884","descriptor_name":"Karyopherins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D028884","descriptor_name":"Karyopherins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/genetics/162.1.285","doi":"https://doi.org/10.1093/genetics/162.1.285","is_oa":false,"landing_page_url":"https://doi.org/10.1093/genetics/162.1.285","pdf_url":null,"source":{"id":"https://openalex.org/S65932378","display_name":"Genetics","issn_l":"0016-6731","issn":["0016-6731","1943-2631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics","raw_type":"journal-article"},{"id":"pmid:12242240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12242240","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G213772183","display_name":null,"funder_award_id":"HL-48728","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G223908282","display_name":"Structure/Function Studies of the Integrin","funder_award_id":"R01GM042474","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6059490697","display_name":"DROSOPHILIA PS INTEGRIN FUNCTION","funder_award_id":"F32GM019149","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7570823048","display_name":"Receptor Tyrosine Kinase Regulation of Nuclear Import","funder_award_id":"R01GM061707","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G780268991","display_name":"CELL ADHESION MECHANISMS IN VASCULAR DISEASE","funder_award_id":"P01HL048728","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8203933614","display_name":"FUNCTIONAL ANALYSIS OF A PROTEIN TYROSINE PHOSPHATE","funder_award_id":"F32GM017901","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":79,"referenced_works":["https://openalex.org/W1493062728","https://openalex.org/W1585757291","https://openalex.org/W1711549471","https://openalex.org/W1866472634","https://openalex.org/W1909468734","https://openalex.org/W1926285529","https://openalex.org/W1963649273","https://openalex.org/W1965187800","https://openalex.org/W1968253797","https://openalex.org/W1976242955","https://openalex.org/W1980436648","https://openalex.org/W1987403356","https://openalex.org/W1987413856","https://openalex.org/W1991690400","https://openalex.org/W1999081109","https://openalex.org/W2001552205","https://openalex.org/W2004629227","https://openalex.org/W2016049505","https://openalex.org/W2017284082","https://openalex.org/W2017599124","https://openalex.org/W2018947638","https://openalex.org/W2025768025","https://openalex.org/W2029231027","https://openalex.org/W2029723738","https://openalex.org/W2036760739","https://openalex.org/W2037196975","https://openalex.org/W2042371710","https://openalex.org/W2048553981","https://openalex.org/W2052436795","https://openalex.org/W2057833663","https://openalex.org/W2058038345","https://openalex.org/W2060176983","https://openalex.org/W2063076755","https://openalex.org/W2067559925","https://openalex.org/W2067994205","https://openalex.org/W2071932086","https://openalex.org/W2079583982","https://openalex.org/W2079892535","https://openalex.org/W2081401313","https://openalex.org/W2082328100","https://openalex.org/W2083117403","https://openalex.org/W2091850954","https://openalex.org/W2092478868","https://openalex.org/W2093208114","https://openalex.org/W2097856283","https://openalex.org/W2099300824","https://openalex.org/W2101659312","https://openalex.org/W2102324547","https://openalex.org/W2105609521","https://openalex.org/W2106925642","https://openalex.org/W2108908409","https://openalex.org/W2111778285","https://openalex.org/W2114474216","https://openalex.org/W2116577449","https://openalex.org/W2122720918","https://openalex.org/W2123168425","https://openalex.org/W2131283226","https://openalex.org/W2135054831","https://openalex.org/W2137134545","https://openalex.org/W2138482225","https://openalex.org/W2140929616","https://openalex.org/W2145621796","https://openalex.org/W2146779790","https://openalex.org/W2147517839","https://openalex.org/W2148206240","https://openalex.org/W2151856952","https://openalex.org/W2154622534","https://openalex.org/W2159935247","https://openalex.org/W2160362282","https://openalex.org/W2160777888","https://openalex.org/W2163304270","https://openalex.org/W2165306451","https://openalex.org/W2170852571","https://openalex.org/W2185580285","https://openalex.org/W2188990683","https://openalex.org/W2189194581","https://openalex.org/W2728956820","https://openalex.org/W4213141530","https://openalex.org/W6857817545"],"related_works":["https://openalex.org/W2048553981","https://openalex.org/W2123168425","https://openalex.org/W2188990683","https://openalex.org/W2170852571","https://openalex.org/W1969542168","https://openalex.org/W2080592483","https://openalex.org/W2089043901","https://openalex.org/W34561060","https://openalex.org/W2320992159","https://openalex.org/W7073864068"],"abstract_inverted_index":{"The":[0],"Drosophila":[1,120],"PS1":[2],"and":[3,15,78,137],"PS2":[4],"integrins":[5],"are":[6,22,62,186],"required":[7,92],"to":[8,54,129,138,159,178,190],"maintain":[9],"the":[10,13,28,115,131,142,162,168,191],"connection":[11],"between":[12],"dorsal":[14],"ventral":[16],"wing":[17,33,60,103,172],"epithelia.":[18],"If":[19],"alphaPS":[20],"subunits":[21,71],"inappropriately":[23],"expressed":[24],"during":[25],"early":[26],"pupariation,":[27],"epithelia":[29],"separate,":[30],"causing":[31],"a":[32,47,109,119],"blister.":[34],"Two":[35],"lines":[36],"of":[37,57,68,102,108,122,145,156,171,180,194],"evidence":[38],"indicate":[39],"that":[40,74,167],"this":[41,150],"apparent":[42],"loss-of-function":[43,69],"phenotype":[44],"is":[45,52,174],"not":[46,63,175],"dominant":[48,100],"negative":[49],"effect,":[50],"but":[51],"due":[53],"inappropriate":[55],"expression":[56,87],"functional":[58],"integrins:":[59],"blisters":[61,104,173],"generated":[64,105],"efficiently":[65],"by":[66,93,197],"misexpression":[67],"alphaPS2":[70,82],"with":[72,149,188],"mutations":[73],"inhibit":[75],"ligand":[76],"binding,":[77],"gain-of-function,":[79],"hyperactivated":[80],"mutant":[81,154],"proteins":[83],"cause":[84],"blistering":[85],"at":[86],"levels":[88],"well":[89],"below":[90],"those":[91],"wild-type":[94],"proteins.":[95],"A":[96],"genetic":[97],"screen":[98],"for":[99],"suppressors":[101],"null":[106],"alleles":[107],"gene":[110],"named":[111],"moleskin,":[112],"which":[113],"encodes":[114],"protein":[116],"DIM-7.":[117],"DIM-7,":[118],"homolog":[121,135],"vertebrate":[123],"importin-7,":[124],"has":[125],"recently":[126],"been":[127],"shown":[128],"bind":[130],"SHP-2":[132],"tyrosine":[133],"phosphatase":[134],"Corkscrew":[136],"be":[139],"important":[140],"in":[141,161],"nuclear":[143,182],"translocation":[144],"activated":[146],"D-ERK.":[147],"Consistent":[148],"latter":[151],"finding,":[152],"homozygous":[153],"clones":[155],"moleskin":[157,169],"fail":[158],"grow":[160],"wing.":[163],"Genetic":[164],"tests":[165],"suggest":[166],"suppression":[170],"directly":[176],"related":[177],"inhibition":[179],"D-ERK":[181],"import.":[183],"These":[184],"data":[185],"discussed":[187],"respect":[189],"possible":[192],"regulation":[193],"integrin":[195],"function":[196],"cytoplasmic":[198],"ERK.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}