{"id":"https://openalex.org/W2123652015","doi":null,"title":"Spectrum of histological features in non-alcoholic fatty liver disease.","display_name":"Spectrum of histological features in non-alcoholic fatty liver disease.","publication_year":2007,"publication_date":"2007-11-01","ids":{"openalex":"https://openalex.org/W2123652015","mag":"2123652015","pmid":"https://pubmed.ncbi.nlm.nih.gov/18335793"},"language":"en","primary_location":{"id":"pmid:18335793","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18335793","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The National medical journal of India","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057026536","display_name":"Nandini Vasdev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113434","display_name":"Sir Ganga Ram Hospital","ror":"https://ror.org/01x18vk56","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210113434"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nandini Vasdev","raw_affiliation_strings":["Department of Histopathology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi 110060, India. minivasdev@rediffmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi 110060, India. minivasdev@rediffmail.com","institution_ids":["https://openalex.org/I4210113434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004084020","display_name":"Anjali G Kakati","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anjali G Kakati","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046706723","display_name":"Sanjiv Saigal","orcid":"https://orcid.org/0000-0001-5677-7140","observed_orcids":["https://orcid.org/0000-0001-5677-7140"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sanjiv Saigal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109179542","display_name":"Nabeen Chandra Nayak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nabeen C Nayak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6056,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.731638,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"20","issue":"6","first_page":"282","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":1.0},{"id":"https://openalex.org/keywords/liver-histopathology","display_name":"liver histopathology","score":0.7860000133514404},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.6129999756813049},{"id":"https://openalex.org/keywords/hepatocyte-injury","display_name":"hepatocyte injury","score":0.9739999771118164},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.8140000104904175},{"id":"https://openalex.org/keywords/histological-staging","display_name":"histological staging","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.950087308883667},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.7992390394210815},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6977344155311584},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.637557864189148},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5772130489349365},{"id":"https://openalex.org/C2777766500","wikidata":"https://www.wikidata.org/wiki/Q360841","display_name":"Liver biopsy","level":3,"score":0.5685842633247375},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5402886271476746},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4887516498565674},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4759623408317566},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.4362143874168396},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.40118664503097534},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.376987487077713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14193937182426453},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006509","descriptor_name":"Hepatitis B","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:18335793","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18335793","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The National medical journal of India","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.621.5492","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.621.5492","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nmji.in/archives/volume_20/number_6/pdf_20_6/original_article_1.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W72681161","https://openalex.org/W163213204","https://openalex.org/W1965538010","https://openalex.org/W1966559673","https://openalex.org/W1976173209","https://openalex.org/W1977036235","https://openalex.org/W1981900811","https://openalex.org/W1983417944","https://openalex.org/W1984340206","https://openalex.org/W2001837599","https://openalex.org/W2040109162","https://openalex.org/W2042555983","https://openalex.org/W2047499703","https://openalex.org/W2055260338","https://openalex.org/W2056728315","https://openalex.org/W2063671857","https://openalex.org/W2065575272","https://openalex.org/W2065788317","https://openalex.org/W2067740038","https://openalex.org/W2077344442","https://openalex.org/W2080348345","https://openalex.org/W2081411861","https://openalex.org/W2085766690","https://openalex.org/W2087829753","https://openalex.org/W2123650181","https://openalex.org/W2142844314","https://openalex.org/W2148028316","https://openalex.org/W2156792510","https://openalex.org/W2253667517","https://openalex.org/W2396586125","https://openalex.org/W2405846450"],"related_works":["https://openalex.org/W7096153990","https://openalex.org/W7151396920","https://openalex.org/W2576488295","https://openalex.org/W2134167042","https://openalex.org/W2034212495","https://openalex.org/W3095137054","https://openalex.org/W2034906546","https://openalex.org/W2182670456","https://openalex.org/W4309098910","https://openalex.org/W2060967475"],"abstract_inverted_index":{"BACKGROUND:":[0],"Non-alcoholic":[1],"fatty":[2,260],"liver":[3,23,75],"disease":[4],"(NAFLD)":[5],"has":[6],"become":[7],"an":[8],"Important":[9],"entity":[10],"globally,":[11],"including":[12],"in":[13,42,62,78,140,148,154,165,180,248],"India":[14],"and":[15,31,48,89,125,131,144,173,198,223,240,242,253],"other":[16,257],"Asian":[17],"countries.":[18],"Morphological":[19],"evaluation":[20],"of":[21,34,40,59,73,106,108,117,121,170,184,203,214,228,236,244,251,259],"a":[22,71,101,118,168],"biopsy":[24],"is":[25,216],"necessary":[26],"for":[27,127],"the":[28,38,43,57,115,149,171,234,237,249],"diagnosis,":[29],"staging":[30],"possibly":[32],"management":[33],"this":[35],"disease.":[36],"However,":[37],"spectrum":[39,58],"changes":[41],"liver,":[44],"their":[45],"evolution,":[46],"Interrelationships":[47],"implications":[49],"are":[50,246],"incompletely":[51],"understood.":[52],"We":[53],"aimed":[54],"to":[55,193],"study":[56,66],"histological":[60,99],"abnormalities":[61],"NAFLD.":[63],"METHODS:":[64],"The":[65,182],"material":[67],"was":[68,104,137,163,178],"drawn":[69],"from":[70,86,256],"pool":[72],"80":[74],"biopsies":[76],"diagnosed":[77],"our":[79,87],"laboratory":[80],"as":[81,111],"NAFLD,":[82],"67":[83],"retrieved":[84],"retrospectively":[85],"records":[88],"13":[90],"obtained":[91],"prospectively":[92],"with":[93,176,187,195,205,218],"complete":[94],"clinical":[95],"data.":[96],"After":[97],"comprehensive":[98],"assessment,":[100],"detailed":[102],"analysis":[103],"done":[105],"32":[107],"those":[109],"categorized":[110],"definitive":[112],"NAFLD":[113,206,252],"on":[114],"basis":[116],"dependable":[119],"history":[120],"no":[122],"alcohol":[123],"Intake":[124],"seronegativity":[126],"hepatitis":[128],"virus":[129],"B":[130],"C":[132],"Infections.":[133],"RESULTS:":[134],"Fatty":[135],"change":[136],"preferentially":[138],"seen":[139],"acinar":[141,224,229],"zones":[142],"2":[143,231],"3,":[145],"more":[146,166],"so":[147],"former.":[150],"Steatotic":[151],"cells":[152],"varied":[153],"size;":[155],"some":[156],"large":[157],"ones":[158],"were":[159],"non-spherical.":[160],"Steatosis":[161],"alone":[162],"present":[164,179],"than":[167],"quarter":[169],"cases":[172],"steatosis":[174,185,215],"along":[175],"inflammation":[177,245],"half.":[181],"magnitude":[183],"correlated":[186],"inflammation,":[188],"while":[189],"both":[190],"these":[191],"seemed":[192],"correlate":[194],"hepatocyte":[196,221],"Injury":[197],"fibrosis.":[199,225],"CONCLUSION:":[200],"A":[201],"proportion":[202],"patients":[204],"show":[207],"only":[208],"hepatic":[209],"steatosis.":[210],"An":[211],"Increasing":[212],"grade":[213],"associated":[217],"greater":[219],"Inflammation,":[220],"injury":[222],"Preferential":[226],"involvement":[227],"zone":[230],"by":[232],"steatosis,":[233],"morphology":[235],"steatotic":[238],"cells,":[239],"nature":[241],"location":[243],"important":[247],"diagnosis":[250],"its":[254],"differentiation":[255],"causes":[258],"liver.":[261]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}