{"id":"https://openalex.org/W2123257520","doi":"https://doi.org/10.1073/pnas.0704912104","title":"Biosynthesis of 2-methylbacteriohopanepolyols by an anoxygenic phototroph","display_name":"Biosynthesis of 2-methylbacteriohopanepolyols by an anoxygenic phototroph","publication_year":2007,"publication_date":"2007-09-11","ids":{"openalex":"https://openalex.org/W2123257520","doi":"https://doi.org/10.1073/pnas.0704912104","mag":"2123257520","pmid":"https://pubmed.ncbi.nlm.nih.gov/17848515","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1986619"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.0704912104","doi":"https://doi.org/10.1073/pnas.0704912104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0704912104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1986619","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090172460","display_name":"Sky Rashby","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sky E. Rashby","raw_affiliation_strings":["Divisions of *Geological and Planetary Sciences and","Divisions of Geological and Planetary Sciences and Biology, California Institute of Technology and Howard Hughes Medical Institute, Pasadena, CA 91125, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisions of *Geological and Planetary Sciences and","institution_ids":[]},{"raw_affiliation_string":"Divisions of Geological and Planetary Sciences and Biology, California Institute of Technology and Howard Hughes Medical Institute, Pasadena, CA 91125, USA","institution_ids":["https://openalex.org/I122411786","https://openalex.org/I1344073410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002863478","display_name":"Alex L. Sessions","orcid":"https://orcid.org/0000-0001-6120-2763","observed_orcids":["https://orcid.org/0000-0001-6120-2763"]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex L. Sessions","raw_affiliation_strings":["Divisions of *Geological and Planetary Sciences and","California  Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisions of *Geological and Planetary Sciences and","institution_ids":[]},{"raw_affiliation_string":"California  Institute of Technology","institution_ids":["https://openalex.org/I122411786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067547169","display_name":"Roger Everett Summons","orcid":"https://orcid.org/0000-0002-7144-8537","observed_orcids":["https://orcid.org/0000-0002-7144-8537"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roger E. Summons","raw_affiliation_strings":["Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065958736","display_name":"Dianne K. Newman","orcid":"https://orcid.org/0000-0003-1647-1918","observed_orcids":["https://orcid.org/0000-0003-1647-1918"]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dianne K. Newman","raw_affiliation_strings":["Biology, California Institute of Technology and","Divisions of *Geological and Planetary Sciences and","Howard Hughes Medical Institute, Pasadena, CA 91125; and","Massachusetts Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology, California Institute of Technology and","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"Divisions of *Geological and Planetary Sciences and","institution_ids":[]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Pasadena, CA 91125; and","institution_ids":["https://openalex.org/I1344073410"]},{"raw_affiliation_string":"Massachusetts Institute of Technology","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":12.5736,"has_fulltext":false,"cited_by_count":280,"citation_normalized_percentile":{"value":0.99452587,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"104","issue":"38","first_page":"15099","last_page":"15104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10109","display_name":"Paleontology and Stratigraphy of Fossils","score":0.5,"subfield":{"id":"https://openalex.org/subfields/1911","display_name":"Paleontology"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10109","display_name":"Paleontology and Stratigraphy of Fossils","score":0.5,"subfield":{"id":"https://openalex.org/subfields/1911","display_name":"Paleontology"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.06260000169277191,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10324","display_name":"Microbial bioremediation and biosurfactants","score":0.05469999834895134,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biosynthesis","display_name":"biosynthesis","score":0.722000002861023},{"id":"https://openalex.org/keywords/rhodopseudomonas-palustris","display_name":"Rhodopseudomonas palustris","score":0.9449999928474426},{"id":"https://openalex.org/keywords/anoxygenic-phototrophs","display_name":"anoxygenic phototrophs","score":0.9480000138282776},{"id":"https://openalex.org/keywords/bacteriohopanepolyols","display_name":"bacteriohopanepolyols","score":0.7419999837875366},{"id":"https://openalex.org/keywords/sedimentary-biomarkers","display_name":"sedimentary biomarkers","score":0.7310000061988831},{"id":"https://openalex.org/keywords/cyanobacteria","display_name":"cyanobacteria","score":0.6949999928474426},{"id":"https://openalex.org/keywords/methylation","display_name":"methylation","score":0.4429999887943268}],"concepts":[{"id":"https://openalex.org/C98614847","wikidata":"https://www.wikidata.org/wiki/Q975983","display_name":"Anoxygenic photosynthesis","level":4,"score":0.9935604333877563},{"id":"https://openalex.org/C197322856","wikidata":"https://www.wikidata.org/wiki/Q335183","display_name":"Phototroph","level":3,"score":0.8475285768508911},{"id":"https://openalex.org/C2779669040","wikidata":"https://www.wikidata.org/wiki/Q93315","display_name":"Cyanobacteria","level":3,"score":0.6632986068725586},{"id":"https://openalex.org/C2777444609","wikidata":"https://www.wikidata.org/wiki/Q2309799","display_name":"Chromatium","level":3,"score":0.5382314920425415},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5241318345069885},{"id":"https://openalex.org/C2778418169","wikidata":"https://www.wikidata.org/wiki/Q7321215","display_name":"Rhodopseudomonas palustris","level":3,"score":0.4541461169719696},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.44552624225616455},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34672728180885315},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.34132325649261475},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.32086849212646484},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2847566306591034},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.27706995606422424},{"id":"https://openalex.org/C183688256","wikidata":"https://www.wikidata.org/wiki/Q11982","display_name":"Photosynthesis","level":2,"score":0.2770262062549591},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.1150239109992981},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000332","descriptor_name":"Aerobiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002853","descriptor_name":"Chromatography, Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008401","descriptor_name":"Gas Chromatography-Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010788","descriptor_name":"Photosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012241","descriptor_name":"Rhodopseudomonas","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D012241","descriptor_name":"Rhodopseudomonas","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D052817","descriptor_name":"Phototrophic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.0704912104","doi":"https://doi.org/10.1073/pnas.0704912104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0704912104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1986619","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1986619","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:17848515","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17848515","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:authors.library.caltech.edu:9731","doi":null,"is_oa":false,"landing_page_url":"https://resolver.caltech.edu/CaltechAUTHORS:RASpnas07","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1986619","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1986619","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320332374","display_name":"Ames Research Center","ror":"https://ror.org/02acart68"},{"id":"https://openalex.org/F4320332564","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1433217890","https://openalex.org/W1482184946","https://openalex.org/W1519389355","https://openalex.org/W1528735038","https://openalex.org/W1532877896","https://openalex.org/W1607659620","https://openalex.org/W1630022358","https://openalex.org/W1910648731","https://openalex.org/W1971155442","https://openalex.org/W1971216336","https://openalex.org/W1974460286","https://openalex.org/W1976540634","https://openalex.org/W1978790450","https://openalex.org/W1984490456","https://openalex.org/W1987728700","https://openalex.org/W1988932644","https://openalex.org/W1989368374","https://openalex.org/W1993253748","https://openalex.org/W1995108967","https://openalex.org/W1996173391","https://openalex.org/W2005346644","https://openalex.org/W2005353275","https://openalex.org/W2018256378","https://openalex.org/W2018669887","https://openalex.org/W2024716965","https://openalex.org/W2029870606","https://openalex.org/W2032247127","https://openalex.org/W2035176528","https://openalex.org/W2044098658","https://openalex.org/W2044172259","https://openalex.org/W2047250677","https://openalex.org/W2067099347","https://openalex.org/W2074041658","https://openalex.org/W2080145647","https://openalex.org/W2081154408","https://openalex.org/W2085199314","https://openalex.org/W2087343508","https://openalex.org/W2101760406","https://openalex.org/W2116210675","https://openalex.org/W2134026320","https://openalex.org/W2143567572","https://openalex.org/W2145127588","https://openalex.org/W2145989765","https://openalex.org/W2147032286","https://openalex.org/W2148162388","https://openalex.org/W2156244175","https://openalex.org/W2159620478","https://openalex.org/W2159876209","https://openalex.org/W2160604050","https://openalex.org/W2172057173","https://openalex.org/W4233537042"],"related_works":["https://openalex.org/W2023959899","https://openalex.org/W4206465347","https://openalex.org/W2097291067","https://openalex.org/W2098095729","https://openalex.org/W3186091518","https://openalex.org/W3173292804","https://openalex.org/W2119851102","https://openalex.org/W3184714800","https://openalex.org/W1532877896","https://openalex.org/W6889803109"],"abstract_inverted_index":{"Sedimentary":[0],"2-methyhopanes":[1],"have":[2],"been":[3],"used":[4],"as":[5],"biomarker":[6],"proxies":[7],"for":[8],"cyanobacteria,":[9],"the":[10,20,36,47,58,63,96,122],"only":[11,21],"known":[12],"bacterial":[13],"clade":[14],"capable":[15,115],"of":[16,23,38,41,46,53,60,72,82,89,92,98,105,116,125],"oxygenic":[17],"photosynthesis":[18],"and":[19,119],"group":[22,66],"organisms":[24],"found":[25],"thus":[26],"far":[27],"to":[28,86],"produce":[29],"abundant":[30],"2-methylbacteriohopanepolyols":[31],"(2-MeBHPs).":[32],"Here,":[33],"we":[34],"report":[35],"identification":[37],"significant":[39],"quantities":[40],"2-MeBHP":[42,54,73],"in":[43,57],"two":[44],"strains":[45],"anoxygenic":[48,112],"phototroph":[49],"Rhodopseudomonas":[50],"palustris.":[51],"Biosynthesis":[52],"can":[55],"occur":[56],"absence":[59],"O(2),":[61],"deriving":[62],"C-2":[64],"methyl":[65],"from":[67,80],"methionine.":[68],"The":[69],"relative":[70],"abundance":[71],"varies":[74],"considerably":[75],"with":[76],"culture":[77],"conditions,":[78],"ranging":[79],"13.3%":[81],"total":[83],"bacteriohopanepolyol":[84],"(BHP)":[85],"trace":[87],"levels":[88],"methylation.":[90],"Analysis":[91],"intact":[93],"BHPs":[94],"reveals":[95],"presence":[97],"methylated":[99],"bacteriohopane-32,33,34,35-tetrol":[100],"but":[101],"no":[102],"detectable":[103],"methylation":[104],"35-aminobacteriohopane-32,33,34-triol.":[106],"Our":[107],"results":[108],"demonstrate":[109],"that":[110,121],"an":[111],"photoautotroph":[113],"is":[114],"generating":[117],"2-MeBHPs":[118],"show":[120],"potential":[123],"origins":[124],"sedimentary":[126],"2-methylhopanoids":[127],"are":[128],"more":[129],"diverse":[130],"than":[131],"previously":[132],"thought.":[133]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":16},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":16},{"year":2014,"cited_by_count":21},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":23}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}