{"id":"https://openalex.org/W2122607752","doi":"https://doi.org/10.1152/ajpendo.1999.277.1.e49","title":"Inhibition of salmon calcitonin on secretion of progesterone and GnRH-stimulated pituitary luteinizing hormone","display_name":"Inhibition of salmon calcitonin on secretion of progesterone and GnRH-stimulated pituitary luteinizing hormone","publication_year":1999,"publication_date":"1999-07-01","ids":{"openalex":"https://openalex.org/W2122607752","doi":"https://doi.org/10.1152/ajpendo.1999.277.1.e49","mag":"2122607752","pmid":"https://pubmed.ncbi.nlm.nih.gov/10409127"},"language":"en","primary_location":{"id":"doi:10.1152/ajpendo.1999.277.1.e49","doi":"https://doi.org/10.1152/ajpendo.1999.277.1.e49","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpendo.1999.277.1.e49","pdf_url":null,"source":{"id":"https://openalex.org/S196637695","display_name":"American Journal of Physiology-Endocrinology and Metabolism","issn_l":"0193-1849","issn":["0193-1849","1522-1555"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Endocrinology and Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100831141","display_name":"Shiow-Chwen Tsai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shiow-Chwen Tsai","raw_affiliation_strings":["Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chien-Chen Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chien-Chen Lu","raw_affiliation_strings":["Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111927010","display_name":"Jiann-Jong Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jiann-Jong Chen","raw_affiliation_strings":["Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028534824","display_name":"Yu\u2010Chung Chiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu-Chung Chiao","raw_affiliation_strings":["Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050104295","display_name":"Shyi\u2010Wu Wang","orcid":"https://orcid.org/0000-0001-9392-3530","observed_orcids":["https://orcid.org/0000-0001-9392-3530"]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shyi-Wu Wang","raw_affiliation_strings":["Department of Physiology, College of Medicine, Chang-Gung University, Taoyuan 33333, Taiwan, Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, College of Medicine, Chang-Gung University, Taoyuan 33333, Taiwan, Republic of China","institution_ids":["https://openalex.org/I173093425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112904402","display_name":"Jiuan-Jiuan Hwang","orcid":"https://orcid.org/0000-0003-1191-9795","observed_orcids":["https://orcid.org/0000-0003-1191-9795"]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jiuan-Jiuan Hwang","raw_affiliation_strings":["Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032170703","display_name":"Paulus S. Wang","orcid":"https://orcid.org/0000-0002-2917-0930","observed_orcids":["https://orcid.org/0000-0002-2917-0930"]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Paulus S. Wang","raw_affiliation_strings":["Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Schools of Medicine and Life Science, National Yang-Ming University, Taipei 11221; and","institution_ids":["https://openalex.org/I4387156312"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6262,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.60748733,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"277","issue":"1","first_page":"E49","last_page":"E55"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.012799999676644802,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salmon-calcitonin","display_name":"salmon calcitonin","score":1.0},{"id":"https://openalex.org/keywords/progesterone-synthesis","display_name":"progesterone secretion","score":0.8569999933242798},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.9610000252723694},{"id":"https://openalex.org/keywords/gonadotropin-releasing-hormone","display_name":"gonadotropin-releasing hormone","score":0.5839999914169312},{"id":"https://openalex.org/keywords/anterior-pituitary","display_name":"anterior pituitary","score":0.8650000095367432},{"id":"https://openalex.org/keywords/granulosa-cells","display_name":"granulosa cells","score":0.9380000233650208},{"id":"https://openalex.org/keywords/ovariectomy","display_name":"ovariectomy","score":0.5709999799728394},{"id":"https://openalex.org/keywords/human-chorionic-gonadotropin","display_name":"human chorionic gonadotropin","score":0.8840000033378601},{"id":"https://openalex.org/keywords/camp-signaling","display_name":"cAMP signaling","score":0.7070000171661377},{"id":"https://openalex.org/keywords/steroidogenesis","display_name":"steroidogenesis","score":0.7369999885559082},{"id":"https://openalex.org/keywords/25-hydroxycholesterol","display_name":"25-hydroxycholesterol","score":0.8740000128746033},{"id":"https://openalex.org/keywords/pregnenolone","display_name":"pregnenolone","score":0.968999981880188},{"id":"https://openalex.org/keywords/gonadotropin-suppression","display_name":"gonadotropin suppression","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.9108060002326965},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8965630531311035},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.6532675623893738},{"id":"https://openalex.org/C8264082","wikidata":"https://www.wikidata.org/wiki/Q7113259","display_name":"Ovariectomized rat","level":3,"score":0.5491200089454651},{"id":"https://openalex.org/C2775948956","wikidata":"https://www.wikidata.org/wiki/Q407172","display_name":"Human chorionic gonadotropin","level":3,"score":0.5428982973098755},{"id":"https://openalex.org/C2778782382","wikidata":"https://www.wikidata.org/wiki/Q409770","display_name":"Gonadotropin","level":3,"score":0.4900904893875122},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45847088098526},{"id":"https://openalex.org/C2779627488","wikidata":"https://www.wikidata.org/wiki/Q315860","display_name":"Calcitonin","level":2,"score":0.4480752944946289},{"id":"https://openalex.org/C2779029589","wikidata":"https://www.wikidata.org/wiki/Q356002","display_name":"Anterior pituitary","level":3,"score":0.41851192712783813},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4098222553730011},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3289092779159546},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2508265972137451}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002116","descriptor_name":"Calcitonin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002786","descriptor_name":"Cholesterol Side-Chain Cleavage Enzyme","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006063","descriptor_name":"Chorionic Gonadotropin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006107","descriptor_name":"Granulosa Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006107","descriptor_name":"Granulosa Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007986","descriptor_name":"Luteinizing Hormone","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D007986","descriptor_name":"Luteinizing Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007986","descriptor_name":"Luteinizing Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007987","descriptor_name":"Gonadotropin-Releasing Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010902","descriptor_name":"Pituitary Gland","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011374","descriptor_name":"Progesterone","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D011374","descriptor_name":"Progesterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011374","descriptor_name":"Progesterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015096","descriptor_name":"3-Hydroxysteroid Dehydrogenases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpendo.1999.277.1.e49","doi":"https://doi.org/10.1152/ajpendo.1999.277.1.e49","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpendo.1999.277.1.e49","pdf_url":null,"source":{"id":"https://openalex.org/S196637695","display_name":"American Journal of Physiology-Endocrinology and Metabolism","issn_l":"0193-1849","issn":["0193-1849","1522-1555"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Endocrinology and Metabolism","raw_type":"journal-article"},{"id":"pmid:10409127","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10409127","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1484404766","https://openalex.org/W1775749144","https://openalex.org/W1965655315","https://openalex.org/W1967311636","https://openalex.org/W1971086779","https://openalex.org/W1975712371","https://openalex.org/W1977869122","https://openalex.org/W1978597883","https://openalex.org/W1979636011","https://openalex.org/W1982059531","https://openalex.org/W1984585262","https://openalex.org/W1985257301","https://openalex.org/W1988418183","https://openalex.org/W1988966475","https://openalex.org/W1990068934","https://openalex.org/W1992897439","https://openalex.org/W1998843669","https://openalex.org/W2000068285","https://openalex.org/W2001120190","https://openalex.org/W2001289439","https://openalex.org/W2014227418","https://openalex.org/W2020240345","https://openalex.org/W2028433795","https://openalex.org/W2028466678","https://openalex.org/W2036377185","https://openalex.org/W2040067193","https://openalex.org/W2043610823","https://openalex.org/W2044553936","https://openalex.org/W2049433638","https://openalex.org/W2052329395","https://openalex.org/W2052385273","https://openalex.org/W2054394353","https://openalex.org/W2063597536","https://openalex.org/W2067813556","https://openalex.org/W2071038766","https://openalex.org/W2090675349","https://openalex.org/W2100508933","https://openalex.org/W2103225428","https://openalex.org/W2103537730","https://openalex.org/W2105840840","https://openalex.org/W2113279630","https://openalex.org/W2118863372","https://openalex.org/W2160536095","https://openalex.org/W2177315971","https://openalex.org/W2277592950","https://openalex.org/W2344752060"],"related_works":["https://openalex.org/W2917092362","https://openalex.org/W2000068285","https://openalex.org/W2100508933","https://openalex.org/W2153799215","https://openalex.org/W2023912961","https://openalex.org/W2030438582","https://openalex.org/W2093802761","https://openalex.org/W2110036893","https://openalex.org/W7099591236","https://openalex.org/W2045155965"],"abstract_inverted_index":{"The":[0],"effects":[1,128],"of":[2,9,13,68,77,104,113,117,129,137,143,166,185],"salmon":[3],"calcitonin":[4],"(sCT)":[5],"on":[6,168,177],"the":[7,48,62,80,101,110,126,163,183],"production":[8,96,123,158],"progesterone":[10,84,95,122,157],"and":[11,54,82,88,119,124,174,188],"secretion":[12],"luteinizing":[14],"hormone":[15,147],"(LH)":[16],"were":[17,24,41,59,71],"examined":[18],"in":[19,49,86,89,159,171],"female":[20],"rats.":[21],"Diestrous":[22],"rats":[23,40,70,160],"intravenously":[25],"injected":[26,42],"with":[27,43,61],"saline,":[28],"sCT,":[29],"human":[30],"chorionic":[31],"gonadotropin":[32],"(hCG),":[33],"or":[34,45],"hCG":[35],"plus":[36],"sCT.":[37,46,105,114,130],"Ovariectomized":[38],"(Ovx)":[39],"saline":[44],"In":[47],"vitro":[50],"experiments,":[51],"granulosa":[52,179],"cells":[53,180],"anterior":[55],"pituitary":[56],"glands":[57],"(APs)":[58],"incubated":[60],"tested":[63],"drugs.":[64],"Plasma":[65],"LH":[66,138,149,169],"levels":[67],"Ovx":[69],"reduced":[72],"by":[73,139,161],"sCT":[74,78,131,144,155],"injection.":[75],"Administration":[76],"decreased":[79,145],"basal":[81,135],"hCG-stimulated":[83],"release":[85,136,170],"vivo":[87],"vitro.":[90],"8-Bromo-cAMP":[91],"dose":[92],"dependently":[93],"increased":[94],"but":[97,141],"did":[98,107,132],"not":[99,108,133],"alter":[100],"inhibitory":[102,111,127],"effect":[103,112,165],"H-89":[106],"potentiate":[109],"Higher":[115],"doses":[116],"25-hydroxycholesterol":[118],"pregnenolone":[120],"stimulated":[121],"diminished":[125],"decrease":[134,182],"APs,":[140],"pretreatment":[142],"gonadotropin-releasing":[146],"(GnRH)-stimulated":[148],"secretion.":[150],"These":[151],"results":[152],"suggested":[153],"that":[154],"inhibits":[156],"preventing":[162],"stimulatory":[164],"GnRH":[167],"rat":[172],"APs":[173],"acting":[175],"directly":[176],"ovarian":[178],"to":[181],"activities":[184],"post-cAMP":[186],"pathway":[187],"steroidogenic":[189],"enzymes.":[190]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}