{"id":"https://openalex.org/W2122230549","doi":null,"title":"Associated Markers for Adult-onset Allergic Asthma.","display_name":"Associated Markers for Adult-onset Allergic Asthma.","publication_year":2015,"publication_date":"2015-10-01","ids":{"openalex":"https://openalex.org/W2122230549","mag":"2122230549","pmid":"https://pubmed.ncbi.nlm.nih.gov/26742445"},"language":"en","primary_location":{"id":"pmid:26742445","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26742445","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian journal of allergy, asthma, and immunology","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043186056","display_name":"Mart\u00edn Bedolla\u2010Barajas","orcid":"https://orcid.org/0000-0003-4915-1582","observed_orcids":["https://orcid.org/0000-0003-4915-1582"]},"institutions":[{"id":"https://openalex.org/I4210120508","display_name":"Hospital Civil de Guadalajara","ror":"https://ror.org/02epdjj68","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210120508"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Mart\u00edn Bedolla-Barajas","raw_affiliation_strings":["Allergy and Clinical Immunology Service, Division of Internal Medicine, Hospital Civil de Guadalajara \"Dr. Juan I. Menchaca\", Guadalajara, Jalisco, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergy and Clinical Immunology Service, Division of Internal Medicine, Hospital Civil de Guadalajara \"Dr. Juan I. Menchaca\", Guadalajara, Jalisco, Mexico","institution_ids":["https://openalex.org/I4210120508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054998006","display_name":"Jaime Morales\u2010Romero","orcid":"https://orcid.org/0000-0002-1492-1797","observed_orcids":["https://orcid.org/0000-0002-1492-1797"]},"institutions":[{"id":"https://openalex.org/I147280213","display_name":"Universidad Veracruzana","ror":"https://ror.org/03efxn362","country_code":"MX","type":"education","lineage":["https://openalex.org/I147280213"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Jaime Morales-Romero","raw_affiliation_strings":["Instituto de Salud P\u00fablica, Universidad Veracruzana, Xalapa,Veracruz, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Salud P\u00fablica, Universidad Veracruzana, Xalapa,Veracruz, Mexico","institution_ids":["https://openalex.org/I147280213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034242698","display_name":"Tonatiuh Ramses Bedolla-Pulido","orcid":"https://orcid.org/0000-0002-5292-0728","observed_orcids":["https://orcid.org/0000-0002-5292-0728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tonatiuh Ramses-Bedolla-Pulido","raw_affiliation_strings":["Universidad Guadalajara Lamar, Guadalajara, Jalisco, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad Guadalajara Lamar, Guadalajara, Jalisco, Mexico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064878280","display_name":"Lourdes Fabiola Garc\u00eda-Padilla","orcid":"https://orcid.org/0000-0001-8513-1613","observed_orcids":["https://orcid.org/0000-0001-8513-1613"]},"institutions":[{"id":"https://openalex.org/I193181351","display_name":"Universidad de Guadalajara","ror":"https://ror.org/043xj7k26","country_code":"MX","type":"education","lineage":["https://openalex.org/I193181351"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Lourdes Fabiola-Garc\u00eda-Padilla","raw_affiliation_strings":["Medical Doctor. Universidad de Guadalajara, Guadalajara, Jalisco, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Doctor. Universidad de Guadalajara, Guadalajara, Jalisco, Mexico","institution_ids":["https://openalex.org/I193181351"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014273246","display_name":"Dante Daniel Hern\u00e1ndez-Col\u00edn","orcid":"https://orcid.org/0000-0002-2424-9455","observed_orcids":["https://orcid.org/0000-0002-2424-9455"]},"institutions":[{"id":"https://openalex.org/I4210120508","display_name":"Hospital Civil de Guadalajara","ror":"https://ror.org/02epdjj68","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210120508"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Dante Hern\u00e1ndez-Col\u00edn","raw_affiliation_strings":["Head of Research, Hospital Civil de Guadalajara \"Dr. Juan I. Menchaca\", Guadalajara, Jalisco, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Head of Research, Hospital Civil de Guadalajara \"Dr. Juan I. Menchaca\", Guadalajara, Jalisco, Mexico","institution_ids":["https://openalex.org/I4210120508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.11251682,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"14","issue":"5","first_page":"545","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adult-onset-asthma","display_name":"adult-onset asthma","score":0.9879999756813049},{"id":"https://openalex.org/keywords/allergic-asthma","display_name":"allergic asthma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/age-at-asthma-onset","display_name":"age at asthma onset","score":0.8420000076293945},{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.8029999732971191},{"id":"https://openalex.org/keywords/serum-ige","display_name":"serum IgE","score":0.8519999980926514},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8399999737739563},{"id":"https://openalex.org/keywords/aeroallergen-sensitization","display_name":"aeroallergen sensitization","score":0.9319999814033508},{"id":"https://openalex.org/keywords/eosinophil-count","display_name":"eosinophil count","score":0.9599999785423279},{"id":"https://openalex.org/keywords/asthma-severity","display_name":"asthma severity","score":0.7919999957084656},{"id":"https://openalex.org/keywords/asthma-control","display_name":"asthma control","score":0.9279999732971191}],"concepts":[{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.9073699116706848},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8881624937057495},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.6849305629730225},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6831541061401367},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.6596025824546814},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6565068960189819},{"id":"https://openalex.org/C2778391694","wikidata":"https://www.wikidata.org/wiki/Q4688176","display_name":"Aeroallergen","level":4,"score":0.5522947311401367},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.508527398109436},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4826970100402832},{"id":"https://openalex.org/C2776217527","wikidata":"https://www.wikidata.org/wiki/Q944828","display_name":"Sensitization","level":2,"score":0.4695141017436981},{"id":"https://openalex.org/C2777767895","wikidata":"https://www.wikidata.org/wiki/Q4691924","display_name":"Age of onset","level":3,"score":0.43711498379707336},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.4368470311164856},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4224834740161896},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.16139885783195496},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.058608055114746094},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004342","descriptor_name":"Drug Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004342","descriptor_name":"Drug Hypersensitivity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004802","descriptor_name":"Eosinophilia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004802","descriptor_name":"Eosinophilia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005512","descriptor_name":"Food Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005512","descriptor_name":"Food Hypersensitivity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005541","descriptor_name":"Forced Expiratory Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008800","descriptor_name":"Mexico","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013147","descriptor_name":"Spirometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014797","descriptor_name":"Vital Capacity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050177","descriptor_name":"Overweight","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:26742445","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26742445","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian journal of allergy, asthma, and immunology","raw_type":"Comparative Study"},{"id":"pmh:oai:doaj.org/article:46a3cc7337784779b64dc9cedd0c0d56","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/46a3cc7337784779b64dc9cedd0c0d56","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Iranian Journal of Allergy, Asthma and Immunology, Vol 14, Iss 5 (2015)","raw_type":"article"},{"id":"mag:2122230549","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26742445","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W387031605","https://openalex.org/W1546095906","https://openalex.org/W1572652448","https://openalex.org/W1595045481","https://openalex.org/W1715557286","https://openalex.org/W1969976800","https://openalex.org/W1974903588","https://openalex.org/W1975373828","https://openalex.org/W1992245040","https://openalex.org/W1998653620","https://openalex.org/W2010929619","https://openalex.org/W2012434022","https://openalex.org/W2018509342","https://openalex.org/W2019840426","https://openalex.org/W2037845801","https://openalex.org/W2049663505","https://openalex.org/W2062484680","https://openalex.org/W2089383541","https://openalex.org/W2091103627","https://openalex.org/W2101036849","https://openalex.org/W2125078269","https://openalex.org/W2137070647","https://openalex.org/W2143053029","https://openalex.org/W2150035260","https://openalex.org/W2165580851","https://openalex.org/W2616424562"],"related_works":["https://openalex.org/W2902595296","https://openalex.org/W2312975841","https://openalex.org/W4388812513","https://openalex.org/W1330418","https://openalex.org/W4387980147","https://openalex.org/W4387736432","https://openalex.org/W4312710053","https://openalex.org/W4383186758","https://openalex.org/W4406810426","https://openalex.org/W2143495174"],"abstract_inverted_index":{"The":[0],"clinical":[1,52],"behavior":[2],"of":[3,18,51],"asthma":[4,21,33,66,70,75,112,144,174],"varies":[5],"with":[6,32,40,111,143],"age":[7],"at":[8,35,42,73],"onset.":[9],"This":[10],"study":[11,26],"was":[12,94,108,175],"undertaken":[13],"to":[14,127,158,168],"identify":[15],"associated":[16,110],"markers":[17],"adult-onset":[19],"allergic":[20,134,173],"(age":[22],"\u226520":[23,36,43,90,115,147],"years).This":[24],"cross-sectional":[25],"compared":[27,47],"two":[28],"groups:":[29],"58":[30],"patients":[31],"onset":[34,41,113,145],"years":[37,116,148],"and":[38,54,69,81,89,136,162],"66":[39],"years.":[44],"They":[45],"were":[46,77,140],"depending":[48],"on":[49],"results":[50],"history,":[53],"body":[55],"mass":[56],"index":[57],"(BMI),":[58],"aeroallergen":[59],"sensitization,":[60],"total":[61],"serum":[62],"IgE,":[63],"eosinophil":[64],"count,":[65],"control":[67],"test,":[68],"severity":[71],"level.Ages":[72],"first":[74],"episode":[76],"10.0":[78],"\u00b1":[79,83],"6.6":[80],"33.4":[82],"10.5":[84],"(p<0.001)":[85],"in":[86,96,114,146],"the":[87],"<20":[88],"group,":[91],"respectively.":[92],"BMI":[93,105],"higher":[95],"adult":[97],"asthmatic":[98],"subjects":[99],"(29.8":[100],"versus":[101],"27.1,":[102],"P=0.017),":[103],"but":[104],"\u226530":[106],"kg/m(2)":[107],"not":[109,176],"(odds":[117],"ratio":[118],"[OR]":[119],"=":[120,153],"1.56,":[121],"95%":[122,155,165],"confidence":[123],"interval":[124],"[CI]":[125],"0.759":[126],"3.211;":[128],"p=":[129,170],"0.227).":[130],"After":[131],"multivariate":[132],"analysis,":[133],"rhinitis":[135],"IgE":[137],"\u2265150":[138],"IU/mL":[139],"negatively":[141],"correlated":[142],"old":[149],"(OR":[150],"adjusted":[151],"[ORa]":[152],"0.255,":[154],"CI":[156,166],"0.078":[157],"0.837,":[159],"P=":[160],"0.024,":[161],"ORa":[163],"=0.385,":[164],"0.175":[167],"0.849,":[169],"0.018,":[171],"respectively).Adult-onset":[172],"different":[177],"from":[178],"early-onset":[179],"asthma.":[180]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}