{"id":"https://openalex.org/W2122003181","doi":"https://doi.org/10.1006/jmcc.1999.1098","title":"Palmitate-mediated Alterations in the Fatty Acid Metabolism of Rat Neonatal Cardiac Myocytes","display_name":"Palmitate-mediated Alterations in the Fatty Acid Metabolism of Rat Neonatal Cardiac Myocytes","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2122003181","doi":"https://doi.org/10.1006/jmcc.1999.1098","mag":"2122003181","pmid":"https://pubmed.ncbi.nlm.nih.gov/10731449"},"language":"en","primary_location":{"id":"doi:10.1006/jmcc.1999.1098","doi":"https://doi.org/10.1006/jmcc.1999.1098","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jmcc.1999.1098","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2122003181"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008104246","display_name":"Diane L. M. Hickson-Bick","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diane L.M Hickson-Bick","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030-1503, USA. diane.l.bick@uth.tmc.edu","Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030-1503, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030-1503, USA. diane.l.bick@uth.tmc.edu","institution_ids":[]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030-1503, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038526875","display_name":"Louis Maximilian Buja","orcid":"https://orcid.org/0000-0001-8386-7029","observed_orcids":["https://orcid.org/0000-0001-8386-7029"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maximilian L Buja","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas, 77030-1503, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas, 77030-1503, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109161175","display_name":"Jeanie B. McMillin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeanie B McMillin","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas, 77030-1503, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas, 77030-1503, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4120,"currency":"USD","value_usd":4120},"apc_paid":null,"fwci":4.8398,"has_fulltext":false,"cited_by_count":172,"citation_normalized_percentile":{"value":0.95317524,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"32","issue":"3","first_page":"511","last_page":"519"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.7407000064849854,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.7407000064849854,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.04320000112056732,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.041099999099969864,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/palmitate","display_name":"palmitate","score":0.9810000061988831},{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.8629999756813049},{"id":"https://openalex.org/keywords/neonatal-cardiomyocytes","display_name":"neonatal cardiomyocytes","score":0.9160000085830688},{"id":"https://openalex.org/keywords/malonyl-coa","display_name":"malonyl-CoA","score":0.8450000286102295},{"id":"https://openalex.org/keywords/ampk","display_name":"AMPK","score":0.9909999966621399},{"id":"https://openalex.org/keywords/ceramide","display_name":"ceramide","score":0.8930000066757202},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9739999771118164},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.9879999756813049},{"id":"https://openalex.org/keywords/oleate","display_name":"oleate","score":0.8429999947547913},{"id":"https://openalex.org/keywords/myocardial-ischemia-reperfusion-injury","display_name":"myocardial ischemia-reperfusion injury","score":0.8420000076293945},{"id":"https://openalex.org/keywords/substrate-utilization","display_name":"substrate utilization","score":0.609000027179718},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.6420000195503235},{"id":"https://openalex.org/keywords/programmed-cell-death","display_name":"programmed cell death","score":0.7440000176429749}],"concepts":[{"id":"https://openalex.org/C2777851122","wikidata":"https://www.wikidata.org/wiki/Q424213","display_name":"Ceramide","level":3,"score":0.7595030069351196},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.715908944606781},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7066043615341187},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6489092707633972},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5343970656394958},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.5133649706840515},{"id":"https://openalex.org/C155878803","wikidata":"https://www.wikidata.org/wiki/Q5205755","display_name":"DNA laddering","level":5,"score":0.497602254152298},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.4848378896713257},{"id":"https://openalex.org/C2780124434","wikidata":"https://www.wikidata.org/wiki/Q12357464","display_name":"AMPK","level":4,"score":0.46721377968788147},{"id":"https://openalex.org/C82714985","wikidata":"https://www.wikidata.org/wiki/Q306213","display_name":"Beta oxidation","level":3,"score":0.4267590045928955},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3860677182674408},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.3813683092594147},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38092491030693054},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.3611297607421875},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.35545453429222107},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3156434893608093},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.26747187972068787},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1354595124721527},{"id":"https://openalex.org/C43759708","wikidata":"https://www.wikidata.org/wiki/Q3749256","display_name":"DNA fragmentation","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002518","descriptor_name":"Ceramides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008316","descriptor_name":"Malonyl Coenzyme A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009097","descriptor_name":"Multienzyme Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010168","descriptor_name":"Palmitates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010168","descriptor_name":"Palmitates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017346","descriptor_name":"Protein Serine-Threonine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020169","descriptor_name":"Caspases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053148","descriptor_name":"Caspase 3","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055372","descriptor_name":"AMP-Activated Protein Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/jmcc.1999.1098","doi":"https://doi.org/10.1006/jmcc.1999.1098","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jmcc.1999.1098","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},{"id":"pmid:10731449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10731449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular and cellular cardiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3337415924","display_name":"FATTY ACID METABOLISM IN CARDIAC ISCHEMIA","funder_award_id":"R01HL038863","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W89491989","https://openalex.org/W151451480","https://openalex.org/W1483582878","https://openalex.org/W1503255196","https://openalex.org/W1522459970","https://openalex.org/W1909616616","https://openalex.org/W1945253873","https://openalex.org/W1967600689","https://openalex.org/W1970468997","https://openalex.org/W1972877540","https://openalex.org/W1974747981","https://openalex.org/W1978205295","https://openalex.org/W1979945873","https://openalex.org/W1990805315","https://openalex.org/W2002564316","https://openalex.org/W2033767220","https://openalex.org/W2033823674","https://openalex.org/W2034110828","https://openalex.org/W2039167216","https://openalex.org/W2047240368","https://openalex.org/W2058516725","https://openalex.org/W2063094444","https://openalex.org/W2070565811","https://openalex.org/W2079028801","https://openalex.org/W2083658751","https://openalex.org/W2086617396","https://openalex.org/W2089031022","https://openalex.org/W2124753768","https://openalex.org/W2128821991","https://openalex.org/W2140992882","https://openalex.org/W2142930789","https://openalex.org/W2154551468","https://openalex.org/W2158631571","https://openalex.org/W2159000141","https://openalex.org/W2169980195","https://openalex.org/W2252419928","https://openalex.org/W2268138861","https://openalex.org/W2270264925","https://openalex.org/W2407618083","https://openalex.org/W4244779685","https://openalex.org/W4246778745","https://openalex.org/W4323238414"],"related_works":["https://openalex.org/W2526962332","https://openalex.org/W1965718896","https://openalex.org/W2116287353","https://openalex.org/W2352653826","https://openalex.org/W1967478755","https://openalex.org/W2041836907","https://openalex.org/W2000601548","https://openalex.org/W2144007812","https://openalex.org/W2887126981","https://openalex.org/W115127599"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}