{"id":"https://openalex.org/W2121448433","doi":"https://doi.org/10.1128/mcb.6.7.2602","title":"Analysis of histone gene expression in adult tissues of the sea urchins Strongylocentrotus purpuratus and Lytechinus pictus: tissue-specific expression of sperm histone genes.","display_name":"Analysis of histone gene expression in adult tissues of the sea urchins Strongylocentrotus purpuratus and Lytechinus pictus: tissue-specific expression of sperm histone genes.","publication_year":1986,"publication_date":"1986-07-01","ids":{"openalex":"https://openalex.org/W2121448433","doi":"https://doi.org/10.1128/mcb.6.7.2602","mag":"2121448433","pmid":"https://pubmed.ncbi.nlm.nih.gov/3785204","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/367816"},"language":"en","primary_location":{"id":"doi:10.1128/mcb.6.7.2602","doi":"https://doi.org/10.1128/mcb.6.7.2602","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.6.7.2602","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/367816","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045836677","display_name":"Toby Lieber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T Lieber","raw_affiliation_strings":["Departments of Genetics and Molecular Biology, Albert Einstein College of MeXlicine, Bronx, New York 10461"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Genetics and Molecular Biology, Albert Einstein College of MeXlicine, Bronx, New York 10461","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087292020","display_name":"Karen E. Weisser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K Weisser","raw_affiliation_strings":["Departments of Genetics and Molecular Biology, Albert Einstein College of MeXlicine, Bronx, New York 10461"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Genetics and Molecular Biology, Albert Einstein College of MeXlicine, Bronx, New York 10461","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044237462","display_name":"Geoffrey J. Childs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G Childs","raw_affiliation_strings":["Departments of Genetics and Molecular Biology, Albert Einstein College of MeXlicine, Bronx, New York 10461"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Genetics and Molecular Biology, Albert Einstein College of MeXlicine, Bronx, New York 10461","institution_ids":["https://openalex.org/I129975664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I129975664"],"apc_list":null,"apc_paid":null,"fwci":3.4546,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.93733255,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"7","first_page":"2602","last_page":"2612"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histone-gene-expression","display_name":"histone gene expression","score":0.9490000009536743},{"id":"https://openalex.org/keywords/histone-h1","display_name":"histone H1","score":0.8059999942779541},{"id":"https://openalex.org/keywords/histone-h2b","display_name":"histone H2B","score":0.9869999885559082},{"id":"https://openalex.org/keywords/tissue-specific-expression","display_name":"tissue-specific gene expression","score":0.8349999785423279},{"id":"https://openalex.org/keywords/strongylocentrotus-purpuratus","display_name":"Strongylocentrotus purpuratus","score":0.953000009059906},{"id":"https://openalex.org/keywords/lytechinus-pictus","display_name":"Lytechinus pictus","score":1.0},{"id":"https://openalex.org/keywords/sea-urchins","display_name":"sea urchins","score":0.7300000190734863},{"id":"https://openalex.org/keywords/cdna-clones","display_name":"cDNA clones","score":0.6710000038146973}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9555914402008057},{"id":"https://openalex.org/C2777569064","wikidata":"https://www.wikidata.org/wiki/Q1936405","display_name":"Strongylocentrotus purpuratus","level":3,"score":0.8828719854354858},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.5832624435424805},{"id":"https://openalex.org/C2776908312","wikidata":"https://www.wikidata.org/wiki/Q83483","display_name":"Sea urchin","level":2,"score":0.5706383585929871},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48012566566467285},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.45394495129585266},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3762195110321045},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3538356423377991},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3478977084159851}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012617","descriptor_name":"Sea Urchins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/mcb.6.7.2602","doi":"https://doi.org/10.1128/mcb.6.7.2602","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.6.7.2602","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1293536","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/367816","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:367816","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/367816","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"},{"id":"pmid:3785204","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3785204","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1293536","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/367816","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G903233990","display_name":"BIONET, NATIONAL COMPUTER RESOURCE FOR MOLECULAR BIOLOGY","funder_award_id":"5u41rr001685-06","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W200105130","https://openalex.org/W1513717105","https://openalex.org/W1557166240","https://openalex.org/W1557843393","https://openalex.org/W1968568847","https://openalex.org/W1968697334","https://openalex.org/W1977532037","https://openalex.org/W1986383947","https://openalex.org/W2009138461","https://openalex.org/W2010885715","https://openalex.org/W2016613744","https://openalex.org/W2020691332","https://openalex.org/W2026804121","https://openalex.org/W2034277598","https://openalex.org/W2039456340","https://openalex.org/W2041383836","https://openalex.org/W2043246536","https://openalex.org/W2054708395","https://openalex.org/W2055478880","https://openalex.org/W2055551279","https://openalex.org/W2058285100","https://openalex.org/W2059893400","https://openalex.org/W2065723356","https://openalex.org/W2068474796","https://openalex.org/W2078119356","https://openalex.org/W2081612977","https://openalex.org/W2082171608","https://openalex.org/W2082221845","https://openalex.org/W2086208300","https://openalex.org/W2089043917","https://openalex.org/W2091001646","https://openalex.org/W2091239909","https://openalex.org/W2100837269","https://openalex.org/W2124581290","https://openalex.org/W2132417094","https://openalex.org/W2138270253","https://openalex.org/W2147355227","https://openalex.org/W2168150299","https://openalex.org/W2179748281","https://openalex.org/W2328712699","https://openalex.org/W2903038299","https://openalex.org/W2915128049","https://openalex.org/W2917063093","https://openalex.org/W2951959006"],"related_works":["https://openalex.org/W2133245560","https://openalex.org/W2055465887","https://openalex.org/W2082919818","https://openalex.org/W2055551279","https://openalex.org/W4247831415","https://openalex.org/W1828229592","https://openalex.org/W1951630266","https://openalex.org/W2059893400","https://openalex.org/W2054245225","https://openalex.org/W2469219381"],"abstract_inverted_index":{"We":[0,170,189],"analyzed":[1],"the":[2,12,31,81,134,144,154,158,161,176,196,203],"histone":[3,33,85,129],"mRNA":[4],"population":[5],"found":[6,37,94,147,206],"in":[7,18,39,96,107,139,148,184,207],"several":[8],"adult":[9,73,150,187],"tissues":[10,74,108,151],"of":[11,20,25,58,80,127,143,160,175],"sea":[13],"urchin":[14],"Strongylocentrotus":[15],"purpuratus":[16,43,89],"and":[17,27,167,186,191],"testis":[19,40,166],"Lytechinus":[21],"pictus.":[22],"Unique":[23],"species":[24],"H1":[26,48,69,84],"H2b":[28,92,104,113,198],"mRNAs":[29,60],"encoding":[30,132,195],"sperm-specific":[32,121,197],"subtypes":[34],"can":[35],"be":[36],"exclusively":[38,95],"RNA.":[41],"S.":[42,88],"contains":[44,53,90,101],"two":[45,102],"distinct":[46],"testis-specific":[47],"transcripts,":[49],"while":[50,98],"L.":[51,99],"pictus":[52,100],"one":[54,91],"such":[55,103],"transcript.":[56],"Each":[57],"these":[59],"is":[61,119,137,152],"larger":[62],"than":[63,110],"either":[64],"early":[65],"or":[66],"late":[67,82,112,128,177],"embryonic":[68,83],"mRNAs.":[70,105],"Other":[71],"somatic":[72],"contain":[75],"transcripts":[76,114,163],"derived":[77],"from":[78],"members":[79,174],"gene":[86,179],"family.":[87],"transcript":[93],"testis,":[97,111],"Similarly,":[106],"other":[109,168],"were":[115],"found.":[116],"While":[117],"there":[118],"no":[120],"H2a":[122,130,145,162,178],"protein,":[123],"a":[124],"limited":[125],"set":[126],"genes":[131],"primarily":[133],"H2a-beta":[135,155,204],"subtype":[136],"expressed":[138,183],"testis.":[140,208],"The":[141],"majority":[142],"protein":[146,199,205],"diploid":[149],"also":[153],"subtype;":[156],"however,":[157],"size":[159],"differs":[164],"between":[165],"tissues.":[169,188],"conclude":[171],"that":[172],"different":[173],"family":[180],"are":[181],"differentially":[182],"embryos":[185],"prepared":[190],"characterized":[192],"cDNA":[193],"clones":[194],"as":[200,202],"well":[201]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}