{"id":"https://openalex.org/W2121045751","doi":"https://doi.org/10.1111/eci.12393","title":"Circulating cardiac biomarkers and postoperative atrial fibrillation in the OPERA trial","display_name":"Circulating cardiac biomarkers and postoperative atrial fibrillation in the OPERA trial","publication_year":2014,"publication_date":"2014-12-15","ids":{"openalex":"https://openalex.org/W2121045751","doi":"https://doi.org/10.1111/eci.12393","mag":"2121045751","pmid":"https://pubmed.ncbi.nlm.nih.gov/25510286"},"language":"en","primary_location":{"id":"doi:10.1111/eci.12393","doi":"https://doi.org/10.1111/eci.12393","is_oa":false,"landing_page_url":"https://doi.org/10.1111/eci.12393","pdf_url":null,"source":{"id":"https://openalex.org/S153084679","display_name":"European Journal of Clinical Investigation","issn_l":"0014-2972","issn":["0014-2972","1365-2362"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088399069","display_name":"Serge Masson","orcid":"https://orcid.org/0000-0002-1446-0281","observed_orcids":["https://orcid.org/0000-0002-1446-0281"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Serge Masson","raw_affiliation_strings":["Department of Cardiovascular Research IRCCS\u2010Istituto di Ricerche Farmacologiche \u201cMario Negri\u201d Milan Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Research IRCCS\u2010Istituto di Ricerche Farmacologiche \u201cMario Negri\u201d Milan Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101449235","display_name":"Jason H. Y. Wu","orcid":"https://orcid.org/0000-0003-2073-3562","observed_orcids":["https://orcid.org/0000-0003-2073-3562"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I4210110309","display_name":"The George Institute for Global Health","ror":"https://ror.org/023331s46","country_code":"AU","type":"facility","lineage":["https://openalex.org/I4210110309"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jason H. Y. Wu","raw_affiliation_strings":["The George Institute for Global Health, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The George Institute for Global Health, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210110309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103914960","display_name":"Caterina Simon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Caterina Simon","raw_affiliation_strings":["Cardiovascular Department Cardiac Surgery Ospedali Riuniti di Bergamo Bergamo Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Department Cardiac Surgery Ospedali Riuniti di Bergamo Bergamo Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061915173","display_name":"Simona Barlera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Simona Barlera","raw_affiliation_strings":["Department of Cardiovascular Research IRCCS\u2010Istituto di Ricerche Farmacologiche \u201cMario Negri\u201d Milan Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Research IRCCS\u2010Istituto di Ricerche Farmacologiche \u201cMario Negri\u201d Milan Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090813987","display_name":"Roberto Marchioli","orcid":"https://orcid.org/0000-0001-7195-5988","observed_orcids":["https://orcid.org/0000-0001-7195-5988"]},"institutions":[{"id":"https://openalex.org/I28927889","display_name":"IQVIA (United Kingdom)","ror":"https://ror.org/040g76k92","country_code":"GB","type":"company","lineage":["https://openalex.org/I28927889","https://openalex.org/I4210108991"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Roberto Marchioli","raw_affiliation_strings":["Hematology\u2010Oncology Therapeutic Delivery Unit Quintiles Milan Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology\u2010Oncology Therapeutic Delivery Unit Quintiles Milan Italy","institution_ids":["https://openalex.org/I28927889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088786250","display_name":"Javier A. Mariani","orcid":"https://orcid.org/0000-0002-9372-6817","observed_orcids":["https://orcid.org/0000-0002-9372-6817"]},"institutions":[{"id":"https://openalex.org/I4405254531","display_name":"Fundaci\u00f3n GESICA","ror":"https://ror.org/01xm1pt56","country_code":"AR","type":"nonprofit","lineage":["https://openalex.org/I4405254531"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Javier Mariani","raw_affiliation_strings":["GESICA Foundation Buenos Aires Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GESICA Foundation Buenos Aires Argentina","institution_ids":["https://openalex.org/I4405254531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023868945","display_name":"Alejandro Macchia","orcid":"https://orcid.org/0000-0002-5424-5009","observed_orcids":["https://orcid.org/0000-0002-5424-5009"]},"institutions":[{"id":"https://openalex.org/I4405254531","display_name":"Fundaci\u00f3n GESICA","ror":"https://ror.org/01xm1pt56","country_code":"AR","type":"nonprofit","lineage":["https://openalex.org/I4405254531"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Alejandro Macchia","raw_affiliation_strings":["GESICA Foundation Buenos Aires Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GESICA Foundation Buenos Aires Argentina","institution_ids":["https://openalex.org/I4405254531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001390405","display_name":"Federico Lombardi","orcid":"https://orcid.org/0000-0003-2424-2509","observed_orcids":["https://orcid.org/0000-0003-2424-2509"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federico Lombardi","raw_affiliation_strings":["U.O.C. Malattie Cardiovascolari, Fondazione IRCCS Ospedale Maggiore Policlinico, Department of Clinical and Community Sciences, University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.O.C. Malattie Cardiovascolari, Fondazione IRCCS Ospedale Maggiore Policlinico, Department of Clinical and Community Sciences, University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086733235","display_name":"Tarcisio Vago","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087773","display_name":"Luigi Sacco Hospital","ror":"https://ror.org/0025g8755","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210087773","https://openalex.org/I4210156709"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Tarcisio Vago","raw_affiliation_strings":["Laboratory of Endocrinology Ospedale Luigi Sacco Milan Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Endocrinology Ospedale Luigi Sacco Milan Italy","institution_ids":["https://openalex.org/I4210087773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031097183","display_name":"Aneta Aleksova","orcid":"https://orcid.org/0000-0001-7711-9905","observed_orcids":["https://orcid.org/0000-0001-7711-9905"]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]},{"id":"https://openalex.org/I4210164020","display_name":"Azienda Sanitaria Universitaria Integrata di Trieste","ror":"https://ror.org/05g7qp006","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210164020","https://openalex.org/I4405278440"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Aneta Aleksova","raw_affiliation_strings":["Cardiovascular Department \u2018Ospedali Riuniti\u2019 and University of Trieste Trieste Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Department \u2018Ospedali Riuniti\u2019 and University of Trieste Trieste Italy","institution_ids":["https://openalex.org/I142444530","https://openalex.org/I4210164020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035046365","display_name":"Lorella Dreas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]},{"id":"https://openalex.org/I4210164020","display_name":"Azienda Sanitaria Universitaria Integrata di Trieste","ror":"https://ror.org/05g7qp006","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210164020","https://openalex.org/I4405278440"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lorella Dreas","raw_affiliation_strings":["Cardiovascular Department \u2018Ospedali Riuniti\u2019 and University of Trieste Trieste Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Department \u2018Ospedali Riuniti\u2019 and University of Trieste Trieste Italy","institution_ids":["https://openalex.org/I142444530","https://openalex.org/I4210164020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079937687","display_name":"Roberto Rene Favaloro","orcid":"https://orcid.org/0000-0001-8267-759X","observed_orcids":["https://orcid.org/0000-0001-8267-759X"]},"institutions":[{"id":"https://openalex.org/I4210154782","display_name":"Favaloro Foundation","ror":"https://ror.org/053f3rt53","country_code":"AR","type":"facility","lineage":["https://openalex.org/I4210154782"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Roberto R. Favaloro","raw_affiliation_strings":["AR Fundacion Favaloro, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AR Fundacion Favaloro, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I4210154782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031722698","display_name":"Alejandro Hershson","orcid":"https://orcid.org/0000-0001-5296-8732","observed_orcids":["https://orcid.org/0000-0001-5296-8732"]},"institutions":[{"id":"https://openalex.org/I4210154782","display_name":"Favaloro Foundation","ror":"https://ror.org/053f3rt53","country_code":"AR","type":"facility","lineage":["https://openalex.org/I4210154782"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Alejandro R. Hershson","raw_affiliation_strings":["AR Fundacion Favaloro, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AR Fundacion Favaloro, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I4210154782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009748989","display_name":"John D. Puskas","orcid":"https://orcid.org/0000-0003-0459-4750","observed_orcids":["https://orcid.org/0000-0003-0459-4750"]},"institutions":[{"id":"https://openalex.org/I132943300","display_name":"Emory Healthcare","ror":"https://ror.org/00yksxf10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John D. Puskas","raw_affiliation_strings":["Emory Health Care; Atlanta GA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Health Care; Atlanta GA USA","institution_ids":["https://openalex.org/I132943300"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072605763","display_name":"Luca Dozza","orcid":"https://orcid.org/0000-0002-6116-0580","observed_orcids":["https://orcid.org/0000-0002-6116-0580"]},"institutions":[{"id":"https://openalex.org/I4210100680","display_name":"Maria Cecilia Hospital","ror":"https://ror.org/01wxb8362","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210100680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Dozza","raw_affiliation_strings":["E.S. Research Foundation GVM Care and Research Maria Cecilia Hospital Cotignola Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E.S. Research Foundation GVM Care and Research Maria Cecilia Hospital Cotignola Italy","institution_ids":["https://openalex.org/I4210100680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108412760","display_name":"Maria Giuseppina Silletta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110338","display_name":"Mario Negri Sud Foundation","ror":"https://ror.org/01qd3xc93","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210110338"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria G. Silletta","raw_affiliation_strings":["Laboratory of Clinical Epidemiology of Cardiovascular Disease Fondazione Mario Negri Sud Santa Maria Imbaro Italy","Fondazione Mario Negri Sud Laboratory of Clinical Epidemiology of Cardiovascular Disease Santa Maria Imbaro Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Epidemiology of Cardiovascular Disease Fondazione Mario Negri Sud Santa Maria Imbaro Italy","institution_ids":["https://openalex.org/I4210110338"]},{"raw_affiliation_string":"Fondazione Mario Negri Sud Laboratory of Clinical Epidemiology of Cardiovascular Disease Santa Maria Imbaro Italy","institution_ids":["https://openalex.org/I4210110338"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111939204","display_name":"Gianni Tognoni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110338","display_name":"Mario Negri Sud Foundation","ror":"https://ror.org/01qd3xc93","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210110338"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianni Tognoni","raw_affiliation_strings":["Laboratory of Clinical Epidemiology of Cardiovascular Disease Fondazione Mario Negri Sud Santa Maria Imbaro Italy","Fondazione Mario Negri Sud Laboratory of Clinical Epidemiology of Cardiovascular Disease Santa Maria Imbaro Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Epidemiology of Cardiovascular Disease Fondazione Mario Negri Sud Santa Maria Imbaro Italy","institution_ids":["https://openalex.org/I4210110338"]},{"raw_affiliation_string":"Fondazione Mario Negri Sud Laboratory of Clinical Epidemiology of Cardiovascular Disease Santa Maria Imbaro Italy","institution_ids":["https://openalex.org/I4210110338"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064987258","display_name":"Dariush Mozaffarian","orcid":"https://orcid.org/0000-0001-7958-9492","observed_orcids":["https://orcid.org/0000-0001-7958-9492"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dariush Mozaffarian","raw_affiliation_strings":["Departments of Epidemiology and Nutrition, Harvard School of Public Health, Boston, MA, USA","Division of Cardiovascular Medicine and Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Epidemiology and Nutrition, Harvard School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Cardiovascular Medicine and Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027518592","display_name":"Roberto Latini","orcid":"https://orcid.org/0000-0002-3729-4650","observed_orcids":["https://orcid.org/0000-0002-3729-4650"]},"institutions":[{"id":"https://openalex.org/I19630809","display_name":"Mario Negri Institute for Pharmacological Research","ror":"https://ror.org/05aspc753","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I19630809","https://openalex.org/I4210110338","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Roberto Latini","raw_affiliation_strings":["Department of Cardiovascular Research IRCCS\u2010Istituto di Ricerche Farmacologiche \u201cMario Negri\u201d Milan Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Research IRCCS\u2010Istituto di Ricerche Farmacologiche \u201cMario Negri\u201d Milan Italy","institution_ids":["https://openalex.org/I19630809"]}]},{"author_position":"last","author":{"id":null,"display_name":"the OPERA Investigators","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"the OPERA Investigators","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5027518592"],"corresponding_institution_ids":["https://openalex.org/I19630809"],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":null,"fwci":2.4268,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.90052066,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"45","issue":"2","first_page":"170","last_page":"178"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11930","display_name":"Cardiac, Anesthesia and Surgical Outcomes","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postoperative-atrial-fibrillation","display_name":"postoperative atrial fibrillation","score":1.0},{"id":"https://openalex.org/keywords/cardiac-surgery","display_name":"cardiac surgery","score":0.7319999933242798},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.8930000066757202},{"id":"https://openalex.org/keywords/high-sensitivity-troponin-t","display_name":"high-sensitivity troponin T","score":0.9760000109672546},{"id":"https://openalex.org/keywords/circulating-biomarkers","display_name":"circulating biomarkers","score":0.781000018119812},{"id":"https://openalex.org/keywords/fish-oil-supplementation","display_name":"fish oil supplementation","score":0.9340000152587891},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.953000009059906},{"id":"https://openalex.org/keywords/risk-prediction","display_name":"risk prediction","score":0.6119999885559082},{"id":"https://openalex.org/keywords/opera-trial","display_name":"OPERA trial","score":0.9070000052452087}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9105389714241028},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.6857065558433533},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.6799612045288086},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.6143571734428406},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6028838157653809},{"id":"https://openalex.org/C144469398","wikidata":"https://www.wikidata.org/wiki/Q24785650","display_name":"Troponin T","level":3,"score":0.5395869612693787},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5394836664199829},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.4401931166648865},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.43511003255844116},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.3988424241542816},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.3413037359714508},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3286331593990326},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.15363654494285583}],"mesh":[{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006348","descriptor_name":"Cardiac Surgical Procedures","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011182","descriptor_name":"Postoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011300","descriptor_name":"Preoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020097","descriptor_name":"Natriuretic Peptide, Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020107","descriptor_name":"Troponin T","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1111/eci.12393","doi":"https://doi.org/10.1111/eci.12393","is_oa":false,"landing_page_url":"https://doi.org/10.1111/eci.12393","pdf_url":null,"source":{"id":"https://openalex.org/S153084679","display_name":"European Journal of Clinical Investigation","issn_l":"0014-2972","issn":["0014-2972","1365-2362"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Investigation","raw_type":"journal-article"},{"id":"pmid:25510286","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25510286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical investigation","raw_type":"Journal Article"},{"id":"pmh:oai:arts.units.it:11368/2835875","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11368/2835875","pdf_url":null,"source":{"id":"https://openalex.org/S4306400480","display_name":"ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142444530","host_organization_name":"University of Trieste","host_organization_lineage":["https://openalex.org/I142444530"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unito.it:2318/1573004","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2318/1573004","pdf_url":null,"source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1672479910","display_name":"Ancillary: Inflammation/Oxidation, Omega-3's, & Post-Op AFiB & Cognitive Decline","funder_award_id":"5rc2hl101816-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2665021247","display_name":"Endogenous Anti-Inflammatory Lipid Mediators, Fish Oil and Post-Operative Atrial","funder_award_id":"R21HL109924","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5750759045","display_name":null,"funder_award_id":"RC2-HL101816","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6311200642","display_name":null,"funder_award_id":"1 RC2 HL101816","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8520344925","display_name":"RAAS, Inflammation & Post-Operative Atrial Fibrillation","funder_award_id":"R01HL077389","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000910297","display_name":"Surgical Treatment of Cardiac Arrhythmias","funder_award_id":"R01HL032257","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1971991644","https://openalex.org/W2004717131","https://openalex.org/W2006691385","https://openalex.org/W2007591654","https://openalex.org/W2034210960","https://openalex.org/W2038093356","https://openalex.org/W2044563880","https://openalex.org/W2053771438","https://openalex.org/W2065563234","https://openalex.org/W2078272177","https://openalex.org/W2078856783","https://openalex.org/W2093415459","https://openalex.org/W2110286409","https://openalex.org/W2120795994","https://openalex.org/W2126487848","https://openalex.org/W2127911359","https://openalex.org/W2132461325","https://openalex.org/W2134699132","https://openalex.org/W2135560741","https://openalex.org/W2150954212","https://openalex.org/W2152255107","https://openalex.org/W2157109101","https://openalex.org/W2165142491","https://openalex.org/W2169526624","https://openalex.org/W2169902118","https://openalex.org/W2546425606","https://openalex.org/W3175417087"],"related_works":["https://openalex.org/W1509040603","https://openalex.org/W3041106452","https://openalex.org/W4413050377","https://openalex.org/W4390146864","https://openalex.org/W2187766903","https://openalex.org/W3112600756","https://openalex.org/W2150954212","https://openalex.org/W2741986532","https://openalex.org/W2132461325","https://openalex.org/W4205253466"],"abstract_inverted_index":{"BACKGROUND:":[0],"Postoperative":[1],"atrial":[2],"fibrillation":[3],"(POAF)":[4],"is":[5],"a":[6],"common":[7],"complication":[8],"after":[9,207],"cardiac":[10,57,69,82,138,175,218],"surgery":[11,130,160,198],"and":[12,16,55,74,119,127,140,199,211,221,227],"predicts":[13],"increased":[14],"morbidity":[15],"mortality.":[17],"Identification":[18],"of":[19,24,29,49,68,101,125,159,173,181,188,197,242],"patients":[20,80,216],"at":[21,63,71,156],"high":[22],"risk":[23,241],"POAF":[25,112,206],"with":[26,88,133,205,240],"the":[27,66,95,157,170,174,186],"help":[28],"circulating":[30],"biomarkers":[31,176],"may":[32],"enable":[33],"early":[34],"preventive":[35],"treatment":[36],"but":[37,235],"data":[38],"are":[39,223,236],"limited,":[40],"especially":[41],"in":[42,78,94,192],"contemporary":[43],"surgical":[44,212,228],"patients.":[45],"METHODS:":[46],"Plasma":[47],"concentrations":[48],"N-terminal":[50],"pro-B-type":[51],"natriuretic":[52],"peptide":[53],"(NT-proBNP)":[54],"high-sensitivity":[56],"troponin":[58],"T":[59],"(hs-cTnT)":[60],"were":[61,131,201],"measured":[62],"enrollment,":[64],"on":[65,144,185],"morning":[67,187,196],"surgery,":[70,73,83,189,219],"end":[72,158],"2":[75,147],"days":[76],"postsurgery":[77],"562":[79],"undergoing":[81,217],"randomized":[84],"to":[85,225],"perioperative":[86,232],"supplementation":[87,166],"oral":[89],"fish":[90],"oil":[91,165],"or":[92,137,183,190],"placebo":[93],"Omega-3":[96],"Fatty":[97],"Acids":[98],"for":[99,209],"Prevention":[100],"Post-Operative":[102],"Atrial":[103],"Fibrillation":[104],"trial":[105],"(OPERA).":[106],"The":[107],"primary":[108],"endpoint":[109],"was":[110],"incident":[111],"lasting":[113],"\u2265":[114],"30":[115],"s,":[116],"centrally":[117],"adjudicated":[118],"confirmed":[120],"electrocardiographically.":[121],"RESULTS:":[122],"Higher":[123],"levels":[124],"NT-proBNP":[126,142,182,220],"hs-cTnT":[128,154,222],"before":[129],"associated":[132,204,239],"older":[134],"age,":[135],"renal":[136],"dysfunction":[139],"EuroSCORE.":[141],"peaked":[143,155],"postoperative":[145],"day":[146],"(2172":[148],"[1238-3758]":[149],"ng/L,":[150],"median":[151],"[Q1-Q3]),":[152],"while":[153],"(373":[161],"[188-660]":[162],"ng/L).":[163],"Fish":[164],"did":[167],"not":[168,202,237],"alter":[169],"time":[171,233],"course":[172],"(P":[177],">":[178],"0.05).":[179],"Concentrations":[180],"hs-cTnT,":[184],"changes":[191],"their":[193],"level":[194],"between":[195],"postsurgery,":[200],"significantly":[203],"adjustment":[208],"clinical":[210,226],"characteristics.":[213],"CONCLUSION:":[214],"Among":[215],"related":[224],"characteristics,":[229],"have":[230],"different":[231],"courses":[234],"independently":[238],"POAF.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}