{"id":"https://openalex.org/W2121005897","doi":"https://doi.org/10.1523/jneurosci.1732-07.2007","title":"Cholinergic Axons Modulate GABAergic Signaling among Hippocampal Interneurons via Postsynaptic \u03b17 Nicotinic Receptors","display_name":"Cholinergic Axons Modulate GABAergic Signaling among Hippocampal Interneurons via Postsynaptic \u03b17 Nicotinic Receptors","publication_year":2007,"publication_date":"2007-05-23","ids":{"openalex":"https://openalex.org/W2121005897","doi":"https://doi.org/10.1523/jneurosci.1732-07.2007","mag":"2121005897","pmid":"https://pubmed.ncbi.nlm.nih.gov/17522313","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2889598"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.1732-07.2007","doi":"https://doi.org/10.1523/jneurosci.1732-07.2007","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.1732-07.2007","pdf_url":"https://www.jneurosci.org/content/jneuro/27/21/5683.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/27/21/5683.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017953548","display_name":"Nicolas Wanaverbecq","orcid":"https://orcid.org/0000-0001-5486-2771","observed_orcids":["https://orcid.org/0000-0001-5486-2771"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicolas Wanaverbecq","raw_affiliation_strings":["Institute of Neurology, University College London, London WC1N 3BG, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neurology, University College London, London WC1N 3BG, United Kingdom","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040470106","display_name":"Alexey V. Semyanov","orcid":"https://orcid.org/0000-0002-6800-0942","observed_orcids":["https://orcid.org/0000-0002-6800-0942"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexey Semyanov","raw_affiliation_strings":["Institute of Neurology, University College London, London WC1N 3BG, United Kingdom","Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neurology, University College London, London WC1N 3BG, United Kingdom","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075289165","display_name":"Ivan Pavlov","orcid":"https://orcid.org/0000-0003-1266-6988","observed_orcids":["https://orcid.org/0000-0003-1266-6988"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ivan Pavlov","raw_affiliation_strings":["Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081465083","display_name":"Matthew C. Walker","orcid":"https://orcid.org/0000-0002-0812-0352","observed_orcids":["https://orcid.org/0000-0002-0812-0352"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew C. Walker","raw_affiliation_strings":["Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033570060","display_name":"Dimitri Michael Kullmann","orcid":"https://orcid.org/0000-0001-6696-3545","observed_orcids":["https://orcid.org/0000-0001-6696-3545"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Dimitri M. Kullmann","raw_affiliation_strings":["Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neurology, University College London, London WC1N 3BG, United Kingdom, and","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5033570060"],"corresponding_institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"],"apc_list":null,"apc_paid":null,"fwci":3.1553,"has_fulltext":true,"cited_by_count":74,"citation_normalized_percentile":{"value":0.93233154,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"27","issue":"21","first_page":"5683","last_page":"5693"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.057999998331069946,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha7-nicotinic-acetylcholine-receptor","display_name":"alpha7 nicotinic acetylcholine receptor","score":0.9240000247955322},{"id":"https://openalex.org/keywords/cholinergic-modulation","display_name":"cholinergic modulation","score":0.7009999752044678},{"id":"https://openalex.org/keywords/hippocampal-interneurons","display_name":"hippocampal interneurons","score":0.9300000071525574},{"id":"https://openalex.org/keywords/gabaergic-inhibition","display_name":"GABAergic inhibition","score":0.7409999966621399},{"id":"https://openalex.org/keywords/heterosynaptic-depression","display_name":"heterosynaptic depression","score":0.8479999899864197},{"id":"https://openalex.org/keywords/gaba-release","display_name":"GABA release","score":0.7570000290870667},{"id":"https://openalex.org/keywords/postsynaptic-modulation","display_name":"postsynaptic modulation","score":0.7160000205039978},{"id":"https://openalex.org/keywords/stratum-radiatum","display_name":"stratum radiatum","score":0.7350000143051147},{"id":"https://openalex.org/keywords/ca1","display_name":"CA1","score":0.8259999752044678},{"id":"https://openalex.org/keywords/cholinergic-axons","display_name":"cholinergic axons","score":0.6869999766349792},{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.47600001096725464},{"id":"https://openalex.org/keywords/protein-kinase-c","display_name":"protein kinase C","score":0.9350000023841858},{"id":"https://openalex.org/keywords/cholinesterase-inhibition","display_name":"cholinesterase inhibition","score":0.7179999947547913},{"id":"https://openalex.org/keywords/synaptic-integration","display_name":"synaptic integration","score":0.5569999814033508}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7904585599899292},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.7352491617202759},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.6839138269424438},{"id":"https://openalex.org/C2779177108","wikidata":"https://www.wikidata.org/wiki/Q18356742","display_name":"GABAergic","level":3,"score":0.6784033179283142},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.5654885768890381},{"id":"https://openalex.org/C188987157","wikidata":"https://www.wikidata.org/wiki/Q7030581","display_name":"Nicotinic agonist","level":3,"score":0.5434187054634094},{"id":"https://openalex.org/C2779296341","wikidata":"https://www.wikidata.org/wiki/Q1500732","display_name":"Interneuron","level":3,"score":0.4315243065357208},{"id":"https://openalex.org/C80161118","wikidata":"https://www.wikidata.org/wiki/Q408520","display_name":"Acetylcholine receptor","level":3,"score":0.41891491413116455},{"id":"https://openalex.org/C187541742","wikidata":"https://www.wikidata.org/wiki/Q4374336","display_name":"Postsynaptic density","level":4,"score":0.4187946319580078},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3731563687324524},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.36744871735572815},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3575710356235504},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.25195837020874023},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.2291032373905182},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.047815144062042236}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002799","descriptor_name":"Cholinergic Fibers","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002799","descriptor_name":"Cholinergic Fibers","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005680","descriptor_name":"gamma-Aminobutyric Acid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011963","descriptor_name":"Receptors, GABA-A","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011978","descriptor_name":"Receptors, Nicotinic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018722","descriptor_name":"Nicotinic Agonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064569","descriptor_name":"alpha7 Nicotinic Acetylcholine Receptor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1523/jneurosci.1732-07.2007","doi":"https://doi.org/10.1523/jneurosci.1732-07.2007","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.1732-07.2007","pdf_url":"https://www.jneurosci.org/content/jneuro/27/21/5683.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1955615","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2889598","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2889598","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2889598","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"pmid:17522313","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17522313","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Comparative Study"},{"id":"pmh:oai:HAL:hal-03614095v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-03614095","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Neuroscience, 2007, 27 (21), pp.5683-5693. ⟨10.1523/JNEUROSCI.1732-07.2007⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:134552","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/134552/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J NEUROSCI , 27 (21) 5683 - 5693. (2007)","raw_type":"Article"},{"id":"mag:2184790186","doi":null,"is_oa":false,"landing_page_url":"https://www.jneurosci.org/content/27/21/5683.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1523/jneurosci.1732-07.2007","doi":"https://doi.org/10.1523/jneurosci.1732-07.2007","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.1732-07.2007","pdf_url":"https://www.jneurosci.org/content/jneuro/27/21/5683.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.428600013256073}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2121005897.pdf","grobid_xml":"https://content.openalex.org/works/W2121005897.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W1492921042","https://openalex.org/W1493574533","https://openalex.org/W1516353901","https://openalex.org/W1519261920","https://openalex.org/W1553854216","https://openalex.org/W1563745248","https://openalex.org/W1575167357","https://openalex.org/W1605530892","https://openalex.org/W1630155501","https://openalex.org/W1658505334","https://openalex.org/W1782407940","https://openalex.org/W1833238563","https://openalex.org/W1845046061","https://openalex.org/W1867921149","https://openalex.org/W1900806927","https://openalex.org/W1934489743","https://openalex.org/W1964737820","https://openalex.org/W1965549069","https://openalex.org/W1968593789","https://openalex.org/W1968669125","https://openalex.org/W1970616082","https://openalex.org/W1970753953","https://openalex.org/W1971009901","https://openalex.org/W1974146730","https://openalex.org/W1979465510","https://openalex.org/W1984746596","https://openalex.org/W1986540496","https://openalex.org/W2000757833","https://openalex.org/W2005491437","https://openalex.org/W2017144423","https://openalex.org/W2018885303","https://openalex.org/W2026331058","https://openalex.org/W2035504473","https://openalex.org/W2043233340","https://openalex.org/W2048375139","https://openalex.org/W2050455764","https://openalex.org/W2056722870","https://openalex.org/W2057196462","https://openalex.org/W2059234084","https://openalex.org/W2062419094","https://openalex.org/W2075044108","https://openalex.org/W2075300430","https://openalex.org/W2085961089","https://openalex.org/W2086269846","https://openalex.org/W2086961654","https://openalex.org/W2089911871","https://openalex.org/W2090019512","https://openalex.org/W2092244912","https://openalex.org/W2092727345","https://openalex.org/W2095265457","https://openalex.org/W2101234460","https://openalex.org/W2102268999","https://openalex.org/W2102405317","https://openalex.org/W2103135119","https://openalex.org/W2104227586","https://openalex.org/W2106189090","https://openalex.org/W2112157534","https://openalex.org/W2113971423","https://openalex.org/W2115460562","https://openalex.org/W2116359609","https://openalex.org/W2117649172","https://openalex.org/W2124793944","https://openalex.org/W2133219198","https://openalex.org/W2141650485","https://openalex.org/W2143458587","https://openalex.org/W2144671685","https://openalex.org/W2159887246","https://openalex.org/W2161214225","https://openalex.org/W2164632177","https://openalex.org/W2168988224","https://openalex.org/W2170136226","https://openalex.org/W2171712409","https://openalex.org/W2342037587","https://openalex.org/W2883323228","https://openalex.org/W3166732914","https://openalex.org/W4234060991","https://openalex.org/W4285719527","https://openalex.org/W4406421852"],"related_works":["https://openalex.org/W2184790186","https://openalex.org/W2020413582","https://openalex.org/W2026331058","https://openalex.org/W2216018617","https://openalex.org/W7100278881","https://openalex.org/W2068608417","https://openalex.org/W1833238563","https://openalex.org/W2168574663","https://openalex.org/W1605530892","https://openalex.org/W2137751464"],"abstract_inverted_index":{"Homopentameric":[0],"alpha7":[1,59,74,94,182],"nicotinic":[2,23,75,124],"receptors":[3,60,76,95],"have":[4,55],"a":[5,117,141,202],"high":[6],"affinity":[7],"for":[8],"acetylcholine":[9],"(ACh),":[10],"are":[11,17],"permeable":[12],"to":[13,64,173],"Ca2+":[14,29,156],"ions,":[15],"and":[16,28,161],"abundant":[18],"in":[19,31,40,87,101,105,120,133,157,189,212],"hippocampal":[20],"interneurons.":[21,88,190],"Although":[22],"agonists":[24,92,126],"evoke":[25,180],"inward":[26],"currents":[27,132,151],"transients":[30],"stratum":[32,102],"radiatum":[33,103],"interneurons,":[34,134],"the":[35,71,106,110,137,158,213],"role":[36],"of":[37,93,109,144,149,165,186],"endogenous":[38,175],"ACh":[39,79,176],"modulating":[41],"synaptic":[42,65],"integration":[43],"by":[44,78,116,154,163,196,205],"interneurons":[45,104],"is":[46,114,140,152,194],"incompletely":[47],"understood.":[48],"Many":[49],"cholinergic":[50,82,178,207],"axonal":[51],"varicosities":[52],"do":[53],"not":[54],"postsynaptic":[56,142],"specializations,":[57],"but":[58],"frequently":[61],"occur":[62],"close":[63],"GABA(A)":[66,145],"receptors.":[67,146],"These":[68,199],"observations":[69],"raise":[70],"possibility":[72],"that":[73,91,136,170],"activated":[77],"released":[80],"from":[81,177],"axons":[83,179],"modulate":[84,209],"GABAergic":[85,98,187],"transmission":[86],"We":[89,167],"show":[90,169],"profoundly":[96],"depress":[97,128],"IPSCs":[99,188],"recorded":[100,159],"CA1":[107],"region":[108],"hippocampus.":[111,214],"This":[112,191],"depression":[113,148,185],"accompanied":[115],"small":[118],"increase":[119],"GABA":[121],"release.":[122],"Alpha7":[123],"receptor":[125],"also":[127,168],"GABA-":[129],"or":[130],"muscimol-evoked":[131],"indicating":[135],"major":[138],"effect":[139],"modulation":[143,193],"The":[147],"GABA-evoked":[150],"abolished":[153],"chelating":[155],"interneuron":[160],"attenuated":[162],"inhibitors":[164],"PKC.":[166],"stimuli":[171],"designed":[172],"release":[174],"an":[181],"receptor-dependent":[183],"heterosynaptic":[184,192],"amplified":[195],"blocking":[197],"cholinesterases.":[198],"results":[200],"reveal":[201],"novel":[203],"mechanism":[204],"which":[206],"neurons":[208],"information":[210],"processing":[211]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}