{"id":"https://openalex.org/W2121003260","doi":"https://doi.org/10.1073/pnas.0903280106","title":"Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions","display_name":"Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions","publication_year":2009,"publication_date":"2009-07-27","ids":{"openalex":"https://openalex.org/W2121003260","doi":"https://doi.org/10.1073/pnas.0903280106","mag":"2121003260","pmid":"https://pubmed.ncbi.nlm.nih.gov/19651606","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2726360"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.0903280106","doi":"https://doi.org/10.1073/pnas.0903280106","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0903280106","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2726360","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005151225","display_name":"Sergei A. Grigoryev","orcid":"https://orcid.org/0000-0003-1890-1862","observed_orcids":["https://orcid.org/0000-0003-1890-1862"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sergei A. Grigoryev","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, H171, Milton S. Hershey Medical Center, P.O. Box 850, 500 University Drive, Hershey, PA 17033;","Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, H171, Milton S. Hershey Medical Center, PO Box 850, 500 University Drive, Hershey, PA 17033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, H171, Milton S. Hershey Medical Center, P.O. Box 850, 500 University Drive, Hershey, PA 17033;","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, H171, Milton S. Hershey Medical Center, PO Box 850, 500 University Drive, Hershey, PA 17033, USA","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084515376","display_name":"Gaurav Arya","orcid":"https://orcid.org/0000-0002-5615-0521","observed_orcids":["https://orcid.org/0000-0002-5615-0521"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gaurav Arya","raw_affiliation_strings":["Department of Nanoengineering, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nanoengineering, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093;","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003657173","display_name":"Sarah Correll","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Correll","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, H171, Milton S. Hershey Medical Center, P.O. Box 850, 500 University Drive, Hershey, PA 17033;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, H171, Milton S. Hershey Medical Center, P.O. Box 850, 500 University Drive, Hershey, PA 17033;","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111866704","display_name":"Christopher L. F. Woodcock","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24603500","display_name":"University of Massachusetts Amherst","ror":"https://ror.org/0072zz521","country_code":"US","type":"education","lineage":["https://openalex.org/I24603500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher L. Woodcock","raw_affiliation_strings":["Biology Department, University of Massachusetts, Amherst, MA 01003; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, University of Massachusetts, Amherst, MA 01003; and","institution_ids":["https://openalex.org/I24603500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046513501","display_name":"Tamar Schlick A","orcid":"https://orcid.org/0000-0002-2392-2062","observed_orcids":["https://orcid.org/0000-0002-2392-2062"]},"institutions":[{"id":"https://openalex.org/I36672615","display_name":"Courant Institute of Mathematical Sciences","ror":"https://ror.org/037tm7f56","country_code":"US","type":"education","lineage":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamar Schlick","raw_affiliation_strings":["Department of Chemistry and Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, NY 10012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, NY 10012","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.4996,"has_fulltext":false,"cited_by_count":263,"citation_normalized_percentile":{"value":0.98740697,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"106","issue":"32","first_page":"13317","last_page":"13322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/30-nm-chromatin-fiber","display_name":"30 nm chromatin fiber","score":0.9380000233650208},{"id":"https://openalex.org/keywords/linker-histones","display_name":"linker histones","score":0.7419999837875366},{"id":"https://openalex.org/keywords/divalent-cations","display_name":"divalent cations","score":0.7440000176429749},{"id":"https://openalex.org/keywords/solenoid-model","display_name":"solenoid model","score":0.7170000076293945}],"concepts":[{"id":"https://openalex.org/C193646685","wikidata":"https://www.wikidata.org/wiki/Q1826830","display_name":"Linker DNA","level":5,"score":0.898809552192688},{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.7890281677246094},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.7497419714927673},{"id":"https://openalex.org/C2780557392","wikidata":"https://www.wikidata.org/wiki/Q523796","display_name":"Linker","level":2,"score":0.7176167368888855},{"id":"https://openalex.org/C164974683","wikidata":"https://www.wikidata.org/wiki/Q1044051","display_name":"Chromatosome","level":5,"score":0.6826516389846802},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.6005311012268066},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.577977180480957},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5385196805000305},{"id":"https://openalex.org/C192144188","wikidata":"https://www.wikidata.org/wiki/Q245739","display_name":"Solenoid","level":2,"score":0.5249229073524475},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.375016450881958},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3719823956489563},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3288259506225586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2928905189037323},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.20218446850776672},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1841488778591156},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09054926037788391},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1073/pnas.0903280106","doi":"https://doi.org/10.1073/pnas.0903280106","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0903280106","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2726360","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2726360","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:19651606","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19651606","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2726360","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2726360","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4845988523","display_name":"Modeling Chromatin Organization and Function","funder_award_id":"R01GM055164","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W1963540515","https://openalex.org/W1966033200","https://openalex.org/W1967560809","https://openalex.org/W1968894421","https://openalex.org/W1969691479","https://openalex.org/W1976094626","https://openalex.org/W1983459461","https://openalex.org/W1985460850","https://openalex.org/W1988997227","https://openalex.org/W2004694336","https://openalex.org/W2012525958","https://openalex.org/W2013106892","https://openalex.org/W2013625458","https://openalex.org/W2017314177","https://openalex.org/W2029931866","https://openalex.org/W2030023744","https://openalex.org/W2036663535","https://openalex.org/W2038132544","https://openalex.org/W2040048585","https://openalex.org/W2044107593","https://openalex.org/W2048350558","https://openalex.org/W2049108972","https://openalex.org/W2052757247","https://openalex.org/W2052842503","https://openalex.org/W2054669424","https://openalex.org/W2059294991","https://openalex.org/W2059777793","https://openalex.org/W2061111901","https://openalex.org/W2067267228","https://openalex.org/W2076702777","https://openalex.org/W2078912121","https://openalex.org/W2081127803","https://openalex.org/W2084250387","https://openalex.org/W2091747182","https://openalex.org/W2093351957","https://openalex.org/W2099114692","https://openalex.org/W2099997590","https://openalex.org/W2100581810","https://openalex.org/W2116097904","https://openalex.org/W2117275660","https://openalex.org/W2128254777","https://openalex.org/W2129002407","https://openalex.org/W2135570120","https://openalex.org/W2143444693","https://openalex.org/W2144792857","https://openalex.org/W2147473525","https://openalex.org/W2149917410","https://openalex.org/W2154736293","https://openalex.org/W2157366872","https://openalex.org/W2158378515","https://openalex.org/W2165451373","https://openalex.org/W2166633156","https://openalex.org/W2172170093","https://openalex.org/W2406443600"],"related_works":["https://openalex.org/W7095186514","https://openalex.org/W1967560809","https://openalex.org/W2157366872","https://openalex.org/W2076702777","https://openalex.org/W3178191256","https://openalex.org/W1581574659","https://openalex.org/W3129867584","https://openalex.org/W2172170093","https://openalex.org/W2165451373","https://openalex.org/W2040048585"],"abstract_inverted_index":{"The":[0],"architecture":[1],"of":[2,25,34,50,148],"the":[3,22,26,79,108,133,141,146,190],"chromatin":[4,28,111,164],"fiber,":[5,29],"which":[6],"determines":[7],"DNA":[8,103,130,150,178],"accessibility":[9],"for":[10],"transcription":[11],"and":[12,70,88,100,118,145,183,200],"other":[13],"template-directed":[14],"biological":[15],"processes,":[16],"remains":[17],"unknown.":[18],"Here":[19],"we":[20],"investigate":[21],"internal":[23],"organization":[24],"30-nm":[27,198],"combining":[30],"Monte":[31],"Carlo":[32],"simulations":[33],"nucleosome":[35,40,92,194],"chain":[36],"folding":[37],"with":[38,166],"EM-assisted":[39],"interaction":[41],"capture":[42],"(EMANIC).":[43],"We":[44],"show":[45,139],"that":[46,140,152,175],"at":[47],"physiological":[48],"concentrations":[49],"monovalent":[51],"ions,":[52],"linker":[53,86,102,149,177,181],"histones":[54,182],"lead":[55],"to":[56],"a":[57,161],"tight":[58,193],"2-start":[59,142],"zigzag":[60,143],"dominated":[61],"by":[62,72,81,180],"interactions":[63,93],"between":[64,192],"alternate":[65],"nucleosomes":[66],"(i":[67,94],"+/-":[68,95],"2)":[69],"sealed":[71],"histone":[73],"N-tails.":[74],"Divalent":[75],"ions":[76],"further":[77],"compact":[78,110],"fiber":[80,112,134,165],"promoting":[82],"bending":[83,151,179],"in":[84,107,160,186],"some":[85],"DNAs":[87],"hence":[89],"raising":[90],"sequential":[91],"1).":[96],"Remarkably,":[97],"both":[98,116],"straight":[99],"bent":[101],"conformations":[104],"are":[105],"retained":[106],"fully":[109],"as":[113,126],"inferred":[114],"from":[115],"EMANIC":[117],"modeling.":[119],"This":[120],"conformational":[121],"variability":[122],"is":[123],"energetically":[124],"favorable":[125],"it":[127],"helps":[128],"accommodate":[129],"crossings":[131],"within":[132,196],"axis.":[135],"Our":[136,171],"results":[137],"thus":[138],"topology":[144],"type":[147],"defines":[153],"solenoid":[154],"models":[155],"may":[156,188],"be":[157],"simultaneously":[158],"present":[159],"structurally":[162],"heteromorphic":[163],"uniform":[167],"30":[168],"nm":[169],"diameter.":[170],"data":[172],"also":[173],"suggest":[174],"dynamic":[176],"divalent":[184],"cations":[185],"vivo":[187],"mediate":[189],"transition":[191],"packing":[195],"discrete":[197],"fibers":[199],"self-associated":[201],"higher-order":[202],"chromosomal":[203],"forms.":[204]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":28},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":16},{"year":2012,"cited_by_count":22}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}