{"id":"https://openalex.org/W2120902205","doi":"https://doi.org/10.1007/s10194-009-0109-3","title":"Sneddon\u2019s syndrome presenting with severe disabling bilateral headache","display_name":"Sneddon\u2019s syndrome presenting with severe disabling bilateral headache","publication_year":2009,"publication_date":"2009-03-13","ids":{"openalex":"https://openalex.org/W2120902205","doi":"https://doi.org/10.1007/s10194-009-0109-3","mag":"2120902205","pmid":"https://pubmed.ncbi.nlm.nih.gov/19288055","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3451989"},"language":"en","primary_location":{"id":"doi:10.1007/s10194-009-0109-3","doi":"https://doi.org/10.1007/s10194-009-0109-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10194-009-0109-3","pdf_url":"https://thejournalofheadacheandpain.biomedcentral.com/counter/pdf/10.1007/s10194-009-0109-3","source":{"id":"https://openalex.org/S143427143","display_name":"The Journal of Headache and Pain","issn_l":"1129-2369","issn":["1129-2369","1129-2377"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Headache and Pain","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://thejournalofheadacheandpain.biomedcentral.com/counter/pdf/10.1007/s10194-009-0109-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007748007","display_name":"Cinzia Cavestro","orcid":"https://orcid.org/0000-0003-1172-1009","observed_orcids":["https://orcid.org/0000-0003-1172-1009"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Cinzia Cavestro","raw_affiliation_strings":["Department of Neurology, Headache Center, Ospedale San Lazzaro A.S.L., Alba (CN), Italy. cicaves@tin.it","Department of Neurology, Headache Center, Ospedale \u201cSan Lazzaro\u201d A.S.L. CN2, Alba (CN), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Headache Center, Ospedale San Lazzaro A.S.L., Alba (CN), Italy. cicaves@tin.it","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, Headache Center, Ospedale \u201cSan Lazzaro\u201d A.S.L. CN2, Alba (CN), Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045434832","display_name":"Luca Richetta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luca Richetta","raw_affiliation_strings":["Department of Radiology, Fossano Hospital, Fossano (CN), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Fossano Hospital, Fossano (CN), Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033568098","display_name":"Enrico Pedemonte","orcid":"https://orcid.org/0000-0002-7325-5384","observed_orcids":["https://orcid.org/0000-0002-7325-5384"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Enrico Pedemonte","raw_affiliation_strings":["Department of Neurology, \u201cSan Lazzaro\u201d Hospital, Alba, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, \u201cSan Lazzaro\u201d Hospital, Alba, Italy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012374595","display_name":"G. Asteggiano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanni Asteggiano","raw_affiliation_strings":["Department of Neurology, \u201cSan Lazzaro\u201d Hospital, Alba, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, \u201cSan Lazzaro\u201d Hospital, Alba, Italy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5007748007"],"corresponding_institution_ids":[],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":{"value":3990,"currency":"USD","value_usd":3990},"fwci":0.0,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"10","issue":"3","first_page":"211","last_page":"213"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.9291999936103821,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.9291999936103821,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sneddon-syndrome","display_name":"Sneddon syndrome","score":0.9940000176429749},{"id":"https://openalex.org/keywords/headache","display_name":"headache","score":0.3799999952316284},{"id":"https://openalex.org/keywords/livedo-reticularis","display_name":"livedo reticularis","score":0.9470000267028809},{"id":"https://openalex.org/keywords/lacunar-infarction","display_name":"lacunar infarction","score":0.8539999723434448},{"id":"https://openalex.org/keywords/ticlopidine","display_name":"ticlopidine","score":0.6759999990463257},{"id":"https://openalex.org/keywords/pentoxifylline","display_name":"pentoxifylline","score":0.9380000233650208},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.8679999709129333},{"id":"https://openalex.org/keywords/olanzapine","display_name":"olanzapine","score":0.8650000095367432},{"id":"https://openalex.org/keywords/atypical-trigeminal-neuralgia","display_name":"atypical trigeminal neuralgia","score":0.7770000100135803},{"id":"https://openalex.org/keywords/misdiagnosis","display_name":"misdiagnosis","score":0.6299999952316284},{"id":"https://openalex.org/keywords/headache-classification","display_name":"headache classification","score":0.6240000128746033},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.5979999899864197},{"id":"https://openalex.org/keywords/obsessive-compulsive-symptoms","display_name":"obsessive-compulsive symptoms","score":0.6240000128746033},{"id":"https://openalex.org/keywords/panic-attacks","display_name":"panic attacks","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.928099513053894},{"id":"https://openalex.org/C2779974317","wikidata":"https://www.wikidata.org/wiki/Q2003151","display_name":"Livedo reticularis","level":3,"score":0.8988561630249023},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4706553518772125},{"id":"https://openalex.org/C2779253243","wikidata":"https://www.wikidata.org/wiki/Q410412","display_name":"Carbamazepine","level":3,"score":0.4442596137523651},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.4375174343585968},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3832568824291229},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3098025918006897},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2363230586051941},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.13200756907463074},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.11544018983840942}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006261","descriptor_name":"Headache","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006261","descriptor_name":"Headache","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018860","descriptor_name":"Sneddon Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D018860","descriptor_name":"Sneddon Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10194-009-0109-3","doi":"https://doi.org/10.1007/s10194-009-0109-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10194-009-0109-3","pdf_url":"https://thejournalofheadacheandpain.biomedcentral.com/counter/pdf/10.1007/s10194-009-0109-3","source":{"id":"https://openalex.org/S143427143","display_name":"The Journal of Headache and Pain","issn_l":"1129-2369","issn":["1129-2369","1129-2377"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Headache and Pain","raw_type":"journal-article"},{"id":"pmid:19288055","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19288055","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of headache and pain","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:3451989","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3451989/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Headache Pain","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s10194-009-0109-3","doi":"https://doi.org/10.1007/s10194-009-0109-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10194-009-0109-3","pdf_url":"https://thejournalofheadacheandpain.biomedcentral.com/counter/pdf/10.1007/s10194-009-0109-3","source":{"id":"https://openalex.org/S143427143","display_name":"The Journal of Headache and Pain","issn_l":"1129-2369","issn":["1129-2369","1129-2377"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Headache and Pain","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2120902205.pdf","grobid_xml":"https://content.openalex.org/works/W2120902205.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W1984107894","https://openalex.org/W2015615388","https://openalex.org/W2023755444","https://openalex.org/W2032666115","https://openalex.org/W2073389642","https://openalex.org/W4247292047"],"related_works":["https://openalex.org/W2265008006","https://openalex.org/W2056764506","https://openalex.org/W2473390918","https://openalex.org/W2129610919","https://openalex.org/W42370640","https://openalex.org/W2295047667","https://openalex.org/W2612839603","https://openalex.org/W98333391","https://openalex.org/W4389786091","https://openalex.org/W4255445273"],"abstract_inverted_index":{"Sneddon's":[0,120,196],"syndrome":[1,28,197],"is":[2],"a":[3,42,47,51,142,170],"rare":[4],"vascular":[5],"disease":[6],"affecting":[7],"mainly":[8],"skin":[9],"and":[10,32,79,97,103,114,137,165,198,204],"brain":[11],"arterioles":[12],"leading":[13],"to":[14,18,76,88,185],"their":[15],"occlusion":[16],"due":[17],"excessive":[19],"endothelial":[20],"proliferation.":[21],"The":[22,66],"two":[23],"main":[24],"features":[25],"of":[26,41,50,145,150,181,195,201],"this":[27,175],"are":[29],"livedo":[30,99],"reticularis":[31],"lacunar":[33],"subcortical":[34],"infarcts.":[35],"Here,":[36],"we":[37,177,190],"describe":[38,191],"the":[39,148,155,179],"case":[40],"64-year-old":[43],"woman":[44],"presenting":[45],"with":[46,57,92,147],"4-year":[48],"history":[49],"throbbing,":[52],"bilateral,":[53],"parieto-occipital":[54],"headache":[55,83,183],"associated":[56],"facial":[58],"pain,":[59,67],"but":[60],"without":[61],"any":[62],"other":[63,115],"accompanying":[64],"symptom.":[65],"initially":[68],"misdiagnosed":[69],"as":[70],"atypical":[71,193],"trigeminal":[72],"neuralgia,":[73],"worsened":[74],"up":[75],"chronic":[77],"daily":[78],"such":[80],"severely":[81],"disabling":[82],"that":[84],"she":[85],"was":[86,135,158],"constrained":[87],"bed.":[89],"She":[90],"presented":[91],"reduced":[93,125],"cognitive":[94],"functions,":[95],"diffuse":[96],"severe":[98,101],"reticularis,":[100],"myalgias":[102],"mild":[104],"stiffness.":[105],"All":[106],"diagnostic":[107,187],"test":[108],"for":[109,119,169],"different":[110],"diseases":[111,116],"were":[112,124],"performed":[113],"excluded":[117],"except":[118],"syndrome.":[121],"Her":[122,152],"symptoms":[123,146],"firstly":[126],"using":[127,172,182,202],"acetylsalicylic":[128],"acid,":[129],"then":[130,138],"ticlopidine":[131,203],"250":[132],"mg":[133],"bid":[134],"begun":[136],"Pentoxyphillin,":[139],"resulting":[140],"in":[141,154],"significant":[143],"improvement":[144],"disappearance":[149],"headache.":[151],"worsening":[153],"first":[156],"year":[157],"characterized":[159],"by":[160],"obsessive-compulsive":[161],"behaviours,":[162],"body-image":[163],"misperceptions":[164],"panic":[166],"attacks,":[167],"improved":[168],"period":[171],"olanzapine.":[173],"Considering":[174],"case,":[176],"remark":[178],"importance":[180],"classification":[184],"avoid":[186],"errors,":[188],"secondly,":[189],"an":[192],"manifestation":[194],"therapeutic":[199],"efficacy":[200],"pentoxyphillin.":[205]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}