{"id":"https://openalex.org/W2120779527","doi":"https://doi.org/10.1016/s0003-4975(03)01604-7","title":"Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest","display_name":"Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest","publication_year":2004,"publication_date":"2004-01-28","ids":{"openalex":"https://openalex.org/W2120779527","doi":"https://doi.org/10.1016/s0003-4975(03)01604-7","mag":"2120779527","pmid":"https://pubmed.ncbi.nlm.nih.gov/14759455"},"language":"en","primary_location":{"id":"doi:10.1016/s0003-4975(03)01604-7","doi":"https://doi.org/10.1016/s0003-4975(03)01604-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0003-4975(03)01604-7","pdf_url":null,"source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090350376","display_name":"Oliver Klass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oliver Klass","raw_affiliation_strings":["Department of Cardiothoracic Surgery, University of Cologne, Cologne, Germany","Department of Cardiothoracic Surgery, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]},{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Cologne, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104308922","display_name":"Uwe M Fischer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Uwe M Fischer","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Cologne, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Elisabeth Perez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elisabeth Perez","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Cologne, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059699661","display_name":"Jerry Easo","orcid":"https://orcid.org/0000-0001-9445-5716","observed_orcids":["https://orcid.org/0000-0001-9445-5716"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jerry Easo","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Cologne, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091767956","display_name":"Marfalda Bosse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marfalda Bosse","raw_affiliation_strings":["Department of Experimental Medicine, University of Cologne, Cologne, Germany","#N#        Department of Experimental Medicine, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]},{"raw_affiliation_string":"#N#        Department of Experimental Medicine, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105274751","display_name":"Juergen H. Fischer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Juergen H Fischer","raw_affiliation_strings":["Department of Experimental Medicine, University of Cologne, Cologne, Germany","#N#        Department of Experimental Medicine, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]},{"raw_affiliation_string":"#N#        Department of Experimental Medicine, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058308010","display_name":"Paschalis Tossios","orcid":"https://orcid.org/0000-0002-3822-948X","observed_orcids":["https://orcid.org/0000-0002-3822-948X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paschalis Tossios","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Cologne, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080117829","display_name":"Uwe Mehlhorn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Uwe Mehlhorn","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Cologne, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080117829"],"corresponding_institution_ids":[],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":1.2377,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.80964103,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"77","issue":"2","first_page":"658","last_page":"663"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.05979999899864197,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/na-h-exchange-inhibition","display_name":"Na+/H+ exchange inhibition","score":0.9369999766349792},{"id":"https://openalex.org/keywords/cardioplegic-arrest","display_name":"cardioplegic arrest","score":0.9380000233650208},{"id":"https://openalex.org/keywords/myocardial-ischemia-reperfusion-injury","display_name":"myocardial ischemia-reperfusion injury","score":0.8330000042915344},{"id":"https://openalex.org/keywords/high-energy-phosphates","display_name":"high-energy phosphates","score":0.9160000085830688},{"id":"https://openalex.org/keywords/cardiac-function","display_name":"cardiac function","score":0.7549999952316284},{"id":"https://openalex.org/keywords/cardiopulmonary-bypass","display_name":"cardiopulmonary bypass","score":0.7850000262260437},{"id":"https://openalex.org/keywords/left-ventricular-relaxation","display_name":"left ventricular relaxation","score":0.6660000085830688},{"id":"https://openalex.org/keywords/glycogen","display_name":"glycogen","score":0.6129999756813049},{"id":"https://openalex.org/keywords/pigs","display_name":"pigs","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8334322571754456},{"id":"https://openalex.org/C48277249","wikidata":"https://www.wikidata.org/wiki/Q1406926","display_name":"Preload","level":3,"score":0.7221972942352295},{"id":"https://openalex.org/C2778881276","wikidata":"https://www.wikidata.org/wiki/Q552304","display_name":"Cardiopulmonary bypass","level":2,"score":0.6318343877792358},{"id":"https://openalex.org/C2775938633","wikidata":"https://www.wikidata.org/wiki/Q7562206","display_name":"Sonomicrometry","level":3,"score":0.5254154205322266},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.5151807069778442},{"id":"https://openalex.org/C2994266630","wikidata":"https://www.wikidata.org/wiki/Q424021","display_name":"Adenine nucleotide","level":4,"score":0.49607929587364197},{"id":"https://openalex.org/C31861589","wikidata":"https://www.wikidata.org/wiki/Q618068","display_name":"Cardiac index","level":4,"score":0.49343982338905334},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.48654475808143616},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4739782214164734},{"id":"https://openalex.org/C2778273184","wikidata":"https://www.wikidata.org/wiki/Q5365852","display_name":"High-energy phosphate","level":4,"score":0.4532907009124756},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4469505846500397},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.42812108993530273},{"id":"https://openalex.org/C2779676291","wikidata":"https://www.wikidata.org/wiki/Q25325349","display_name":"Cardioprotection","level":3,"score":0.41493356227874756},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.39991098642349243},{"id":"https://openalex.org/C2778626300","wikidata":"https://www.wikidata.org/wiki/Q1984607","display_name":"Phosphocreatine","level":3,"score":0.3288806676864624},{"id":"https://openalex.org/C2986317502","wikidata":"https://www.wikidata.org/wiki/Q570714","display_name":"Energy metabolism","level":2,"score":0.14992401003837585},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.12166830897331238},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09997457265853882},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08960065245628357},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000227","descriptor_name":"Adenine Nucleotides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002315","descriptor_name":"Cardiopulmonary Bypass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006003","descriptor_name":"Glycogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006146","descriptor_name":"Guanidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006324","descriptor_name":"Heart Arrest, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011292","descriptor_name":"Premedication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013450","descriptor_name":"Sulfones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014882","descriptor_name":"Water-Electrolyte Balance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015428","descriptor_name":"Myocardial Reperfusion Injury","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017923","descriptor_name":"Sodium-Hydrogen Exchangers","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0003-4975(03)01604-7","doi":"https://doi.org/10.1016/s0003-4975(03)01604-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0003-4975(03)01604-7","pdf_url":null,"source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},{"id":"pmid:14759455","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14759455","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of thoracic surgery","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1509551118","https://openalex.org/W1965024236","https://openalex.org/W1967233060","https://openalex.org/W1984585666","https://openalex.org/W1986888244","https://openalex.org/W1988291158","https://openalex.org/W1992856211","https://openalex.org/W1995576492","https://openalex.org/W2001468299","https://openalex.org/W2019158319","https://openalex.org/W2028982689","https://openalex.org/W2039855931","https://openalex.org/W2040871746","https://openalex.org/W2041774166","https://openalex.org/W2051563734","https://openalex.org/W2072405920","https://openalex.org/W2090593025","https://openalex.org/W2091734084","https://openalex.org/W2109979610","https://openalex.org/W2111329804","https://openalex.org/W2113950363","https://openalex.org/W2127063103","https://openalex.org/W2130413670","https://openalex.org/W2165592782","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2019158319","https://openalex.org/W2109979610","https://openalex.org/W4236469519","https://openalex.org/W2119615860","https://openalex.org/W2050498921","https://openalex.org/W2004573733","https://openalex.org/W1967500961","https://openalex.org/W2063059236","https://openalex.org/W2024561176","https://openalex.org/W2088957010"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}