{"id":"https://openalex.org/W2120774702","doi":"https://doi.org/10.1530/eje.1.02170","title":"Expression of adrenomedullin in adipose tissue of lean and obese women","display_name":"Expression of adrenomedullin in adipose tissue of lean and obese women","publication_year":2006,"publication_date":"2006-06-22","ids":{"openalex":"https://openalex.org/W2120774702","doi":"https://doi.org/10.1530/eje.1.02170","mag":"2120774702","pmid":"https://pubmed.ncbi.nlm.nih.gov/16793965"},"language":"en","primary_location":{"id":"doi:10.1530/eje.1.02170","doi":"https://doi.org/10.1530/eje.1.02170","is_oa":false,"landing_page_url":"https://doi.org/10.1530/eje.1.02170","pdf_url":null,"source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066272438","display_name":"Odile Paulmyer\u2010Lacroix","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"O Paulmyer-Lacroix","raw_affiliation_strings":["Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France. odile.lacroix-paulmyer@mail.ap-hm.fr","Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France. odile.lacroix-paulmyer@mail.ap-hm.fr","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062343791","display_name":"Raoul Desbri\u00e8re","orcid":"https://orcid.org/0000-0001-7783-1943","observed_orcids":["https://orcid.org/0000-0001-7783-1943"]},"institutions":[{"id":"https://openalex.org/I4210087487","display_name":"Assistance Publique H\u00f4pitaux de Marseille","ror":"https://ror.org/002cp4060","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087487"]},{"id":"https://openalex.org/I4210115034","display_name":"H\u00f4pital Nord","ror":"https://ror.org/029a4pp87","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210115034"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"R Desbriere","raw_affiliation_strings":["Department of Gynecology, Assistance Publique \u2013 H\u00f4pitaux de Marseille, CHU Nord, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Assistance Publique \u2013 H\u00f4pitaux de Marseille, CHU Nord, France","institution_ids":["https://openalex.org/I4210087487","https://openalex.org/I4210115034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048855731","display_name":"Marjorie Poggi","orcid":"https://orcid.org/0000-0001-6331-9682","observed_orcids":["https://orcid.org/0000-0001-6331-9682"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M Poggi","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015905263","display_name":"Vincent Achard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"V Achard","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011464147","display_name":"Marie\u2010Christine Alessi","orcid":"https://orcid.org/0000-0003-3927-5792","observed_orcids":["https://orcid.org/0000-0003-3927-5792"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M-C Alessi","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085593167","display_name":"Fran\u00e7oise Boudouresque","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Boudouresque","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm EMI 0359, Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm EMI 0359, Marseille, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045881672","display_name":"L\u2019Houcine Ouafik","orcid":"https://orcid.org/0000-0002-4848-1232","observed_orcids":["https://orcid.org/0000-0002-4848-1232"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L\u2019H Ouafik","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm EMI 0359, Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm EMI 0359, Marseille, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028752254","display_name":"Vincent Vuaroqueaux","orcid":"https://orcid.org/0000-0001-9120-5332","observed_orcids":["https://orcid.org/0000-0001-9120-5332"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Vuaroqueaux","raw_affiliation_strings":["OncoScore AG, Riehen, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OncoScore AG, Riehen, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057279232","display_name":"Martin Labuhn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Labuhn","raw_affiliation_strings":["OncoScore AG, Riehen, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OncoScore AG, Riehen, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"A Dutourand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A Dutourand","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047054369","display_name":"Michel Grino","orcid":"https://orcid.org/0000-0001-6487-774X","observed_orcids":["https://orcid.org/0000-0001-6487-774X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405264361","display_name":"Universit\u00e9 de la M\u00e9diterran\u00e9e Aix-Marseille II","ror":"https://ror.org/01q1nds63","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767","https://openalex.org/I4405264361"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M Grino","raw_affiliation_strings":["Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universit\u00e9 de la M\u00e9diterran\u00e9e, Aix-Marseille II, France","institution_ids":["https://openalex.org/I4405264361"]},{"raw_affiliation_string":"Inserm UMR 626, UFR de M\u00e9decine secteur Timone, 27 Bd Jean Moulin, 13385 Marseille cedex 5, France","institution_ids":["https://openalex.org/I154526488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5066272438"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4405264361"],"apc_list":{"value":3798,"currency":"EUR","value_usd":4292},"apc_paid":null,"fwci":1.993,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.86902468,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"155","issue":"1","first_page":"177","last_page":"185"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adrenomedullin","display_name":"adrenomedullin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.9900000095367432},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9850000143051147},{"id":"https://openalex.org/keywords/omental-adipose-tissue","display_name":"omental adipose tissue","score":0.9150000214576721},{"id":"https://openalex.org/keywords/subcutaneous-adipose-tissue","display_name":"subcutaneous adipose tissue","score":0.9940000176429749},{"id":"https://openalex.org/keywords/adipose-stromal-cells","display_name":"adipose stromal cells","score":0.890999972820282},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.5419999957084656},{"id":"https://openalex.org/keywords/calcitonin-receptor-like-receptor","display_name":"calcitonin receptor-like receptor","score":0.8600000143051147},{"id":"https://openalex.org/keywords/ramp2","display_name":"RAMP2","score":0.8840000033378601},{"id":"https://openalex.org/keywords/ramp3","display_name":"RAMP3","score":1.0},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9599999785423279},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.9459999799728394},{"id":"https://openalex.org/keywords/preadipocyte-differentiation","display_name":"preadipocyte differentiation","score":0.7059999704360962},{"id":"https://openalex.org/keywords/vasodilator-peptides","display_name":"vasodilator peptides","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.9426933526992798},{"id":"https://openalex.org/C17675752","wikidata":"https://www.wikidata.org/wiki/Q12898553","display_name":"Adipose tissue macrophages","level":4,"score":0.8092901110649109},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7856605052947998},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7609517574310303},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.7255676984786987},{"id":"https://openalex.org/C2777152744","wikidata":"https://www.wikidata.org/wiki/Q366935","display_name":"Adrenomedullin","level":3,"score":0.6848770380020142},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.6685054302215576},{"id":"https://openalex.org/C151955695","wikidata":"https://www.wikidata.org/wiki/Q654528","display_name":"White adipose tissue","level":3,"score":0.5571926832199097},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5404942631721497},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4392920732498169},{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.4161006808280945},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32399100065231323},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25916481018066406}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000886","descriptor_name":"Anthropometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001774","descriptor_name":"Blood Chemical Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017403","descriptor_name":"In Situ Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053607","descriptor_name":"Adrenomedullin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1530/eje.1.02170","doi":"https://doi.org/10.1530/eje.1.02170","is_oa":false,"landing_page_url":"https://doi.org/10.1530/eje.1.02170","pdf_url":null,"source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Endocrinology","raw_type":"journal-article"},{"id":"pmid:16793965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16793965","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.332.8219","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.332.8219","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.eje-online.org/content/155/1/177.full.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:hal-01823883v1","doi":null,"is_oa":false,"landing_page_url":"https://amu.hal.science/hal-01823883","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Endocrinology, 2006, 155 (1), pp.177 - 185. ⟨10.1530/eje.1.02170⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W292647304","https://openalex.org/W1864871585","https://openalex.org/W1969305721","https://openalex.org/W1969389801","https://openalex.org/W1977944810","https://openalex.org/W1981492597","https://openalex.org/W1984344570","https://openalex.org/W1987183678","https://openalex.org/W1991079474","https://openalex.org/W1996865419","https://openalex.org/W2001676064","https://openalex.org/W2014765190","https://openalex.org/W2018298970","https://openalex.org/W2023541036","https://openalex.org/W2034270204","https://openalex.org/W2037386031","https://openalex.org/W2041920734","https://openalex.org/W2042107619","https://openalex.org/W2046572176","https://openalex.org/W2046787212","https://openalex.org/W2051372947","https://openalex.org/W2061512981","https://openalex.org/W2062692217","https://openalex.org/W2073796511","https://openalex.org/W2092419989","https://openalex.org/W2092491118","https://openalex.org/W2102009612","https://openalex.org/W2115774683","https://openalex.org/W2119121134","https://openalex.org/W2121201077","https://openalex.org/W2121353747","https://openalex.org/W2123992393","https://openalex.org/W2129334057","https://openalex.org/W2146664412","https://openalex.org/W2152948578","https://openalex.org/W2159622967","https://openalex.org/W2160234571","https://openalex.org/W2163005238","https://openalex.org/W2473495692"],"related_works":["https://openalex.org/W7097609127","https://openalex.org/W2067801294","https://openalex.org/W1987183678","https://openalex.org/W2066377469","https://openalex.org/W2981824160","https://openalex.org/W2626511264","https://openalex.org/W2037386031","https://openalex.org/W1968188989","https://openalex.org/W2065995205","https://openalex.org/W2124989143"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Adrenomedullin":[1],"(AM),":[2],"a":[3,192,252],"potent":[4],"vasodilatator":[5],"and":[6,35,45,53,70,86,102,122,128,155,169,198,205,238],"antioxidative":[7],"peptide,":[8],"was":[9,23,79,94,151],"shown":[10],"recently":[11],"to":[12,24,36],"be":[13,249],"expressed":[14,132],"by":[15,81],"adipose":[16,33,48,66,157,223],"tissue.":[17,158],"The":[18],"aim":[19],"of":[20,29,107,139,214,242,255],"our":[21],"study":[22],"investigate":[25],"the":[26,212,215,233,240,243,256],"precise":[27],"localization":[28,150],"AM":[30,38,60,77,92,149,159,174,197,247],"within":[31],"human":[32,65,222],"tissue,":[34,224],"examine":[37],"regulation":[39],"in":[40,83,96,133,148,161,176,182,208,232],"obesity.":[41],"DESIGN:":[42],"Subcutaneous":[43],"(SC)":[44],"omental":[46],"(OM)":[47],"tissues":[49],"from":[50,64,221],"9":[51],"lean":[52,168,187],"13":[54],"obese":[55,170,183],"women":[56],"were":[57,68,116,131,179],"profiled":[58],"for":[59],"expression":[61,78,93],"changes.":[62],"Preadipocytes":[63],"tissue":[67,163,178,210],"isolated":[69,103],"differentiated":[71],"under":[72],"defined":[73],"adipogenic":[74],"conditions.":[75],"METHODS:":[76],"analyzed":[80],"immunohistochemistry,":[82],"situ":[84],"hybridization":[85],"quantitative":[87],"RT-PCR.":[88],"RESULTS:":[89],"A":[90],"strong":[91],"observed":[95],"vessel":[97,134],"walls,":[98],"stromal":[99,104],"cell":[100],"clusters":[101],"cells,":[105],"some":[106],"them":[108],"being":[109],"CD":[110],"68":[111],"positive,":[112],"whereas":[113],"mature":[114],"adipocytes":[115],"not":[117,165],"labeled.":[118],"Calcitonin":[119],"receptor-like":[120],"receptor":[121,123],"activity-modifying":[124],"proteins":[125],"(RAMP)":[126],"2":[127],"RAMP":[129],"3":[130],"walls.":[135],"In":[136],"vitro,":[137],"preadipocytes":[138],"early":[140],"differentiation":[141],"stages":[142],"spontaneously":[143],"secreted":[144],"AM.":[145,228],"No":[146],"difference":[147],"found":[152,191],"between":[153,167,195],"SC":[154,162],"OM":[156,177,196,209,234],"levels":[160,175,204],"did":[164],"differ":[166],"subjects.":[171],"By":[172],"contrast,":[173],"significantly":[180],"higher":[181],"as":[184,251],"compared":[185],"with":[186],"women.":[188],"Moreover,":[189],"we":[190],"positive":[193],"relationship":[194],"tumor":[199],"necrosis":[200],"factor":[201],"alpha":[202],"mRNA":[203],"AM-immunoreactive":[206],"area":[207],"followed":[211],"features":[213,241],"metabolic":[216,244],"syndrome.":[217,245],"CONCLUSION:":[218],"Stromal":[219],"cells":[220],"including":[225],"macrophages,":[226],"produce":[227],"Its":[229],"synthesis":[230],"increased":[231],"territory":[235],"during":[236],"obesity":[237],"paralleled":[239],"Therefore,":[246],"should":[248],"considered":[250],"new":[253],"member":[254],"adipokine":[257],"family.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}