{"id":"https://openalex.org/W2120622011","doi":null,"title":"Multiple malaria infection in a pregnant woman from Nigeria: detection by multiplex PCR.","display_name":"Multiple malaria infection in a pregnant woman from Nigeria: detection by multiplex PCR.","publication_year":2008,"publication_date":"2008-10-01","ids":{"openalex":"https://openalex.org/W2120622011","mag":"2120622011","pmid":"https://pubmed.ncbi.nlm.nih.gov/19123315"},"language":"en","primary_location":{"id":"pmid:19123315","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19123315","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The new microbiologica","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016734890","display_name":"Rosalia Graffeo","orcid":"https://orcid.org/0009-0003-3608-3573","observed_orcids":["https://orcid.org/0009-0003-3608-3573"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosalia Graffeo","raw_affiliation_strings":["Institute of Microbiology, Catholic University of the Sacred Heart, Rome, Italy. liagrafit@yahoo.it"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microbiology, Catholic University of the Sacred Heart, Rome, Italy. liagrafit@yahoo.it","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021409727","display_name":"Luca Masucci","orcid":"https://orcid.org/0000-0002-8358-6726","observed_orcids":["https://orcid.org/0000-0002-8358-6726"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luca Masucci","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078766693","display_name":"Francesca Bugli","orcid":"https://orcid.org/0000-0001-9038-3233","observed_orcids":["https://orcid.org/0000-0001-9038-3233"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francesca Bugli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110479621","display_name":"Fernando Damiano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fernando Damiano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Carmen Pinnetti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carmen Pinnetti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002638989","display_name":"Giovanni Federico","orcid":"https://orcid.org/0000-0003-4604-5426","observed_orcids":["https://orcid.org/0000-0003-4604-5426"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanni Federico","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103425238","display_name":"Giovanni Fadda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanni Fadda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6825,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.77196803,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"31","issue":"4","first_page":"565","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12178","display_name":"Bird parasitology and diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malaria","display_name":"malaria","score":0.6520000100135803},{"id":"https://openalex.org/keywords/mixed-malaria-infection","display_name":"mixed malaria infection","score":0.8379999995231628},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.9459999799728394},{"id":"https://openalex.org/keywords/plasmodium-vivax","display_name":"Plasmodium vivax","score":0.9929999709129333},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.675000011920929},{"id":"https://openalex.org/keywords/multiplex-pcr","display_name":"multiplex PCR","score":0.9139999747276306},{"id":"https://openalex.org/keywords/rapid-diagnostic-tests","display_name":"rapid diagnostic tests","score":0.7360000014305115},{"id":"https://openalex.org/keywords/giemsa-stained-blood-films","display_name":"Giemsa-stained blood films","score":0.7379999756813049},{"id":"https://openalex.org/keywords/parasite-species-identification","display_name":"parasite species identification","score":0.6650000214576721},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.8859999775886536}],"concepts":[{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.8377598524093628},{"id":"https://openalex.org/C154488023","wikidata":"https://www.wikidata.org/wiki/Q1412684","display_name":"Giemsa stain","level":2,"score":0.787261962890625},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.623799741268158},{"id":"https://openalex.org/C3017819844","wikidata":"https://www.wikidata.org/wiki/Q886475","display_name":"Blood smear","level":3,"score":0.618828535079956},{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.6127763986587524},{"id":"https://openalex.org/C3018882108","wikidata":"https://www.wikidata.org/wiki/Q886475","display_name":"Blood film","level":3,"score":0.603657603263855},{"id":"https://openalex.org/C2779810223","wikidata":"https://www.wikidata.org/wiki/Q5270339","display_name":"Diagnosis of malaria","level":4,"score":0.5808137059211731},{"id":"https://openalex.org/C90583042","wikidata":"https://www.wikidata.org/wiki/Q1952456","display_name":"Multiplex polymerase chain reaction","level":4,"score":0.5445131063461304},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4816552400588989},{"id":"https://openalex.org/C2779997623","wikidata":"https://www.wikidata.org/wiki/Q311376","display_name":"Plasmodium vivax","level":4,"score":0.48139169812202454},{"id":"https://openalex.org/C2778675580","wikidata":"https://www.wikidata.org/wiki/Q614956","display_name":"Plasmodium (life cycle)","level":3,"score":0.4750537872314453},{"id":"https://openalex.org/C71928629","wikidata":"https://www.wikidata.org/wiki/Q804206","display_name":"Parasite hosting","level":2,"score":0.47372546792030334},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4550042152404785},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4520806670188904},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4499186873435974},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.38824784755706787},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32937949895858765},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.3019263744354248},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.14916038513183594},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.059663623571395874},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05710035562515259},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D009549","descriptor_name":"Nigeria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010961","descriptor_name":"Plasmodium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010961","descriptor_name":"Plasmodium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015597","descriptor_name":"Pregnancy Complications, Parasitic","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D016054","descriptor_name":"DNA, Protozoan","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:19123315","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19123315","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The new microbiologica","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1977784023","https://openalex.org/W2003741250","https://openalex.org/W2020928512","https://openalex.org/W2048126647","https://openalex.org/W2105765568","https://openalex.org/W2108522714","https://openalex.org/W2169913483"],"related_works":["https://openalex.org/W4406608063","https://openalex.org/W2399484661","https://openalex.org/W2097681192","https://openalex.org/W2031653118","https://openalex.org/W2078103267","https://openalex.org/W1575650847","https://openalex.org/W3012903285","https://openalex.org/W7051819697","https://openalex.org/W1655808485","https://openalex.org/W2010079063"],"abstract_inverted_index":{"For":[0],"the":[1,21,34,69,76,99],"last":[2],"100":[3],"years,":[4],"diagnosis":[5],"of":[6,13,47],"malaria":[7],"has":[8,113],"been":[9],"based":[10],"on":[11],"examination":[12],"Giemsa-stained":[14],"thick":[15],"and":[16,63,105,110,120],"thin":[17],"blood":[18,45],"films":[19],"under":[20],"microscope.":[22],"This":[23],"is":[24,102],"a":[25,90],"time-consuming":[26],"procedure":[27],"which":[28],"often":[29],"fails":[30],"to":[31,84,118],"correctly":[32],"diagnose":[33],"infecting":[35],"species--especially":[36],"when":[37,44],"carried":[38],"out":[39],"by":[40],"inexperienced":[41],"technicians":[42],"or":[43],"levels":[46],"parasite":[48],"are":[49],"low.":[50],"Rapid":[51],"Diagnostic":[52],"Tests":[53],"(RDTs)":[54],"for":[55],"antigen":[56],"detection":[57],"can":[58,106],"distinguish":[59],"between":[60],"Plasmodium":[61,64],"falciparum":[62],"vivax":[65],"but":[66],"cannot":[67],"identify":[68],"species":[70],"present":[71],"in":[72,89],"mixed":[73,87],"infections.":[74],"In":[75],"case":[77],"reported":[78],"here":[79],"we":[80],"used":[81,101],"multiplex":[82],"PCR":[83],"investigate":[85],"suspected":[86],"infection":[88],"pregnant":[91],"woman":[92],"from":[93],"Nigeria.":[94],"The":[95],"results":[96],"suggest":[97],"that":[98,111],"method":[100],"highly":[103],"specific":[104],"be":[107],"very":[108],"sensitive":[109],"it":[112],"several":[114],"advantages":[115],"with":[116],"respect":[117],"microscopy":[119],"RTDs.":[121]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}