{"id":"https://openalex.org/W2119454792","doi":"https://doi.org/10.1371/journal.pone.0035398","title":"Examining the Fish Microbiome: Vertebrate-Derived Bacteria as an Environmental Niche for the Discovery of Unique Marine Natural Products","display_name":"Examining the Fish Microbiome: Vertebrate-Derived Bacteria as an Environmental Niche for the Discovery of Unique Marine Natural Products","publication_year":2012,"publication_date":"2012-05-04","ids":{"openalex":"https://openalex.org/W2119454792","doi":"https://doi.org/10.1371/journal.pone.0035398","mag":"2119454792","pmid":"https://pubmed.ncbi.nlm.nih.gov/22574119","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3344833"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0035398","doi":"https://doi.org/10.1371/journal.pone.0035398","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0035398","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035398&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035398&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024294799","display_name":"Laura M. Sanchez","orcid":"https://orcid.org/0000-0001-9223-7977","observed_orcids":["https://orcid.org/0000-0001-9223-7977"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura M. Sanchez","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031608153","display_name":"Weng Ruh Wong","orcid":"https://orcid.org/0000-0002-2940-7344","observed_orcids":["https://orcid.org/0000-0002-2940-7344"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weng Ruh Wong","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022698692","display_name":"Romina M. Riener","orcid":"https://orcid.org/0000-0001-5005-112X","observed_orcids":["https://orcid.org/0000-0001-5005-112X"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Romina M. Riener","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052945974","display_name":"Christopher J. Schulze","orcid":"https://orcid.org/0009-0005-6736-871X","observed_orcids":["https://orcid.org/0009-0005-6736-871X"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Schulze","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015133560","display_name":"Roger G. Linington","orcid":"https://orcid.org/0000-0003-1818-4971","observed_orcids":["https://orcid.org/0000-0003-1818-4971"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Roger G. Linington","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America","institution_ids":["https://openalex.org/I185103710"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5015133560"],"corresponding_institution_ids":["https://openalex.org/I185103710"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":2.9387,"has_fulltext":true,"cited_by_count":99,"citation_normalized_percentile":{"value":0.90638652,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"7","issue":"5","first_page":"e35398","last_page":"e35398"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.8339999914169312,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.8339999914169312,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":0.1581999957561493,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fish-microbiome","display_name":"fish microbiome","score":0.9940000176429749},{"id":"https://openalex.org/keywords/fish-intestinal-bacteria","display_name":"fish intestinal bacteria","score":0.7129999995231628},{"id":"https://openalex.org/keywords/marine-natural-products","display_name":"marine natural products","score":0.8870000243186951},{"id":"https://openalex.org/keywords/marine-actinomycetes","display_name":"marine actinomycetes","score":0.8090000152587891},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/fish-pathogens","display_name":"fish pathogens","score":0.6850000023841858},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.8690000176429749},{"id":"https://openalex.org/keywords/vibrio-mimicus","display_name":"Vibrio mimicus","score":0.9490000009536743},{"id":"https://openalex.org/keywords/enterococcus-faecium","display_name":"Enterococcus faecium","score":0.8650000095367432},{"id":"https://openalex.org/keywords/bacillus-subtilis","display_name":"Bacillus subtilis","score":0.949999988079071},{"id":"https://openalex.org/keywords/novel-bacterial-isolates","display_name":"novel bacterial isolates","score":0.3019999861717224}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8445963859558105},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.7750138640403748},{"id":"https://openalex.org/C2778169975","wikidata":"https://www.wikidata.org/wiki/Q130914","display_name":"Actinobacteria","level":4,"score":0.7075292468070984},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.5724784135818481},{"id":"https://openalex.org/C2777695942","wikidata":"https://www.wikidata.org/wiki/Q149075","display_name":"Firmicutes","level":4,"score":0.5498067736625671},{"id":"https://openalex.org/C190944805","wikidata":"https://www.wikidata.org/wiki/Q3922751","display_name":"Human Microbiome Project","level":4,"score":0.5281950235366821},{"id":"https://openalex.org/C2776154503","wikidata":"https://www.wikidata.org/wiki/Q753490","display_name":"Vibrio","level":3,"score":0.4608265161514282},{"id":"https://openalex.org/C175605896","wikidata":"https://www.wikidata.org/wiki/Q39833","display_name":"Microorganism","level":3,"score":0.4307363033294678},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.3947335481643677},{"id":"https://openalex.org/C91478284","wikidata":"https://www.wikidata.org/wiki/Q6623796","display_name":"Human microbiome","level":3,"score":0.36968034505844116},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.26226556301116943},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12771472334861755},{"id":"https://openalex.org/C42062724","wikidata":"https://www.wikidata.org/wiki/Q1209205","display_name":"16S ribosomal RNA","level":3,"score":0.09792107343673706},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07566127181053162}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005399","descriptor_name":"Fishes","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009792","descriptor_name":"Oceans and Seas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044822","descriptor_name":"Biodiversity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046508","descriptor_name":"Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pone.0035398","doi":"https://doi.org/10.1371/journal.pone.0035398","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0035398","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035398&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2354218","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3344833","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3344833","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3344833","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:22574119","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22574119","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.270.3269","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.270.3269","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/73/68/PLoS_One_2012_May_4_7(5)_e35398.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:9edbe4906e124f75acb34aaa4a7da673","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9edbe4906e124f75acb34aaa4a7da673","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 7, Iss 5, p e35398 (2012)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/125435","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Examining_the_Fish_Microbiome_Vertebrate_Derived_Bacteria_as_an_Environmental_Niche_for_the_Discovery_of_Unique_Marine_Natural_Products/125435","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0035398","doi":"https://doi.org/10.1371/journal.pone.0035398","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0035398","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035398&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/14","display_name":"Life below water"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1386346227","display_name":"ICBG: \"Training, Conservation and Drug Discovery using Panamanian Microorganisms","funder_award_id":"U01TW006634","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G8538347698","display_name":null,"funder_award_id":"2R25GM05803-12","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2119454792.pdf","grobid_xml":"https://content.openalex.org/works/W2119454792.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W850294230","https://openalex.org/W1579440051","https://openalex.org/W1736575550","https://openalex.org/W1758131994","https://openalex.org/W1924759298","https://openalex.org/W1962398740","https://openalex.org/W1964300889","https://openalex.org/W1972505691","https://openalex.org/W1975759924","https://openalex.org/W1977166123","https://openalex.org/W1977739164","https://openalex.org/W1979573684","https://openalex.org/W1995622742","https://openalex.org/W1997614802","https://openalex.org/W2004379995","https://openalex.org/W2019373512","https://openalex.org/W2022309022","https://openalex.org/W2026354907","https://openalex.org/W2030966943","https://openalex.org/W2037026236","https://openalex.org/W2043399215","https://openalex.org/W2049185119","https://openalex.org/W2056381830","https://openalex.org/W2061425474","https://openalex.org/W2065461553","https://openalex.org/W2066379464","https://openalex.org/W2069794768","https://openalex.org/W2074316896","https://openalex.org/W2074478479","https://openalex.org/W2082329225","https://openalex.org/W2087726825","https://openalex.org/W2090925778","https://openalex.org/W2093445025","https://openalex.org/W2093692663","https://openalex.org/W2094985765","https://openalex.org/W2097382368","https://openalex.org/W2097393422","https://openalex.org/W2097706568","https://openalex.org/W2110105875","https://openalex.org/W2111139603","https://openalex.org/W2118124686","https://openalex.org/W2121677860","https://openalex.org/W2126809954","https://openalex.org/W2130688401","https://openalex.org/W2132632499","https://openalex.org/W2140522302","https://openalex.org/W2143214870","https://openalex.org/W2155066423","https://openalex.org/W2166265186","https://openalex.org/W2166785990","https://openalex.org/W2168599417","https://openalex.org/W2169330513","https://openalex.org/W2169942471","https://openalex.org/W2182288105","https://openalex.org/W2871048883","https://openalex.org/W4210998501","https://openalex.org/W6637742581","https://openalex.org/W7071454234"],"related_works":["https://openalex.org/W3095107488","https://openalex.org/W7036803414","https://openalex.org/W4400212584","https://openalex.org/W1982017897","https://openalex.org/W2111030972","https://openalex.org/W4411954620","https://openalex.org/W3164350300","https://openalex.org/W4403800834","https://openalex.org/W1986370322","https://openalex.org/W2002347007"],"abstract_inverted_index":{"Historically,":[0],"marine":[1,130],"invertebrates":[2],"have":[3,70,133],"been":[4],"a":[5,13,50,76,112,156],"prolific":[6],"source":[7,78],"of":[8,16,21,32,34,55,65,79,109,114,119,146,159,175,177],"unique":[9,51,99],"natural":[10,85,103],"products,":[11,104],"with":[12,98,192],"diverse":[14],"array":[15],"biological":[17],"activities.":[18],"Recent":[19],"studies":[20],"invertebrate-associated":[22],"microbial":[23,56,80,121],"communities":[24,64],"are":[25,148],"revealing":[26],"microorganisms":[27,97],"as":[28,49,75,168,170,188],"the":[29,39,46,62,72,90,93,182],"true":[30],"producers":[31],"many":[33],"these":[35,153,178],"compounds.":[36],"Inspired":[37],"by":[38],"human":[40,47,166],"microbiome":[41,95],"project,":[42],"which":[43,147],"has":[44,180],"highlighted":[45],"intestine":[48],"microenvironment":[52],"in":[53],"terms":[54],"diversity,":[57],"we":[58,69,105,132],"elected":[59],"to":[60,127],"examine":[61],"bacterial":[63],"fish":[66,73,94,110,172],"intestines":[67],"(which":[68],"termed":[71],"microbiome)":[74],"new":[77],"and":[81,116,164,201],"biosynthetic":[82],"diversity":[83],"for":[84,101,129],"products":[86],"discovery.":[87],"To":[88],"test":[89],"hypothesis":[91],"that":[92,138],"contains":[96],"capacity":[100],"biosynthesizing":[102],"examined":[106],"six":[107],"species":[108],"through":[111],"combination":[113],"dissection":[115],"culture-dependent":[117],"evaluation":[118],"intestinal":[120],"communities.":[122],"Using":[123],"isolation":[124],"media":[125],"designed":[126],"enrich":[128],"Actinobacteria,":[131],"found":[134],"three":[135],"main":[136],"clades":[137],"show":[139],"taxonomic":[140],"divergence":[141],"from":[142,152],"known":[143],"strains,":[144],"several":[145,171],"previously":[149],"uncultured.":[150],"Extracts":[151],"strains":[154],"exhibit":[155],"wide":[157],"range":[158],"activities":[160],"against":[161,194],"both":[162],"gram-positive":[163],"gram-negative":[165],"pathogens,":[167],"well":[169],"pathogens.":[173],"Exploration":[174],"one":[176],"extracts":[179],"identified":[181],"novel":[183],"bioactive":[184],"lipid":[185],"sebastenoic":[186],"acid":[187],"an":[189],"anti-microbial":[190],"agent,":[191],"activity":[193],"Staphylococcus":[195],"aureus,":[196],"Bacillus":[197],"subtilis,":[198],"Enterococcus":[199],"faecium,":[200],"Vibrio":[202],"mimicus.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}