{"id":"https://openalex.org/W2118960795","doi":"https://doi.org/10.1128/jvi.05662-11","title":"Tissue Tropism of Swine Influenza Viruses and Reassortants in Ex Vivo Cultures of the Human Respiratory Tract and Conjunctiva","display_name":"Tissue Tropism of Swine Influenza Viruses and Reassortants in Ex Vivo Cultures of the Human Respiratory Tract and Conjunctiva","publication_year":2011,"publication_date":"2011-09-01","ids":{"openalex":"https://openalex.org/W2118960795","doi":"https://doi.org/10.1128/jvi.05662-11","mag":"2118960795","pmid":"https://pubmed.ncbi.nlm.nih.gov/21880750","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3209323"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.05662-11","doi":"https://doi.org/10.1128/jvi.05662-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.05662-11","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3209323/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024050485","display_name":"Renee W. Y. Chan","orcid":"https://orcid.org/0000-0001-6485-0926","observed_orcids":["https://orcid.org/0000-0001-6485-0926","https://orcid.org/0000-0002-0682-9587"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Renee W. Y. Chan","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","Department of Pathology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"Department of Pathology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084078129","display_name":"Sara S.R. Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Sara S. R. Kang","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038296886","display_name":"Hui\u2010Ling Yen","orcid":"https://orcid.org/0000-0003-2493-3609","observed_orcids":["https://orcid.org/0000-0003-2493-3609"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Hui-Ling Yen","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","HKU-Pasteur Research Centre, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"HKU-Pasteur Research Centre, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087256369","display_name":"Alan C. L. Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Alan C. L. Li","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048915218","display_name":"Lynsia L. S. Tang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Lynsia L. S. Tang","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113668964","display_name":"Wendy C. L. Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Wendy C. L. Yu","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014169489","display_name":"Kit M. Yuen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Kit M. Yuen","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","Department of Pathology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"Department of Pathology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112138612","display_name":"Icarus W. W. Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Icarus W. W. Chan","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110918193","display_name":"Diana Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Diana D. Y. Wong","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","HKU-Pasteur Research Centre, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"HKU-Pasteur Research Centre, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109332572","display_name":"Wico W. Lai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Wico W. Lai","raw_affiliation_strings":["The Eye Institute, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Eye Institute, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111974573","display_name":"Dora L.\ufffdW. Kwong","orcid":"https://orcid.org/0000-0002-1304-2854","observed_orcids":["https://orcid.org/0000-0002-1304-2854"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Dora L. W. Kwong","raw_affiliation_strings":["Department of Clinical Oncology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Oncology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023000081","display_name":"Alan Dart Loon Sihoe","orcid":"https://orcid.org/0000-0003-3891-6180","observed_orcids":["https://orcid.org/0000-0003-3891-6180"]},"institutions":[{"id":"https://openalex.org/I2800810863","display_name":"Queen Mary Hospital","ror":"https://ror.org/02xkx3e48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I2800810863"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Alan D. L. Sihoe","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I2800810863","https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036046953","display_name":"Leo L. M. Poon","orcid":"https://orcid.org/0000-0002-9101-7953","observed_orcids":["https://orcid.org/0000-0002-9101-7953"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Leo L. M. Poon","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067201995","display_name":"Yi Guan","orcid":"https://orcid.org/0000-0001-6057-9243","observed_orcids":["https://orcid.org/0000-0001-6057-9243"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Yi Guan","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034880731","display_name":"John Malcolm Nicholls","orcid":"https://orcid.org/0000-0001-7217-7444","observed_orcids":["https://orcid.org/0000-0001-7217-7444"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"John M. Nicholls","raw_affiliation_strings":["Department of Pathology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006065098","display_name":"Malik J. S. Peiris","orcid":"https://orcid.org/0000-0001-8217-5995","observed_orcids":["https://orcid.org/0000-0001-8217-5995"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"J. S. Malik Peiris","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","HKU-Pasteur Research Centre, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"HKU-Pasteur Research Centre, Hong Kong SAR, China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046056065","display_name":"Michael C. W. Chan","orcid":"https://orcid.org/0000-0001-8174-8405","observed_orcids":["https://orcid.org/0000-0001-8174-8405"]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Michael C. W. Chan","raw_affiliation_strings":["Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I889458895"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9539,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.83482768,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"85","issue":"22","first_page":"11581","last_page":"11587"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swine-influenza-virus","display_name":"swine influenza virus","score":0.7720000147819519},{"id":"https://openalex.org/keywords/2009-h1n1-pandemic","display_name":"2009 H1N1 pandemic","score":0.8389999866485596},{"id":"https://openalex.org/keywords/reassortment","display_name":"reassortment","score":0.6320000290870667},{"id":"https://openalex.org/keywords/seasonal-h1n1","display_name":"seasonal H1N1","score":0.7160000205039978},{"id":"https://openalex.org/keywords/conjunctiva","display_name":"conjunctiva","score":0.7070000171661377},{"id":"https://openalex.org/keywords/alveolar-epithelium","display_name":"alveolar epithelium","score":0.777999997138977},{"id":"https://openalex.org/keywords/bronchial-epithelium","display_name":"bronchial epithelium","score":0.8889999985694885},{"id":"https://openalex.org/keywords/nasopharynx","display_name":"nasopharynx","score":0.7860000133514404},{"id":"https://openalex.org/keywords/neuraminidase","display_name":"neuraminidase","score":0.7940000295639038},{"id":"https://openalex.org/keywords/hemagglutinin","display_name":"hemagglutinin","score":0.9940000176429749},{"id":"https://openalex.org/keywords/pandemic-emergence","display_name":"pandemic emergence","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8667733073234558},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7986882925033569},{"id":"https://openalex.org/C35693153","wikidata":"https://www.wikidata.org/wiki/Q239762","display_name":"Tropism","level":3,"score":0.7821115255355835},{"id":"https://openalex.org/C16154277","wikidata":"https://www.wikidata.org/wiki/Q2004399","display_name":"Reassortment","level":5,"score":0.7444733381271362},{"id":"https://openalex.org/C33602714","wikidata":"https://www.wikidata.org/wiki/Q7809666","display_name":"Tissue tropism","level":4,"score":0.639490008354187},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5883312225341797},{"id":"https://openalex.org/C134164806","wikidata":"https://www.wikidata.org/wiki/Q409485","display_name":"Neuraminidase","level":3,"score":0.5660935044288635},{"id":"https://openalex.org/C2777546802","wikidata":"https://www.wikidata.org/wiki/Q834390","display_name":"Influenza A virus","level":3,"score":0.5527528524398804},{"id":"https://openalex.org/C2779644171","wikidata":"https://www.wikidata.org/wiki/Q13400765","display_name":"Respiratory tract","level":3,"score":0.4674832224845886},{"id":"https://openalex.org/C519248777","wikidata":"https://www.wikidata.org/wiki/Q160122","display_name":"Influenza A virus subtype H5N1","level":3,"score":0.44715991616249084},{"id":"https://openalex.org/C12914427","wikidata":"https://www.wikidata.org/wiki/Q7933612","display_name":"Viral shedding","level":3,"score":0.43667787313461304},{"id":"https://openalex.org/C87568996","wikidata":"https://www.wikidata.org/wiki/Q1428754","display_name":"Respiratory epithelium","level":3,"score":0.4363832473754883},{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.43502938747406006},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.42523807287216187},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.3611264228820801},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.3312796652317047},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12980881333351135},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.11773219704627991},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.10226020216941833},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.07604792714118958},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.06495866179466248},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003228","descriptor_name":"Conjunctiva","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009924","descriptor_name":"Organ Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016865","descriptor_name":"Reassortant Viruses","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D020545","descriptor_name":"Respiratory Mucosa","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D053118","descriptor_name":"Influenza A Virus, H1N1 Subtype","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053118","descriptor_name":"Influenza A Virus, H1N1 Subtype","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D053118","descriptor_name":"Influenza A Virus, H1N1 Subtype","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D056189","descriptor_name":"Viral Tropism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057221","descriptor_name":"Influenza A Virus, H1N2 Subtype","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057221","descriptor_name":"Influenza A Virus, H1N2 Subtype","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D057221","descriptor_name":"Influenza A Virus, H1N2 Subtype","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1128/jvi.05662-11","doi":"https://doi.org/10.1128/jvi.05662-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.05662-11","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmid:21880750","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21880750","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3209323","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3209323/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.655.5472","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.655.5472","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209323/pdf/zjv11581.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:pasteur-00620915v1","doi":null,"is_oa":false,"landing_page_url":"https://riip.hal.science/pasteur-00620915","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Virology, 2011, epub ahead of print. &#x27E8;10.1128/JVI.05662-11&#x27E9;","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:hub.hku.hk:10722/146789","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10722/146789","pdf_url":null,"source":{"id":"https://openalex.org/S4377196271","display_name":"The HKU Scholars Hub (University of Hong Kong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I889458895","host_organization_name":"University of Hong Kong","host_organization_lineage":["https://openalex.org/I889458895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3209323","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3209323/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1309367075","display_name":null,"funder_award_id":"HHSN266200700005C","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4476752986","display_name":null,"funder_award_id":"266200700005C","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1995003146","https://openalex.org/W2007032789","https://openalex.org/W2041753380","https://openalex.org/W2069277514","https://openalex.org/W2072237100","https://openalex.org/W2092398633","https://openalex.org/W2103215633","https://openalex.org/W2104356521","https://openalex.org/W2110990442","https://openalex.org/W2117216900","https://openalex.org/W2121009566","https://openalex.org/W2141816893","https://openalex.org/W2166309543","https://openalex.org/W2171615975","https://openalex.org/W2312463092"],"related_works":["https://openalex.org/W1992814364","https://openalex.org/W2069277514","https://openalex.org/W2102881830","https://openalex.org/W7062434388","https://openalex.org/W2160611664","https://openalex.org/W7098995117","https://openalex.org/W2281648333","https://openalex.org/W1512985734","https://openalex.org/W2147901189","https://openalex.org/W2094346042"],"abstract_inverted_index":{"The":[0],"2009":[1,79],"pandemic":[2,23,55,80],"influenza":[3,13,22,39,43,69,85,317],"H1N1":[4,81,86,123,255,276],"(H1N1pdm)":[5,82],"virus":[6,103,277],"was":[7,19],"generated":[8,263],"by":[9,264],"reassortment":[10],"of":[11,15,45,54,64,67,78,92,188,203,248,272,288,299,315],"swine":[12,68,141,153,179,190,250,316],"viruses":[14,44,70,87,124,137,156,166,251,262],"different":[16,65],"lineages.":[17],"This":[18],"the":[20,31,36,51,62,93,113,128,139,169,219,225,233,249,266,300,311],"first":[21,32],"to":[24,33,49,60,245],"emerge":[25],"in":[26,88,112,127,197,210,218,258],"over":[27],"4":[28],"decades":[29],"and":[30,71,83,98,121,131,161,208,213,235,270,274],"occur":[34],"after":[35],"realization":[37],"that":[38,77,102,279,295],"pandemics":[40],"arise":[41],"from":[42,74,138,194,227],"animals.":[46],"In":[47,134,243],"order":[48],"understand":[50],"biological":[52,307],"determinants":[53,287],"emergence,":[56],"it":[57],"is":[58],"relevant":[59],"compare":[61],"tropism":[63,231,257],"lineages":[66],"reassortants":[72],"derived":[73],"them":[75],"with":[76,183,224],"seasonal":[84,122,254,275],"ex":[89,296],"vivo":[90,297],"cultures":[91,298],"human":[94,114,148,211,259,301,312],"nasopharynx,":[95],"bronchus,":[96],"alveoli,":[97],"conjunctiva.":[99,260],"We":[100],"hypothesized":[101],"which":[104],"can":[105],"transmit":[106],"efficiently":[107,126],"between":[108],"humans":[109],"replicated":[110,125,209],"well":[111],"upper":[115],"airways.":[116],"As":[117],"previously":[118],"reported,":[119],"H1N1pdm":[120,195,228,273],"nasopharyngeal,":[129],"bronchial,":[130],"alveolar":[132,159,241],"epithelium.":[133,242],"contrast,":[135],"representative":[136],"classical":[140],"(CS)":[142],"(H1N1)":[143,155],"lineage":[144],"could":[145],"not":[146,217],"infect":[147],"respiratory":[149,302],"epithelium;":[150],"Eurasian":[151],"avian-like":[152],"(EA)":[154],"only":[157,167,196],"infected":[158,168,207],"epithelium":[160,171],"North":[162],"American":[163],"triple-reassortant":[164,178],"(TRIG)":[165],"bronchial":[170,214],"albeit":[172],"inefficiently.":[173],"Interestingly,":[174],"a":[175,184,199,305],"naturally":[176],"occurring":[177],"virus,":[180],"A/SW/HK/915/04":[181],"(H1N2),":[182],"matrix":[185],"gene":[186,202,282],"segment":[187],"EA":[189,204],"derivation":[191],"(i.e.,":[192],"differing":[193],"lacking":[198],"neuraminidase":[200],"[NA]":[201],"derivation)":[205],"readily":[206],"nasopharyngeal":[212],"epithelia":[215],"but":[216],"lung.":[220],"A":[221],"recombinant":[222],"sw915":[223],"NA":[226],"retained":[229],"its":[230],"for":[232,240,309],"bronchus":[234],"acquired":[236],"additional":[237],"replication":[238],"competence":[239],"contrast":[244],"H1N1pdm,":[246],"none":[247],"tested":[252],"nor":[253],"had":[256],"Recombinant":[261],"swapping":[265],"surface":[267],"proteins":[268],"(hemagglutinin":[269],"NA)":[271],"demonstrated":[278],"these":[280,292],"two":[281],"segments":[283],"together":[284],"are":[285],"key":[286],"conjunctival":[289],"tropism.":[290],"Overall,":[291],"findings":[293],"suggest":[294],"tract":[303],"provide":[304],"useful":[306],"model":[308],"assessing":[310],"health":[313],"risk":[314],"viruses.":[318]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
