{"id":"https://openalex.org/W2118286240","doi":null,"title":"The effects of subclinical hypothyroidism on serum lipid level and TLR4 expression of monocyte in peripheral blood of rats.","display_name":"The effects of subclinical hypothyroidism on serum lipid level and TLR4 expression of monocyte in peripheral blood of rats.","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2118286240","mag":"2118286240","pmid":"https://pubmed.ncbi.nlm.nih.gov/24625920"},"language":"en","primary_location":{"id":"pmid:24625920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24625920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro endocrinology letters","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Shuan-suo Yang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuan-suo Yang","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101842022","display_name":"Lei Tang","orcid":"https://orcid.org/0009-0002-2679-0701","observed_orcids":["https://orcid.org/0009-0002-2679-0701","https://orcid.org/0000-0002-5662-095X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lei Tang","raw_affiliation_strings":["Shanghai Institute of Health Sciences, Shanghai 201318, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Institute of Health Sciences, Shanghai 201318, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059015013","display_name":"Ruo-gu Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802608112","display_name":"Shanghai Chest Hospital","ror":"https://ror.org/03fjc3817","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802608112"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruo-gu Li","raw_affiliation_strings":["Department of Cardiology, Shanghai Chest Hospital, Shanghai 200030, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Shanghai Chest Hospital, Shanghai 200030, China","institution_ids":["https://openalex.org/I2802608112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024100735","display_name":"Guanghao Ge","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guang-hao Ge","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103069627","display_name":"Xinkai Qu","orcid":"https://orcid.org/0000-0001-9878-500X","observed_orcids":["https://orcid.org/0000-0001-9878-500X"]},"institutions":[{"id":"https://openalex.org/I2802608112","display_name":"Shanghai Chest Hospital","ror":"https://ror.org/03fjc3817","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802608112"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin-kai Qu","raw_affiliation_strings":["Department of Cardiology, Shanghai Chest Hospital, Shanghai 200030, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Shanghai Chest Hospital, Shanghai 200030, China","institution_ids":["https://openalex.org/I2802608112"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jiang-wei Ma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiang-wei Ma","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113675671","display_name":"Zengyong Qiao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zeng-yong Qiao","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115959251","display_name":"Li Zhang","orcid":"https://orcid.org/0000-0003-1620-1512","observed_orcids":["https://orcid.org/0000-0003-1620-1512"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li Zhang","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070850478","display_name":"Huajin Liu","orcid":"https://orcid.org/0000-0002-9319-1162","observed_orcids":["https://orcid.org/0000-0002-9319-1162"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hua-jin Liu","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039107335","display_name":"Yuemei Hou","orcid":"https://orcid.org/0000-0002-1616-6537","observed_orcids":["https://orcid.org/0000-0002-1616-6537"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yue-mei Hou","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hua Cao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hua Cao","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100705396","display_name":"Zhimin Hao","orcid":"https://orcid.org/0000-0001-8582-5690","observed_orcids":["https://orcid.org/0000-0001-8582-5690"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhi-min Hao","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wen-bo Cheng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wen-bo Cheng","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046712043","display_name":"Hongwei Wang","orcid":"https://orcid.org/0000-0002-1258-5371","observed_orcids":["https://orcid.org/0000-0002-1258-5371"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hong-wei Wang","raw_affiliation_strings":["Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Central Hospital, Fengxian District, Shanghai 201400, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3079,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.80493382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"35","issue":"1","first_page":"80","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subclinical-hypothyroidism","display_name":"subclinical hypothyroidism","score":1.0},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.621999979019165},{"id":"https://openalex.org/keywords/tlr4","display_name":"TLR4","score":0.9089999794960022},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.7789999842643738},{"id":"https://openalex.org/keywords/peripheral-blood-mononuclear-cells","display_name":"peripheral blood mononuclear cells","score":0.9800000190734863},{"id":"https://openalex.org/keywords/nf-kappab-p65","display_name":"NF-\u03baB p65","score":0.8500000238418579},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8629999756813049},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9430000185966492},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.7879999876022339},{"id":"https://openalex.org/keywords/thyroxine","display_name":"thyroxine","score":0.5460000038146973},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.7519999742507935},{"id":"https://openalex.org/keywords/thyroidectomy","display_name":"thyroidectomy","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.831659197807312},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.813855767250061},{"id":"https://openalex.org/C2776070231","wikidata":"https://www.wikidata.org/wiki/Q14914098","display_name":"TLR4","level":3,"score":0.6412975788116455},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.6378434300422668},{"id":"https://openalex.org/C109115496","wikidata":"https://www.wikidata.org/wiki/Q2539644","display_name":"Thyroid hormone receptor","level":3,"score":0.5408445596694946},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.506548285484314},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.48658883571624756},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.48065245151519775},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48008233308792114},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.43956902623176575},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.4323498606681824},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.42338281869888306},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.41460278630256653},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3048824071884155},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.21019721031188965},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013974","descriptor_name":"Thyroxine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013974","descriptor_name":"Thyroxine","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013974","descriptor_name":"Thyroxine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013974","descriptor_name":"Thyroxine","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051197","descriptor_name":"Toll-Like Receptor 4","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D051197","descriptor_name":"Toll-Like Receptor 4","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:24625920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24625920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro endocrinology letters","raw_type":"Journal Article"},{"id":"mag:2118286240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24625920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W70016631","https://openalex.org/W1483162601","https://openalex.org/W1534378060","https://openalex.org/W1545226589","https://openalex.org/W1597094273","https://openalex.org/W1985511669","https://openalex.org/W1990139351","https://openalex.org/W2006348886","https://openalex.org/W2008325595","https://openalex.org/W2087975771","https://openalex.org/W2092564891","https://openalex.org/W2140936682","https://openalex.org/W2142296338","https://openalex.org/W2144225124","https://openalex.org/W2158811811","https://openalex.org/W2165626477","https://openalex.org/W2167448955","https://openalex.org/W2168069158","https://openalex.org/W2324841714"],"related_works":["https://openalex.org/W6911533900","https://openalex.org/W4415423375","https://openalex.org/W2025361248","https://openalex.org/W2394339390","https://openalex.org/W3148222271","https://openalex.org/W6930074053","https://openalex.org/W3216121244","https://openalex.org/W1968502070","https://openalex.org/W4298444605","https://openalex.org/W2489056317"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"observe":[2],"effect":[3],"of":[4,14,63,84,122,185,208],"subclinical":[5],"hypothyroidism":[6],"(SCH)":[7],"on":[8],"serum":[9,85,216,228],"lipid":[10,110,115,120],"level":[11],"and":[12,44,96,113,140,149,169,176,193,198,210],"expression":[13,133,195,214],"toll-like":[15],"receptor":[16],"4":[17],"(TLR4)":[18],"in":[19,103,147,174,215,220],"rats'":[20],"peripheral":[21,76],"blood":[22,77,129],"mononuclear":[23],"cells":[24],"(PBMC).":[25],"METHODS:":[26],"Fifty":[27],"Wistar":[28],"female":[29],"rats":[30,71],"were":[31,72,106,126,144,164,171,181,217],"divided":[32,107],"into":[33,108],"three":[34],"groups:":[35],"normal":[36,109],"control":[37],"(NC":[38],"group;":[39],"n=10),":[40],"sham":[41,177],"group":[42,47,105],"(n=10),":[43],"L-T-4":[45,104],"(L-thyroxine)":[46],"(n=30,":[48],"with":[49,52],"thyroidectomy,":[50],"fed":[51],"rich-calcium":[53],"water":[54],"after":[55],"operation.":[56],"5":[57],"weeks":[58,68],"later,":[59,69],"abdominal":[60],"subcutaneous":[61],"injection":[62],"L-T-4:":[64],"0.95":[65],"\u03bcg/100g/d).":[66],"8":[67],"the":[70,75,82],"killed":[73],"then":[74],"was":[78,224],"collected":[79],"to":[80,119,130,227],"determine":[81,131],"levels":[83],"thyroid-stimulating":[86],"hormone":[87,91],"(TSH),":[88],"total":[89,93],"thyroid":[90],"(TT4),":[92],"cholesterol":[94],"(TC)":[95],"low":[97],"density":[98],"lipoprotein":[99],"cholesterin":[100],"(LDL-C).":[101],"Rats":[102],"(NL)":[111],"group)":[112,117],"high":[114],"(HL)":[116],"according":[118],"value":[121],"NC":[123,148,175],"group.":[124],"Monocytes":[125],"separated":[127],"from":[128],"TLR4":[132,160,187,204],"by":[134],"flow":[135],"cytometry.":[136],"RESULTS:":[137],"In":[138],"NL":[139,197],"HL":[141,199],"groups":[142,151,178,200],"TSH":[143],"higher":[145,172],"than":[146,173],"Sham":[150],"(p<0.05).":[152,166],"TT4":[153],"have":[154],"no":[155,182],"significant":[156,183],"differences":[157,184],"(p>0.05).":[158,201],"TLR4,":[159,186,203],"mRNA,":[161,188,205],"NF-\u03baB":[162,189,206],"(p65)":[163,207],"increased":[165,219],"TNF-\u03b1,":[167,191,211],"IL-6":[168,192],"IL-1\u03b2":[170,194,213],"(p<0.01).":[179],"There":[180],"(p65),":[190],"between":[196],"CONCLUSION:":[202],"PBMC":[209],"IL-6,":[212],"all":[218],"SCH":[221],"rats,":[222],"which":[223],"not":[225],"related":[226],"dyslipidemia.":[229]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}