{"id":"https://openalex.org/W2117752152","doi":"https://doi.org/10.1186/1476-511x-6-21","title":"Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?","display_name":"Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W2117752152","doi":"https://doi.org/10.1186/1476-511x-6-21","mag":"2117752152","pmid":"https://pubmed.ncbi.nlm.nih.gov/17877810","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2071911"},"language":"en","primary_location":{"id":"doi:10.1186/1476-511x-6-21","doi":"https://doi.org/10.1186/1476-511x-6-21","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1476-511x-6-21","pdf_url":null,"source":{"id":"https://openalex.org/S188748365","display_name":"Lipids in Health and Disease","issn_l":"1476-511X","issn":["1476-511X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids in Health and Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/1476-511x-6-21","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103500204","display_name":"Brian M. Ross","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72541430","display_name":"Lakehead University","ror":"https://ror.org/023p7mg82","country_code":"CA","type":"education","lineage":["https://openalex.org/I72541430"]},{"id":"https://openalex.org/I7899908","display_name":"NOSM University","ror":"https://ror.org/05yb43k62","country_code":"CA","type":"education","lineage":["https://openalex.org/I7899908"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Brian M Ross","raw_affiliation_strings":["Northern Ontario School of Medicine, Public Health Program, and Department of Chemistry, Lakehead University, Thunder Bay, Ontario, Canada. brian.ross@normed.ca","Northern Ontario School of Medicine, Public Health Program, and Departments of Chemistry and Biology, Lakehead University, Thunder Bay, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northern Ontario School of Medicine, Public Health Program, and Department of Chemistry, Lakehead University, Thunder Bay, Ontario, Canada. brian.ross@normed.ca","institution_ids":["https://openalex.org/I72541430","https://openalex.org/I7899908"]},{"raw_affiliation_string":"Northern Ontario School of Medicine, Public Health Program, and Departments of Chemistry and Biology, Lakehead University, Thunder Bay, Canada","institution_ids":["https://openalex.org/I72541430","https://openalex.org/I7899908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042263108","display_name":"Jennifer Seguin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer Seguin","raw_affiliation_strings":["Department of Psychology, Thunder Bay, Ontario, Canada","Department of Psychology, Thunder Bay, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Thunder Bay, Ontario, Canada","institution_ids":[]},{"raw_affiliation_string":"Department of Psychology, Thunder Bay, Canada","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040350210","display_name":"Lee E. Sieswerda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287584","display_name":"Thunder Bay District Health Unit","ror":"https://ror.org/05krq7f34","country_code":"CA","type":"government","lineage":["https://openalex.org/I4405287584"]},{"id":"https://openalex.org/I72541430","display_name":"Lakehead University","ror":"https://ror.org/023p7mg82","country_code":"CA","type":"education","lineage":["https://openalex.org/I72541430"]},{"id":"https://openalex.org/I7899908","display_name":"NOSM University","ror":"https://ror.org/05yb43k62","country_code":"CA","type":"education","lineage":["https://openalex.org/I7899908"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Lee E Sieswerda","raw_affiliation_strings":["Thunder Bay District Health Unit and Northern Ontario School of Medicine, Lakehead University, Thunder Bay, Ontario, Canada","Thunder Bay District Health Unit and Northern Ontario School of Medicine, Lakehead University, Thunder Bay, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thunder Bay District Health Unit and Northern Ontario School of Medicine, Lakehead University, Thunder Bay, Ontario, Canada","institution_ids":["https://openalex.org/I4405287584","https://openalex.org/I72541430","https://openalex.org/I7899908"]},{"raw_affiliation_string":"Thunder Bay District Health Unit and Northern Ontario School of Medicine, Lakehead University, Thunder Bay, Canada","institution_ids":["https://openalex.org/I4405287584","https://openalex.org/I72541430","https://openalex.org/I7899908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103500204"],"corresponding_institution_ids":["https://openalex.org/I72541430","https://openalex.org/I7899908"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":16.0339,"has_fulltext":false,"cited_by_count":284,"citation_normalized_percentile":{"value":0.99568507,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"6","issue":"1","first_page":"21","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/omega-3-polyunsaturated-fatty-acids","display_name":"omega-3 polyunsaturated fatty acids","score":0.953000009059906},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.6660000085830688},{"id":"https://openalex.org/keywords/mental-disorders","display_name":"mental illness","score":0.8209999799728394},{"id":"https://openalex.org/keywords/mood-disorders","display_name":"mood disorders","score":0.984000027179718},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.9369999766349792},{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":1.0},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.6959999799728394},{"id":"https://openalex.org/keywords/borderline-personality-disorder","display_name":"borderline personality disorder","score":0.9800000190734863},{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.8330000042915344},{"id":"https://openalex.org/keywords/eicosapentaenoic-acid","display_name":"eicosapentaenoic acid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/docosahexaenoic-acid","display_name":"docosahexaenoic acid","score":1.0},{"id":"https://openalex.org/keywords/meta-regression","display_name":"meta-regression","score":0.5569999814033508}],"concepts":[{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.5956873297691345},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5742089152336121},{"id":"https://openalex.org/C2776091944","wikidata":"https://www.wikidata.org/wiki/Q409990","display_name":"Eicosapentaenoic acid","level":4,"score":0.5669232606887817},{"id":"https://openalex.org/C2777134132","wikidata":"https://www.wikidata.org/wiki/Q188638","display_name":"Mood disorders","level":3,"score":0.541722297668457},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.5211865305900574},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.49016818404197693},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.4897921085357666},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.48571404814720154},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.485087513923645},{"id":"https://openalex.org/C3017514745","wikidata":"https://www.wikidata.org/wiki/Q191756","display_name":"Omega 3 fatty acid","level":5,"score":0.43902498483657837},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4135338068008423},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3614285886287689},{"id":"https://openalex.org/C2777171753","wikidata":"https://www.wikidata.org/wiki/Q423345","display_name":"Docosahexaenoic acid","level":4,"score":0.3443136215209961},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.2337707281112671},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10943537950515747},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001523","descriptor_name":"Mental Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010551","descriptor_name":"Personality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1476-511x-6-21","doi":"https://doi.org/10.1186/1476-511x-6-21","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1476-511x-6-21","pdf_url":null,"source":{"id":"https://openalex.org/S188748365","display_name":"Lipids in Health and Disease","issn_l":"1476-511X","issn":["1476-511X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids in Health and Disease","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2071911","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2071911","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids Health Dis","raw_type":"Text"},{"id":"pmid:17877810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17877810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids in health and disease","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:260f9a41019f4cf195d867f87a9676c4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/260f9a41019f4cf195d867f87a9676c4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lipids in Health and Disease, Vol 6, Iss 1, p 21 (2007)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1476-511x-6-21","doi":"https://doi.org/10.1186/1476-511x-6-21","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1476-511x-6-21","pdf_url":null,"source":{"id":"https://openalex.org/S188748365","display_name":"Lipids in Health and Disease","issn_l":"1476-511X","issn":["1476-511X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids in Health and Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320313495","display_name":"Lakehead University","ror":"https://ror.org/023p7mg82"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":132,"referenced_works":["https://openalex.org/W51627854","https://openalex.org/W560409725","https://openalex.org/W607947957","https://openalex.org/W1480729244","https://openalex.org/W1483112721","https://openalex.org/W1556485502","https://openalex.org/W1561051627","https://openalex.org/W1569413811","https://openalex.org/W1581169419","https://openalex.org/W1859695485","https://openalex.org/W1895462365","https://openalex.org/W1895781480","https://openalex.org/W1923482916","https://openalex.org/W1935497906","https://openalex.org/W1965892473","https://openalex.org/W1966969969","https://openalex.org/W1972584971","https://openalex.org/W1973929440","https://openalex.org/W1975464025","https://openalex.org/W1976700610","https://openalex.org/W1979122474","https://openalex.org/W1980329209","https://openalex.org/W1981736255","https://openalex.org/W1982415357","https://openalex.org/W1984757473","https://openalex.org/W1985514982","https://openalex.org/W1986084664","https://openalex.org/W1986215651","https://openalex.org/W1986482524","https://openalex.org/W1987061769","https://openalex.org/W1989812164","https://openalex.org/W1990660916","https://openalex.org/W1991671460","https://openalex.org/W2001053592","https://openalex.org/W2001166189","https://openalex.org/W2003708984","https://openalex.org/W2004481406","https://openalex.org/W2012450128","https://openalex.org/W2015011983","https://openalex.org/W2016315816","https://openalex.org/W2016655876","https://openalex.org/W2018883062","https://openalex.org/W2020561358","https://openalex.org/W2022982246","https://openalex.org/W2023311435","https://openalex.org/W2027780481","https://openalex.org/W2029191095","https://openalex.org/W2029212126","https://openalex.org/W2029533897","https://openalex.org/W2029658707","https://openalex.org/W2034194523","https://openalex.org/W2034941199","https://openalex.org/W2037071915","https://openalex.org/W2038693293","https://openalex.org/W2039066744","https://openalex.org/W2039178589","https://openalex.org/W2052445727","https://openalex.org/W2053612684","https://openalex.org/W2054486548","https://openalex.org/W2061881919","https://openalex.org/W2064375795","https://openalex.org/W2065760254","https://openalex.org/W2067495470","https://openalex.org/W2069039029","https://openalex.org/W2069224827","https://openalex.org/W2069364515","https://openalex.org/W2071187424","https://openalex.org/W2071373294","https://openalex.org/W2075972771","https://openalex.org/W2076856384","https://openalex.org/W2077421021","https://openalex.org/W2078335108","https://openalex.org/W2078601079","https://openalex.org/W2081040380","https://openalex.org/W2082649626","https://openalex.org/W2087535390","https://openalex.org/W2088496064","https://openalex.org/W2089036448","https://openalex.org/W2091963515","https://openalex.org/W2100726346","https://openalex.org/W2100851898","https://openalex.org/W2101513524","https://openalex.org/W2102023134","https://openalex.org/W2106069988","https://openalex.org/W2109279406","https://openalex.org/W2110301859","https://openalex.org/W2111413699","https://openalex.org/W2111614110","https://openalex.org/W2114613490","https://openalex.org/W2114848027","https://openalex.org/W2116968268","https://openalex.org/W2122634210","https://openalex.org/W2123822033","https://openalex.org/W2127124395","https://openalex.org/W2130279922","https://openalex.org/W2130380236","https://openalex.org/W2131417790","https://openalex.org/W2131823335","https://openalex.org/W2132025144","https://openalex.org/W2138062382","https://openalex.org/W2138676964","https://openalex.org/W2140606211","https://openalex.org/W2145336940","https://openalex.org/W2145336951","https://openalex.org/W2145465352","https://openalex.org/W2145908741","https://openalex.org/W2148954819","https://openalex.org/W2150376579","https://openalex.org/W2153299553","https://openalex.org/W2155060392","https://openalex.org/W2157139186","https://openalex.org/W2159011576","https://openalex.org/W2162066663","https://openalex.org/W2163651074","https://openalex.org/W2164339448","https://openalex.org/W2167659819","https://openalex.org/W2168486153","https://openalex.org/W2171401470","https://openalex.org/W2171688276","https://openalex.org/W2298420059","https://openalex.org/W2410979608","https://openalex.org/W2547992983","https://openalex.org/W2972479659","https://openalex.org/W2998370832","https://openalex.org/W3086537066","https://openalex.org/W3090293687","https://openalex.org/W3151816160","https://openalex.org/W4211032287","https://openalex.org/W4231032588","https://openalex.org/W4238583900","https://openalex.org/W4241321934","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4412885032","https://openalex.org/W2321269778","https://openalex.org/W2492567170","https://openalex.org/W2141782374","https://openalex.org/W2150955013","https://openalex.org/W2982007797","https://openalex.org/W1979122474","https://openalex.org/W3104421875","https://openalex.org/W1865691147","https://openalex.org/W3012055278"],"abstract_inverted_index":{"BACKGROUND:":[0],"A":[1,151,209],"growing":[2],"number":[3,86],"of":[4,27,41,47,87,125,134,154,160,183,199,211,230,265,277,297],"observational":[5],"and":[6,102,117,139,190,219,339],"epidemiological":[7],"studies":[8],"have":[9,52],"suggested":[10,157],"that":[11,158,177,224,236],"mental":[12,321],"illness,":[13,322],"in":[14,44,77,167,206,245,280,319],"particular":[15],"mood":[16,207,246,281,340],"disorders,":[17,141],"is":[18,188,202,268,289,305,326],"associated":[19],"with":[20,104,215,238,249,334],"reduced":[21],"dietary":[22],"intake":[23],"and/or":[24],"cellular":[25],"abundance":[26],"omega-3":[28,42,70,161,178,200,225,266,278,311],"polyunsaturated":[29],"fatty":[30],"acids":[31],"(PUFA).":[32],"This":[33],"has":[34],"prompted":[35],"researchers":[36],"to":[37,64,67,74,203,284,300,309,329,336],"test":[38],"the":[39,55,109,132,186,274,293,323],"efficacy":[40,276,296],"PUFA":[43,71,95,162,179,201,226,267,279,312],"a":[45,84,126,168,257,290,315],"range":[46],"different":[48],"psychiatric":[49],"disorders.":[50,79,208,341],"We":[51],"critically":[53],"reviewed":[54],"double":[56],"blind":[57],"placebo":[58],"controlled":[59],"clinical":[60],"trials":[61,82,143,156,212],"published":[62],"prior":[63],"April":[65],"2007":[66],"determine":[68],"whether":[69],"are":[72,286],"likely":[73],"be":[75,165,204,242],"efficacious":[76],"these":[78,155],"RESULTS:":[80],"Most":[81],"involved":[83],"small":[85,147],"participants":[88],"but":[89],"were":[90,96],"largely":[91],"well":[92,97],"designed.":[93],"Omega-3":[94],"tolerated":[98],"by":[99],"both":[100],"children":[101],"adults":[103],"mild":[105],"gastrointestinal":[106],"effects":[107,198],"being":[108,260],"only":[110],"consistently":[111],"reported":[112],"adverse":[113],"event.":[114],"For":[115],"schizophrenia":[116,285],"borderline":[118],"personality":[119],"disorder":[120,138,218,221],"we":[121],"found":[122,205],"little":[123],"evidence":[124,175,195,223,325],"robust":[127],"clinically":[128],"relevant":[129],"effect.":[130],"In":[131],"case":[133],"attention":[135],"deficit":[136],"hyperactivity":[137],"related":[140],"most":[142,146,193,269],"showed":[144],"at":[145,172],"benefits":[148,159],"over":[149],"placebo.":[150],"limited":[152],"meta-analysis":[153,210],"supplementation":[163,227,237],"may":[164,180,241],"greater":[166,295],"classroom":[169],"setting":[170],"than":[171,248],"home.":[173],"Some":[174],"indicates":[176],"reduce":[181],"symptoms":[182,229],"anxiety":[184,338],"although":[185,252],"data":[187],"preliminary":[189],"inconclusive.":[191],"The":[192,271],"convincing":[194],"for":[196,292],"beneficial":[197,244],"involving":[213],"patients":[214],"major":[216],"depressive":[217],"bipolar":[220],"provided":[222],"reduces":[228],"depression.":[231],"Furthermore,":[232],"meta-regression":[233],"analysis":[234],"suggests":[235],"eicosapentaenoic":[239],"acid":[240],"more":[243],"disorders":[247,282],"docosahexaenoic":[250],"acid,":[251],"several":[253],"confounding":[254],"factors":[255],"prevented":[256],"definitive":[258],"conclusion":[259],"made":[261],"regarding":[262],"which":[263],"species":[264],"beneficial.":[270],"mechanisms":[272],"underlying":[273],"apparent":[275],"compared":[283,299],"discussed":[287],"as":[288,313],"rational":[291],"possibly":[294],"EPA":[298],"DHA.":[301],"CONCLUSION:":[302],"While":[303],"it":[304],"not":[306],"currently":[307],"possible":[308],"recommend":[310],"either":[314],"mono-":[316],"or":[317],"adjunctive-therapy":[318],"any":[320],"available":[324],"strong":[327],"enough":[328],"justify":[330],"continued":[331],"study,":[332],"especially":[333],"regard":[335],"attentional,":[337]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":16},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":22},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":23}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
