{"id":"https://openalex.org/W2117182147","doi":null,"title":"Comparison of the effects of ethinyl estradiol and genistein on serum lipids and lipoproteins of hypercholestrolemic male rats","display_name":"Comparison of the effects of ethinyl estradiol and genistein on serum lipids and lipoproteins of hypercholestrolemic male rats","publication_year":2006,"publication_date":"2006-03-10","ids":{"openalex":"https://openalex.org/W2117182147","mag":"2117182147"},"language":"en","primary_location":{"id":"mag:2117182147","doi":null,"is_oa":false,"landing_page_url":"http://phypha.ir/ppj/article-1-254-en.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Physiology and Pharmacology","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081799856","display_name":"Shohreh Iranmanesh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shohreh Iranmanesh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113857662","display_name":"Akbar Vahdati","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akbar Vahdati","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5049736945","display_name":"T Afrouz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Afrouz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"10","issue":"2","first_page":"159","last_page":"164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11318","display_name":"Phytoestrogen effects and research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11318","display_name":"Phytoestrogen effects and research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethinyl-estradiol","display_name":"ethinyl estradiol","score":0.9959999918937683},{"id":"https://openalex.org/keywords/genistein","display_name":"genistein","score":1.0},{"id":"https://openalex.org/keywords/phytoestrogens","display_name":"phytoestrogens","score":0.9610000252723694},{"id":"https://openalex.org/keywords/isoflavones","display_name":"isoflavones","score":0.9089999794960022},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9769999980926514},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.9769999980926514},{"id":"https://openalex.org/keywords/lipoproteins","display_name":"lipoproteins","score":0.9850000143051147},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8059999942779541},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.746999979019165},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8759999871253967},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.8980000019073486},{"id":"https://openalex.org/keywords/vldl-cholesterol","display_name":"VLDL cholesterol","score":0.8629999756813049},{"id":"https://openalex.org/keywords/high-cholesterol-diet","display_name":"high-cholesterol diet","score":0.7620000243186951},{"id":"https://openalex.org/keywords/estrogen-replacement-therapy","display_name":"estrogen replacement therapy","score":0.8650000095367432},{"id":"https://openalex.org/keywords/ldl-catabolism","display_name":"LDL catabolism","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C2778270713","wikidata":"https://www.wikidata.org/wiki/Q414496","display_name":"Phytoestrogens","level":3,"score":0.9509029388427734},{"id":"https://openalex.org/C2778298627","wikidata":"https://www.wikidata.org/wiki/Q415957","display_name":"Genistein","level":2,"score":0.9141254425048828},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7512844204902649},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7316311597824097},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.6517223119735718},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.5896743535995483},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.5286489129066467},{"id":"https://openalex.org/C2779705811","wikidata":"https://www.wikidata.org/wiki/Q412519","display_name":"Isoflavones","level":2,"score":0.49592289328575134},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4237246513366699},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4192201793193817},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3491132855415344}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2117182147","doi":null,"is_oa":false,"landing_page_url":"http://phypha.ir/ppj/article-1-254-en.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Physiology and Pharmacology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1520696669","https://openalex.org/W1805124418","https://openalex.org/W1888974963","https://openalex.org/W1980492886","https://openalex.org/W1987144846","https://openalex.org/W1992827635","https://openalex.org/W1994426012","https://openalex.org/W1998026951","https://openalex.org/W2011941502","https://openalex.org/W2020967365","https://openalex.org/W2046157340","https://openalex.org/W2061369829","https://openalex.org/W2063293597","https://openalex.org/W2112764454","https://openalex.org/W2126688313","https://openalex.org/W2134372734","https://openalex.org/W2136833321","https://openalex.org/W2167283322","https://openalex.org/W2169173496"],"related_works":["https://openalex.org/W4241957878","https://openalex.org/W984361999","https://openalex.org/W2035847814","https://openalex.org/W1592471107","https://openalex.org/W2276245345","https://openalex.org/W1974148190","https://openalex.org/W2059157537","https://openalex.org/W2126688313","https://openalex.org/W2331954515","https://openalex.org/W1998026951"],"abstract_inverted_index":{"Introduction:":[0],"Estrogen":[1],"is":[2,56,289],"one":[3,71,77],"of":[4,22,54,63,70,87,93,96,103,106,149,156,189,193,197,218,221,225,231,237,243,246,250,266,283],"the":[5,20,32,37,51,59,68,111,128,133,136,154,157,164,178,186,190,195,216,223,229,244],"female":[6],"sex":[7],"hormones":[8],"that":[9,44,240,288],"in":[10,98,204,260,268],"addition":[11],"to":[12,91,185,215],"its":[13],"reproductive":[14],"role,":[15],"has":[16],"favorable":[17],"effects":[18,46,69,105],"on":[19,248,275,286],"metabolism":[21],"blood":[23,130,165,276],"lipids":[24,277],"and":[25,27,76,146,160,173,177,207,235,263,278],"lipoproteins":[26],"by":[28],"this":[29,66,88],"way":[30],"decreases":[31],"coronary":[33],"heart":[34],"disease.":[35],"On":[36],"other":[38],"hand,":[39],"phytoestrogens":[40,97],"are":[41,58],"phytochemical":[42],"substances":[43],"have":[45],"like":[47],"estrogens.":[48],"Isoflavones,":[49],"which":[50],"most":[52,60],"important":[53],"them":[55],"genistein,":[57],"common":[61],"form":[62,270],"phytoestrogens.":[64],"In":[65],"research,":[67],"phytoestrogenic":[72],"compounds":[73],"named":[74,80],"genistein":[75,147,267],"estrogenic":[78,107],"compound":[79],"ethinyl":[81,144,226],"estradiol":[82,145,227],"were":[83,113,138,175,180],"compaired.":[84],"The":[85],"purpose":[86],"comparison":[89],"was":[90,241],"study":[92],"replacement":[94],"possibility":[95],"ERT":[99],"period":[100,159,192,220],"for":[101,115,140],"elimination":[102],"side":[104],"compound.":[108],"Methods:":[109],"First":[110],"rats":[112,137,212],"fed":[114],"2":[116,141],"months":[117,142],"with":[118,143],"high":[119,150,198],"cholestrol":[120,151,199,206,234],"diet":[121,200],"(2%":[122],"cholestrol,":[123,169],"0/5%":[124],"cholic":[125],"acid).":[126],"After":[127,153],"first":[129,191],"test":[131],"ensured":[132],"hypercholestrolemic":[134,238],"condition,":[135],"treated":[139],"besides":[148],"diet.":[152],"end":[155],"second":[158,219],"serum":[161,232],"preparation":[162],"from":[163],"samples":[166],"disignated":[167],"total":[168,205,233],"triglyceride,":[170,261],"HDL,":[171],"LDL":[172,208,236,251],"VDL":[174],"measured":[176],"results":[179,188,217],"statistically":[181],"analyzed.":[182],"Results:":[183],"According":[184,214],"obtained":[187],"experiment,":[194,222],"usage":[196,224],"caused":[201],"meaningful":[202,258],"increase":[203,249],"as":[209],"it":[210,254],"made":[211],"hypercholestrolemic.":[213],"reduced":[228],"level":[230],"rats,":[239],"because":[242],"effect":[245,274],"estrogen":[247],"catabolism.":[252],"Whereas,":[253],"did":[255],"not":[256],"produce":[257],"changes":[259],"HDL":[262],"VDL.":[264],"Usage":[265],"isolated":[269],"had":[271],"no":[272],"benefical":[273],"lipoproteins,":[279],"Because":[280],"hypocholestrolemic":[281],"property":[282],"isoflavone":[284],"depends":[285],"matrix":[287],"beside":[290],"it.":[291]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}