{"id":"https://openalex.org/W2116578672","doi":"https://doi.org/10.1093/mutage/12.4.285","title":"Induction of micronuclei by smokeless tobacco on buccal mucosa cells of habitual users","display_name":"Induction of micronuclei by smokeless tobacco on buccal mucosa cells of habitual users","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W2116578672","doi":"https://doi.org/10.1093/mutage/12.4.285","mag":"2116578672","pmid":"https://pubmed.ncbi.nlm.nih.gov/9237775"},"language":"en","primary_location":{"id":"doi:10.1093/mutage/12.4.285","doi":"https://doi.org/10.1093/mutage/12.4.285","is_oa":false,"landing_page_url":"https://doi.org/10.1093/mutage/12.4.285","pdf_url":null,"source":{"id":"https://openalex.org/S101337917","display_name":"Mutagenesis","issn_l":"0267-8357","issn":["0267-8357","1464-3804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutagenesis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110642285","display_name":"Yusuf \u00d6zkul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Yusuf \u00d6zkul","raw_affiliation_strings":["Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University, Kayseri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University, Kayseri, Turkey","institution_ids":["https://openalex.org/I87673952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055158428","display_name":"Hamiyet D\u00f6nmez\u2010Altunta\u015f","orcid":"https://orcid.org/0000-0001-6473-5813","observed_orcids":["https://orcid.org/0000-0001-6473-5813"]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Hamiyet Donmez","raw_affiliation_strings":["Department Medical Biology and Genetics , Faculty of Medicine , Erciyes University , 38039 Kayseri and","Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University38039 Kayseri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medical Biology and Genetics , Faculty of Medicine , Erciyes University , 38039 Kayseri and","institution_ids":["https://openalex.org/I87673952"]},{"raw_affiliation_string":"Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University38039 Kayseri, Turkey","institution_ids":["https://openalex.org/I87673952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078106689","display_name":"Ayd\u0131n Erenmemi\u015fo\u011flu","orcid":"https://orcid.org/0000-0002-9277-1333","observed_orcids":["https://orcid.org/0000-0002-9277-1333"]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Aydin Erenmemisoglu","raw_affiliation_strings":["Department of Pharmacology, Faculty of Medicine, Erciyes University 38039 Kayseri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medicine, Erciyes University 38039 Kayseri, Turkey","institution_ids":["https://openalex.org/I87673952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109078336","display_name":"Halil Demirta\u015f","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Halil Demirtas","raw_affiliation_strings":["Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University 38039 Kayseri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University 38039 Kayseri, Turkey","institution_ids":["https://openalex.org/I87673952"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056022030","display_name":"Nalan \u0130mamo\u011flu","orcid":"https://orcid.org/0000-0003-2401-8320","observed_orcids":["https://orcid.org/0000-0003-2401-8320"]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nalan Imamoglu","raw_affiliation_strings":["Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University 38039 Kayseri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medical Biology and Genetics, Faculty of Medicine, Erciyes University 38039 Kayseri, Turkey","institution_ids":["https://openalex.org/I87673952"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I87673952"],"apc_list":{"value":3162,"currency":"GBP","value_usd":4170},"apc_paid":null,"fwci":0.1414,"has_fulltext":true,"cited_by_count":94,"citation_normalized_percentile":{"value":0.43784187,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"4","first_page":"285","last_page":"287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/smokeless-tobacco","display_name":"smokeless tobacco","score":0.9779999852180481},{"id":"https://openalex.org/keywords/micronuclei","display_name":"micronuclei","score":0.8700000047683716},{"id":"https://openalex.org/keywords/buccal-mucosa","display_name":"buccal mucosa","score":0.8790000081062317},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":0.968999981880188},{"id":"https://openalex.org/keywords/smokers","display_name":"smokers","score":0.6499999761581421},{"id":"https://openalex.org/keywords/oral-carcinogens","display_name":"oral carcinogens","score":0.48899999260902405},{"id":"https://openalex.org/keywords/tobacco-use","display_name":"tobacco use","score":0.43799999356269836}],"concepts":[{"id":"https://openalex.org/C138040679","wikidata":"https://www.wikidata.org/wiki/Q3512694","display_name":"Smokeless tobacco","level":4,"score":0.9677410125732422},{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.8751146793365479},{"id":"https://openalex.org/C2991923528","wikidata":"https://www.wikidata.org/wiki/Q1776131","display_name":"Buccal mucosa","level":3,"score":0.8433536291122437},{"id":"https://openalex.org/C167871757","wikidata":"https://www.wikidata.org/wiki/Q4982391","display_name":"Buccal swab","level":2,"score":0.7101136445999146},{"id":"https://openalex.org/C195735259","wikidata":"https://www.wikidata.org/wiki/Q16963239","display_name":"Buccal administration","level":2,"score":0.6366399526596069},{"id":"https://openalex.org/C36681516","wikidata":"https://www.wikidata.org/wiki/Q1700733","display_name":"Micronucleus","level":4,"score":0.547429084777832},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5286988019943237},{"id":"https://openalex.org/C95044740","wikidata":"https://www.wikidata.org/wiki/Q212894","display_name":"Snuff","level":2,"score":0.45408231019973755},{"id":"https://openalex.org/C2779409057","wikidata":"https://www.wikidata.org/wiki/Q1776131","display_name":"Oral mucosa","level":2,"score":0.4127996563911438},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.38135862350463867},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.34435755014419556},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.3372201919555664},{"id":"https://openalex.org/C3019190695","wikidata":"https://www.wikidata.org/wiki/Q7212330","display_name":"Tobacco use","level":3,"score":0.33302539587020874},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.33302009105682373},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26444128155708313},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24926337599754333},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.24100342392921448},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.16964176297187805},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16196084022521973},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.13967850804328918},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.10247939825057983}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010947","descriptor_name":"Plants, Toxic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014030","descriptor_name":"Tobacco, Smokeless","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D015162","descriptor_name":"Micronucleus Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048629","descriptor_name":"Micronuclei, Chromosome-Defective","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/mutage/12.4.285","doi":"https://doi.org/10.1093/mutage/12.4.285","is_oa":false,"landing_page_url":"https://doi.org/10.1093/mutage/12.4.285","pdf_url":null,"source":{"id":"https://openalex.org/S101337917","display_name":"Mutagenesis","issn_l":"0267-8357","issn":["0267-8357","1464-3804"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutagenesis","raw_type":"journal-article"},{"id":"pmid:9237775","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9237775","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutagenesis","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.424.7466","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.424.7466","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://mutage.oxfordjournals.org/content/12/4/285.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1963799462","https://openalex.org/W1964829756","https://openalex.org/W1991940284","https://openalex.org/W2006906049","https://openalex.org/W2033708932","https://openalex.org/W2046931578","https://openalex.org/W2080462666","https://openalex.org/W2163705038"],"related_works":["https://openalex.org/W7099532166","https://openalex.org/W2143141976","https://openalex.org/W1973496533","https://openalex.org/W2035279564","https://openalex.org/W7046072749","https://openalex.org/W4292712534","https://openalex.org/W6885042722","https://openalex.org/W2894836899","https://openalex.org/W2027297057","https://openalex.org/W2922102997"],"abstract_inverted_index":{"Maras":[0,33],"Powder":[1,34],"is":[2],"a":[3],"kind":[4],"of":[5,12,18,31,52,75,98,110],"smokeless":[6,60,111],"tobacco":[7,44,61,112],"widely":[8],"used":[9],"in":[10,14,27,59,66,82,88,101,116],"lieu":[11],"cigarettes":[13],"the":[15,95,107],"South-Eastern":[16],"region":[17],"Turkey.":[19],"In":[20,105],"this":[21],"study,":[22],"we":[23,37],"have":[24],"evaluated":[25],"micronuclei":[26],"buccal":[28],"mucosa":[29],"cells":[30,55,77,100],"habitual":[32],"users.":[35],"Therefore,":[36],"divided":[38],"our":[39],"subjects":[40],"into":[41],"three":[42],"groups--smokeless":[43],"users,":[45],"smokers":[46,64],"and":[47,63,84],"non-smokers/non-users.":[48],"The":[49,72],"mean":[50,73,96],"percentage":[51,74,97],"micronucleated":[53],"(MN)":[54],"was":[56,78,91],"significantly":[57],"higher":[58],"users":[62,83],"than":[65],"non-smokers/non-users":[67],"(P":[68],"<":[69],"0.01)":[70],"[corrected].":[71],"MN":[76,99],"1.86":[79],"+/-":[80,86],"0.26":[81],"1.99":[85],"0.30":[87],"smokers.":[89],"There":[90],"no":[92],"difference":[93],"between":[94],"these":[102],"two":[103],"groups.":[104],"conclusion,":[106],"genotoxic":[108],"effect":[109],"should":[113],"be":[114],"considered":[115],"addition":[117],"to":[118],"other":[119],"known":[120],"hazards.":[121]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}