{"id":"https://openalex.org/W2116168356","doi":"https://doi.org/10.1146/annurev-physiol-021113-170406","title":"Trafficking of Epidermal Growth Factor Receptor Ligands in Polarized Epithelial Cells","display_name":"Trafficking of Epidermal Growth Factor Receptor Ligands in Polarized Epithelial Cells","publication_year":2013,"publication_date":"2013-11-11","ids":{"openalex":"https://openalex.org/W2116168356","doi":"https://doi.org/10.1146/annurev-physiol-021113-170406","mag":"2116168356","pmid":"https://pubmed.ncbi.nlm.nih.gov/24215440","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4180094"},"language":"en","primary_location":{"id":"doi:10.1146/annurev-physiol-021113-170406","doi":"https://doi.org/10.1146/annurev-physiol-021113-170406","is_oa":false,"landing_page_url":"https://doi.org/10.1146/annurev-physiol-021113-170406","pdf_url":null,"source":{"id":"https://openalex.org/S196366644","display_name":"Annual Review of Physiology","issn_l":"0066-4278","issn":["0066-4278","1545-1585"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Physiology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4180094","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090179644","display_name":"Bhuminder Singh","orcid":"https://orcid.org/0000-0003-1357-2158","observed_orcids":["https://orcid.org/0000-0003-1357-2158"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bhuminder Singh","raw_affiliation_strings":["Departments of Medicine and Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232;,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232;,","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046249010","display_name":"Robert J. Coffey","orcid":"https://orcid.org/0000-0002-2180-3844","observed_orcids":["https://orcid.org/0000-0002-2180-3844"]},"institutions":[{"id":"https://openalex.org/I4210103776","display_name":"Nashville VA Medical Center","ror":"https://ror.org/024xyyq03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210101790","https://openalex.org/I4210103776","https://openalex.org/I4210112672"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert J. Coffey","raw_affiliation_strings":["Department of Veteran Affairs Medical Center, Nashville, Tennessee 37232","Departments of Medicine and Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232;,","email: robert.coffey@vanderbilt.edu , bhuminder.singh@vanderbilt.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veteran Affairs Medical Center, Nashville, Tennessee 37232","institution_ids":["https://openalex.org/I4210103776"]},{"raw_affiliation_string":"Departments of Medicine and Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232;,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"email: robert.coffey@vanderbilt.edu , bhuminder.singh@vanderbilt.edu","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5065,"has_fulltext":false,"cited_by_count":88,"citation_normalized_percentile":{"value":0.44755245,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"76","issue":"1","first_page":"275","last_page":"300"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.6050000190734863,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.6050000190734863,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.3840000033378601,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epidermal-growth-factor-receptor","display_name":"epidermal growth factor receptor","score":0.9890000224113464},{"id":"https://openalex.org/keywords/egfr-ligands","display_name":"EGFR ligands","score":0.9179999828338623},{"id":"https://openalex.org/keywords/polarized-epithelial-cells","display_name":"polarized epithelial cells","score":0.8169999718666077},{"id":"https://openalex.org/keywords/cell-surface-delivery","display_name":"cell surface delivery","score":0.6890000104904175},{"id":"https://openalex.org/keywords/epithelial-homeostasis","display_name":"epithelial homeostasis","score":0.796999990940094},{"id":"https://openalex.org/keywords/renal-tubules","display_name":"renal tubules","score":0.6200000047683716}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7054343819618225},{"id":"https://openalex.org/C39587587","wikidata":"https://www.wikidata.org/wiki/Q5383698","display_name":"Epithelial polarity","level":3,"score":0.6136693954467773},{"id":"https://openalex.org/C2776362946","wikidata":"https://www.wikidata.org/wiki/Q424374","display_name":"Epidermal growth factor","level":3,"score":0.5860229730606079},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.5699054598808289},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5631667971611023},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.4642297625541687},{"id":"https://openalex.org/C3018436504","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Apical membrane","level":3,"score":0.4277743995189667},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.42081689834594727},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3630554676055908},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1537354290485382},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016764","descriptor_name":"Cell Polarity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045726","descriptor_name":"Metalloproteases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1146/annurev-physiol-021113-170406","doi":"https://doi.org/10.1146/annurev-physiol-021113-170406","is_oa":false,"landing_page_url":"https://doi.org/10.1146/annurev-physiol-021113-170406","pdf_url":null,"source":{"id":"https://openalex.org/S196366644","display_name":"Annual Review of Physiology","issn_l":"0066-4278","issn":["0066-4278","1545-1585"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Physiology","raw_type":"journal-article"},{"id":"pmid:24215440","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24215440","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual review of physiology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3287514","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4180094","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4180094","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4180094","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Annu Rev Physiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3287514","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4180094","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4841106333","display_name":"SPORE in GI Cancer","funder_award_id":"P50CA095103","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8487928744","display_name":"Role of EGFR ligand-containing exosomes in colorectal cancer","funder_award_id":"R01CA163563","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8868505193","display_name":"Role of EGFR Ligands in Neoplasia","funder_award_id":"R01CA046413","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":148,"referenced_works":["https://openalex.org/W173973521","https://openalex.org/W179748458","https://openalex.org/W1514034386","https://openalex.org/W1546091009","https://openalex.org/W1588195558","https://openalex.org/W1588812766","https://openalex.org/W1593829141","https://openalex.org/W1594802810","https://openalex.org/W1596261235","https://openalex.org/W1597333775","https://openalex.org/W1665534178","https://openalex.org/W1894632965","https://openalex.org/W1894641937","https://openalex.org/W1924000143","https://openalex.org/W1963690717","https://openalex.org/W1963917958","https://openalex.org/W1964117622","https://openalex.org/W1965309626","https://openalex.org/W1965355187","https://openalex.org/W1965630120","https://openalex.org/W1966041595","https://openalex.org/W1967661601","https://openalex.org/W1970357458","https://openalex.org/W1972036696","https://openalex.org/W1974709736","https://openalex.org/W1976094538","https://openalex.org/W1977993125","https://openalex.org/W1979601948","https://openalex.org/W1980607613","https://openalex.org/W1982681624","https://openalex.org/W1983268824","https://openalex.org/W1988106671","https://openalex.org/W1991888662","https://openalex.org/W1992265794","https://openalex.org/W1994216131","https://openalex.org/W1997114875","https://openalex.org/W1998271033","https://openalex.org/W1998358446","https://openalex.org/W1998897266","https://openalex.org/W2003649795","https://openalex.org/W2006247387","https://openalex.org/W2006257247","https://openalex.org/W2011588324","https://openalex.org/W2012194464","https://openalex.org/W2012322739","https://openalex.org/W2012569825","https://openalex.org/W2016717347","https://openalex.org/W2019772485","https://openalex.org/W2020583316","https://openalex.org/W2022406746","https://openalex.org/W2023172957","https://openalex.org/W2024136850","https://openalex.org/W2026320744","https://openalex.org/W2026792538","https://openalex.org/W2027737365","https://openalex.org/W2028253068","https://openalex.org/W2028811272","https://openalex.org/W2030214706","https://openalex.org/W2030465435","https://openalex.org/W2030662833","https://openalex.org/W2031844898","https://openalex.org/W2033522031","https://openalex.org/W2033559416","https://openalex.org/W2033777508","https://openalex.org/W2034614477","https://openalex.org/W2034696312","https://openalex.org/W2034855589","https://openalex.org/W2034975029","https://openalex.org/W2037369692","https://openalex.org/W2038653804","https://openalex.org/W2049180247","https://openalex.org/W2050046701","https://openalex.org/W2050277370","https://openalex.org/W2054012934","https://openalex.org/W2054615252","https://openalex.org/W2054799018","https://openalex.org/W2055149726","https://openalex.org/W2057151160","https://openalex.org/W2062976091","https://openalex.org/W2063508984","https://openalex.org/W2065314790","https://openalex.org/W2068961038","https://openalex.org/W2069120227","https://openalex.org/W2070903093","https://openalex.org/W2072219853","https://openalex.org/W2073038040","https://openalex.org/W2075663772","https://openalex.org/W2076757423","https://openalex.org/W2079869359","https://openalex.org/W2083197912","https://openalex.org/W2083351068","https://openalex.org/W2084172300","https://openalex.org/W2084817237","https://openalex.org/W2085513070","https://openalex.org/W2094540897","https://openalex.org/W2094703210","https://openalex.org/W2095931710","https://openalex.org/W2096268578","https://openalex.org/W2098202316","https://openalex.org/W2100976544","https://openalex.org/W2103174300","https://openalex.org/W2104278428","https://openalex.org/W2104775386","https://openalex.org/W2106175140","https://openalex.org/W2109319525","https://openalex.org/W2109564400","https://openalex.org/W2109844668","https://openalex.org/W2110803737","https://openalex.org/W2112359053","https://openalex.org/W2113097723","https://openalex.org/W2114882855","https://openalex.org/W2116027412","https://openalex.org/W2117138208","https://openalex.org/W2117993382","https://openalex.org/W2119643278","https://openalex.org/W2124495521","https://openalex.org/W2125269793","https://openalex.org/W2125371725","https://openalex.org/W2126003136","https://openalex.org/W2127806881","https://openalex.org/W2133426307","https://openalex.org/W2135177750","https://openalex.org/W2136306850","https://openalex.org/W2136357968","https://openalex.org/W2137513862","https://openalex.org/W2140998457","https://openalex.org/W2141838148","https://openalex.org/W2143633028","https://openalex.org/W2143935409","https://openalex.org/W2146253307","https://openalex.org/W2149227542","https://openalex.org/W2152770850","https://openalex.org/W2154870995","https://openalex.org/W2157010562","https://openalex.org/W2161817637","https://openalex.org/W2161930851","https://openalex.org/W2162007764","https://openalex.org/W2165832423","https://openalex.org/W2166791970","https://openalex.org/W2168213749","https://openalex.org/W2169960781","https://openalex.org/W2170385301","https://openalex.org/W2171011369","https://openalex.org/W2171384640","https://openalex.org/W2340830559","https://openalex.org/W4232995978","https://openalex.org/W4248356569","https://openalex.org/W4252720095"],"related_works":["https://openalex.org/W2182978714","https://openalex.org/W2113097723","https://openalex.org/W2047770999","https://openalex.org/W2182566180","https://openalex.org/W2018492687","https://openalex.org/W1832041093","https://openalex.org/W2096470960","https://openalex.org/W4386303212","https://openalex.org/W1597333775","https://openalex.org/W4410082873"],"abstract_inverted_index":{"A":[0],"largely":[1,97],"unilamellar":[2],"epithelial":[3,46,55,92,135],"layer":[4],"lines":[5],"body":[6],"cavities":[7],"and":[8,16,26,30,48,72,102,127,147,186],"organ":[9],"ducts":[10],"such":[11],"as":[12],"the":[13,84,99,121,149,167,173,181],"digestive":[14],"tract":[15],"kidney":[17,182],"tubules.":[18],"This":[19],"polarized":[20,91,134],"epithelium":[21],"is":[22,41,49,58,65,95],"composed":[23],"of":[24,45,54,74,76,83,129,152,162,175,180,191],"biochemically":[25],"functionally":[27],"separate":[28],"apical":[29,103],"basolateral":[31,100,105],"surfaces.":[32],"The":[33],"epidermal":[34],"growth":[35],"factor":[36],"receptor":[37],"(EGFR)":[38],"signaling":[39,64,194],"pathway":[40],"a":[42,52,159,188],"critical":[43],"regulator":[44],"homeostasis":[47],"perturbed":[50],"in":[51,61,81,133],"number":[53],"disorders.":[56],"It":[57],"underappreciated":[59],"that":[60,87],"vivo":[62],"EGFR":[63,94,131,168,192],"most":[66],"often":[67],"initiated":[68],"by":[69],"cell-surface":[70,123],"delivery":[71,107],"processing":[73],"one":[75],"seven":[77],"transmembrane":[78],"ligands,":[79,169],"resulting":[80],"release":[82,128],"soluble":[85,130],"form":[86],"binds":[88],"EGFR.":[89],"In":[90,113],"cells,":[93],"restricted":[96],"to":[98,119,144],"surface,":[101],"or":[104],"ligand":[106,193],"therefore":[108],"has":[109],"important":[110],"biological":[111],"consequences.":[112],"vitro":[114],"approaches":[115],"have":[116,157],"been":[117],"used":[118],"study":[120],"biosynthesis,":[122],"delivery,":[124],"proteolytic":[125],"processing,":[126],"ligands":[132],"cells.":[136],"We":[137],"review":[138],"these":[139],"results,":[140],"discuss":[141],"their":[142],"relevance":[143],"normal":[145],"physiology,":[146],"demonstrate":[148],"pathophysiological":[150],"consequences":[151],"aberrant":[153],"trafficking.":[154],"These":[155],"studies":[156],"uncovered":[158],"rich":[160],"diversity":[161],"apico-basolateral":[163],"trafficking":[164],"mechanisms":[165],"among":[166],"provided":[170],"insights":[171],"into":[172],"pathogenesis":[174],"an":[176],"inherited":[177],"magnesium-wasting":[178],"disorder":[179],"(isolated":[183],"renal":[184],"hypomagnesemia),":[185],"identified":[187],"new":[189],"mode":[190],"via":[195],"exosomes.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
