{"id":"https://openalex.org/W2116042250","doi":"https://doi.org/10.1109/isbi.2011.5872470","title":"Tissue block MRI for slice orientation-independent registration of digital histology images to ex vivo MRI of the prostate","display_name":"Tissue block MRI for slice orientation-independent registration of digital histology images to ex vivo MRI of the prostate","publication_year":2011,"publication_date":"2011-03-01","ids":{"openalex":"https://openalex.org/W2116042250","doi":"https://doi.org/10.1109/isbi.2011.5872470","mag":"2116042250"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2011.5872470","doi":"https://doi.org/10.1109/isbi.2011.5872470","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2011.5872470","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025274219","display_name":"Eli Gibson","orcid":"https://orcid.org/0000-0001-9207-7280","observed_orcids":["https://orcid.org/0000-0001-9207-7280"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Eli Gibson","raw_affiliation_strings":["Robarts Research Institute, University of Western Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute, University of Western Ontario, Canada","institution_ids":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076455125","display_name":"Cathie Crukley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Cathie Crukley","raw_affiliation_strings":["Lawson Health Research Institute, London, ONT, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute, London, ONT, Canada","institution_ids":["https://openalex.org/I131944076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071439377","display_name":"Jos\u00e9 A. G\u00f3mez","orcid":"https://orcid.org/0000-0001-8148-8308","observed_orcids":["https://orcid.org/0000-0001-8148-8308"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jose A. Gomez","raw_affiliation_strings":["Department of Pathology, University of Western Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Western Ontario, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055091318","display_name":"Madeleine Moussa","orcid":"https://orcid.org/0000-0003-4786-6226","observed_orcids":["https://orcid.org/0000-0003-4786-6226"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Madeleine Moussa","raw_affiliation_strings":["Department of Pathology, University of Western Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Western Ontario, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019768466","display_name":"Glenn S. Bauman","orcid":"https://orcid.org/0000-0002-5279-7360","observed_orcids":["https://orcid.org/0000-0002-5279-7360"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Glenn Bauman","raw_affiliation_strings":["Department of Oncology, University of Western Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, University of Western Ontario, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004966232","display_name":"Aaron Fenster","orcid":"https://orcid.org/0000-0003-3525-2788","observed_orcids":["https://orcid.org/0000-0003-3525-2788"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Aaron Fenster","raw_affiliation_strings":["Department of Medical Biophysics, University of Western Ontario, Canada","Lawson Health Research Institute, London, ONT, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biophysics, University of Western Ontario, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Lawson Health Research Institute, London, ONT, Canada","institution_ids":["https://openalex.org/I131944076"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113914224","display_name":"Aaron D. Ward","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Aaron D. Ward","raw_affiliation_strings":["Robarts Research Institute, University of Western Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute, University of Western Ontario, Canada","institution_ids":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.194,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.81850356,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"15","issue":null,"first_page":"566","last_page":"569"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11984","display_name":"Anatomy and Medical Technology","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/digital-histology","display_name":"digital histology","score":0.6579999923706055},{"id":"https://openalex.org/keywords/prostate-histology","display_name":"prostate histology","score":0.578000009059906},{"id":"https://openalex.org/keywords/image-registration","display_name":"image registration","score":0.6679999828338623},{"id":"https://openalex.org/keywords/whole-mount-histology","display_name":"whole-mount histology","score":0.7630000114440918},{"id":"https://openalex.org/keywords/ex-vivo-mri","display_name":"ex vivo MRI","score":0.7250000238418579},{"id":"https://openalex.org/keywords/target-registration-error","display_name":"target registration error","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C173974348","wikidata":"https://www.wikidata.org/wiki/Q1469893","display_name":"Fiducial marker","level":2,"score":0.8895013928413391},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.6366962194442749},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.625420868396759},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.6168301105499268},{"id":"https://openalex.org/C16345878","wikidata":"https://www.wikidata.org/wiki/Q107472979","display_name":"Orientation (vector space)","level":2,"score":0.4954160451889038},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.4665355980396271},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4328882694244385},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4258075952529907},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4169206917285919},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.39329901337623596},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37268492579460144},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.34961947798728943},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.343614399433136},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.23432093858718872},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16830530762672424},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.16496458649635315},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.11321666836738586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06473648548126221},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi.2011.5872470","doi":"https://doi.org/10.1109/isbi.2011.5872470","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2011.5872470","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1518282","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1518282/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In: (Proceedings) 8th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro. (pp. pp. 566-569). IEEE (2011)","raw_type":"Proceedings paper"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1569526137","https://openalex.org/W1817267053","https://openalex.org/W1985369125","https://openalex.org/W2005199790","https://openalex.org/W2009699040","https://openalex.org/W2023523219","https://openalex.org/W2035945901","https://openalex.org/W2045862330","https://openalex.org/W2054633472","https://openalex.org/W2086376969","https://openalex.org/W2167622944","https://openalex.org/W2168033859","https://openalex.org/W2168133848","https://openalex.org/W2329106677","https://openalex.org/W2417942735"],"related_works":["https://openalex.org/W2024729210","https://openalex.org/W2160353853","https://openalex.org/W2068890046","https://openalex.org/W54064588","https://openalex.org/W2543935410","https://openalex.org/W26482722","https://openalex.org/W6981796008","https://openalex.org/W2167622944","https://openalex.org/W1569526137","https://openalex.org/W2922373431"],"abstract_inverted_index":{"We":[0],"present":[1],"a":[2,54,84],"method":[3],"for":[4,24,104],"the":[5,18,22,105],"registration":[6,56,59,70,95,106],"of":[7,17,46,60,71,97],"whole-mount":[8],"digital":[9,61],"histology":[10,37,62],"images":[11,16,45,63,74],"to":[12,52,64,75],"ex":[13,77],"vivo":[14,78],"MR":[15,44,66,73,79],"prostate":[19,91],"that":[20],"relaxes":[21],"requirement":[23],"control":[25],"over":[26],"specimen":[27],"slicing":[28],"orientation.":[29],"The":[30],"approach":[31],"uses":[32],"extrinsic":[33],"fiducials":[34],"visible":[35],"on":[36,88],"and":[38,68,100],"MRI,":[39],"as":[40,42],"well":[41],"block":[43,65,72],"tissue":[47],"slices":[48],"after":[49],"coarse":[50],"sectioning,":[51],"support":[53],"two-stage":[55],"approach:":[57],"(1)":[58],"images,":[67],"(2)":[69],"whole-specimen":[76],"images.":[80],"This":[81],"work":[82],"presents":[83],"preliminary":[85],"quantitative":[86],"validation":[87],"4":[89],"clinical":[90],"specimens,":[92],"yielding":[93],"target":[94],"errors":[96],"0.6":[98],"mm":[99],"0.5":[101],"mm,":[102],"respectively,":[103],"stages,":[107],"measured":[108],"using":[109],"intrinsic":[110],"fiducials.":[111]},"counts_by_year":[{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}