{"id":"https://openalex.org/W2115863075","doi":"https://doi.org/10.1124/mol.113.087106","title":"Constitutive Knockout of Kalirin-7 Leads to Increased Rates of Cocaine Self-Administration","display_name":"Constitutive Knockout of Kalirin-7 Leads to Increased Rates of Cocaine Self-Administration","publication_year":2013,"publication_date":"2013-07-27","ids":{"openalex":"https://openalex.org/W2115863075","doi":"https://doi.org/10.1124/mol.113.087106","mag":"2115863075","pmid":"https://pubmed.ncbi.nlm.nih.gov/23894151","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3781382"},"language":"en","primary_location":{"id":"doi:10.1124/mol.113.087106","doi":"https://doi.org/10.1124/mol.113.087106","is_oa":true,"landing_page_url":"https://doi.org/10.1124/mol.113.087106","pdf_url":"https://molpharm.aspetjournals.org/content/molpharm/84/4/582.full.pdf","source":{"id":"https://openalex.org/S62949411","display_name":"Molecular Pharmacology","issn_l":"0026-895X","issn":["0026-895X","1521-0111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://molpharm.aspetjournals.org/content/molpharm/84/4/582.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039017085","display_name":"Drew D. Kiraly","orcid":"https://orcid.org/0000-0002-4818-5169","observed_orcids":["https://orcid.org/0000-0002-4818-5169"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Drew D. Kiraly","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033352404","display_name":"Natali E. Nemirovsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Natali E. Nemirovsky","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064896819","display_name":"Taylor P. LaRese","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taylor P. LaRese","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013062441","display_name":"Seven E. Tomek","orcid":"https://orcid.org/0000-0001-9968-3136","observed_orcids":["https://orcid.org/0000-0001-9968-3136"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seven E. Tomek","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010803765","display_name":"Stephanie L. Yahn","orcid":"https://orcid.org/0000-0003-3267-0992","observed_orcids":["https://orcid.org/0000-0003-3267-0992"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie L. Yahn","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076836999","display_name":"Michael Foster Olive","orcid":"https://orcid.org/0000-0002-2517-0351","observed_orcids":["https://orcid.org/0000-0002-2517-0351"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Foster Olive","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015706491","display_name":"Betty A. Eipper","orcid":"https://orcid.org/0000-0003-1171-5557","observed_orcids":["https://orcid.org/0000-0003-1171-5557"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Betty A. Eipper","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011997610","display_name":"Richard E. Mains","orcid":"https://orcid.org/0000-0003-1154-1331","observed_orcids":["https://orcid.org/0000-0003-1154-1331"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard E. Mains","raw_affiliation_strings":["Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.); and Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556","https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (D.D.K., T.P.L., B.A.E., R.E.M.)","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Psychology, Program in Behavioral Neuroscience (N.E.N., S.E.T., S.L.Y., M.F.O.) and Interdisciplinary Graduate Program in Neuroscience (M.F.O.), Arizona State University, Tempe, Arizona","institution_ids":["https://openalex.org/I55732556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.8411,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.64155562,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"84","issue":"4","first_page":"582","last_page":"590"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kalirin-7","display_name":"Kalirin-7","score":0.9900000095367432},{"id":"https://openalex.org/keywords/rhogef","display_name":"RhoGEF","score":0.859000027179718},{"id":"https://openalex.org/keywords/cocaine-self-administration","display_name":"cocaine self-administration","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cocaine-reinforcement","display_name":"cocaine reinforcement","score":0.5360000133514404},{"id":"https://openalex.org/keywords/nucleus-accumbens","display_name":"nucleus accumbens","score":0.8569999933242798},{"id":"https://openalex.org/keywords/dendritic-spine-dynamics","display_name":"dendritic spine dynamics","score":0.7170000076293945},{"id":"https://openalex.org/keywords/nr2b-subunit","display_name":"NR2B subunit","score":0.9039999842643738},{"id":"https://openalex.org/keywords/glutamatergic-signaling","display_name":"glutamatergic signaling","score":0.8759999871253967},{"id":"https://openalex.org/keywords/locomotor-sensitization","display_name":"locomotor sensitization","score":0.7379999756813049},{"id":"https://openalex.org/keywords/place-preference","display_name":"place preference","score":0.7440000176429749},{"id":"https://openalex.org/keywords/knockout-mice","display_name":"knockout mice","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C2776552330","wikidata":"https://www.wikidata.org/wiki/Q1476178","display_name":"Nucleus accumbens","level":3,"score":0.8386279940605164},{"id":"https://openalex.org/C174884520","wikidata":"https://www.wikidata.org/wiki/Q902079","display_name":"Dendritic spine","level":3,"score":0.7545034885406494},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.6939011216163635},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.5901364684104919},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5790975689888},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.5373489260673523},{"id":"https://openalex.org/C2780648746","wikidata":"https://www.wikidata.org/wiki/Q28208871","display_name":"Glutamatergic","level":4,"score":0.5002353191375732},{"id":"https://openalex.org/C25938499","wikidata":"https://www.wikidata.org/wiki/Q7663812","display_name":"Systemic administration","level":3,"score":0.4947173297405243},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46857738494873047},{"id":"https://openalex.org/C2778555786","wikidata":"https://www.wikidata.org/wiki/Q7448011","display_name":"Self-administration","level":2,"score":0.44670426845550537},{"id":"https://openalex.org/C35124327","wikidata":"https://www.wikidata.org/wiki/Q5159285","display_name":"Conditioned place preference","level":3,"score":0.44263580441474915},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36112070083618164},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.3532048761844635},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.33681127429008484},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2758709788322449},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.2203981578350067},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17466211318969727},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12222117185592651},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08838716149330139},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003042","descriptor_name":"Cocaine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012646","descriptor_name":"Self Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016739","descriptor_name":"Behavior, Addictive","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016739","descriptor_name":"Behavior, Addictive","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016739","descriptor_name":"Behavior, Addictive","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020662","descriptor_name":"Guanine Nucleotide Exchange Factors","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D020662","descriptor_name":"Guanine Nucleotide Exchange Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1124/mol.113.087106","doi":"https://doi.org/10.1124/mol.113.087106","is_oa":true,"landing_page_url":"https://doi.org/10.1124/mol.113.087106","pdf_url":"https://molpharm.aspetjournals.org/content/molpharm/84/4/582.full.pdf","source":{"id":"https://openalex.org/S62949411","display_name":"Molecular Pharmacology","issn_l":"0026-895X","issn":["0026-895X","1521-0111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmacology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3147869","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3781382","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:23894151","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23894151","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3781382","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3781382/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Pharmacol","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.909.1195","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.909.1195","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://molpharm.aspetjournals.org/content/84/4/582.full.pdf","raw_type":"text"},{"id":"mag:2377098997","doi":null,"is_oa":false,"landing_page_url":"https://molpharm.aspetjournals.org/content/early/2013/07/26/mol.113.087106.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1124/mol.113.087106","doi":"https://doi.org/10.1124/mol.113.087106","is_oa":true,"landing_page_url":"https://doi.org/10.1124/mol.113.087106","pdf_url":"https://molpharm.aspetjournals.org/content/molpharm/84/4/582.full.pdf","source":{"id":"https://openalex.org/S62949411","display_name":"Molecular Pharmacology","issn_l":"0026-895X","issn":["0026-895X","1521-0111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4762211081","display_name":"Metabotropic Glutamate Receptor Signaling and Extinction Learning","funder_award_id":"R01DA024355","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G5005454679","display_name":"Constructing a Conditional Kalirin Null Mouse","funder_award_id":"R21DA018274","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G7492819488","display_name":"GDP/GTP Exchange Factors: Nucleus Accumbens Plasticity","funder_award_id":"R01DA015464","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G7548097933","display_name":"Dissecting the role of one neuronal RhoGEF amongst many: the Kalirin-7 null mouse","funder_award_id":"R01DA023082","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G7948303032","display_name":"Kalirin-7 is essential in cocaine signaling: focus on nucleus accumbens","funder_award_id":"F30DA026706","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2115863075.pdf","grobid_xml":"https://content.openalex.org/works/W2115863075.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W16776597","https://openalex.org/W1563002661","https://openalex.org/W1763569714","https://openalex.org/W1790229678","https://openalex.org/W1968727599","https://openalex.org/W1968982499","https://openalex.org/W1972225113","https://openalex.org/W1973663764","https://openalex.org/W1978597334","https://openalex.org/W1978686840","https://openalex.org/W1979378767","https://openalex.org/W1982071355","https://openalex.org/W1988182239","https://openalex.org/W1991223384","https://openalex.org/W2004024823","https://openalex.org/W2006136005","https://openalex.org/W2016869935","https://openalex.org/W2019817334","https://openalex.org/W2021069596","https://openalex.org/W2021594631","https://openalex.org/W2028394334","https://openalex.org/W2041018266","https://openalex.org/W2042688689","https://openalex.org/W2047660382","https://openalex.org/W2047953158","https://openalex.org/W2055722215","https://openalex.org/W2063553542","https://openalex.org/W2066848874","https://openalex.org/W2067613093","https://openalex.org/W2069783754","https://openalex.org/W2071152706","https://openalex.org/W2073247533","https://openalex.org/W2075863805","https://openalex.org/W2081580739","https://openalex.org/W2081928115","https://openalex.org/W2084967673","https://openalex.org/W2093872376","https://openalex.org/W2094813482","https://openalex.org/W2097381477","https://openalex.org/W2098229885","https://openalex.org/W2101321887","https://openalex.org/W2103233885","https://openalex.org/W2107755617","https://openalex.org/W2107854911","https://openalex.org/W2112323466","https://openalex.org/W2118261070","https://openalex.org/W2118815158","https://openalex.org/W2121423419","https://openalex.org/W2122118862","https://openalex.org/W2125273810","https://openalex.org/W2127946577","https://openalex.org/W2134624334","https://openalex.org/W2134819361","https://openalex.org/W2137395087","https://openalex.org/W2140033867","https://openalex.org/W2141570631","https://openalex.org/W2158714548","https://openalex.org/W2174200381"],"related_works":["https://openalex.org/W2073247533","https://openalex.org/W1998581024","https://openalex.org/W2619912801","https://openalex.org/W2377098997","https://openalex.org/W7098534498","https://openalex.org/W2158714548","https://openalex.org/W1968727599","https://openalex.org/W2034660262","https://openalex.org/W7097748813","https://openalex.org/W2021069596"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}