{"id":"https://openalex.org/W2115658170","doi":"https://doi.org/10.1074/jbc.m105428200","title":"Identification of a Heregulin Binding Site in HER3 Extracellular Domain","display_name":"Identification of a Heregulin Binding Site in HER3 Extracellular Domain","publication_year":2001,"publication_date":"2001-11-01","ids":{"openalex":"https://openalex.org/W2115658170","doi":"https://doi.org/10.1074/jbc.m105428200","mag":"2115658170","pmid":"https://pubmed.ncbi.nlm.nih.gov/11555649"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m105428200","doi":"https://doi.org/10.1074/jbc.m105428200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m105428200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.m105428200","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069190265","display_name":"Elizabeth M. Singer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth Singer","raw_affiliation_strings":["Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569, USA","Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569","Howard Hughes Medical Institute, UCLA-Department of Energy Laboratory of Structural Biology and Molecular Medicine, Los Angeles, California 90095-1570"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, UCLA-Department of Energy Laboratory of Structural Biology and Molecular Medicine, Los Angeles, California 90095-1570","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051003679","display_name":"Ralf Landgraf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ralf Landgraf","raw_affiliation_strings":["Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90095"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90095","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111432106","display_name":"Tom Horan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tom Horan","raw_affiliation_strings":["Amgen Inc., Amgen Center, Thousand Oaks, California 91320"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen Inc., Amgen Center, Thousand Oaks, California 91320","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015491002","display_name":"Dennis J. Slamon","orcid":"https://orcid.org/0000-0002-6330-498X","observed_orcids":["https://orcid.org/0000-0002-6330-498X"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis Slamon","raw_affiliation_strings":["Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90095"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90095","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080439570","display_name":"David S Eisenberg","orcid":"https://orcid.org/0000-0003-2432-5419","observed_orcids":["https://orcid.org/0000-0003-2432-5419"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David Eisenberg","raw_affiliation_strings":["Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569","Howard Hughes Medical Institute, UCLA-Department of Energy Laboratory of Structural Biology and Molecular Medicine, Los Angeles, California 90095-1570"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095-1569","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, UCLA-Department of Energy Laboratory of Structural Biology and Molecular Medicine, Los Angeles, California 90095-1570","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5080439570"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I161318765"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.3993,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.80898499,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"276","issue":"47","first_page":"44266","last_page":"44274"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/her3","display_name":"HER3","score":0.9959999918937683},{"id":"https://openalex.org/keywords/neuregulin-1","display_name":"neuregulin-1","score":0.8130000233650208},{"id":"https://openalex.org/keywords/ligand-binding-site","display_name":"ligand binding sites","score":0.8109999895095825},{"id":"https://openalex.org/keywords/extracellular-domain","display_name":"extracellular domain","score":0.8090000152587891},{"id":"https://openalex.org/keywords/egf-like-domain","display_name":"EGF-like domain","score":0.8659999966621399},{"id":"https://openalex.org/keywords/limited-proteolysis","display_name":"limited proteolysis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/igf-1-receptor","display_name":"IGF-1 receptor","score":0.7839999794960022},{"id":"https://openalex.org/keywords/receptor-structure","display_name":"receptor structure","score":0.6269999742507935},{"id":"https://openalex.org/keywords/ligand-binding","display_name":"ligand binding","score":0.47099998593330383}],"concepts":[{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.6112516522407532},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.5478966236114502},{"id":"https://openalex.org/C118892022","wikidata":"https://www.wikidata.org/wiki/Q7834587","display_name":"Transmembrane domain","level":3,"score":0.44023048877716064},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.4296955466270447},{"id":"https://openalex.org/C2781307694","wikidata":"https://www.wikidata.org/wiki/Q33123","display_name":"Proteolysis","level":3,"score":0.41573044657707214},{"id":"https://openalex.org/C2776362946","wikidata":"https://www.wikidata.org/wiki/Q424374","display_name":"Epidermal growth factor","level":3,"score":0.4111217260360718},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4005606770515442},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3622526526451111},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33770036697387695},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27696359157562256},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08087900280952454}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016466","descriptor_name":"CHO Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020794","descriptor_name":"Receptor Protein-Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020794","descriptor_name":"Receptor Protein-Tyrosine Kinases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020890","descriptor_name":"Neuregulin-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.m105428200","doi":"https://doi.org/10.1074/jbc.m105428200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m105428200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:11555649","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11555649","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m105428200","doi":"https://doi.org/10.1074/jbc.m105428200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m105428200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1543282891","display_name":null,"funder_award_id":"CA-16 042","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000898870","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016042","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W597159688","https://openalex.org/W1488828742","https://openalex.org/W1500256341","https://openalex.org/W1502793952","https://openalex.org/W1527342612","https://openalex.org/W1600454185","https://openalex.org/W1631405381","https://openalex.org/W1672544146","https://openalex.org/W1757206865","https://openalex.org/W1812775185","https://openalex.org/W1893360284","https://openalex.org/W1967647423","https://openalex.org/W1979925668","https://openalex.org/W1981723679","https://openalex.org/W1985960183","https://openalex.org/W1991224892","https://openalex.org/W1995337883","https://openalex.org/W2001124278","https://openalex.org/W2001641653","https://openalex.org/W2002908987","https://openalex.org/W2004360551","https://openalex.org/W2008940139","https://openalex.org/W2014111401","https://openalex.org/W2018771305","https://openalex.org/W2025561101","https://openalex.org/W2032359283","https://openalex.org/W2034999801","https://openalex.org/W2036387229","https://openalex.org/W2045492296","https://openalex.org/W2048905477","https://openalex.org/W2054698853","https://openalex.org/W2059603894","https://openalex.org/W2062080999","https://openalex.org/W2076104903","https://openalex.org/W2076492088","https://openalex.org/W2077630059","https://openalex.org/W2081191736","https://openalex.org/W2086624267","https://openalex.org/W2092429540","https://openalex.org/W2095156669","https://openalex.org/W2103174300","https://openalex.org/W2122788299","https://openalex.org/W2134570388","https://openalex.org/W2141393790","https://openalex.org/W2143210482","https://openalex.org/W2157855496","https://openalex.org/W4245201632"],"related_works":["https://openalex.org/W1870193477","https://openalex.org/W2014891977","https://openalex.org/W2014160379","https://openalex.org/W1488828742","https://openalex.org/W3004483215","https://openalex.org/W1992821829","https://openalex.org/W2064398565","https://openalex.org/W1982627339","https://openalex.org/W2157855496","https://openalex.org/W1978343870"],"abstract_inverted_index":{"HER3":[0,113,319],"(also":[1],"known":[2],"as":[3,189,220,280,282,304,307],"c-Erb-b3)":[4],"is":[5,129,211,255,275],"a":[6,83,99,157,190,231,244,305,321,330],"type":[7,292],"I":[8,33,65,155,164,183,236,254],"receptor":[9,28,218],"tyrosine":[10],"kinase":[11],"similar":[12,37,212,323],"in":[13,38,70,115,193,227,234,257,288,332],"sequence":[14,39],"to":[15,40,63,72,143,213,230,324],"the":[16,56,73,108,117,124,135,204,214,250,262,283,316],"epidermal":[17],"growth":[18,216],"factor":[19],"(EGF)":[20],"receptor.":[21],"The":[22,223],"extracellular":[23,110],"segment":[24],"of":[25,59,68,86,91,107,112,121,126,137,141,186,197,207,237,269,272,285,291,301],"this":[26,289],"transmembrane":[27],"contains":[29,156],"four":[30],"domains.":[31,334],"Domains":[32],"and":[34,43,46,49,66,89,119,165,168,184,195,260,299,326],"II":[35,48,67,166,185],"are":[36,51,313],"domains":[41,47,64,87,111,163,182,297],"III":[42,88],"IV,":[44],"respectively,":[45],"IV":[50,93],"cysteine-rich.":[52],"We":[53],"show":[54],"that":[55,82,153,170,181,209,252,274,296,318],"EGF-like":[57],"domain":[58,92,138,154,235,253,270,278],"heregulin":[60],"(hrg)":[61],"binds":[62,94,172,241,327],"HER3,":[69],"contrast":[71],"EGF":[74],"receptor,":[75],"for":[76,309],"which":[77],"prior":[78],"studies":[79],"have":[80],"shown":[81],"construct":[84],"consisting":[85],"portions":[90],"EGF.":[95],"Next,":[96],"we":[97,161],"identified":[98],"putative":[100],"hrg":[101,142,158,173,242],"binding":[102,159,196,232],"site":[103,226,331],"by":[104,277],"limited":[105],"proteolysis":[106],"recombinant":[109],"(HER3-ECD(I-IV))":[114],"both":[116],"presence":[118,284],"absence":[120,125],"hrg.":[122,198],"In":[123],"hrg,":[127],"HER3-ECD(I-IV)":[128,144,187,210,228],"cleaved":[130],"after":[131],"position":[132,147],"Tyr(50),":[133],"near":[134],"beginning":[136],"I.":[139],"Binding":[140],"fully":[145],"protects":[146],"Tyr(50)":[148],"from":[149],"proteolysis.":[150],"To":[151],"confirm":[152],"site,":[160],"expressed":[162],"(HER3-ECD(I-II))":[167],"find":[169],"it":[171],"with":[174,243,315],"68":[175,245],"nm":[176,246],"affinity.":[177],"These":[178],"data":[179],"suggest":[180],"act":[188],"functional":[191],"unit":[192,306],"folding":[194],"Thus,":[199],"our":[200],"biochemical":[201],"findings":[202],"reinforce":[203],"structural":[205],"hypothesis":[206,251],"others":[208],"insulin-like":[215],"factor-1":[217],"(IGF-1R),":[219],"follows:":[221],"1)":[222],"protected":[224],"cleavage":[225],"corresponds":[229],"footprint":[233],"IGF-1R;":[238],"2)":[239],"HER3-ECD(I-II)":[240],"dissociation":[247],"constant,":[248],"supporting":[249],"involved":[256],"ligand":[258,328],"binding;":[259],"3)":[261],"large":[263],"accessible":[264],"surface":[265],"area":[266],"(1749":[267],"A)":[268],"L1":[271,298],"IGF-1R":[273,302,325],"buried":[276],"S1,":[279],"well":[281],"conserved":[286],"contacts":[287],"interface":[290],"1":[293],"RTKs,":[294],"suggests":[295],"S1":[300],"function":[303],"observed":[308],"HER3-ECD(I-II).":[310],"Our":[311],"results":[312],"consistent":[314],"proposal":[317],"has":[320],"structure":[322],"at":[329],"corresponding":[333]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}