{"id":"https://openalex.org/W2115192091","doi":"https://doi.org/10.1212/wnl.0b013e31821e54b3","title":"Serum adipocyte fatty acid\u2013binding protein associated with ischemic stroke and early death","display_name":"Serum adipocyte fatty acid\u2013binding protein associated with ischemic stroke and early death","publication_year":2011,"publication_date":"2011-05-12","ids":{"openalex":"https://openalex.org/W2115192091","doi":"https://doi.org/10.1212/wnl.0b013e31821e54b3","mag":"2115192091","pmid":"https://pubmed.ncbi.nlm.nih.gov/21562251"},"language":"en","primary_location":{"id":"doi:10.1212/wnl.0b013e31821e54b3","doi":"https://doi.org/10.1212/wnl.0b013e31821e54b3","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.0b013e31821e54b3","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110030985","display_name":"Annette W.K. Tso","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A.W.K. Tso","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104147641","display_name":"T.K. Lam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T.K.Y. Lam","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031014820","display_name":"Aimin Xu","orcid":"https://orcid.org/0000-0002-0668-033X","observed_orcids":["https://orcid.org/0000-0002-0668-033X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Xu","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109590017","display_name":"Kai\u2010Hang Yiu","orcid":"https://orcid.org/0000-0003-2145-3108","observed_orcids":["https://orcid.org/0000-0003-2145-3108","https://orcid.org/0000-0001-6430-9662"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K.H. Yiu","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065770366","display_name":"Hung\u2010Fat Tse","orcid":"https://orcid.org/0000-0002-9578-7808","observed_orcids":["https://orcid.org/0000-0002-9578-7808"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H.F. Tse","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058648874","display_name":"L.S.W. Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L.S.W. Li","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036200462","display_name":"Lawrence Siu\u2010Chun Law","orcid":"https://orcid.org/0000-0002-0429-2632","observed_orcids":["https://orcid.org/0000-0002-0429-2632"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L.S.C. Law","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113918967","display_name":"Bernard M.Y. Cheung","orcid":"https://orcid.org/0000-0001-9106-7363","observed_orcids":["https://orcid.org/0000-0001-9106-7363"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B.M.Y. Cheung","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109327771","display_name":"Rtf Cheung","orcid":"https://orcid.org/0009-0000-8719-5856","observed_orcids":["https://orcid.org/0009-0000-8719-5856"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R.T.F. Cheung","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112489379","display_name":"Karen S.L. Lam","orcid":"https://orcid.org/0000-0001-5757-541X","observed_orcids":["https://orcid.org/0000-0001-5757-541X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K.S.L. Lam","raw_affiliation_strings":["From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine (A.W.K.T., T.K.Y.L., A.X., K.H.Y., H.F.T., L.S.C.L., B.M.Y.C., R.T.F.C., K.S.L.L.), Queen Mary Hospital; Research Centre of Heart, Brain, Hormone and Healthy Aging (A.W.K.T., A.X., H.F.T., R.T.F.C., K.S.L.L.) and Department of Pharmacology (A.X.), Li Ka Shing Faculty of Medicine; and The University of Hong Kong and Department of Medicine (L.S.W.L.), Tung Wah Hospital, Hong Kong","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.7244,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.95297086,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"76","issue":"23","first_page":"1968","last_page":"1975"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.8521000146865845,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.8521000146865845,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.08799999952316284,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.03139999881386757,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adipocyte-fatty-acid-binding-protein","display_name":"adipocyte fatty acid-binding protein","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9679999947547913},{"id":"https://openalex.org/keywords/early-mortality","display_name":"early mortality","score":0.8640000224113464},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.6349999904632568},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7400000095367432},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.9160000085830688},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.8420000076293945},{"id":"https://openalex.org/keywords/acute-stroke","display_name":"acute stroke","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7759565114974976},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.741270899772644},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.634523868560791},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6263404488563538},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.5643758773803711},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.5413496494293213},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5344874858856201},{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.5165109038352966},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5155972838401794},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4880272448062897},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.36681634187698364},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36176806688308716},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.35126957297325134},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.13571491837501526},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D050556","descriptor_name":"Fatty Acid-Binding Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1212/wnl.0b013e31821e54b3","doi":"https://doi.org/10.1212/wnl.0b013e31821e54b3","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.0b013e31821e54b3","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},{"id":"pmid:21562251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21562251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"Journal Article"},{"id":"pmh:oai:hub.hku.hk:10722/129286","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10722/129286","pdf_url":null,"source":{"id":"https://openalex.org/S4377196271","display_name":"The HKU Scholars Hub (University of Hong Kong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I889458895","host_organization_name":"University of Hong Kong","host_organization_lineage":["https://openalex.org/I889458895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1577139444","https://openalex.org/W1925840058","https://openalex.org/W1974075370","https://openalex.org/W1975543439","https://openalex.org/W1999290243","https://openalex.org/W2001471462","https://openalex.org/W2007106585","https://openalex.org/W2045806619","https://openalex.org/W2054066234","https://openalex.org/W2060952287","https://openalex.org/W2067187286","https://openalex.org/W2067919004","https://openalex.org/W2080504768","https://openalex.org/W2081705352","https://openalex.org/W2089797837","https://openalex.org/W2102903050","https://openalex.org/W2103633907","https://openalex.org/W2108036042","https://openalex.org/W2112861216","https://openalex.org/W2113570079","https://openalex.org/W2115460318","https://openalex.org/W2130234373","https://openalex.org/W2132401640","https://openalex.org/W2133374684","https://openalex.org/W2137919142","https://openalex.org/W2146000754","https://openalex.org/W2147654254","https://openalex.org/W2159243939","https://openalex.org/W2166077943","https://openalex.org/W2169500518","https://openalex.org/W2169970290","https://openalex.org/W2181432118","https://openalex.org/W2185461071","https://openalex.org/W2345903479"],"related_works":["https://openalex.org/W3028795784","https://openalex.org/W2016947779","https://openalex.org/W3171814611","https://openalex.org/W2744663105","https://openalex.org/W1984903997","https://openalex.org/W2737676476","https://openalex.org/W2938812287","https://openalex.org/W1972102243","https://openalex.org/W2612473359","https://openalex.org/W3031619580"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Adipocyte":[1],"fatty":[2],"acid-binding":[3],"protein":[4],"(A-FABP)":[5],"is":[6],"an":[7],"adipokine":[8],"shown":[9],"to":[10,19,32,117,193],"have":[11],"adverse":[12],"metabolic":[13],"and":[14,17,49,70,74,130,166,183,229,247],"proinflammatory":[15],"effects,":[16],"contributes":[18],"atherosclerosis":[20],"in":[21,26,29,63,91,110,128,140,214,243],"mice.":[22],"However,":[23],"its":[24,51],"role":[25],"cardiovascular":[27,84],"diseases":[28],"humans":[30],"remains":[31],"be":[33],"established.":[34],"In":[35],"this":[36],"case-control":[37,245],"study,":[38,246],"we":[39],"investigated":[40],"the":[41,151,184],"association":[42,52],"of":[43,83,102,186,227],"serum":[44,168,206],"A-FABP":[45,58,87,107,169,187,207,236],"with":[46,53,66,112,150,173,188,210,240],"ischemic":[47,68,94,113,189,215,241],"stroke,":[48],"examined":[50],"early":[54,256],"mortality.":[55,257],"METHODS:":[56],"Serum":[57,86,106,235],"was":[59,88,108,170,208,237],"measured,":[60],"using":[61],"ELISA,":[62],"306":[64,71],"subjects":[65,96,111,217],"acute":[67,103],"stroke":[69,95,114,142,174,190,216,242],"age-,":[72],"sex-,":[73],"body":[75],"mass":[76],"index-matched":[77],"controls.":[78],"All":[79],"controls":[80,118],"were":[81,191],"free":[82],"diseases.":[85],"also":[89],"measured":[90],"another":[92],"60":[93],"who":[97],"died":[98],"within":[99],"3":[100],"months":[101],"stroke.":[104],"RESULTS:":[105],"higher":[109],"as":[115,197,250],"compared":[116],"(19.6":[119],"ng/mL":[120,125,132,137],"[14.3-28.4":[121],"ng/mL]":[122,127,134,139],"vs":[123,135,143],"15.2":[124],"[10.6-23.6":[126],"men":[129],"32.4":[131],"[24.5-45.7":[133],"22.0":[136],"[14.3-34.0":[138],"women,":[141],"control,":[144],"p<0.001).":[145],"On":[146],"logistic":[147],"regression":[148],"analyses":[149],"model":[152],"including":[153],"hypertension,":[154],"diabetes,":[155],"high-density":[156],"lipoprotein":[157,160],"cholesterol,":[158,161],"low-density":[159],"triglyceride,":[162],"lipid-lowering":[163],"treatment,":[164],"smoking,":[165],"A-FABP,":[167],"independently":[171],"associated":[172,209,239],"(odds":[175,218],"ratio":[176,201,219],"2.10,":[177],"95%":[178,221],"confidence":[179,222],"interval":[180,223],"1.50-2.94,":[181],"p<0.001),":[182],"associations":[185],"additive":[192],"conventional":[194],"risk":[195],"factors,":[196],"demonstrated":[198],"on":[199],"likelihood":[200],"tests":[202],"(p<0.001).":[203],"Furthermore,":[204],"high":[205],"increased":[211],"3-month":[212],"mortality":[213],"2.65,":[220],"1.18-5.96,":[224],"p=0.018),":[225],"independent":[226],"age":[228],"NIH":[230],"Stroke":[231],"Scale":[232],"score.":[233],"CONCLUSIONS:":[234],"significantly":[238],"our":[244],"may":[248],"serve":[249],"a":[251],"useful":[252],"prognostic":[253],"indicator":[254],"for":[255]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}