{"id":"https://openalex.org/W2115181996","doi":null,"title":"Obstructive sleep apnoea: definitions, epidemiology & natural history.","display_name":"Obstructive sleep apnoea: definitions, epidemiology & natural history.","publication_year":2010,"publication_date":"2010-02-01","ids":{"openalex":"https://openalex.org/W2115181996","mag":"2115181996","pmid":"https://pubmed.ncbi.nlm.nih.gov/20308741"},"language":"en","primary_location":{"id":"pmid:20308741","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20308741","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103582122","display_name":"Jamie Lam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800810863","display_name":"Queen Mary Hospital","ror":"https://ror.org/02xkx3e48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I2800810863"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Jamie C M Lam","raw_affiliation_strings":["University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, SAR, China","institution_ids":["https://openalex.org/I2800810863","https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110325603","display_name":"Surendra Kumar Sharma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S K Sharma","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113666711","display_name":"BING K. LAM","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bing Lam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.676,"has_fulltext":false,"cited_by_count":152,"citation_normalized_percentile":{"value":0.96616888,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"131","issue":null,"first_page":"165","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9990000128746033},{"id":"https://openalex.org/keywords/epidemiology","display_name":"epidemiology","score":0.7760000228881836},{"id":"https://openalex.org/keywords/natural-history-disease","display_name":"natural history (disease)","score":0.890999972820282},{"id":"https://openalex.org/keywords/upper-airway-collapse","display_name":"upper airway collapse","score":0.8460000157356262},{"id":"https://openalex.org/keywords/sleep-fragmentation","display_name":"sleep fragmentation","score":0.7519999742507935},{"id":"https://openalex.org/keywords/cardiometabolic-risk","display_name":"cardiometabolic risk","score":0.8040000200271606},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9010000228881836},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9620000123977661},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9160000085830688},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.9279999732971191},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.800000011920929},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.7979999780654907},{"id":"https://openalex.org/keywords/snoring","display_name":"snoring","score":0.9539999961853027},{"id":"https://openalex.org/keywords/excessive-daytime-sleepiness","display_name":"excessive daytime sleepiness","score":0.9169999957084656},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.42100000381469727}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.868466854095459},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6131014823913574},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6101558804512024},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.533537745475769},{"id":"https://openalex.org/C163276114","wikidata":"https://www.wikidata.org/wiki/Q484591","display_name":"Natural history","level":2,"score":0.49820661544799805},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.4745959937572479},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.46830856800079346},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4627061188220978},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.45826631784439087},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.4561440646648407},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4543553590774536},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4495016634464264},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3540085554122925},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3439558744430542},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2842322885990143},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0815322995185852},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006970","descriptor_name":"Disorders of Excessive Somnolence","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D045422","descriptor_name":"Continuous Positive Airway Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:20308741","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20308741","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},{"id":"mag:2115181996","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20308741","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W185503309","https://openalex.org/W1595524929","https://openalex.org/W1714259827","https://openalex.org/W1766014061","https://openalex.org/W1964192238","https://openalex.org/W1970596096","https://openalex.org/W1972056446","https://openalex.org/W1984921150","https://openalex.org/W1988802440","https://openalex.org/W1992545920","https://openalex.org/W1994263114","https://openalex.org/W1996692474","https://openalex.org/W2007726540","https://openalex.org/W2021155493","https://openalex.org/W2026191693","https://openalex.org/W2028123491","https://openalex.org/W2031374244","https://openalex.org/W2033770922","https://openalex.org/W2034556696","https://openalex.org/W2040200909","https://openalex.org/W2051344677","https://openalex.org/W2057023498","https://openalex.org/W2058094140","https://openalex.org/W2063135200","https://openalex.org/W2063964681","https://openalex.org/W2066990400","https://openalex.org/W2079556915","https://openalex.org/W2082694529","https://openalex.org/W2087380614","https://openalex.org/W2094748343","https://openalex.org/W2100919087","https://openalex.org/W2101072429","https://openalex.org/W2105531045","https://openalex.org/W2111511760","https://openalex.org/W2113982368","https://openalex.org/W2114776577","https://openalex.org/W2130340796","https://openalex.org/W2133329873","https://openalex.org/W2143959552","https://openalex.org/W2144194006","https://openalex.org/W2148345618","https://openalex.org/W2153074168","https://openalex.org/W2155840283","https://openalex.org/W2163889059","https://openalex.org/W2333343699"],"related_works":["https://openalex.org/W2913723470","https://openalex.org/W2257806081","https://openalex.org/W4406874763","https://openalex.org/W2021128185","https://openalex.org/W2185288152","https://openalex.org/W2363847837","https://openalex.org/W2124231622","https://openalex.org/W2145530951","https://openalex.org/W4318612444","https://openalex.org/W2896397916"],"abstract_inverted_index":{"Obstructive":[0],"sleep":[1,37,41,99,155,171,186],"apnoea":[2,100,172,187],"(OSA)":[3],"is":[4,21,44,49],"increasingly":[5],"being":[6,50],"recognized":[7],"as":[8,52],"an":[9,53],"important":[10],"health":[11,177],"issue":[12],"in":[13,83,146,188],"the":[14,84,94,133,181],"last":[15],"two":[16],"to":[17,69,88,131,154],"three":[18],"decades.":[19],"It":[20],"characterized":[22],"by":[23],"frequent":[24],"episodes":[25],"of":[26,78,86,139,169,180,184],"upper":[27],"airway":[28],"collapse":[29],"during":[30],"sleep,":[31],"causing":[32],"recurrent":[33],"arousals,":[34],"intermittent":[35],"hypoxaemia,":[36],"fragmentation":[38],"and":[39,66,73,93,112,125,143,162,167],"poor":[40],"quality.":[42],"There":[43],"accumulating":[45],"evidence":[46],"that":[47],"OSA":[48,79],"considered":[51],"independent":[54],"risk":[55,95],"factor":[56],"for":[57,97,159],"hypertension,":[58],"glucose":[59],"intolerance":[60],"/":[61],"diabetes":[62],"mellitus,":[63],"cardiovascular":[64],"diseases":[65],"stroke,":[67],"leading":[68],"increased":[70,152],"cardiometabolic":[71],"morbidity":[72],"mortality.":[74],"The":[75,115],"prevalence":[76],"rates":[77],"have":[80,150],"been":[81,151],"estimated":[82],"range":[85],"2":[87],"10":[89],"per":[90],"cent":[91],"worldwide,":[92],"factors":[96],"obstructive":[98,170,185],"include":[101],"advanced":[102],"age,":[103],"male":[104],"sex,":[105],"obesity,":[106],"family":[107],"history,":[108],"craniofacial":[109],"abnormalities,":[110],"smoking":[111],"alcohol":[113],"consumption.":[114],"common":[116],"clinical":[117],"presenting":[118],"symptoms":[119],"are":[120,190],"heavy":[121],"snoring,":[122],"witnessed":[123],"apnoeas":[124],"daytime":[126],"hypersomnolence,":[127],"which":[128],"would":[129],"help":[130],"identify":[132],"affected":[134],"individuals.":[135],"With":[136],"increasing":[137],"awareness":[138],"this":[140],"disease":[141],"entity":[142],"associated":[144],"complications":[145],"our":[147],"society,":[148],"there":[149],"referrals":[153],"physicians":[156],"or":[157],"expertise":[158],"further":[160],"investigations":[161],"diagnostic":[163],"evaluation.":[164],"Early":[165],"recognition":[166],"treatment":[168],"may":[173],"prevent":[174],"from":[175],"adverse":[176],"consequences.":[178],"Some":[179],"epidemiological":[182],"aspects":[183],"adults":[189],"reviewed.":[191]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":25},{"year":2014,"cited_by_count":29},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}