{"id":"https://openalex.org/W2114967331","doi":"https://doi.org/10.1128/jb.178.16.4909-4918.1996","title":"Porin activity of the native and recombinant outer membrane protein Oms28 of Borrelia burgdorferi","display_name":"Porin activity of the native and recombinant outer membrane protein Oms28 of Borrelia burgdorferi","publication_year":1996,"publication_date":"1996-08-01","ids":{"openalex":"https://openalex.org/W2114967331","doi":"https://doi.org/10.1128/jb.178.16.4909-4918.1996","mag":"2114967331","pmid":"https://pubmed.ncbi.nlm.nih.gov/8759855","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/178274"},"language":"en","primary_location":{"id":"doi:10.1128/jb.178.16.4909-4918.1996","doi":"https://doi.org/10.1128/jb.178.16.4909-4918.1996","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.178.16.4909-4918.1996","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/178274","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067154316","display_name":"Jon T. Skare","orcid":"https://orcid.org/0000-0001-8378-7862","observed_orcids":["https://orcid.org/0000-0001-8378-7862"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J T Skare","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053972016","display_name":"C I Champion","orcid":"https://orcid.org/0009-0005-9854-0789","observed_orcids":["https://orcid.org/0009-0005-9854-0789"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C I Champion","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044444578","display_name":"Tajib A. Mirzabekov","orcid":"https://orcid.org/0000-0001-8727-9208","observed_orcids":["https://orcid.org/0000-0001-8727-9208"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T A Mirzabekov","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113698733","display_name":"E S Shang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E S Shang","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073236121","display_name":"D R Blanco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D R Blanco","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082796663","display_name":"Hediye Erdjument\u2010Bromage","orcid":"https://orcid.org/0000-0003-0224-3594","observed_orcids":["https://orcid.org/0000-0003-0224-3594"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H Erdjument-Bromage","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009347072","display_name":"Paul Tempst","orcid":"https://orcid.org/0000-0002-6680-3987","observed_orcids":["https://orcid.org/0000-0002-6680-3987"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P Tempst","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010601422","display_name":"Bruce L. Kagan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B L Kagan","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087235304","display_name":"James N. Miller","orcid":"https://orcid.org/0000-0002-4737-2608","observed_orcids":["https://orcid.org/0000-0002-4737-2608"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J N Miller","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042068923","display_name":"Michael Lovett","orcid":"https://orcid.org/0000-0002-6510-5829","observed_orcids":["https://orcid.org/0000-0002-6510-5829"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M A Lovett","raw_affiliation_strings":["Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, UCLA School of Medicine 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":null,"apc_paid":null,"fwci":2.6824,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.89329651,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"178","issue":"16","first_page":"4909","last_page":"4918"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.9028000235557556,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.9028000235557556,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.05999999865889549,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/borrelia-burgdorferi","display_name":"Borrelia burgdorferi","score":0.996999979019165},{"id":"https://openalex.org/keywords/porin","display_name":"porin","score":0.6779999732971191},{"id":"https://openalex.org/keywords/outer-membrane-proteins","display_name":"outer membrane proteins","score":0.9279999732971191},{"id":"https://openalex.org/keywords/outer-membrane-vesicles","display_name":"outer membrane vesicles","score":0.972000002861023},{"id":"https://openalex.org/keywords/single-channel-conductance","display_name":"single-channel conductance","score":0.8600000143051147},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.8190000057220459},{"id":"https://openalex.org/keywords/signal-peptide","display_name":"signal peptide","score":0.5540000200271606},{"id":"https://openalex.org/keywords/lyme-disease","display_name":"Lyme disease","score":0.921999990940094},{"id":"https://openalex.org/keywords/gene-cloning","display_name":"gene cloning","score":0.3880000114440918}],"concepts":[{"id":"https://openalex.org/C2777317804","wikidata":"https://www.wikidata.org/wiki/Q67101192","display_name":"Porin","level":5,"score":0.9485702514648438},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8385661840438843},{"id":"https://openalex.org/C2779159148","wikidata":"https://www.wikidata.org/wiki/Q2723634","display_name":"Borrelia burgdorferi","level":3,"score":0.7815487384796143},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.7777434587478638},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.5814089179039001},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5614104270935059},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.538192093372345},{"id":"https://openalex.org/C50476208","wikidata":"https://www.wikidata.org/wiki/Q898861","display_name":"Isoelectric focusing","level":3,"score":0.5349088907241821},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4953066408634186},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.4826643764972687},{"id":"https://openalex.org/C116084860","wikidata":"https://www.wikidata.org/wiki/Q48255","display_name":"Gel electrophoresis","level":2,"score":0.4822995662689209},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.47445282340049744},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.423662930727005},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.16928702592849731},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1396687924861908},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.076814204454422},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015748","descriptor_name":"Borrelia burgdorferi Group","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015748","descriptor_name":"Borrelia burgdorferi Group","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018272","descriptor_name":"Porins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D018272","descriptor_name":"Porins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D018272","descriptor_name":"Porins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1128/jb.178.16.4909-4918.1996","doi":"https://doi.org/10.1128/jb.178.16.4909-4918.1996","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.178.16.4909-4918.1996","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:178274","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/178274","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},{"id":"pmid:8759855","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8759855","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bacteriology","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.330.5547","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.330.5547","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jb.asm.org/content/178/16/4909.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:178274","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/178274","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1017893245","display_name":null,"funder_award_id":"AI21352","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G187230835","display_name":"GENETICS OF TREPONEMA PALLIDUM PATHOGENICITY","funder_award_id":"2r01ai021352-08","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3469142691","display_name":"Pathogenic Mechanisms in Lyme Borreliosis","funder_award_id":"R01AI029733","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5427012665","display_name":null,"funder_award_id":"AI-37312","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6138257050","display_name":"LYME DISEASE MODEL--PATHOGENESIS AND IMMUNITY","funder_award_id":"R01AI037312","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G63239148","display_name":null,"funder_award_id":"AI 29733","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W171398818","https://openalex.org/W1493074386","https://openalex.org/W1562400216","https://openalex.org/W1564563877","https://openalex.org/W1703676865","https://openalex.org/W1877825715","https://openalex.org/W1910376298","https://openalex.org/W1921249079","https://openalex.org/W1940543181","https://openalex.org/W1967110222","https://openalex.org/W1974821195","https://openalex.org/W1983831412","https://openalex.org/W1997698750","https://openalex.org/W1999500526","https://openalex.org/W2013005355","https://openalex.org/W2016216159","https://openalex.org/W2018289835","https://openalex.org/W2018922535","https://openalex.org/W2020652394","https://openalex.org/W2055043387","https://openalex.org/W2073941667","https://openalex.org/W2078186315","https://openalex.org/W2079699903","https://openalex.org/W2100775273","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2101342364","https://openalex.org/W2103306238","https://openalex.org/W2104334002","https://openalex.org/W2117007857","https://openalex.org/W2117257030","https://openalex.org/W2120821581","https://openalex.org/W2127912916","https://openalex.org/W2129328541","https://openalex.org/W2138270253","https://openalex.org/W2144634347","https://openalex.org/W2151603494","https://openalex.org/W2158019552","https://openalex.org/W2160107586","https://openalex.org/W2160731892","https://openalex.org/W2161018980","https://openalex.org/W2167415399","https://openalex.org/W2167670136","https://openalex.org/W2171601523","https://openalex.org/W2323010758","https://openalex.org/W2325020298","https://openalex.org/W2401277955","https://openalex.org/W3016385149","https://openalex.org/W4232462786","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1857832081","https://openalex.org/W2170455757","https://openalex.org/W2028409160","https://openalex.org/W2096608823","https://openalex.org/W1997698750","https://openalex.org/W2104334002","https://openalex.org/W2019074098","https://openalex.org/W3163229426","https://openalex.org/W2062885416","https://openalex.org/W2006080034"],"abstract_inverted_index":{"The":[0,79,90],"outer":[1,30,138],"membrane-spanning":[2],"(Oms)":[3],"proteins":[4],"of":[5,27,40,95,122,159,192,199],"Borrelia":[6],"burgdorferi":[7,29,176],"have":[8],"been":[9],"visualized":[10],"by":[11,154],"freeze-fracture":[12],"analysis":[13],"but,":[14],"until":[15],"recently,":[16],"not":[17],"further":[18],"characterized.":[19],"We":[20],"developed":[21],"a":[22,74,98,103,114,118,174],"method":[23],"for":[24],"the":[25,68,130,137,163,178,190,197,200],"isolation":[26],"B.":[28,175],"membrane":[31],"vesicles":[32],"and":[33,42,57,84,195],"described":[34],"porin":[35,70,132],"activities":[36],"with":[37,102,117],"single-channel":[38,157],"conductances":[39],"0.6":[41],"12.6":[43],"nS":[44,161],"in":[45,73,127,134,162],"1":[46],"M":[47],"KCI.":[48],"By":[49],"using":[50],"both":[51],"nondenaturing":[52],"isoelectric":[53],"focusing":[54],"gel":[55],"electrophoresis":[56],"fast-performance":[58],"liquid":[59],"chromatography":[60],"separation":[61],"after":[62],"detergent":[63],"solubilization,":[64],"we":[65],"found":[66],"that":[67,171],"0.6-nS":[69],"activity":[71,151],"resided":[72],"28-kDa":[75],"protein,":[76],"designated":[77],"Oms28.":[78],"oms28":[80],"gene":[81],"was":[82,88],"cloned,":[83],"its":[85],"nucleotide":[86],"sequence":[87,94],"determined.":[89],"deduced":[91],"amino":[92],"acid":[93],"Oms28":[96,112,131,145,172],"predicted":[97,119],"257-amino-acid":[99],"precursor":[100],"protein":[101,116],"putative":[104],"24-amino-acid":[105],"leader":[106],"peptidase":[107],"I":[108],"signal":[109],"sequence.":[110],"Processed":[111],"yielded":[113],"mature":[115],"molecular":[120],"mass":[121],"25,363":[123],"Da.":[124],"When":[125],"overproduced":[126],"Escherichia":[128],"coli,":[129],"fractionated":[133],"part":[135],"to":[136,180,189,196],"membrane.":[139],"Sodium":[140],"dodecyl":[141],"sulfate-polyacrylamide":[142],"gel-purified":[143],"recombinant":[144],"from":[146],"E.":[147],"coli":[148],"retained":[149],"functional":[150],"as":[152],"demonstrated":[153],"an":[155],"average":[156],"conductance":[158],"1.1":[160],"planar":[164],"lipid":[165],"bilayer":[166],"assay.":[167],"These":[168],"findings":[169],"confirmed":[170],"is":[173,186],"porin,":[177],"first":[179],"be":[181],"described.":[182],"As":[183],"such,":[184],"it":[185],"potential":[187],"relevance":[188],"pathogenesis":[191],"Lyme":[193],"borreliosis":[194],"physiology":[198],"spirochete.":[201]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}