{"id":"https://openalex.org/W2114843411","doi":"https://doi.org/10.1016/0896-6273(95)90168-x","title":"Constructing the cerebral cortex: Neurogenesis and fate determination","display_name":"Constructing the cerebral cortex: Neurogenesis and fate determination","publication_year":1995,"publication_date":"1995-10-01","ids":{"openalex":"https://openalex.org/W2114843411","doi":"https://doi.org/10.1016/0896-6273(95)90168-x","mag":"2114843411","pmid":"https://pubmed.ncbi.nlm.nih.gov/7576626"},"language":"en","primary_location":{"id":"doi:10.1016/0896-6273(95)90168-x","doi":"https://doi.org/10.1016/0896-6273(95)90168-x","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0896-6273(95)90168-x","pdf_url":"https://doi.org/10.1016/0896-6273(95)90168-x","source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/0896-6273(95)90168-x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045016423","display_name":"Susan K. McConnell","orcid":"https://orcid.org/0000-0003-0668-9569","observed_orcids":["https://orcid.org/0000-0003-0668-9569"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Susan K. McConnell","raw_affiliation_strings":["Department of Biological Sciences, Stanford University, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Stanford University, California 94305, USA","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5045016423"],"corresponding_institution_ids":["https://openalex.org/I97018004"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":{"value":10400,"currency":"USD","value_usd":10400},"fwci":2.6133,"has_fulltext":false,"cited_by_count":422,"citation_normalized_percentile":{"value":0.88888889,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"15","issue":"4","first_page":"761","last_page":"768"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cortical-development","display_name":"cortical development","score":0.9739999771118164},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.925000011920929},{"id":"https://openalex.org/keywords/neuronal-fate-determination","display_name":"neuronal fate determination","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cortical-progenitor-cells","display_name":"cortical progenitor cells","score":0.7620000243186951},{"id":"https://openalex.org/keywords/cell-type-specification","display_name":"cell specification","score":0.699999988079071},{"id":"https://openalex.org/keywords/neuronal-differentiation","display_name":"neuronal differentiation","score":0.5109999775886536},{"id":"https://openalex.org/keywords/neocortex","display_name":"neocortex","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.913090169429779},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7431097030639648},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.6916332244873047},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.5153036117553711},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41520610451698303}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0896-6273(95)90168-x","doi":"https://doi.org/10.1016/0896-6273(95)90168-x","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0896-6273(95)90168-x","pdf_url":"https://doi.org/10.1016/0896-6273(95)90168-x","source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},{"id":"pmid:7576626","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7576626","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/0896-6273(95)90168-x","doi":"https://doi.org/10.1016/0896-6273(95)90168-x","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0896-6273(95)90168-x","pdf_url":"https://doi.org/10.1016/0896-6273(95)90168-x","source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3706698362","display_name":"Determination of neuronal fates in visual cortex","funder_award_id":"R01EY008411","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8665099357","display_name":null,"funder_award_id":"MH51864","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2114843411.pdf"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W142333331","https://openalex.org/W1221824048","https://openalex.org/W1483007837","https://openalex.org/W1514358211","https://openalex.org/W1537081661","https://openalex.org/W1575064426","https://openalex.org/W1616463521","https://openalex.org/W1620986627","https://openalex.org/W1628572451","https://openalex.org/W1773629427","https://openalex.org/W1891830703","https://openalex.org/W1967533792","https://openalex.org/W1969857864","https://openalex.org/W1972067702","https://openalex.org/W1972775580","https://openalex.org/W1973303770","https://openalex.org/W1973385838","https://openalex.org/W1974999120","https://openalex.org/W1979060895","https://openalex.org/W1989163998","https://openalex.org/W1994406909","https://openalex.org/W1996562234","https://openalex.org/W2000745458","https://openalex.org/W2001550066","https://openalex.org/W2003680422","https://openalex.org/W2005598371","https://openalex.org/W2005746771","https://openalex.org/W2007261940","https://openalex.org/W2016503493","https://openalex.org/W2019402991","https://openalex.org/W2021186319","https://openalex.org/W2021515035","https://openalex.org/W2022274052","https://openalex.org/W2023930954","https://openalex.org/W2026904817","https://openalex.org/W2028480293","https://openalex.org/W2033223846","https://openalex.org/W2036442380","https://openalex.org/W2037390777","https://openalex.org/W2037832186","https://openalex.org/W2047493187","https://openalex.org/W2054426244","https://openalex.org/W2055532903","https://openalex.org/W2060645534","https://openalex.org/W2062652610","https://openalex.org/W2067033192","https://openalex.org/W2069421204","https://openalex.org/W2071535176","https://openalex.org/W2077167737","https://openalex.org/W2077576885","https://openalex.org/W2077630079","https://openalex.org/W2078305716","https://openalex.org/W2081028995","https://openalex.org/W2084577485","https://openalex.org/W2092894479","https://openalex.org/W2093712120","https://openalex.org/W2102409931","https://openalex.org/W2108034643","https://openalex.org/W2108325176","https://openalex.org/W2116360511","https://openalex.org/W2124348595","https://openalex.org/W2124982235","https://openalex.org/W2130793535","https://openalex.org/W2135191640","https://openalex.org/W2142003657","https://openalex.org/W2143970121","https://openalex.org/W2150232640","https://openalex.org/W2161196618","https://openalex.org/W2164474108","https://openalex.org/W2227656635","https://openalex.org/W2311335737","https://openalex.org/W4210958860","https://openalex.org/W4241595688","https://openalex.org/W4285719527","https://openalex.org/W7061377211"],"related_works":["https://openalex.org/W1675085568","https://openalex.org/W1986651814","https://openalex.org/W7051961922","https://openalex.org/W3115464675","https://openalex.org/W2754685558","https://openalex.org/W3093899911","https://openalex.org/W2056885206","https://openalex.org/W2792369947","https://openalex.org/W1521225570","https://openalex.org/W2947615095"],"abstract_inverted_index":{"Sitting":[0],"at":[1],"the":[2,8,12,15,21,27,43,49,69,100,120,123,133,139],"apex":[3],"of":[4,18,45,51,59,87,102,122,136,150],"neural":[5],"processing":[6],"in":[7,68,74,91,113,130],"mammalian":[9],"brain":[10,71],"is":[11],"cerebral":[13,23,124],"cortex,":[14,125],"convoluted":[16],"sheet":[17],"neurons":[19,67],"covering":[20],"two":[22],"hemispheres.":[24],"Neurons":[25],"within":[26],"neocortex":[28],"underlie":[29],"our":[30],"most":[31],"sophisticated":[32],"cognitive":[33],"and":[34,37,57,77,117,145,153],"perceptual":[35],"abilities":[36],"are":[38,72,107],"thus":[39],"highly":[40,75],"specialized":[41],"for":[42],"analysis":[44],"sensory":[46],"inputs":[47],"or":[48],"generation":[50],"motor":[52],"outputs.":[53],"The":[54],"position,":[55],"connectivity,":[56],"morphology":[58],"each":[60],"neuron":[61],"reflect":[62],"its":[63],"particular":[64],"function.":[65],"Although":[66],"adult":[70],"organized":[73],"ordered":[76],"differentiated":[78],"arrays,":[79],"these":[80],"cells":[81,86,93],"arise":[82],"from":[83,109],"dividing":[84],"progenitor":[85],"a":[88,143],"simple":[89],"neuroepithelium":[90],"which":[92],"appear":[94],"morphologically":[95],"indistinguishable.":[96],"This":[97],"review":[98],"addresses":[99],"question":[101],"how":[103],"diverse":[104],"neuronal":[105],"phenotypes":[106],"generated":[108],"apparently":[110],"homogeneous":[111],"progenitors":[112],"appropriate":[114],"numbers,":[115],"times,":[116],"positions":[118],"during":[119],"development":[121],"focusing":[126],"on":[127],"key":[128],"steps":[129],"neurogenesis":[131],"including":[132],"molecular":[134],"control":[135],"cell":[137,146],"number,":[138],"decision":[140],"to":[141],"generate":[142],"neuron,":[144],"type":[147],"specification.":[148],"Overview":[149],"Cortical":[151],"Organization":[152],"Development":[154]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}