{"id":"https://openalex.org/W2114798009","doi":"https://doi.org/10.1111/j.1439-0507.2009.01785.x","title":"Incidence and predictors of invasive candidiasis associated with candidaemia in children","display_name":"Incidence and predictors of invasive candidiasis associated with candidaemia in children","publication_year":2009,"publication_date":"2009-10-12","ids":{"openalex":"https://openalex.org/W2114798009","doi":"https://doi.org/10.1111/j.1439-0507.2009.01785.x","mag":"2114798009","pmid":"https://pubmed.ncbi.nlm.nih.gov/19821906","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2888996"},"language":"en","primary_location":{"id":"doi:10.1111/j.1439-0507.2009.01785.x","doi":"https://doi.org/10.1111/j.1439-0507.2009.01785.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1439-0507.2009.01785.x","pdf_url":null,"source":{"id":"https://openalex.org/S80731565","display_name":"Mycoses","issn_l":"0027-5557","issn":["0027-5557","0933-7407","1439-0507"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mycoses","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2888996","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022029315","display_name":"Ara Festekjian","orcid":"https://orcid.org/0000-0002-8244-4785","observed_orcids":["https://orcid.org/0000-0002-8244-4785"]},"institutions":[{"id":"https://openalex.org/I1336910626","display_name":"Children's Hospital Los Angeles","ror":"https://ror.org/00412ts95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336910626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ara Festekjian","raw_affiliation_strings":["Childrens Hospital Los Angeles, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Childrens Hospital Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1336910626"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026635936","display_name":"Michael Noel Neely","orcid":"https://orcid.org/0000-0002-1675-8276","observed_orcids":["https://orcid.org/0000-0002-1675-8276"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1336910626","display_name":"Children's Hospital Los Angeles","ror":"https://ror.org/00412ts95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336910626"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael Neely","raw_affiliation_strings":["Childrens Hospital Los Angeles, Los Angeles, CA, USA","Department of Paediatrics, University of Southern California School of Medicine, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Childrens Hospital Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1336910626"]},{"raw_affiliation_string":"Department of Paediatrics, University of Southern California School of Medicine, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5026635936"],"corresponding_institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1336910626"],"apc_list":{"value":4780,"currency":"USD","value_usd":4780},"apc_paid":null,"fwci":0.6868,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.73923521,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"54","issue":"2","first_page":"146","last_page":"153"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/invasive-candidiasis","display_name":"invasive candidiasis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/candidemia","display_name":"candidemia","score":0.996999979019165},{"id":"https://openalex.org/keywords/pediatric-candidiasis","display_name":"pediatric candidiasis","score":0.7829999923706055},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9929999709129333},{"id":"https://openalex.org/keywords/preterm-birth","display_name":"preterm birth","score":0.8270000219345093},{"id":"https://openalex.org/keywords/echocardiography","display_name":"echocardiography","score":0.7850000262260437},{"id":"https://openalex.org/keywords/ophthalmological-examination","display_name":"ophthalmological examination","score":0.7789999842643738},{"id":"https://openalex.org/keywords/immunocompetent-children","display_name":"immunocompetent child","score":0.781000018119812}],"concepts":[{"id":"https://openalex.org/C2780161414","wikidata":"https://www.wikidata.org/wiki/Q29887808","display_name":"Invasive candidiasis","level":4,"score":0.8365223407745361},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.8232726454734802},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6195319890975952},{"id":"https://openalex.org/C2910751997","wikidata":"https://www.wikidata.org/wiki/Q3718510","display_name":"Echinocandins","level":5,"score":0.4246976375579834},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.38146573305130005},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3744019567966461},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.33112671971321106},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.21069765090942383},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.15908706188201904},{"id":"https://openalex.org/C2780402444","wikidata":"https://www.wikidata.org/wiki/Q420875","display_name":"Caspofungin","level":4,"score":0.08030182123184204},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058365","descriptor_name":"Candidiasis, Invasive","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D058365","descriptor_name":"Candidiasis, Invasive","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D058365","descriptor_name":"Candidiasis, Invasive","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D058365","descriptor_name":"Candidiasis, Invasive","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D058387","descriptor_name":"Candidemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D058387","descriptor_name":"Candidemia","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D058387","descriptor_name":"Candidemia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1439-0507.2009.01785.x","doi":"https://doi.org/10.1111/j.1439-0507.2009.01785.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1439-0507.2009.01785.x","pdf_url":null,"source":{"id":"https://openalex.org/S80731565","display_name":"Mycoses","issn_l":"0027-5557","issn":["0027-5557","0933-7407","1439-0507"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mycoses","raw_type":"journal-article"},{"id":"pmid:19821906","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19821906","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mycoses","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2295646","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2888996","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2888996","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2888996","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mycoses","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2295646","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2888996","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4666417109","display_name":"Plasma and Genital HIV Dynamics in Women","funder_award_id":"K23AI076106","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W71980121","https://openalex.org/W1968237425","https://openalex.org/W1975755498","https://openalex.org/W1985021288","https://openalex.org/W1995287041","https://openalex.org/W2008519120","https://openalex.org/W2013907403","https://openalex.org/W2024212069","https://openalex.org/W2030502203","https://openalex.org/W2034661822","https://openalex.org/W2035720516","https://openalex.org/W2047682827","https://openalex.org/W2058932690","https://openalex.org/W2060628325","https://openalex.org/W2071176269","https://openalex.org/W2072464950","https://openalex.org/W2073522841","https://openalex.org/W2076689151","https://openalex.org/W2097510500","https://openalex.org/W2111240123","https://openalex.org/W2116068468","https://openalex.org/W2126140175","https://openalex.org/W2133328722","https://openalex.org/W2138620668","https://openalex.org/W2143443625","https://openalex.org/W2146558016","https://openalex.org/W2150428940","https://openalex.org/W2157766752","https://openalex.org/W2162221318","https://openalex.org/W2166734004","https://openalex.org/W2171155970","https://openalex.org/W2418799496","https://openalex.org/W4240057336"],"related_works":["https://openalex.org/W2064307150","https://openalex.org/W4416659879","https://openalex.org/W2985313597","https://openalex.org/W7121562878","https://openalex.org/W4389665318","https://openalex.org/W4389030939","https://openalex.org/W3189565226","https://openalex.org/W1834964532","https://openalex.org/W2752181127","https://openalex.org/W4361216064"],"abstract_inverted_index":{"Risk":[0],"factors":[1,50],"for":[2,51,72,185],"invasive":[3,52,73,108,141,186],"candidiasis":[4,33,53,74,109,187],"in":[5,61,149,157,188],"children":[6,20,165,190],"with":[7,21,107,140],"candidaemia":[8,22,60,133,153],"are":[9],"poorly":[10],"defined.":[11],"We":[12],"performed":[13],"a":[14],"retrospective":[15],"cohort":[16],"study":[17],"of":[18,38,48,59,76,132,152],"all":[19],"at":[23,167],"our":[24,158,173],"tertiary":[25],"children's":[26],"hospital":[27],"from":[28],"2000":[29],"to":[30],"2006.":[31],"Invasive":[32,143],"was":[34,154],"diagnosed":[35],"by":[36,179],"review":[37],"the":[39,62,100,150],"medical":[40],"record":[41],"and":[42,90,129,163,177],"standardised":[43],"EORTC/MSG":[44],"criteria.":[45],"A":[46],"variety":[47],"risk":[49],"were":[54,69,105,137,166,182],"explored.":[55],"Of":[56,99],"194":[57],"episodes":[58],"microbiology":[63],"laboratory":[64],"database,":[65],"180":[66,101],"clinical":[67],"records":[68],"available.":[70],"Evaluation":[71],"consisted":[75],"174":[77],"(97%)":[78],"echocardiograms,":[79],"167":[80],"(93%)":[81],"dilated":[82],"ophthalmological":[83],"examinations,":[84],"136":[85],"(76%)":[86],"chest":[87],"CT":[88],"scans":[89],"108":[91],"(60%)":[92],"abdominal":[93],"ultrasounds":[94],"(complete,":[95],"hepatosplenic":[96],"or":[97,147],"renal).":[98],"patients,":[102],"15":[103],"(8%)":[104],"identified":[106],"(4":[110],"proven,":[111],"1":[112],"probable,":[113,148],"10":[114],"possible).":[115],"Prematurity":[116],"<32":[117],"weeks":[118],"(P":[119,126,134],"<":[120,127],"0.01),":[121,128],"an":[122,180],"underlying":[123],"immunocompromising":[124],"disorder":[125],"\u22652":[130],"days":[131],"=":[135],"0.05)":[136],"significantly":[138,168],"associated":[139],"candidiasis.":[142],"candidiasis,":[144],"especially":[145],"proven":[146],"setting":[151],"not":[155],"common":[156],"hospital,":[159],"but":[160],"premature":[161],"infants":[162],"immunocompromised":[164],"higher":[169],"risk.":[170],"Based":[171],"on":[172],"findings,":[174],"extensive":[175],"imaging":[176],"examination":[178],"ophthalmologist":[181],"particularly":[183],"low-yield":[184],"immunocompetent":[189],"beyond":[191],"infancy.":[192]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}