{"id":"https://openalex.org/W2114726424","doi":"https://doi.org/10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","title":"Antioxidant activity of Nigella sativa essential oil","display_name":"Antioxidant activity of Nigella sativa essential oil","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W2114726424","doi":"https://doi.org/10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","mag":"2114726424","pmid":"https://pubmed.ncbi.nlm.nih.gov/10925395"},"language":"en","primary_location":{"id":"doi:10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","doi":"https://doi.org/10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","is_oa":false,"landing_page_url":"https://doi.org/10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","pdf_url":null,"source":{"id":"https://openalex.org/S206789554","display_name":"Phytotherapy Research","issn_l":"0951-418X","issn":["0951-418X","1099-1573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytotherapy Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053560862","display_name":"M. Burits","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"M. Burits","raw_affiliation_strings":["Institute of Pharmacognosy, Karl-Franzens-University of Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmacognosy, Karl-Franzens-University of Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012672741","display_name":"Franz Bu\u010dar","orcid":"https://orcid.org/0000-0002-7417-616X","observed_orcids":["https://orcid.org/0000-0002-7417-616X"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"F. Bucar","raw_affiliation_strings":["Institute of Pharmacognosy, Karl-Franzens-University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmacognosy, Karl-Franzens-University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5012672741"],"corresponding_institution_ids":["https://openalex.org/I15766117"],"apc_list":{"value":4880,"currency":"USD","value_usd":4880},"apc_paid":null,"fwci":23.4876,"has_fulltext":false,"cited_by_count":1862,"citation_normalized_percentile":{"value":0.99303603,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"14","issue":"5","first_page":"323","last_page":"328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12750","display_name":"Nigella sativa pharmacological applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12750","display_name":"Nigella sativa pharmacological applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nigella-sativa","display_name":"Nigella sativa","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/thymoquinone","display_name":"thymoquinone","score":0.9940000176429749},{"id":"https://openalex.org/keywords/carvacrol","display_name":"carvacrol","score":0.9959999918937683},{"id":"https://openalex.org/keywords/anethole","display_name":"anethole","score":0.8930000066757202},{"id":"https://openalex.org/keywords/terpinen-4-ol","display_name":"terpinen-4-ol","score":0.9890000224113464},{"id":"https://openalex.org/keywords/free-radical-scavenging-activity","display_name":"free radical scavenging","score":0.9459999799728394},{"id":"https://openalex.org/keywords/lipid-peroxidation-inhibition","display_name":"lipid peroxidation inhibition","score":0.8510000109672546},{"id":"https://openalex.org/keywords/deoxyribose-degradation","display_name":"deoxyribose degradation","score":0.9070000052452087},{"id":"https://openalex.org/keywords/volatile-compound-composition","display_name":"volatile compound composition","score":0.6840000152587891}],"concepts":[{"id":"https://openalex.org/C2993714443","wikidata":"https://www.wikidata.org/wiki/Q160575","display_name":"Nigella sativa","level":2,"score":0.936208963394165},{"id":"https://openalex.org/C2779034068","wikidata":"https://www.wikidata.org/wiki/Q7799650","display_name":"Thymoquinone","level":3,"score":0.9106349945068359},{"id":"https://openalex.org/C2780676017","wikidata":"https://www.wikidata.org/wiki/Q225543","display_name":"Carvacrol","level":3,"score":0.8299580216407776},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7476159334182739},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6753900051116943},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.6188569068908691},{"id":"https://openalex.org/C2777709666","wikidata":"https://www.wikidata.org/wiki/Q192454","display_name":"Deoxyribose","level":3,"score":0.5628923177719116},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5593565702438354},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.5421894192695618},{"id":"https://openalex.org/C2778796168","wikidata":"https://www.wikidata.org/wiki/Q27105777","display_name":"Anethole","level":3,"score":0.5397364497184753},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.44564640522003174},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3515501916408539},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2833508849143982},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10030382871627808},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001713","descriptor_name":"Biphenyl Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003855","descriptor_name":"Deoxyribose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005290","descriptor_name":"Ferric Compounds","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007202","descriptor_name":"Indicators and Reagents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008401","descriptor_name":"Gas Chromatography-Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010851","descriptor_name":"Picrates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010938","descriptor_name":"Plant Oils","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010938","descriptor_name":"Plant Oils","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012639","descriptor_name":"Seeds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015764","descriptor_name":"Bepridil","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D015764","descriptor_name":"Bepridil","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019661","descriptor_name":"Apiaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","doi":"https://doi.org/10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","is_oa":false,"landing_page_url":"https://doi.org/10.1002/1099-1573(200008)14:5<323::aid-ptr621>3.0.co;2-q","pdf_url":null,"source":{"id":"https://openalex.org/S206789554","display_name":"Phytotherapy Research","issn_l":"0951-418X","issn":["0951-418X","1099-1573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytotherapy Research","raw_type":"journal-article"},{"id":"pmid:10925395","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10925395","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytotherapy research : PTR","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W76480438","https://openalex.org/W125730286","https://openalex.org/W189298505","https://openalex.org/W238391856","https://openalex.org/W277764201","https://openalex.org/W623901733","https://openalex.org/W1543197883","https://openalex.org/W1621522410","https://openalex.org/W1817019644","https://openalex.org/W1820599226","https://openalex.org/W1966282630","https://openalex.org/W1969119976","https://openalex.org/W1974548221","https://openalex.org/W1976915221","https://openalex.org/W1988587584","https://openalex.org/W2002372821","https://openalex.org/W2022739607","https://openalex.org/W2022833615","https://openalex.org/W2024716555","https://openalex.org/W2035894729","https://openalex.org/W2041293207","https://openalex.org/W2050710327","https://openalex.org/W2051833062","https://openalex.org/W2076156821","https://openalex.org/W2099865227","https://openalex.org/W2113523531","https://openalex.org/W2202554561","https://openalex.org/W2321531146","https://openalex.org/W2405887519","https://openalex.org/W3200228556","https://openalex.org/W4245936121","https://openalex.org/W4388150938"],"related_works":["https://openalex.org/W2089443158","https://openalex.org/W2041802157","https://openalex.org/W2479330534","https://openalex.org/W2032792967","https://openalex.org/W1990088140","https://openalex.org/W2015235051","https://openalex.org/W1520854112","https://openalex.org/W7217590357","https://openalex.org/W2066205805","https://openalex.org/W4415928992"],"abstract_inverted_index":{"The":[0],"essential":[1,47,92],"oil":[2,48,93,108],"of":[3,90,99,114],"black":[4],"cumin":[5],"seeds,":[6],"Nigella":[7,100],"sativa":[8,101],"L.,":[9],"was":[10,118],"tested":[11,54],"for":[12,20,59,77],"a":[13,105],"possible":[14],"antioxidant":[15,51],"activity.":[16,66],"A":[17],"rapid":[18],"evaluation":[19],"antioxidants,":[21],"using":[22],"two":[23],"TLC":[24],"screening":[25],"methods,":[26],"showed":[27,109],"that":[28,110],"thymoquinone":[29],"and":[30,35,45,83,103],"the":[31,46,56,75,84,91,111,115,126],"components":[32],"carvacrol,":[33],"t-anethole":[34],"4-terpineol":[36],"demonstrated":[37],"respectable":[38],"radical":[39,71],"scavenging":[40,72],"property.":[41],"These":[42],"four":[43],"constituents":[44],"possessed":[49],"variable":[50],"activity":[52],"when":[53],"in":[55,74,81],"diphenylpicrylhydracyl":[57],"assay":[58,76],"non-specific":[60],"hydrogen":[61],"atom":[62],"or":[63],"electron":[64],"donating":[65],"They":[67],"were":[68,122],"also":[69],"effective.OH":[70],"agents":[73],"non-enzymatic":[78],"lipid":[79],"peroxidation":[80],"liposomes":[82],"deoxyribose":[85],"degradation":[86],"assay.":[87],"GC-MS":[88],"analysis":[89],"obtained":[94],"from":[95,104],"six":[96],"different":[97],"samples":[98],"seeds":[102],"commercial":[106],"fixed":[107],"qualitative":[112],"composition":[113],"volatile":[116],"compounds":[117],"almost":[119],"identical.":[120],"Differences":[121],"mainly":[123],"restricted":[124],"to":[125],"quantitative":[127],"composition.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":40},{"year":2025,"cited_by_count":38},{"year":2024,"cited_by_count":64},{"year":2023,"cited_by_count":75},{"year":2022,"cited_by_count":104},{"year":2021,"cited_by_count":91},{"year":2020,"cited_by_count":125},{"year":2019,"cited_by_count":97},{"year":2018,"cited_by_count":107},{"year":2017,"cited_by_count":95},{"year":2016,"cited_by_count":113},{"year":2015,"cited_by_count":120},{"year":2014,"cited_by_count":137},{"year":2013,"cited_by_count":110},{"year":2012,"cited_by_count":92}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}