{"id":"https://openalex.org/W2114609358","doi":"https://doi.org/10.1016/j.fsigen.2009.02.010","title":"An integrated microfluidic device for DNA purification and PCR amplification of STR fragments","display_name":"An integrated microfluidic device for DNA purification and PCR amplification of STR fragments","publication_year":2009,"publication_date":"2009-10-08","ids":{"openalex":"https://openalex.org/W2114609358","doi":"https://doi.org/10.1016/j.fsigen.2009.02.010","mag":"2114609358","pmid":"https://pubmed.ncbi.nlm.nih.gov/20215029"},"language":"en","primary_location":{"id":"doi:10.1016/j.fsigen.2009.02.010","doi":"https://doi.org/10.1016/j.fsigen.2009.02.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fsigen.2009.02.010","pdf_url":null,"source":{"id":"https://openalex.org/S18992820","display_name":"Forensic Science International Genetics","issn_l":"1872-4973","issn":["1872-4973","1878-0326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Forensic Science International: Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065971997","display_name":"Joan M. Bienvenue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joan M. Bienvenue","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, VA 22904, USA. joan.bienvenue@lmco.com","Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, VA 22904, USA. joan.bienvenue@lmco.com","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064729543","display_name":"Lindsay A. Legendre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lindsay A. Legendre","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046014884","display_name":"Jerome P. Ferrance","orcid":"https://orcid.org/0000-0003-1020-8289","observed_orcids":["https://orcid.org/0000-0003-1020-8289"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerome P. Ferrance","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031563436","display_name":"James P. Landers","orcid":"https://orcid.org/0000-0002-9310-1796","observed_orcids":["https://orcid.org/0000-0002-9310-1796"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James P. Landers","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States","Department of Engineering, University of Virginia, Charlottesville, VA 22904, United States","Department of Pathology, University of Virginia Health Science Center, Charlottesville, VA 22908, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Engineering, University of Virginia, Charlottesville, VA 22904, United States","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Pathology, University of Virginia Health Science Center, Charlottesville, VA 22908, United States","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5065971997"],"corresponding_institution_ids":["https://openalex.org/I51556381"],"apc_list":{"value":5020,"currency":"USD","value_usd":5020},"apc_paid":null,"fwci":7.2094,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.97675299,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"4","issue":"3","first_page":"178","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silica-solid-phase-extraction","display_name":"silica solid-phase extraction","score":0.7490000128746033},{"id":"https://openalex.org/keywords/on-chip-pcr","display_name":"on-chip PCR","score":0.8130000233650208},{"id":"https://openalex.org/keywords/glass-microchannels","display_name":"glass microchannels","score":0.7110000252723694},{"id":"https://openalex.org/keywords/forensic-genetics","display_name":"forensic genetics","score":0.7369999885559082},{"id":"https://openalex.org/keywords/multiplex-pcr","display_name":"multiplex PCR","score":0.7139999866485596},{"id":"https://openalex.org/keywords/dna-purification","display_name":"DNA purification","score":0.3499999940395355}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.7505307793617249},{"id":"https://openalex.org/C8185291","wikidata":"https://www.wikidata.org/wiki/Q2844457","display_name":"Amplicon","level":4,"score":0.7311838269233704},{"id":"https://openalex.org/C63662833","wikidata":"https://www.wikidata.org/wiki/Q6839341","display_name":"Microchannel","level":2,"score":0.616731584072113},{"id":"https://openalex.org/C78063203","wikidata":"https://www.wikidata.org/wiki/Q3062596","display_name":"DNA extraction","level":4,"score":0.5950137376785278},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5048165917396545},{"id":"https://openalex.org/C50712719","wikidata":"https://www.wikidata.org/wiki/Q446473","display_name":"Syringe driver","level":3,"score":0.45711469650268555},{"id":"https://openalex.org/C73826308","wikidata":"https://www.wikidata.org/wiki/Q684907","display_name":"Elution","level":2,"score":0.45130643248558044},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.43421411514282227},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4279305636882782},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.3673064112663269},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.26165637373924255},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.25026679039001465},{"id":"https://openalex.org/C2778571141","wikidata":"https://www.wikidata.org/wiki/Q273318","display_name":"Syringe","level":2,"score":0.18121451139450073},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0777658224105835},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012661","descriptor_name":"Semen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012822","descriptor_name":"Silicon Dioxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019075","descriptor_name":"Electrophoresis, Capillary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020080","descriptor_name":"Tandem Repeat Sequences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.fsigen.2009.02.010","doi":"https://doi.org/10.1016/j.fsigen.2009.02.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fsigen.2009.02.010","pdf_url":null,"source":{"id":"https://openalex.org/S18992820","display_name":"Forensic Science International Genetics","issn_l":"1872-4973","issn":["1872-4973","1878-0326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Forensic Science International: Genetics","raw_type":"journal-article"},{"id":"pmid:20215029","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20215029","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Forensic science international. Genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W71010687","https://openalex.org/W146644175","https://openalex.org/W1875906722","https://openalex.org/W1968206248","https://openalex.org/W1968336943","https://openalex.org/W1975763728","https://openalex.org/W1981466266","https://openalex.org/W1986593058","https://openalex.org/W1987921431","https://openalex.org/W1989360051","https://openalex.org/W1999323319","https://openalex.org/W2000683678","https://openalex.org/W2002213641","https://openalex.org/W2006856300","https://openalex.org/W2007762328","https://openalex.org/W2010062884","https://openalex.org/W2015570829","https://openalex.org/W2021161855","https://openalex.org/W2034758188","https://openalex.org/W2052383391","https://openalex.org/W2060246168","https://openalex.org/W2063064357","https://openalex.org/W2063250806","https://openalex.org/W2065469879","https://openalex.org/W2070378283","https://openalex.org/W2079112687","https://openalex.org/W2082692130","https://openalex.org/W2086335675","https://openalex.org/W2086896805","https://openalex.org/W2090983970","https://openalex.org/W2094010576","https://openalex.org/W2094691790","https://openalex.org/W2118830656","https://openalex.org/W2120994472","https://openalex.org/W2124211014","https://openalex.org/W2128691519","https://openalex.org/W2133988692","https://openalex.org/W2141591837","https://openalex.org/W2148927531","https://openalex.org/W2158905512","https://openalex.org/W2168611191"],"related_works":["https://openalex.org/W2065279947","https://openalex.org/W823381703","https://openalex.org/W2186339631","https://openalex.org/W2124826926","https://openalex.org/W1999866497","https://openalex.org/W2104288017","https://openalex.org/W2613019099","https://openalex.org/W2168499180","https://openalex.org/W2094010576","https://openalex.org/W2521028815"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}