{"id":"https://openalex.org/W2114503271","doi":"https://doi.org/10.1016/j.vhri.2013.01.012","title":"The Health Economic Impact of Universal Infant Vaccination with the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine as Compared with 13-Valent Pneumococcal Conjugate Vaccine in Hong Kong","display_name":"The Health Economic Impact of Universal Infant Vaccination with the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine as Compared with 13-Valent Pneumococcal Conjugate Vaccine in Hong Kong","publication_year":2013,"publication_date":"2013-03-23","ids":{"openalex":"https://openalex.org/W2114503271","doi":"https://doi.org/10.1016/j.vhri.2013.01.012","mag":"2114503271","pmid":"https://pubmed.ncbi.nlm.nih.gov/29702855"},"language":"en","primary_location":{"id":"doi:10.1016/j.vhri.2013.01.012","doi":"https://doi.org/10.1016/j.vhri.2013.01.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vhri.2013.01.012","pdf_url":"http://www.valuehealthregionalissues.com/article/S2212109913000137/pdf","source":{"id":"https://openalex.org/S2764833115","display_name":"Value in Health Regional Issues","issn_l":"2212-1099","issn":["2212-1099","2212-1102"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health Regional Issues","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.valuehealthregionalissues.com/article/S2212109913000137/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101631635","display_name":"Kenneth K.C. Lee","orcid":"https://orcid.org/0000-0002-2583-0030","observed_orcids":["https://orcid.org/0000-0002-2583-0030"]},"institutions":[{"id":"https://openalex.org/I11662577","display_name":"Monash University Malaysia","ror":"https://ror.org/00yncr324","country_code":"MY","type":"education","lineage":["https://openalex.org/I11662577","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","MY"],"is_corresponding":true,"raw_author_name":"Kenneth K.C. Lee","raw_affiliation_strings":["Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus, Selangor, Malaysia. Electronic address: lee@monash.edu","Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus, Selangor, Malaysia. Electronic address: lee@monash.edu","institution_ids":["https://openalex.org/I11662577","https://openalex.org/I56590836"]},{"raw_affiliation_string":"Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus Selangor, Malaysia","institution_ids":["https://openalex.org/I11662577","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111906329","display_name":"David Bin Chia Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I11662577","display_name":"Monash University Malaysia","ror":"https://ror.org/00yncr324","country_code":"MY","type":"education","lineage":["https://openalex.org/I11662577","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","MY"],"is_corresponding":false,"raw_author_name":"David Bin Chia Wu","raw_affiliation_strings":["Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus, Selangor, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus, Selangor, Malaysia","institution_ids":["https://openalex.org/I11662577","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069170824","display_name":"Oleksandr Topachevskyi","orcid":"https://orcid.org/0000-0003-4723-9521","observed_orcids":["https://orcid.org/0000-0003-4723-9521"]},"institutions":[{"id":"https://openalex.org/I4210095529","display_name":"GlaxoSmithKline (Belgium)","ror":"https://ror.org/00n3pea85","country_code":"BE","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210095529"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Oleksandr Topachevskyi","raw_affiliation_strings":["GlaxoSmithKline Vaccines, Wavre, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Vaccines, Wavre, Belgium","institution_ids":["https://openalex.org/I4210095529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006020132","display_name":"Emmanuelle Delgleize","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095529","display_name":"GlaxoSmithKline (Belgium)","ror":"https://ror.org/00n3pea85","country_code":"BE","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210095529"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Emmanuelle Delgleize","raw_affiliation_strings":["GlaxoSmithKline Vaccines, Wavre, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Vaccines, Wavre, Belgium","institution_ids":["https://openalex.org/I4210095529"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058702565","display_name":"Rodrigo DeAntonio","orcid":"https://orcid.org/0000-0003-2586-4115","observed_orcids":["https://orcid.org/0000-0003-2586-4115"]},"institutions":[{"id":"https://openalex.org/I4210095529","display_name":"GlaxoSmithKline (Belgium)","ror":"https://ror.org/00n3pea85","country_code":"BE","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210095529"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Rodrigo DeAntonio","raw_affiliation_strings":["GlaxoSmithKline Vaccines, Wavre, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Vaccines, Wavre, Belgium","institution_ids":["https://openalex.org/I4210095529"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101631635"],"corresponding_institution_ids":["https://openalex.org/I11662577","https://openalex.org/I56590836"],"apc_list":{"value":2400,"currency":"USD","value_usd":2400},"apc_paid":{"value":2400,"currency":"USD","value_usd":2400},"fwci":0.8851,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.74359748,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"2","issue":"1","first_page":"64","last_page":"74"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pneumococcal-conjugate-vaccine","display_name":"pneumococcal conjugate vaccine","score":0.9039999842643738},{"id":"https://openalex.org/keywords/pcv10","display_name":"PCV10","score":0.9879999756813049},{"id":"https://openalex.org/keywords/pcv13","display_name":"PCV13","score":0.9980000257492065},{"id":"https://openalex.org/keywords/nontypeable-haemophilus-influenzae","display_name":"nontypeable Haemophilus influenzae","score":0.8360000252723694},{"id":"https://openalex.org/keywords/infant-immunization","display_name":"infant immunization","score":0.8140000104904175},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.8270000219345093},{"id":"https://openalex.org/keywords/invasive-pneumococcal-disease","display_name":"invasive pneumococcal disease","score":0.9229999780654907},{"id":"https://openalex.org/keywords/community-acquired-pneumonia","display_name":"community-acquired pneumonia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/acute-otitis-media","display_name":"acute otitis media","score":0.9919999837875366},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.9589999914169312},{"id":"https://openalex.org/keywords/hong-kong","display_name":"Hong Kong","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8045985102653503},{"id":"https://openalex.org/C2778866548","wikidata":"https://www.wikidata.org/wiki/Q7205991","display_name":"Pneumococcal conjugate vaccine","level":4,"score":0.757026195526123},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.7344602346420288},{"id":"https://openalex.org/C2776925733","wikidata":"https://www.wikidata.org/wiki/Q1141979","display_name":"Haemophilus influenzae","level":3,"score":0.5725041031837463},{"id":"https://openalex.org/C2779583294","wikidata":"https://www.wikidata.org/wiki/Q5161160","display_name":"Conjugate vaccine","level":4,"score":0.5563402771949768},{"id":"https://openalex.org/C2779892413","wikidata":"https://www.wikidata.org/wiki/Q7205992","display_name":"Pneumococcal pneumonia","level":4,"score":0.5455871820449829},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5123482942581177},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4517400562763214},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29412662982940674},{"id":"https://openalex.org/C2781253189","wikidata":"https://www.wikidata.org/wiki/Q221179","display_name":"Streptococcus pneumoniae","level":3,"score":0.282914400100708},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.2618519067764282},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1690112054347992},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.07550054788589478},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.06470608711242676},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05250442028045654},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.vhri.2013.01.012","doi":"https://doi.org/10.1016/j.vhri.2013.01.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vhri.2013.01.012","pdf_url":"http://www.valuehealthregionalissues.com/article/S2212109913000137/pdf","source":{"id":"https://openalex.org/S2764833115","display_name":"Value in Health Regional Issues","issn_l":"2212-1099","issn":["2212-1099","2212-1102"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health Regional Issues","raw_type":"journal-article"},{"id":"pmid:29702855","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29702855","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in health regional issues","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.vhri.2013.01.012","doi":"https://doi.org/10.1016/j.vhri.2013.01.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vhri.2013.01.012","pdf_url":"http://www.valuehealthregionalissues.com/article/S2212109913000137/pdf","source":{"id":"https://openalex.org/S2764833115","display_name":"Value in Health Regional Issues","issn_l":"2212-1099","issn":["2212-1099","2212-1102"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health Regional Issues","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307773","display_name":"GlaxoSmithKline","ror":"https://ror.org/01xsqw823"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2114503271.pdf","grobid_xml":"https://content.openalex.org/works/W2114503271.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W182083651","https://openalex.org/W1561324172","https://openalex.org/W1569826234","https://openalex.org/W1970041510","https://openalex.org/W1984874957","https://openalex.org/W1996665275","https://openalex.org/W2005277733","https://openalex.org/W2013803462","https://openalex.org/W2018077692","https://openalex.org/W2018258661","https://openalex.org/W2018407773","https://openalex.org/W2020149572","https://openalex.org/W2024634994","https://openalex.org/W2030187973","https://openalex.org/W2032436857","https://openalex.org/W2041643249","https://openalex.org/W2045745523","https://openalex.org/W2049386698","https://openalex.org/W2058499293","https://openalex.org/W2058572722","https://openalex.org/W2059608310","https://openalex.org/W2068875006","https://openalex.org/W2075357156","https://openalex.org/W2081550956","https://openalex.org/W2088946688","https://openalex.org/W2092915795","https://openalex.org/W2093536091","https://openalex.org/W2094204413","https://openalex.org/W2101907700","https://openalex.org/W2102952170","https://openalex.org/W2110624979","https://openalex.org/W2122598469","https://openalex.org/W2131244634","https://openalex.org/W2143332828","https://openalex.org/W2150799431","https://openalex.org/W2171323360","https://openalex.org/W2602921578","https://openalex.org/W3025897641","https://openalex.org/W3125148449","https://openalex.org/W4237609757","https://openalex.org/W4250890991","https://openalex.org/W4294316044","https://openalex.org/W6789667486"],"related_works":["https://openalex.org/W2176119732","https://openalex.org/W2797431570","https://openalex.org/W1990186658","https://openalex.org/W2028649541","https://openalex.org/W2086294260","https://openalex.org/W2163286927","https://openalex.org/W1977517171","https://openalex.org/W2557253127","https://openalex.org/W2953723766","https://openalex.org/W2480013577"],"abstract_inverted_index":{"BACKGROUND:":[0],"Pneumococcal":[1],"universal":[2],"vaccination":[3,190,225,250],"in":[4,9,44,56,64,102,246],"Hong":[5,42,103,197,202,247],"Kong":[6,43,104,198,203],"was":[7,71],"introduced":[8],"2009.":[10],"OBJECTIVES:":[11],"We":[12],"assessed":[13],"the":[14,20,33,57,75,106,152,186,241],"health":[15,54,79],"and":[16,78,88,122,126,145,159,181,215,265],"economic":[17,77],"impact":[18,114,150,238],"of":[19,81,154,169,243],"10-valent":[21],"pneumococcal":[22,36,62,83,229,244],"nontypeable":[23,94],"Haemophilus":[24],"influenzae":[25],"protein":[26],"D":[27],"conjugate":[28,37],"vaccine":[29,38],"(PCV-10)":[30],"compared":[31,219,257],"with":[32,109,220,226,258],"current":[34],"13-valent":[35],"(PCV-13)":[39],"recommended":[40],"for":[41,61,98],"2011,":[45],"providing":[46],"new":[47,227],"elements":[48],"to":[49,73,164,175,193,233],"be":[50,252],"considered":[51],"by":[52,133,157],"public":[53],"authorities":[55],"future":[58],"decision-making":[59],"process":[60],"vaccines":[63,230],"this":[65],"country.":[66],"METHODS:":[67],"An":[68],"analytical":[69],"model":[70],"used":[72],"estimate":[74],"annual":[76],"outcomes":[80],"invasive":[82],"disease":[84],"(IPD),":[85],"community-acquired":[86],"pneumonia,":[87],"acute":[89],"otitis":[90],"media":[91],"(AOM),":[92],"including":[93,115],"H.":[95],"influenzae-related":[96],"AOM,":[97],"a":[99,110,235,254],"birth":[100],"cohort":[101],"from":[105],"payer":[107],"perspective":[108],"10-year":[111],"horizon.":[112],"Clinical":[113],"morbidity-mortality,":[116],"quality-adjusted":[117],"life-years":[118],"(QALYs),":[119],"incremental":[120],"costs,":[121],"cost-effectiveness":[123],"comparing":[124],"PCV-10":[125,146,172,189,210,249],"PCV-13":[127,144,161,259],"were":[128,137],"estimated.":[129],"Probabilistic":[130],"sensitivity":[131],"analyses":[132],"using":[134],"alternate":[135],"scenarios":[136],"performed.":[138],"RESULTS:":[139],"Model":[140],"projections":[141],"indicate":[142],"that":[143,209],"have":[147],"approximately":[148],"equivalent":[149],"on":[151,239],"prevention":[153],"deaths":[155],"caused":[156],"IPD":[158],"pneumonia.":[160],"is":[162,173,191,231],"projected":[163,174],"prevent":[165,176],"6":[166],"additional":[167,178,183,237],"cases":[168,180],"IPD,":[170],"whereas":[171],"13,229":[177],"AOM":[179],"101":[182],"QALYs.":[184],"For":[185],"base":[187],"case,":[188],"estimated":[192],"save":[194,216],"44.6":[195],"million":[196,201],"dollars":[199,204],"(34.1":[200],"discounted).":[205],"Sensitivity":[206],"analysis":[207],"indicated":[208],"would":[211,251],"generate":[212,234],"more":[213],"QALYs":[214],"costs":[217],"as":[218],"PCV-13.":[221],"CONCLUSIONS:":[222],"Universal":[223],"infant":[224],"available":[228],"expected":[232],"significant":[236],"reducing":[240],"burden":[242],"diseases":[245],"Kong.":[248],"potentially":[253],"cost-saving":[255],"strategy":[256],"vaccination,":[260],"generating":[261],"better":[262],"cost":[263],"offsets":[264],"higher":[266],"QALY":[267],"gains.":[268]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}