{"id":"https://openalex.org/W2114307403","doi":"https://doi.org/10.1016/0091-6749(81)90049-x","title":"Local heat urticaria/angioedema: Evidence for histamine release without complement activation","display_name":"Local heat urticaria/angioedema: Evidence for histamine release without complement activation","publication_year":1981,"publication_date":"1981-01-01","ids":{"openalex":"https://openalex.org/W2114307403","doi":"https://doi.org/10.1016/0091-6749(81)90049-x","mag":"2114307403","pmid":"https://pubmed.ncbi.nlm.nih.gov/6161144"},"language":"en","primary_location":{"id":"doi:10.1016/0091-6749(81)90049-x","doi":"https://doi.org/10.1016/0091-6749(81)90049-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0091-6749(81)90049-x","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"J.Andrew Grant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.Andrew Grant","raw_affiliation_strings":["From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]},{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083626960","display_name":"Steven R. Findlay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven R. Findlay","raw_affiliation_strings":["From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]},{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077378929","display_name":"David O. Thueson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David O. Thueson","raw_affiliation_strings":["From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]},{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Douglas P. Fine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Douglas P. Fine","raw_affiliation_strings":["From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]},{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111575047","display_name":"Gerald G. Krueger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerald G. Krueger","raw_affiliation_strings":["From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Texas Medical Branch at Galveston Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]},{"raw_affiliation_string":"From the Department of Internal Medicine of the University of Utah Medical Center Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":0.9634,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.75541002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"67","issue":"1","first_page":"75","last_page":"77"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.6675000190734863,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.6675000190734863,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12438","display_name":"Urticaria and Related Conditions","score":0.29350000619888306,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-urticaria","display_name":"heat urticaria","score":0.8790000081062317},{"id":"https://openalex.org/keywords/angioedema","display_name":"angioedema","score":0.9629999995231628},{"id":"https://openalex.org/keywords/histamine-release","display_name":"histamine release","score":0.7940000295639038},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8240000009536743},{"id":"https://openalex.org/keywords/complement-system","display_name":"complement system","score":0.8820000290870667},{"id":"https://openalex.org/keywords/hemolytic-complement-activity","display_name":"hemolytic complement activity","score":0.7269999980926514},{"id":"https://openalex.org/keywords/plasma-histamine","display_name":"plasma histamine","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C1122143","wikidata":"https://www.wikidata.org/wiki/Q61233","display_name":"Histamine","level":2,"score":0.8020713329315186},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.6171613931655884},{"id":"https://openalex.org/C2779121184","wikidata":"https://www.wikidata.org/wiki/Q1166142","display_name":"Erythema","level":2,"score":0.6147940158843994},{"id":"https://openalex.org/C2780966972","wikidata":"https://www.wikidata.org/wiki/Q86","display_name":"Headaches","level":2,"score":0.569066047668457},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.568325936794281},{"id":"https://openalex.org/C2777995640","wikidata":"https://www.wikidata.org/wiki/Q1129007","display_name":"Angioedema","level":2,"score":0.5305431485176086},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.5191358923912048},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5146847367286682},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.4730602502822876},{"id":"https://openalex.org/C2909716297","wikidata":"https://www.wikidata.org/wiki/Q168800","display_name":"Anaphylactoid reactions","level":4,"score":0.4451194107532501},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.4316590428352356},{"id":"https://openalex.org/C2779540182","wikidata":"https://www.wikidata.org/wiki/Q1076345","display_name":"Extravasation","level":2,"score":0.42541033029556274},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4222121834754944},{"id":"https://openalex.org/C2775933838","wikidata":"https://www.wikidata.org/wiki/Q168800","display_name":"Anaphylaxis","level":3,"score":0.4050056040287018},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3972136676311493},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.361797571182251},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3530482351779938},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3197784125804901},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3165817856788635},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19116705656051636},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.1856442391872406}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000799","descriptor_name":"Angioedema","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003167","descriptor_name":"Complement Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006636","descriptor_name":"Histamine Release","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007116","descriptor_name":"Immunization, Passive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011415","descriptor_name":"Complement Factor B","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014581","descriptor_name":"Urticaria","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/0091-6749(81)90049-x","doi":"https://doi.org/10.1016/0091-6749(81)90049-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0091-6749(81)90049-x","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:6161144","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6161144","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of allergy and clinical immunology","raw_type":"Case Reports"},{"id":"mag:2308113072","doi":null,"is_oa":false,"landing_page_url":"https://www.jacionline.org/article/0091-6749(81)90049-X/pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W122867097","https://openalex.org/W184291833","https://openalex.org/W1598475884","https://openalex.org/W1978945299","https://openalex.org/W1984474102","https://openalex.org/W2004114990","https://openalex.org/W2004919440","https://openalex.org/W2012740643","https://openalex.org/W2013550399","https://openalex.org/W2024197571","https://openalex.org/W2034939394","https://openalex.org/W2035686168","https://openalex.org/W2043441836","https://openalex.org/W2043852511","https://openalex.org/W2046956386","https://openalex.org/W2048393869","https://openalex.org/W2048788660","https://openalex.org/W2070898045","https://openalex.org/W2078206019","https://openalex.org/W2079941765","https://openalex.org/W2082345971","https://openalex.org/W2129180014","https://openalex.org/W2132074040","https://openalex.org/W2340805752","https://openalex.org/W2411027317","https://openalex.org/W2416729252","https://openalex.org/W2478765828","https://openalex.org/W2501009526","https://openalex.org/W4234960315","https://openalex.org/W4313313497"],"related_works":["https://openalex.org/W2070754903","https://openalex.org/W2048393869","https://openalex.org/W2023506937","https://openalex.org/W2002764438","https://openalex.org/W2102998149","https://openalex.org/W1987068321","https://openalex.org/W2410025685","https://openalex.org/W2417177565","https://openalex.org/W1987061958","https://openalex.org/W2308113072"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}