{"id":"https://openalex.org/W2114277123","doi":"https://doi.org/10.1152/physiolgenomics.00161.2002","title":"Genome scan for QTLs underlying bone size variation at 10 refined skeletal sites: genetic heterogeneity and the significance of phenotype refinement","display_name":"Genome scan for QTLs underlying bone size variation at 10 refined skeletal sites: genetic heterogeneity and the significance of phenotype refinement","publication_year":2004,"publication_date":"2004-03-29","ids":{"openalex":"https://openalex.org/W2114277123","doi":"https://doi.org/10.1152/physiolgenomics.00161.2002","mag":"2114277123","pmid":"https://pubmed.ncbi.nlm.nih.gov/15039485"},"language":"en","primary_location":{"id":"doi:10.1152/physiolgenomics.00161.2002","doi":"https://doi.org/10.1152/physiolgenomics.00161.2002","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physiolgenomics.00161.2002","pdf_url":null,"source":{"id":"https://openalex.org/S57123121","display_name":"Physiological Genomics","issn_l":"1094-8341","issn":["1094-8341","1531-2267"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Genomics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100844807","display_name":"Qing-Yang Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qing-Yang Huang","raw_affiliation_strings":["Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081448542","display_name":"Fu\u2010Hua Xu","orcid":"https://orcid.org/0000-0002-8318-1825","observed_orcids":["https://orcid.org/0000-0002-8318-1825"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fu-Hua Xu","raw_affiliation_strings":["Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013518217","display_name":"Hui Shen","orcid":"https://orcid.org/0000-0003-0335-6064","observed_orcids":["https://orcid.org/0000-0003-0335-6064","https://orcid.org/0009-0007-1039-8955"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui Shen","raw_affiliation_strings":["Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102131645","display_name":"Hong-Yi Deng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]},{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hong-Yi Deng","raw_affiliation_strings":["Center for Medical Informatics, School of Medicine, Yale University, New Haven, Connecticut 06520-8009","Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, ChangSha, Hunan, 410081, China","Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Informatics, School of Medicine, Yale University, New Haven, Connecticut 06520-8009","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, ChangSha, Hunan, 410081, China","institution_ids":["https://openalex.org/I173759888"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109854642","display_name":"Theresa Conway","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa Conway","raw_affiliation_strings":["Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007234866","display_name":"Yong\u2010Jun Liu","orcid":"https://orcid.org/0000-0002-1728-480X","observed_orcids":["https://orcid.org/0000-0002-1728-480X"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yong-Jun Liu","raw_affiliation_strings":["Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110089593","display_name":"Yao-Zhong Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yao-Zhong Liu","raw_affiliation_strings":["Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454978","display_name":"Jinlong Li","orcid":"https://orcid.org/0000-0002-0915-4095","observed_orcids":["https://orcid.org/0000-0002-0915-4095"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jin-Long Li","raw_affiliation_strings":["Center for Medical Informatics, School of Medicine, Yale University, New Haven, Connecticut 06520-8009"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Informatics, School of Medicine, Yale University, New Haven, Connecticut 06520-8009","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040633212","display_name":"Miaoxin Li","orcid":"https://orcid.org/0000-0002-4733-0109","observed_orcids":["https://orcid.org/0000-0002-4733-0109"]},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Miao-Xin Li","raw_affiliation_strings":["Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, ChangSha, Hunan, 410081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, ChangSha, Hunan, 410081, China","institution_ids":["https://openalex.org/I173759888"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108371659","display_name":"K. Michael Davies","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Michael Davies","raw_affiliation_strings":["Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052478195","display_name":"Robert R. Recker","orcid":"https://orcid.org/0000-0002-8774-1404","observed_orcids":["https://orcid.org/0000-0002-8774-1404"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert R. Recker","raw_affiliation_strings":["Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024194480","display_name":"Hong\u2010Wen Deng","orcid":"https://orcid.org/0000-0002-0387-8818","observed_orcids":["https://orcid.org/0000-0002-0387-8818","https://orcid.org/0000-0003-1933-7095"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]},{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hong-Wen Deng","raw_affiliation_strings":["Center for Medical Informatics, School of Medicine, Yale University, New Haven, Connecticut 06520-8009","Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, ChangSha, Hunan, 410081, China","Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Informatics, School of Medicine, Yale University, New Haven, Connecticut 06520-8009","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, ChangSha, Hunan, 410081, China","institution_ids":["https://openalex.org/I173759888"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, Nebraska 68131","institution_ids":["https://openalex.org/I114493937"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7787,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.84126157,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"17","issue":"3","first_page":"326","last_page":"331"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4763000011444092,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4763000011444092,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.3732999861240387,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.12729999423027039,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quantitative-trait-loci","display_name":"quantitative trait loci","score":0.9470000267028809},{"id":"https://openalex.org/keywords/skeletal-sites","display_name":"skeletal sites","score":0.4970000088214874},{"id":"https://openalex.org/keywords/genetic-heterogeneity","display_name":"genetic heterogeneity","score":0.7749999761581421},{"id":"https://openalex.org/keywords/linkage-analysis","display_name":"linkage analysis","score":0.5649999976158142},{"id":"https://openalex.org/keywords/microsatellite-markers","display_name":"microsatellite markers","score":0.6890000104904175},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.5590000152587891},{"id":"https://openalex.org/keywords/lumbar-spine","display_name":"lumbar spine","score":0.5929999947547913},{"id":"https://openalex.org/keywords/femoral-neck","display_name":"femoral neck","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hip","display_name":"hip","score":0.5989999771118164},{"id":"https://openalex.org/keywords/wrist","display_name":"wrist","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.7791224718093872},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7103614807128906},{"id":"https://openalex.org/C2910560014","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genome Scan","level":5,"score":0.6487128138542175},{"id":"https://openalex.org/C22593422","wikidata":"https://www.wikidata.org/wiki/Q3242583","display_name":"Pedigree chart","level":3,"score":0.586132824420929},{"id":"https://openalex.org/C142870003","wikidata":"https://www.wikidata.org/wiki/Q843863","display_name":"Genetic linkage","level":3,"score":0.5785753726959229},{"id":"https://openalex.org/C61320498","wikidata":"https://www.wikidata.org/wiki/Q265193","display_name":"Microsatellite","level":4,"score":0.5397748351097107},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5108263492584229},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.5100441575050354},{"id":"https://openalex.org/C2775854910","wikidata":"https://www.wikidata.org/wiki/Q4844892","display_name":"Femoral neck","level":3,"score":0.47774118185043335},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.47090983390808105},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.450738787651062},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.36784470081329346},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23766717314720154},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.20412525534629822},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.11203491687774658},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006615","descriptor_name":"Hip","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013131","descriptor_name":"Spine","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014953","descriptor_name":"Wrist","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1152/physiolgenomics.00161.2002","doi":"https://doi.org/10.1152/physiolgenomics.00161.2002","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physiolgenomics.00161.2002","pdf_url":null,"source":{"id":"https://openalex.org/S57123121","display_name":"Physiological Genomics","issn_l":"1094-8341","issn":["1094-8341","1531-2267"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Genomics","raw_type":"journal-article"},{"id":"pmid:15039485","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15039485","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological genomics","raw_type":"Journal Article"},{"id":"pmh:oai:hub.hku.hk:10722/181208","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10722/181208","pdf_url":null,"source":{"id":"https://openalex.org/S4377196271","display_name":"The HKU Scholars Hub (University of Hong Kong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I889458895","host_organization_name":"University of Hong Kong","host_organization_lineage":["https://openalex.org/I889458895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2150513565","display_name":"GENETIC LINKAGE TO LOW PEAK BONE MASS","funder_award_id":"R01AR045349","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2827706692","display_name":null,"funder_award_id":"P01 DC01813-07","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"},{"id":"https://openalex.org/G319540772","display_name":null,"funder_award_id":"R01 GM 60402-01A1","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4191502365","display_name":"GENTICS OF USHER SYNDROME","funder_award_id":"P01DC001813","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"},{"id":"https://openalex.org/G427003618","display_name":null,"funder_award_id":"R01-AR-45349-01","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6064384742","display_name":"CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONS","funder_award_id":"R01GM060402","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G749568872","display_name":"Genetic Basis of Osteoporotic Fractures and Bone Mass","funder_award_id":"K01AR002170","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G956266236","display_name":null,"funder_award_id":"K01 AR02170-01","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320309641","display_name":"Creighton University","ror":"https://ror.org/05wf30g94"},{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W79048465","https://openalex.org/W587813093","https://openalex.org/W1553501519","https://openalex.org/W1695610564","https://openalex.org/W1965265115","https://openalex.org/W1968008611","https://openalex.org/W1969985350","https://openalex.org/W1971265121","https://openalex.org/W1973933542","https://openalex.org/W1975162165","https://openalex.org/W1976353096","https://openalex.org/W1976741643","https://openalex.org/W1980507908","https://openalex.org/W1984303605","https://openalex.org/W1984941837","https://openalex.org/W1985118042","https://openalex.org/W1986817752","https://openalex.org/W1987691142","https://openalex.org/W1995409737","https://openalex.org/W1995849174","https://openalex.org/W2000222427","https://openalex.org/W2000728795","https://openalex.org/W2008178459","https://openalex.org/W2008994943","https://openalex.org/W2010964594","https://openalex.org/W2015703307","https://openalex.org/W2016098246","https://openalex.org/W2017756590","https://openalex.org/W2018625933","https://openalex.org/W2022774763","https://openalex.org/W2025375105","https://openalex.org/W2030364842","https://openalex.org/W2035005844","https://openalex.org/W2039531003","https://openalex.org/W2040156285","https://openalex.org/W2061644594","https://openalex.org/W2064543888","https://openalex.org/W2069751968","https://openalex.org/W2072038834","https://openalex.org/W2072543840","https://openalex.org/W2076440836","https://openalex.org/W2086220616","https://openalex.org/W2087250138","https://openalex.org/W2092395614","https://openalex.org/W2093228844","https://openalex.org/W2110086807","https://openalex.org/W2115335486","https://openalex.org/W2115660903","https://openalex.org/W2133173731","https://openalex.org/W2142198096","https://openalex.org/W2164764737","https://openalex.org/W2168872368","https://openalex.org/W2317806864","https://openalex.org/W2987011813","https://openalex.org/W4237772925"],"related_works":["https://openalex.org/W7096526747","https://openalex.org/W2227909353","https://openalex.org/W2045745211","https://openalex.org/W2121281534","https://openalex.org/W7096709613","https://openalex.org/W2269419870","https://openalex.org/W2074584729","https://openalex.org/W2287817916","https://openalex.org/W2006455563","https://openalex.org/W1997524242"],"abstract_inverted_index":{"To":[0],"identify":[1],"quantitative":[2],"trait":[3],"loci":[4],"(QTLs)":[5],"underlying":[6],"variation":[7],"in":[8,17,126],"bone":[9,78,124],"size,":[10],"we":[11],"conducted":[12],"a":[13],"whole-genome":[14],"linkage":[15,72,103,119],"scan":[16],"53":[18],"pedigrees":[19],"with":[20,99,115],"630":[21],"subjects":[22],"using":[23,87],"380":[24],"microsatellite":[25],"markers.":[26],"Lumbar":[27],"area":[28],"1,":[29],"2,":[30],"3,":[31],"and":[32,47,61,67,70,83,95,111],"4":[33],"at":[34,42,51,80],"the":[35,43,52,88,134],"spine,":[36],"femoral":[37],"neck,":[38],"trochanter,":[39],"intertrochanter":[40],"areas":[41,50],"hip,":[44],"ultradistal,":[45],"mid-distal,":[46],"one-third":[48,108],"distal":[49,109],"wrist":[53],"were":[54,74,97,113],"measured":[55],"by":[56],"dual-energy":[57],"X-ray":[58],"absorptiometry":[59],"(DXA),":[60],"adjusted":[62],"for":[63,76,140],"age,":[64],"height,":[65],"weight,":[66],"sex.":[68],"Two-point":[69],"multipoint":[71],"analyses":[73],"performed":[75],"skeletal":[77,128],"size":[79,125],"each":[81],"site":[82],"their":[84],"composite":[85,141],"measurements":[86,143],"SOLAR":[89],"package.":[90],"Two":[91],"chromosomal":[92],"regions":[93],"(1q22":[94],"10q21)":[96],"identified":[98,114],"significant":[100],"evidence":[101,117],"of":[102,118,137,149],"(LOD":[104,120],">":[105,121],"4.32)":[106],"to":[107,123],"area,":[110],"three":[112],"suggestive":[116],"2.93)":[122],"one":[127],"site.":[129],"Our":[130],"results":[131],"indicated":[132],"that":[133],"low":[135],"power":[136],"QTLs":[138],"mapping":[139],"phenotypic":[142],"may":[144],"result":[145],"from":[146],"genetic":[147],"heterogeneity":[148],"complex":[150],"traits.":[151]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}