{"id":"https://openalex.org/W2113776805","doi":"https://doi.org/10.3109/09540268909089421","title":"Schizophrenia Research: attempting to integrate genetics, neurodevelopment and nosology","display_name":"Schizophrenia Research: attempting to integrate genetics, neurodevelopment and nosology","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W2113776805","doi":"https://doi.org/10.3109/09540268909089421","mag":"2113776805"},"language":"en","primary_location":{"id":"doi:10.3109/09540268909089421","doi":"https://doi.org/10.3109/09540268909089421","is_oa":false,"landing_page_url":"https://doi.org/10.3109/09540268909089421","pdf_url":null,"source":{"id":"https://openalex.org/S136737876","display_name":"International Review of Psychiatry","issn_l":"0954-0261","issn":["0954-0261","1369-1627"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Review of Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5106497970","display_name":"Michael Gill","orcid":"https://orcid.org/0000-0003-0206-5337","observed_orcids":["https://orcid.org/0000-0003-0206-5337","https://orcid.org/0000-0002-9657-1451"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Gill","raw_affiliation_strings":["Genetics Section, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Section, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, United Kingdom","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022302148","display_name":"Caecilia Taylor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Caecilia Taylor","raw_affiliation_strings":["Genetics Section, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Section, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, United Kingdom","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029413844","display_name":"Robin M. Murray","orcid":"https://orcid.org/0000-0003-0829-0519","observed_orcids":["https://orcid.org/0000-0003-0829-0519"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robin M. Murray","raw_affiliation_strings":["Genetics Section, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Section, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, United Kingdom","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7239,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.72459466,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":"4","first_page":"277","last_page":"286"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.8399999737739563},{"id":"https://openalex.org/keywords/genetic-inheritance","display_name":"genetic inheritance","score":0.5270000100135803},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.7080000042915344},{"id":"https://openalex.org/keywords/disease-classification","display_name":"disease classification","score":0.9169999957084656},{"id":"https://openalex.org/keywords/linkage-analysis","display_name":"linkage analysis","score":0.6779999732971191},{"id":"https://openalex.org/keywords/sib-pair-analysis","display_name":"sib-pair analysis","score":0.968999981880188},{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.8830000162124634},{"id":"https://openalex.org/keywords/intrauterine-environment","display_name":"intrauterine environment","score":0.5759999752044678},{"id":"https://openalex.org/keywords/penetrance","display_name":"penetrance","score":0.5910000205039978},{"id":"https://openalex.org/keywords/phenotype-definition","display_name":"phenotype definition","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C72852651","wikidata":"https://www.wikidata.org/wiki/Q845300","display_name":"Nosology","level":2,"score":0.8488345146179199},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.7694814205169678},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5181525945663452},{"id":"https://openalex.org/C84201533","wikidata":"https://www.wikidata.org/wiki/Q7256235","display_name":"Psychiatric genetics","level":3,"score":0.4928272068500519},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4373641908168793},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.42284393310546875},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3524287939071655},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3286660313606262}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3109/09540268909089421","doi":"https://doi.org/10.3109/09540268909089421","is_oa":false,"landing_page_url":"https://doi.org/10.3109/09540268909089421","pdf_url":null,"source":{"id":"https://openalex.org/S136737876","display_name":"International Review of Psychiatry","issn_l":"0954-0261","issn":["0954-0261","1369-1627"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Review of Psychiatry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8999999761581421}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W381461821","https://openalex.org/W648349244","https://openalex.org/W1608407352","https://openalex.org/W1704685837","https://openalex.org/W1801240960","https://openalex.org/W1803375514","https://openalex.org/W1841029273","https://openalex.org/W1963975205","https://openalex.org/W1964007647","https://openalex.org/W1964873353","https://openalex.org/W1966334938","https://openalex.org/W1967721661","https://openalex.org/W1969804484","https://openalex.org/W1974443021","https://openalex.org/W1974608176","https://openalex.org/W1986454580","https://openalex.org/W1997331575","https://openalex.org/W2003488688","https://openalex.org/W2007836835","https://openalex.org/W2013054383","https://openalex.org/W2017881870","https://openalex.org/W2020344898","https://openalex.org/W2030567886","https://openalex.org/W2031603480","https://openalex.org/W2032781839","https://openalex.org/W2039599894","https://openalex.org/W2039903188","https://openalex.org/W2050984100","https://openalex.org/W2051601933","https://openalex.org/W2052770152","https://openalex.org/W2054375526","https://openalex.org/W2065068813","https://openalex.org/W2066103795","https://openalex.org/W2066729833","https://openalex.org/W2067646093","https://openalex.org/W2069855323","https://openalex.org/W2070564733","https://openalex.org/W2076551829","https://openalex.org/W2077561464","https://openalex.org/W2080789361","https://openalex.org/W2083476919","https://openalex.org/W2089142891","https://openalex.org/W2090776561","https://openalex.org/W2091951581","https://openalex.org/W2092123366","https://openalex.org/W2094498855","https://openalex.org/W2094874741","https://openalex.org/W2097649572","https://openalex.org/W2100739993","https://openalex.org/W2100865893","https://openalex.org/W2100976866","https://openalex.org/W2105080473","https://openalex.org/W2118453425","https://openalex.org/W2120909553","https://openalex.org/W2122941998","https://openalex.org/W2128555956","https://openalex.org/W2130630697","https://openalex.org/W2132671292","https://openalex.org/W2140732670","https://openalex.org/W2148477876","https://openalex.org/W2148636100","https://openalex.org/W2151151184","https://openalex.org/W2151836434","https://openalex.org/W2155904872","https://openalex.org/W2156267598","https://openalex.org/W2158303900","https://openalex.org/W2161170629","https://openalex.org/W2164781516","https://openalex.org/W2166431334","https://openalex.org/W2170008072","https://openalex.org/W2286077188","https://openalex.org/W2332142174","https://openalex.org/W2346073133","https://openalex.org/W2401191574","https://openalex.org/W2407561990","https://openalex.org/W2411573330","https://openalex.org/W2461741444","https://openalex.org/W2466597837","https://openalex.org/W2725677243","https://openalex.org/W4210757365","https://openalex.org/W4213356153","https://openalex.org/W4235019056","https://openalex.org/W4244515270","https://openalex.org/W4301382058"],"related_works":["https://openalex.org/W2027732021","https://openalex.org/W1449708584","https://openalex.org/W2006751252","https://openalex.org/W2607403279","https://openalex.org/W2154476429","https://openalex.org/W2476998203","https://openalex.org/W2089114713","https://openalex.org/W2475895080","https://openalex.org/W2112572641","https://openalex.org/W2079761023"],"abstract_inverted_index":{"Recent":[0],"clinical":[1],"and":[2,16,51,73,97,104],"biometrical":[3],"studies":[4,28,106],"strongly":[5],"support":[6],"the":[7,25,36,47,52,57,81,92,95,98,108,115,124,127,141,146],"classical":[8],"findings":[9],"of":[10,49,54,56,80,94,107,110,114,123,126,157],"an":[11],"inherited":[12],"component":[13,129],"in":[14,91,144],"schizophrenia,":[15],"are":[17],"now":[18],"being":[19],"used":[20],"to":[21,23,35,41,132,151],"try":[22],"define":[24],"phenotype.":[26],"Linkage":[27],"have":[29,40],"generated":[30],"conflicting":[31],"data,":[32],"possibly":[33],"due":[34],"necessary":[37],"assumptions":[38],"that":[39],"be":[42],"made":[43],"regarding":[44],"phenotype":[45],"definition,":[46],"model":[48],"inheritance":[50],"degree":[53],"penetrance":[55],"supposed":[58],"gene.":[59],"Alternative":[60],"approaches,":[61],"such":[62],"as":[63],"sib-pair":[64],"analysis":[65],"overcome":[66],"some":[67],"but":[68],"not":[69],"all":[70],"these":[71],"difficulties,":[72],"cytogenetic":[74],"abnormalities":[75],"may":[76],"yet":[77],"outline":[78],"regions":[79],"genome":[82],"for":[83,120],"closer":[84],"scrutiny.":[85],"The":[86],"relationship":[87],"between":[88],"genes":[89],"involved":[90],"development":[93],"brain,":[96],"dysplastic":[99],"features":[100],"suggested":[101],"by":[102],"neuropathologica":[103],"neuroimaging":[105],"brains":[109],"schizophrenics,":[111],"is":[112],"one":[113],"most":[116],"potentially":[117],"productive":[118],"areas":[119],"research.":[121],"Elucidation":[122],"nature":[125],"genetic":[128],"will":[130],"help":[131],"clarify":[133],"whether":[134],"it":[135],"acts":[136],"independently":[137],"or":[138],"synergistically":[139],"with":[140],"foetal":[142],"environment":[143],"producing":[145],"neurodevelopmental":[147],"deviance":[148],"which":[149],"appears":[150],"underlie":[152],"at":[153],"least":[154],"a":[155],"proportion":[156],"schizophrenia.":[158]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}