{"id":"https://openalex.org/W2113677520","doi":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","title":"Biochemical and genetic characterization of the three metabolic routes in Thermococcus kodakarensis linking glyceraldehyde 3\u2010phosphate and 3\u2010phosphoglycerate","display_name":"Biochemical and genetic characterization of the three metabolic routes in Thermococcus kodakarensis linking glyceraldehyde 3\u2010phosphate and 3\u2010phosphoglycerate","publication_year":2011,"publication_date":"2011-07-08","ids":{"openalex":"https://openalex.org/W2113677520","doi":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","mag":"2113677520","pmid":"https://pubmed.ncbi.nlm.nih.gov/21736643"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2958.2011.07762.x","doi":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2011.07762.x","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2011.07762.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062515425","display_name":"Kohei Matsubara","orcid":"https://orcid.org/0000-0002-2734-7595","observed_orcids":["https://orcid.org/0000-0002-2734-7595"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kohei Matsubara","raw_affiliation_strings":["Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040950344","display_name":"Yuusuke Yokooji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuusuke Yokooji","raw_affiliation_strings":["Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062941634","display_name":"Haruyuki Atomi","orcid":"https://orcid.org/0000-0001-9687-6426","observed_orcids":["https://orcid.org/0000-0001-9687-6426"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Haruyuki Atomi","raw_affiliation_strings":["Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan","JST, CREST, Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"JST, CREST, Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan","institution_ids":["https://openalex.org/I4210086780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102071497","display_name":"Tadayuki Imanaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135768898","display_name":"Ritsumeikan University","ror":"https://ror.org/0197nmd03","country_code":"JP","type":"education","lineage":["https://openalex.org/I135768898","https://openalex.org/I4390039241"]},{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tadayuki Imanaka","raw_affiliation_strings":["Department of Biotechnology, College of Life Sciences, Ritsumeikan University, Noji-Higashi, Kusatsu 525-8577, Japan","JST, CREST, Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, College of Life Sciences, Ritsumeikan University, Noji-Higashi, Kusatsu 525-8577, Japan","institution_ids":["https://openalex.org/I135768898"]},{"raw_affiliation_string":"JST, CREST, Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan","institution_ids":["https://openalex.org/I4210086780"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5102071497"],"corresponding_institution_ids":["https://openalex.org/I135768898","https://openalex.org/I4210086780"],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":1.9259,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.8639613,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"81","issue":"5","first_page":"1300","last_page":"1312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12688","display_name":"Microbial metabolism and enzyme function","score":0.2581000030040741,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12688","display_name":"Microbial metabolism and enzyme function","score":0.2581000030040741,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.22200000286102295,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.1582999974489212,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thermococcus-kodakarensis","display_name":"Thermococcus kodakarensis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/glyceraldehyde-3-phosphate","display_name":"glyceraldehyde-3-phosphate","score":0.9509999752044678},{"id":"https://openalex.org/keywords/3-phosphoglycerate","display_name":"3-phosphoglycerate","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glycolysis","display_name":"glycolysis","score":0.859000027179718},{"id":"https://openalex.org/keywords/gluconeogenesis","display_name":"gluconeogenesis","score":0.7670000195503235},{"id":"https://openalex.org/keywords/phosphoglycerate-kinase","display_name":"phosphoglycerate kinase","score":0.9800000190734863},{"id":"https://openalex.org/keywords/gene-disruption","display_name":"gene disruption","score":0.6959999799728394},{"id":"https://openalex.org/keywords/nadph-production","display_name":"NADPH production","score":0.6809999942779541},{"id":"https://openalex.org/keywords/reduced-ferredoxin","display_name":"reduced ferredoxin","score":0.8920000195503235},{"id":"https://openalex.org/keywords/glucose-1-phosphate","display_name":"glucose-1-phosphate","score":0.9120000004768372},{"id":"https://openalex.org/keywords/euryarchaeota","display_name":"Euryarchaeota","score":0.7139999866485596},{"id":"https://openalex.org/keywords/archaeal-metabolism","display_name":"archaeal metabolism","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8915001153945923},{"id":"https://openalex.org/C2778899470","wikidata":"https://www.wikidata.org/wiki/Q2710532","display_name":"Thermococcus","level":4,"score":0.8458701968193054},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5774562358856201},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.42170044779777527},{"id":"https://openalex.org/C2781272698","wikidata":"https://www.wikidata.org/wiki/Q423211","display_name":"Glyceraldehyde","level":4,"score":0.4159452021121979},{"id":"https://openalex.org/C550995028","wikidata":"https://www.wikidata.org/wiki/Q10872","display_name":"Archaea","level":3,"score":0.270952045917511},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2453831434249878},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1900792419910431},{"id":"https://openalex.org/C2776317432","wikidata":"https://www.wikidata.org/wiki/Q412547","display_name":"Dehydrogenase","level":3,"score":0.06545230746269226}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005943","descriptor_name":"Gluconeogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005943","descriptor_name":"Gluconeogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005986","descriptor_name":"Glyceraldehyde 3-Phosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005987","descriptor_name":"Glyceraldehyde-3-Phosphate Dehydrogenases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005987","descriptor_name":"Glyceraldehyde-3-Phosphate Dehydrogenases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005988","descriptor_name":"Glyceric Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009249","descriptor_name":"NADP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010735","descriptor_name":"Phosphoglycerate Kinase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010735","descriptor_name":"Phosphoglycerate Kinase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017384","descriptor_name":"Sequence Deletion","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019712","descriptor_name":"Thermococcus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019712","descriptor_name":"Thermococcus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D024581","descriptor_name":"Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024581","descriptor_name":"Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-2958.2011.07762.x","doi":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2011.07762.x","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},{"id":"pmid:21736643","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21736643","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular microbiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1365-2958.2011.07762.x","doi":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2958.2011.07762.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2011.07762.x","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2113677520.pdf","grobid_xml":"https://content.openalex.org/works/W2113677520.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W78895978","https://openalex.org/W1493290107","https://openalex.org/W1507468227","https://openalex.org/W1525055187","https://openalex.org/W1563363363","https://openalex.org/W1598298585","https://openalex.org/W1604280659","https://openalex.org/W1971277373","https://openalex.org/W1981159620","https://openalex.org/W1981379996","https://openalex.org/W1985703657","https://openalex.org/W1988132327","https://openalex.org/W1990769556","https://openalex.org/W2002477714","https://openalex.org/W2009758786","https://openalex.org/W2019252943","https://openalex.org/W2019306769","https://openalex.org/W2020290718","https://openalex.org/W2023656126","https://openalex.org/W2029063714","https://openalex.org/W2043346581","https://openalex.org/W2047077981","https://openalex.org/W2050019714","https://openalex.org/W2053005601","https://openalex.org/W2054458212","https://openalex.org/W2057704466","https://openalex.org/W2060596399","https://openalex.org/W2065876515","https://openalex.org/W2067416774","https://openalex.org/W2070266683","https://openalex.org/W2071205438","https://openalex.org/W2072983595","https://openalex.org/W2073354998","https://openalex.org/W2073814577","https://openalex.org/W2077875794","https://openalex.org/W2080655621","https://openalex.org/W2083550208","https://openalex.org/W2084738041","https://openalex.org/W2094993739","https://openalex.org/W2095297536","https://openalex.org/W2098670258","https://openalex.org/W2103137020","https://openalex.org/W2103837827","https://openalex.org/W2111918410","https://openalex.org/W2113150793","https://openalex.org/W2131272473","https://openalex.org/W2143918999","https://openalex.org/W2145206794","https://openalex.org/W2147670977","https://openalex.org/W2151238119","https://openalex.org/W2153375590","https://openalex.org/W2156099263","https://openalex.org/W2158419708","https://openalex.org/W6999277025"],"related_works":["https://openalex.org/W2083550208","https://openalex.org/W2905623623","https://openalex.org/W2059984941","https://openalex.org/W1988132327","https://openalex.org/W2047077981","https://openalex.org/W2153090251","https://openalex.org/W2584097850","https://openalex.org/W2070576667","https://openalex.org/W1561239564","https://openalex.org/W2790644432"],"abstract_inverted_index":{"In":[0,29,55],"the":[1,8,30,59,63,74,149,160],"classical":[2,161],"Embden-Meyerhof":[3],"(EM)":[4],"pathway":[5],"for":[6,107],"glycolysis,":[7],"conversion":[9],"between":[10],"glyceraldehyde":[11],"3-phosphate":[12],"(GAP)":[13],"and":[14,25,34,44,69,78,84,138,151,191],"3-phosphoglycerate":[15],"(3-PGA)":[16],"is":[17],"reversibly":[18],"catalysed":[19],"by":[20],"phosphorylating":[21],"GAP":[22,50,68],"dehydrogenase":[23,51],"(GAPDH)":[24],"phosphoglycerate":[26],"kinase":[27],"(PGK).":[28],"Euryarchaeota":[31],"Thermococcus":[32],"kodakarensis":[33,177],"Pyrococcus":[35],"furiosus,":[36],"an":[37],"additional":[38],"gene":[39,46],"encoding":[40],"GAP:ferredoxin":[41],"oxidoreductase":[42],"(GAPOR)":[43],"a":[45,126,166],"similar":[47],"to":[48,57,103],"non-phosphorylating":[49],"(GAPN)":[52],"are":[53],"present.":[54],"order":[56],"determine":[58],"physiological":[60],"roles":[61],"of":[62,87,136],"three":[64],"routes":[65],"that":[66,123,175],"link":[67],"3-PGA,":[70],"we":[71],"individually":[72],"disrupted":[73],"GAPOR,":[75],"GAPN,":[76],"GAPDH":[77],"PGK":[79],"genes":[80],"(gor,":[81],"gapN,":[82],"gapDH":[83],"pgk":[85],"respectively)":[86],"T.":[88,176],"kodakarensis.":[89],"The":[90],"\u0394gor":[91],"strain":[92],"displayed":[93],"no":[94,141],"growth":[95],"under":[96,119,132],"glycolytic":[97,120],"conditions,":[98,121],"confirming":[99],"its":[100],"proposed":[101],"function":[102],"generate":[104],"reduced":[105],"ferredoxin":[106],"energy":[108],"generation":[109],"in":[110,129,159,170],"glycolysis.":[111],"Surprisingly,":[112],"\u0394gapN":[113],"cells":[114],"also":[115],"did":[116,179],"not":[117,180],"grow":[118],"suggesting":[122],"GAPN":[124,178],"plays":[125],"key":[127],"role":[128,168],"providing":[130],"NADPH":[131],"these":[133],"conditions.":[134],"Disruption":[135],"gor":[137],"gapN":[139],"had":[140],"effect":[142],"on":[143],"gluconeogenic":[144],"growth.":[145],"Growth":[146],"experiments":[147],"with":[148,195],"\u0394gapDH":[150],"\u0394pgk":[152],"strains":[153],"indicated":[154,174],"that,":[155],"unlike":[156],"their":[157],"counterparts":[158],"EM":[162],"pathway,":[163],"GAPDH/PGK":[164],"play":[165],"major":[167],"only":[169],"gluconeogenesis.":[171],"Biochemical":[172],"analyses":[173],"recognize":[181],"aldehyde":[182],"substrates":[183],"other":[184],"than":[185],"d-GAP,":[186],"preferred":[187],"NADP(+)":[188],"as":[189],"cofactor":[190],"was":[192],"dramatically":[193],"activated":[194],"glucose":[196],"1-phosphate.":[197]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}