{"id":"https://openalex.org/W2113549477","doi":"https://doi.org/10.1016/s0196-9781(98)00097-7","title":"Prolongation of intermeal interval by gastrin-releasing peptide depends upon time of delivery","display_name":"Prolongation of intermeal interval by gastrin-releasing peptide depends upon time of delivery","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2113549477","doi":"https://doi.org/10.1016/s0196-9781(98)00097-7","mag":"2113549477","pmid":"https://pubmed.ncbi.nlm.nih.gov/9809660"},"language":"en","primary_location":{"id":"doi:10.1016/s0196-9781(98)00097-7","doi":"https://doi.org/10.1016/s0196-9781(98)00097-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0196-9781(98)00097-7","pdf_url":null,"source":{"id":"https://openalex.org/S120382301","display_name":"Peptides","issn_l":"0196-9781","issn":["0196-9781","1873-5169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/s0196-9781(98)00097-7","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109109673","display_name":"Paul A. Rushing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A. Rushing","raw_affiliation_strings":["Department of Psychiatry, Cornell University Medical College, New York Hospital-Cornell Medical Center, White Plains 10605, USA. prushing@psyche.uc.edu","Department of Psychiatry, Cornell University Medical College, and Edward W. Bourne Behavioral Research Laboratory, New York Hospital-Cornell Medical Center, White Plains, NY 10605 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Cornell University Medical College, New York Hospital-Cornell Medical Center, White Plains 10605, USA. prushing@psyche.uc.edu","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Department of Psychiatry, Cornell University Medical College, and Edward W. Bourne Behavioral Research Laboratory, New York Hospital-Cornell Medical Center, White Plains, NY 10605 USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110210635","display_name":"James Gibbs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Gibbs","raw_affiliation_strings":["Department of Psychiatry, Cornell University Medical College, and Edward W. Bourne Behavioral Research Laboratory, New York Hospital-Cornell Medical Center, White Plains, NY 10605 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Cornell University Medical College, and Edward W. Bourne Behavioral Research Laboratory, New York Hospital-Cornell Medical Center, White Plains, NY 10605 USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":3710,"currency":"USD","value_usd":3710},"apc_paid":{"value":3710,"currency":"USD","value_usd":3710},"fwci":0.2441,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.43264326,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"19","issue":"8","first_page":"1439","last_page":"1442"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.06669999659061432,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastrin-releasing-peptide","display_name":"gastrin-releasing peptide","score":0.9929999709129333},{"id":"https://openalex.org/keywords/intermeal-interval","display_name":"intermeal interval","score":0.9049999713897705},{"id":"https://openalex.org/keywords/postprandial-satiety","display_name":"postprandial satiety","score":0.7419999837875366},{"id":"https://openalex.org/keywords/meal-termination","display_name":"meal termination","score":0.5550000071525574},{"id":"https://openalex.org/keywords/nocturnal-foraging","display_name":"nocturnal feeding","score":0.7020000219345093},{"id":"https://openalex.org/keywords/meal-size","display_name":"meal size","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C2778345441","wikidata":"https://www.wikidata.org/wiki/Q6460735","display_name":"Meal","level":2,"score":0.7900974750518799},{"id":"https://openalex.org/C2776998989","wikidata":"https://www.wikidata.org/wiki/Q642462","display_name":"Gastrin-releasing peptide","level":5,"score":0.7231372594833374},{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.6660953760147095},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6085006594657898},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5925911068916321},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5442245006561279},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.5383779406547546},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.4982757568359375},{"id":"https://openalex.org/C2776986829","wikidata":"https://www.wikidata.org/wiki/Q407181","display_name":"Gastrin","level":3,"score":0.47981882095336914},{"id":"https://openalex.org/C2778448772","wikidata":"https://www.wikidata.org/wiki/Q349427","display_name":"Bombesin","level":4,"score":0.4303063154220581},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.3567816913127899},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3491206765174866},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.2513396739959717},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20131349563598633},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012528","descriptor_name":"Satiety Response","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019886","descriptor_name":"Gastrin-Releasing Peptide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0196-9781(98)00097-7","doi":"https://doi.org/10.1016/s0196-9781(98)00097-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0196-9781(98)00097-7","pdf_url":null,"source":{"id":"https://openalex.org/S120382301","display_name":"Peptides","issn_l":"0196-9781","issn":["0196-9781","1873-5169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"journal-article"},{"id":"pmid:9809660","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9809660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0196-9781(98)00097-7","doi":"https://doi.org/10.1016/s0196-9781(98)00097-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0196-9781(98)00097-7","pdf_url":null,"source":{"id":"https://openalex.org/S120382301","display_name":"Peptides","issn_l":"0196-9781","issn":["0196-9781","1873-5169"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Peptides","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2159447404","display_name":null,"funder_award_id":"DK33248","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3336280018","display_name":"POSTDOCTORAL TRAINING IN EATING DISORDERS","funder_award_id":"T32MH018390","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W129480248","https://openalex.org/W1975405734","https://openalex.org/W1982112451","https://openalex.org/W2069330805","https://openalex.org/W2075815329","https://openalex.org/W2081230878","https://openalex.org/W2500471623","https://openalex.org/W4300721599"],"related_works":["https://openalex.org/W2081230878","https://openalex.org/W2024432197","https://openalex.org/W2031108469","https://openalex.org/W2092129376","https://openalex.org/W1966275433","https://openalex.org/W7096819775","https://openalex.org/W1966242219","https://openalex.org/W2019092378","https://openalex.org/W2072887314","https://openalex.org/W1971583390"],"abstract_inverted_index":{"We":[0],"have":[1],"previously":[2],"shown":[3],"that":[4,206],"brief,":[5],"vena":[6,82],"caval":[7,83],"infusion":[8,116],"of":[9,20,37,95,106,125,141,155,172,190,223],"gastrin-releasing":[10],"peptide1-27":[11],"(GRP),":[12],"delivered":[13,58,134],"shortly":[14,215],"(5":[15],"min)":[16],"after":[17,103,139,176,216],"the":[18,21,28,35,38,45,52,60,67,104,107,142,149,183,188,191,204,221,224],"end":[19,105],"first":[22,108,143],"spontaneous":[23,109],"nocturnal":[24,110,144],"meal,":[25,145],"significantly":[26,147,181],"prolongs":[27],"postprandial":[29],"intermeal":[30],"interval":[31],"(IMI)":[32],"without":[33],"affecting":[34],"size":[36,189],"subsequent":[39,192],"meal":[40,177,193,217],"in":[41,210],"freely-feeding":[42],"rats.":[43],"In":[44],"present":[46],"study,":[47],"we":[48],"tested":[49],"whether":[50],"varying":[51],"time":[53],"at":[54],"which":[55],"GRP":[56,96,146,173,208],"was":[57,194],"during":[59],"IMI":[61,150],"affected":[62],"its":[63],"ability":[64],"to":[65,160,219],"prolong":[66],"interval.":[68],"Specifically,":[69],"rats":[70],"(n":[71],"=":[72],"9),":[73],"fed":[74],"milk":[75],"ad":[76],"lib":[77],"and":[78,123,131,165],"with":[79,90,203,212],"indwelling":[80],"inferior":[81],"catheters,":[84],"were":[85,128],"infused":[86],"for":[87],"1":[88],"min":[89,102,138,159,164,175],"saline":[91],"or":[92,100,136],"10":[93],"nmol/kg":[94],"either":[97],"5,":[98],"15,":[99],"30":[101,174],"meal.":[111],"Each":[112],"received":[113],"a":[114,152],"single":[115],"on":[117,187],"any":[118,197],"given":[119],"test":[120],"day.":[121],"Infusions":[122],"recording":[124],"individual":[126],"licks":[127],"fully":[129],"automated":[130],"computer-controlled.":[132],"When":[133],"5":[135],"15":[137],"termination":[140,178,218],"increased":[148],"from":[151],"control":[153],"level":[154],"82":[156],"+/-":[157,162,167],"12":[158],"111":[161],"13":[163],"106":[166],"18":[168],"min,":[169],"respectively.":[170],"Infusion":[171],"did":[179],"not":[180],"alter":[182],"IMI.":[184,225],"No":[185],"effect":[186],"observed":[195],"under":[196],"condition.":[198],"These":[199],"results":[200],"are":[201],"consistent":[202],"hypothesis":[205],"endogenous":[207],"acts":[209],"conjunction":[211],"events":[213],"occurring":[214],"extend":[220],"duration":[222]},"counts_by_year":[{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}