{"id":"https://openalex.org/W2113293128","doi":"https://doi.org/10.3109/02713683.2011.574330","title":"Changes of Aquaporins in the Lacrimal Glands of a Rabbit Model of Sj\u00f6gren\u2019s Syndrome","display_name":"Changes of Aquaporins in the Lacrimal Glands of a Rabbit Model of Sj\u00f6gren\u2019s Syndrome","publication_year":2011,"publication_date":"2011-04-27","ids":{"openalex":"https://openalex.org/W2113293128","doi":"https://doi.org/10.3109/02713683.2011.574330","mag":"2113293128","pmid":"https://pubmed.ncbi.nlm.nih.gov/21524183","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3636994"},"language":"en","primary_location":{"id":"doi:10.3109/02713683.2011.574330","doi":"https://doi.org/10.3109/02713683.2011.574330","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02713683.2011.574330","pdf_url":null,"source":{"id":"https://openalex.org/S74941265","display_name":"Current Eye Research","issn_l":"0271-3683","issn":["0271-3683","1460-2202"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Eye Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3636994","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101881767","display_name":"Chuanqing Ding","orcid":"https://orcid.org/0000-0003-4773-9374","observed_orcids":["https://orcid.org/0000-0003-4773-9374"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chuanqing Ding","raw_affiliation_strings":["Department of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California 90089-9112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California 90089-9112, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010897436","display_name":"Prachi Nandoskar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prachi Nandoskar","raw_affiliation_strings":["Department of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103032216","display_name":"Michael Lu","orcid":"https://orcid.org/0000-0002-7898-7867","observed_orcids":["https://orcid.org/0000-0002-7898-7867"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Lu","raw_affiliation_strings":["Department of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103468816","display_name":"Padmaja B. Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Padmaja Thomas","raw_affiliation_strings":["Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071906900","display_name":"Melvin D. Trousdale","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095445","display_name":"Doheny Eye Institute","ror":"https://ror.org/00qvx5329","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210095445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melvin D. Trousdale","raw_affiliation_strings":["Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210095445"]}]},{"author_position":"last","author":{"id":null,"display_name":"Yanru Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanru Wang","raw_affiliation_strings":["Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101881767"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":3.1382,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.90880223,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"36","issue":"6","first_page":"571","last_page":"578"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.8398000001907349,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.8398000001907349,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.10819999873638153,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.04089999943971634,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aquaporins","display_name":"aquaporins","score":0.8679999709129333},{"id":"https://openalex.org/keywords/aquaporin-4","display_name":"aquaporin-4","score":0.925000011920929},{"id":"https://openalex.org/keywords/aqp5","display_name":"aquaporin 5","score":1.0},{"id":"https://openalex.org/keywords/lacrimal-gland","display_name":"lacrimal gland","score":0.9409999847412109},{"id":"https://openalex.org/keywords/sjogren-s-syndrome","display_name":"Sj\u00f6gren's syndrome","score":0.9570000171661377},{"id":"https://openalex.org/keywords/tear-production","display_name":"tear secretion","score":0.8889999985694885},{"id":"https://openalex.org/keywords/acinar-cells","display_name":"acinar cells","score":0.7289999723434448},{"id":"https://openalex.org/keywords/ductal-cells","display_name":"ductal cells","score":0.8880000114440918},{"id":"https://openalex.org/keywords/rabbit-model","display_name":"rabbit model","score":0.8209999799728394},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C154280991","wikidata":"https://www.wikidata.org/wiki/Q623090","display_name":"Aquaporin","level":2,"score":0.8093686699867249},{"id":"https://openalex.org/C2778148616","wikidata":"https://www.wikidata.org/wiki/Q5311600","display_name":"Ductal cells","level":3,"score":0.7303520441055298},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.7101597785949707},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.6440860629081726},{"id":"https://openalex.org/C2779298748","wikidata":"https://www.wikidata.org/wiki/Q913628","display_name":"Lacrimal gland","level":2,"score":0.6354546546936035},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.552802562713623},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5169738531112671},{"id":"https://openalex.org/C2780446580","wikidata":"https://www.wikidata.org/wiki/Q346854","display_name":"Acinus","level":3,"score":0.4627893269062042},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.4479059875011444},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4215562343597412},{"id":"https://openalex.org/C15755913","wikidata":"https://www.wikidata.org/wiki/Q14902502","display_name":"Aquaporin 4","level":2,"score":0.4120088517665863},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3851515054702759},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.358238160610199},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2511163055896759},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.24899399280548096},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22656899690628052},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.19541841745376587},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16125234961509705},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06128883361816406},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007765","descriptor_name":"Lacrimal Apparatus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007765","descriptor_name":"Lacrimal Apparatus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020346","descriptor_name":"Aquaporins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D020346","descriptor_name":"Aquaporins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051401","descriptor_name":"Aquaporin 4","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D051401","descriptor_name":"Aquaporin 4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051402","descriptor_name":"Aquaporin 5","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D051402","descriptor_name":"Aquaporin 5","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3109/02713683.2011.574330","doi":"https://doi.org/10.3109/02713683.2011.574330","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02713683.2011.574330","pdf_url":null,"source":{"id":"https://openalex.org/S74941265","display_name":"Current Eye Research","issn_l":"0271-3683","issn":["0271-3683","1460-2202"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Eye Research","raw_type":"journal-article"},{"id":"pmid:21524183","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21524183","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current eye research","raw_type":"Comparative Study"},{"id":"pmh:oai:europepmc.org:2632780","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3636994","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3636994","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3636994","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Eye Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2632780","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3636994","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8999999761581421}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":0.8199999928474426}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1396024002","display_name":"Core Grant for Vision Research","funder_award_id":"P30EY003040","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G1804614368","display_name":"Prolactin as a lacrimal gland immunomodulator","funder_award_id":"R56EY010550","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G199691145","display_name":null,"funder_award_id":"DK048522","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2453337557","display_name":null,"funder_award_id":"#EY03040","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G2613059553","display_name":"Functional Regulation of the Lacrimal Duct System","funder_award_id":"R01EY017731","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G2784945491","display_name":null,"funder_award_id":"EY010550","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G3677763465","display_name":null,"funder_award_id":"EY-012689","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G390273779","display_name":null,"funder_award_id":"EY005801","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5636324992","display_name":"Prolactin as a Lacrimal Gland Immunoregulator","funder_award_id":"R01EY010550","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6095640204","display_name":null,"funder_award_id":"EY 017731","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6262137844","display_name":"Anti-Inflammatory Genes in Autoimmune Dacryoadenitis","funder_award_id":"R01EY012689","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6656639576","display_name":"Basal-Lateral/Endomembrane Traffic in Lacrimal Acini","funder_award_id":"R01EY005801","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G7609147157","display_name":"USC Research Center for Liver Disease","funder_award_id":"P30DK048522","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W136654495","https://openalex.org/W1850523969","https://openalex.org/W1971143113","https://openalex.org/W1974212951","https://openalex.org/W1985792221","https://openalex.org/W1986968716","https://openalex.org/W1990751721","https://openalex.org/W1993371622","https://openalex.org/W1997752081","https://openalex.org/W1998828079","https://openalex.org/W1999877232","https://openalex.org/W2014735730","https://openalex.org/W2019232650","https://openalex.org/W2021501256","https://openalex.org/W2042279757","https://openalex.org/W2042702617","https://openalex.org/W2043386863","https://openalex.org/W2047279603","https://openalex.org/W2047960530","https://openalex.org/W2054176091","https://openalex.org/W2063869515","https://openalex.org/W2065663928","https://openalex.org/W2065975622","https://openalex.org/W2068730691","https://openalex.org/W2071783697","https://openalex.org/W2074680272","https://openalex.org/W2082304601","https://openalex.org/W2085072839","https://openalex.org/W2089803590","https://openalex.org/W2092800155","https://openalex.org/W2102946022","https://openalex.org/W2115956096","https://openalex.org/W2121594383","https://openalex.org/W2126540779","https://openalex.org/W2149738087","https://openalex.org/W2186616911","https://openalex.org/W2261051929"],"related_works":["https://openalex.org/W6889439568","https://openalex.org/W2065663928","https://openalex.org/W2126540779","https://openalex.org/W136654495","https://openalex.org/W2120489631","https://openalex.org/W2372106180","https://openalex.org/W1990751721","https://openalex.org/W3196732002","https://openalex.org/W3213460432","https://openalex.org/W2074680272"],"abstract_inverted_index":{"AIMS:":[0],"To":[1],"test":[2],"the":[3,6,17,61,123,150,182],"hypothesis":[4,258],"that":[5,149,175,259,270],"expression":[7,151],"of":[8,21,65,69,93,108,152,185,212,261],"aquaporins":[9],"(AQPs)":[10],"4":[11],"and":[12,40,58,63,67,71,76,80,97,187,192,209,215,269],"5":[13],"is":[14],"altered":[15,264],"in":[16,73,114,131,142,154,190,236,248,265,277],"lacrimal":[18,278],"glands":[19],"(LG)":[20],"rabbits":[22,37,89,119,134,157,249,266],"with":[23,38,90,120,135,158,195,221,250,267],"induced":[24],"autoimmune":[25],"dacryoadenitis":[26],"(IAD).":[27],"MATERIALS":[28],"AND":[29],"METHODS:":[30],"LGs":[31,45,101,155],"were":[32,46,102,112],"obtained":[33],"from":[34,83,99,118,133,156,239],"adult":[35],"female":[36,42],"IAD,":[39,91,136,268],"age-matched":[41],"control":[43,191,240],"rabbits.":[44],"processed":[47],"for":[48,60,95,110,126],"laser":[49],"capture":[50],"microdissection":[51],"(LCM),":[52],"real":[53],"time":[54],"RT-PCR,":[55],"Western":[56,146],"blot,":[57],"immunofluorescence":[59],"detection":[62],"quantification":[64],"protein":[66],"mRNAs":[68,94],"AQP4":[70,96,111,153,176],"AQP5":[72,98,127,168],"whole":[74,100],"LGs,":[75,194],"purified":[77],"acinar":[78,186,202,213,225],"cells":[79,82,189,197,226,238],"duct":[81,85,116,144],"specific":[84,271],"segments.":[86],"RESULTS:":[87],"In":[88],"abundances":[92],"significantly":[103,129,246],"lower":[104,113,130],"than":[105,164,201,230],"controls.":[106],"Levels":[107],"mRNA":[109,124],"most":[115],"segments":[117],"IAD.":[121,251],"However,":[122],"abundance":[125,139],"was":[128,140,160,169,179,205,234,245],"acini":[132,223],"while":[137,242],"its":[138,243],"higher":[141],"each":[143],"segment.":[145],"blot":[147],"showed":[148,216],"IAD":[159],"36%":[161],"more":[162],"abundant":[163],"normal":[165],"controls,":[166],"whereas":[167],"72%":[170],"less":[171],"abundant.":[172],"Immunofluorescence":[173],"indicated":[174],"immunoreactivity":[177],"(AQP4-IR)":[178],"present":[180],"on":[181,207],"basolateral":[183,210],"membranes":[184,211],"ductal":[188,196,237,272],"diseased":[193],"showing":[198,227],"stronger":[199,228],"AQP4-IR":[200],"cells.":[203],"AQP5-IR":[204,229,233],"found":[206],"apical":[208],"cells,":[214],"a":[217],"\"mosaic\"":[218],"pattern,":[219],"i.e.,":[220],"some":[222],"and/or":[224],"others.":[231],"Minimal":[232],"detected":[235],"animals,":[241],"intensity":[244],"increased":[247],"CONCLUSIONS:":[252],"These":[253],"data":[254],"strongly":[255],"support":[256],"our":[257],"expressions":[260],"AQPs":[262],"are":[263],"segment":[273],"play":[274],"important":[275],"roles":[276],"secretion.":[279]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}