{"id":"https://openalex.org/W2112349784","doi":"https://doi.org/10.1128/iai.65.10.4288-4298.1997","title":"Targeted delivery of antigen to hamster nasal lymphoid tissue with M-cell-directed lectins","display_name":"Targeted delivery of antigen to hamster nasal lymphoid tissue with M-cell-directed lectins","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W2112349784","doi":"https://doi.org/10.1128/iai.65.10.4288-4298.1997","mag":"2112349784","pmid":"https://pubmed.ncbi.nlm.nih.gov/9317039","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/175615"},"language":"en","primary_location":{"id":"doi:10.1128/iai.65.10.4288-4298.1997","doi":"https://doi.org/10.1128/iai.65.10.4288-4298.1997","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.65.10.4288-4298.1997","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC175615","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041244892","display_name":"Paul J. Giannasca","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"P J Giannasca","raw_affiliation_strings":["OraVax, Inc., Cambridge, Massachusetts 02139, USA. pgiannas@oravax.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OraVax, Inc., Cambridge, Massachusetts 02139, USA. pgiannas@oravax.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111902313","display_name":"Joan A. Boden","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"J A Boden","raw_affiliation_strings":["OraVax, Inc., Cambridge, Massachusetts 02139, USA. pgiannas@oravax.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OraVax, Inc., Cambridge, Massachusetts 02139, USA. pgiannas@oravax.com","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055066987","display_name":"Thomas P. C. Monath","orcid":"https://orcid.org/0000-0001-7509-4599","observed_orcids":["https://orcid.org/0000-0001-7509-4599"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"T P Monath","raw_affiliation_strings":["OraVax, Inc., Cambridge, Massachusetts 02139, USA. pgiannas@oravax.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OraVax, Inc., Cambridge, Massachusetts 02139, USA. pgiannas@oravax.com","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041244892","https://openalex.org/A5055066987","https://openalex.org/A5111902313"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.5804,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.99229739,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"65","issue":"10","first_page":"4288","last_page":"4298"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.4713999927043915,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.4713999927043915,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.2401999980211258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.22470000386238098,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/m-cells","display_name":"M cells","score":0.9359999895095825},{"id":"https://openalex.org/keywords/nasal-associated-lymphoid-tissue","display_name":"nasal-associated lymphoid tissue","score":0.8970000147819519},{"id":"https://openalex.org/keywords/lectins","display_name":"lectins","score":0.5920000076293945},{"id":"https://openalex.org/keywords/follicle-associated-epithelium","display_name":"follicle-associated epithelium","score":0.8989999890327454},{"id":"https://openalex.org/keywords/mucosal-immunity","display_name":"mucosal immunity","score":0.6949999928474426},{"id":"https://openalex.org/keywords/intranasal-immunization","display_name":"intranasal immunization","score":0.8180000185966492},{"id":"https://openalex.org/keywords/hamster","display_name":"hamster","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C13426554","wikidata":"https://www.wikidata.org/wiki/Q416019","display_name":"Glycoconjugate","level":2,"score":0.7972077131271362},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7968826293945312},{"id":"https://openalex.org/C2780758401","wikidata":"https://www.wikidata.org/wiki/Q408693","display_name":"Lectin","level":2,"score":0.7675734758377075},{"id":"https://openalex.org/C43667030","wikidata":"https://www.wikidata.org/wiki/Q1815955","display_name":"Microfold cell","level":3,"score":0.678807258605957},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6365247964859009},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4958871304988861},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49455639719963074},{"id":"https://openalex.org/C87568996","wikidata":"https://www.wikidata.org/wiki/Q1428754","display_name":"Respiratory epithelium","level":3,"score":0.4417092204093933},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.4146007001399994},{"id":"https://openalex.org/C2778082330","wikidata":"https://www.wikidata.org/wiki/Q1941426","display_name":"Griffonia simplicifolia","level":3,"score":0.4116842746734619},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3507288098335266},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3392907977104187},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07078936696052551},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000281","descriptor_name":"Administration, Intranasal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005697","descriptor_name":"Galactosides","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D005697","descriptor_name":"Galactosides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006001","descriptor_name":"Glycoconjugates","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D006001","descriptor_name":"Glycoconjugates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006651","descriptor_name":"Histocytochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008221","descriptor_name":"Lymphoid Tissue","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008221","descriptor_name":"Lymphoid Tissue","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008221","descriptor_name":"Lymphoid Tissue","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008647","descriptor_name":"Mesocricetus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014611","descriptor_name":"Vaccination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018998","descriptor_name":"Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D018998","descriptor_name":"Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1128/iai.65.10.4288-4298.1997","doi":"https://doi.org/10.1128/iai.65.10.4288-4298.1997","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.65.10.4288-4298.1997","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:225598","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC175615","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:175615","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/175615","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:9317039","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9317039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.321.442","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.321.442","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://iai.asm.org/content/65/10/4288.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:225598","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC175615","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W590565482","https://openalex.org/W1238880271","https://openalex.org/W1491449586","https://openalex.org/W1506981307","https://openalex.org/W1507836923","https://openalex.org/W1508075941","https://openalex.org/W1533411461","https://openalex.org/W1534872489","https://openalex.org/W1539696212","https://openalex.org/W1567197932","https://openalex.org/W1570367374","https://openalex.org/W1572573094","https://openalex.org/W1577158615","https://openalex.org/W1582740266","https://openalex.org/W1593332011","https://openalex.org/W1675056235","https://openalex.org/W1962773487","https://openalex.org/W1969146717","https://openalex.org/W1969635870","https://openalex.org/W1980737380","https://openalex.org/W1980935333","https://openalex.org/W1982877988","https://openalex.org/W1986711154","https://openalex.org/W1987556227","https://openalex.org/W1988335886","https://openalex.org/W1990035528","https://openalex.org/W1992357348","https://openalex.org/W1998483894","https://openalex.org/W2004415744","https://openalex.org/W2008023397","https://openalex.org/W2018161699","https://openalex.org/W2023353270","https://openalex.org/W2025591240","https://openalex.org/W2027416880","https://openalex.org/W2030807118","https://openalex.org/W2039104234","https://openalex.org/W2044711856","https://openalex.org/W2047178148","https://openalex.org/W2055691615","https://openalex.org/W2058103296","https://openalex.org/W2058539196","https://openalex.org/W2063453699","https://openalex.org/W2071536249","https://openalex.org/W2091483311","https://openalex.org/W2091814109","https://openalex.org/W2094725513","https://openalex.org/W2100275007","https://openalex.org/W2100563684","https://openalex.org/W2113472548","https://openalex.org/W2128763987","https://openalex.org/W2139837356","https://openalex.org/W2141473188","https://openalex.org/W2143105928","https://openalex.org/W2158398996","https://openalex.org/W2158727946","https://openalex.org/W2158946800","https://openalex.org/W2160332837","https://openalex.org/W2167933104","https://openalex.org/W2281217012","https://openalex.org/W2292337439","https://openalex.org/W2334099783","https://openalex.org/W2401149223","https://openalex.org/W2483835641","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2051615865","https://openalex.org/W2018912670","https://openalex.org/W2128763987","https://openalex.org/W2281217012","https://openalex.org/W2100563684","https://openalex.org/W2072399143","https://openalex.org/W2152432500","https://openalex.org/W2018706696","https://openalex.org/W1986711154","https://openalex.org/W2019136082"],"abstract_inverted_index":{"The":[0,49,203,263],"nasal":[1,23,33,118,187],"cavity":[2,34,119],"of":[3,22,31,40,42,62,104,115,123,127,152,233,249,266,291],"a":[4,121,193,271,276],"rodent":[5],"is":[6],"lined":[7],"by":[8,78,270],"an":[9,189],"epithelium":[10,50,107,162],"organized":[11],"into":[12],"distinct":[13,79],"regional":[14],"domains":[15],"responsible":[16],"for":[17,59,278],"specific":[18,250],"physiological":[19],"functions.":[20],"Aggregates":[21],"lymphoid":[24],"tissue":[25],"(NALT)":[26],"located":[27],"at":[28],"the":[29,32,60,105,116,145,160,169,186,211,214,231,288],"base":[30],"are":[35,57,76],"believed":[36],"to":[37,46,89,141,158,201,208,221,293],"be":[38],"sites":[39,142],"induction":[41,248],"mucosal":[43,68],"immune":[44,87],"responses":[45,88],"airborne":[47],"antigens.":[48,91],"overlying":[51],"NALT":[52,73,98,267,294],"contains":[53,171],"M":[54,74,99,148,173,181,222,234,268,285],"cells":[55,75,100,103,133,182,223,235,269,286],"which":[56,82],"specialized":[58],"transcytosis":[61],"immunogens,":[63],"as":[64],"demonstrated":[65],"in":[66,134,196,224,236,273],"other":[67,102],"tissues.":[69],"We":[70],"hypothesized":[71],"that":[72,95],"characterized":[77],"glycoconjugate":[80],"receptors":[81],"influence":[83],"antigen":[84,237,243,255],"uptake":[85],"and":[86,147,192,287],"transcytosed":[90],"To":[92,175],"identify":[93],"glycoconjugates":[94,128,179],"may":[96],"distinguish":[97],"from":[101,185],"respiratory":[106],"(RE),":[108],"we":[109],"performed":[110],"lectin":[111,191,195,205,216,260,272],"histochemistry":[112],"on":[113,131,143,180,284],"sections":[114],"hamster":[117],"with":[120,230,241,259],"panel":[122],"lectins.":[124],"Many":[125],"classes":[126],"were":[129,156,183,198],"found":[130,157,207],"epithelial":[132],"this":[135],"region.":[136],"While":[137],"most":[138],"lectins":[139],"bound":[140,220],"both":[144],"RE":[146],"cells,":[149],"probes":[150],"capable":[151],"recognizing":[153],"alpha-linked":[154],"galactose":[155],"label":[159],"follicle-associated":[161],"(FAE)":[163],"almost":[164],"exclusively.":[165],"By":[166],"morphological":[167],"criteria,":[168],"FAE":[170],">90%":[172],"cells.":[174],"determine":[176],"if":[177],"apical":[178],"accessible":[184],"cavity,":[188],"M-cell-selective":[190,204],"control":[194,215],"parallel":[197],"administered":[199],"intranasally":[200],"hamsters.":[202],"was":[206,226],"specifically":[209],"target":[210],"FAE,":[212],"while":[213],"did":[217,261],"not.":[218,262],"Lectin":[219],"vivo":[225,274],"efficiently":[227],"endocytosed,":[228],"consistent":[229],"role":[232],"transport.":[238],"Intranasal":[239],"immunization":[240],"lectin-test":[242],"conjugates":[244],"without":[245],"adjuvant":[246],"stimulated":[247],"serum":[251],"immunoglobulin":[252],"G,":[253],"whereas":[254],"alone":[256],"or":[257],"admixed":[258],"selective":[264],"recognition":[265],"provides":[275],"model":[277],"microbial":[279],"adhesin-host":[280],"cell":[281],"receptor":[282],"interactions":[283],"targeted":[289],"delivery":[290],"immunogens":[292],"following":[295],"intranasal":[296],"administration.":[297]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}