{"id":"https://openalex.org/W2111511065","doi":null,"title":"Stochastic modeling of motor proteins","display_name":"Stochastic modeling of motor proteins","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2111511065","mag":"2111511065"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:kth-4664","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4664","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4664","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041057487","display_name":"Martin Lind\u00e9n","orcid":"https://orcid.org/0000-0003-4200-0191","observed_orcids":["https://orcid.org/0000-0003-4200-0191"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Martin Lind\u00e9n","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4200-0191","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041057487"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.6542999744415283,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.6542999744415283,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11520","display_name":"Advanced Thermodynamics and Statistical Mechanics","score":0.11999999731779099,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.10159999877214432,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/motor-proteins","display_name":"motor proteins","score":0.9990000128746033},{"id":"https://openalex.org/keywords/stochastic-modeling","display_name":"stochastic modeling","score":0.8460000157356262},{"id":"https://openalex.org/keywords/pilt","display_name":"pilT","score":0.6510000228881836},{"id":"https://openalex.org/keywords/first-passage-processes","display_name":"first-passage processes","score":0.6549999713897705},{"id":"https://openalex.org/keywords/stepwise-motion","display_name":"stepwise motion","score":0.593999981880188},{"id":"https://openalex.org/keywords/chemical-driving-force","display_name":"chemical driving force","score":0.8629999756813049},{"id":"https://openalex.org/keywords/single-molecule-studies","display_name":"single-molecule analysis","score":0.6060000061988831},{"id":"https://openalex.org/keywords/intracellular-transport","display_name":"intracellular transport","score":0.7730000019073486},{"id":"https://openalex.org/keywords/muscle-contraction","display_name":"muscle contraction","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C74859849","wikidata":"https://www.wikidata.org/wiki/Q2466686","display_name":"Non-equilibrium thermodynamics","level":2,"score":0.8069243431091309},{"id":"https://openalex.org/C158693339","wikidata":"https://www.wikidata.org/wiki/Q190524","display_name":"Eigenvalues and eigenvectors","level":2,"score":0.7560415863990784},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.682953953742981},{"id":"https://openalex.org/C128805008","wikidata":"https://www.wikidata.org/wiki/Q722878","display_name":"Master equation","level":3,"score":0.6126521229743958},{"id":"https://openalex.org/C8171440","wikidata":"https://www.wikidata.org/wiki/Q903414","display_name":"Steady state (chemistry)","level":2,"score":0.5989918112754822},{"id":"https://openalex.org/C141513077","wikidata":"https://www.wikidata.org/wiki/Q378542","display_name":"Independent and identically distributed random variables","level":3,"score":0.5645776987075806},{"id":"https://openalex.org/C189950617","wikidata":"https://www.wikidata.org/wiki/Q937228","display_name":"Property (philosophy)","level":2,"score":0.5133906602859497},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5062479376792908},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.47387978434562683},{"id":"https://openalex.org/C2777027219","wikidata":"https://www.wikidata.org/wiki/Q1284190","display_name":"Constant (computer programming)","level":2,"score":0.46568575501441956},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.46511605381965637},{"id":"https://openalex.org/C2779886137","wikidata":"https://www.wikidata.org/wiki/Q21030012","display_name":"Symmetry (geometry)","level":2,"score":0.4386464059352875},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.4202617108821869},{"id":"https://openalex.org/C186659197","wikidata":"https://www.wikidata.org/wiki/Q5452195","display_name":"First-hitting-time model","level":2,"score":0.41169261932373047},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3402605950832367},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.25590401887893677},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2556084990501404},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.24479928612709045},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2132989466190338},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.11952811479568481},{"id":"https://openalex.org/C122123141","wikidata":"https://www.wikidata.org/wiki/Q176623","display_name":"Random variable","level":2,"score":0.11133605241775513},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.08301305770874023},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C84114770","wikidata":"https://www.wikidata.org/wiki/Q46344","display_name":"Quantum","level":2,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:kth-4664","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4664","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2111511065","doi":null,"is_oa":false,"landing_page_url":"http://kth.diva-portal.org/smash/get/diva2:13313/FULLTEXT01","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:kth-4664","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4664","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":195,"referenced_works":["https://openalex.org/W212854950","https://openalex.org/W789458867","https://openalex.org/W843253719","https://openalex.org/W1492678110","https://openalex.org/W1498566120","https://openalex.org/W1502937395","https://openalex.org/W1541514857","https://openalex.org/W1543521034","https://openalex.org/W1557627802","https://openalex.org/W1575104486","https://openalex.org/W1584968660","https://openalex.org/W1618955965","https://openalex.org/W1619209825","https://openalex.org/W1621033879","https://openalex.org/W1630418041","https://openalex.org/W1642251103","https://openalex.org/W1881571321","https://openalex.org/W1964788963","https://openalex.org/W1965164377","https://openalex.org/W1965337436","https://openalex.org/W1966790730","https://openalex.org/W1969886111","https://openalex.org/W1969945122","https://openalex.org/W1969950964","https://openalex.org/W1971856698","https://openalex.org/W1973360544","https://openalex.org/W1974799810","https://openalex.org/W1974915001","https://openalex.org/W1977464049","https://openalex.org/W1979013550","https://openalex.org/W1979513602","https://openalex.org/W1979653803","https://openalex.org/W1980767945","https://openalex.org/W1982003147","https://openalex.org/W1982648837","https://openalex.org/W1983572701","https://openalex.org/W1984108094","https://openalex.org/W1984909504","https://openalex.org/W1985709800","https://openalex.org/W1989003662","https://openalex.org/W1990697206","https://openalex.org/W1991478997","https://openalex.org/W2001060611","https://openalex.org/W2003251142","https://openalex.org/W2004290556","https://openalex.org/W2005652267","https://openalex.org/W2006362531","https://openalex.org/W2007632362","https://openalex.org/W2008928010","https://openalex.org/W2009004088","https://openalex.org/W2010817790","https://openalex.org/W2011573266","https://openalex.org/W2012625632","https://openalex.org/W2012708339","https://openalex.org/W2015467993","https://openalex.org/W2017312934","https://openalex.org/W2017457274","https://openalex.org/W2019500447","https://openalex.org/W2021820673","https://openalex.org/W2022762682","https://openalex.org/W2023616637","https://openalex.org/W2024296214","https://openalex.org/W2025120795","https://openalex.org/W2026355422","https://openalex.org/W2027140414","https://openalex.org/W2028669466","https://openalex.org/W2030267692","https://openalex.org/W2030365976","https://openalex.org/W2033237792","https://openalex.org/W2033257199","https://openalex.org/W2033363708","https://openalex.org/W2033572662","https://openalex.org/W2034725792","https://openalex.org/W2035704242","https://openalex.org/W2035910211","https://openalex.org/W2036315153","https://openalex.org/W2036843133","https://openalex.org/W2040536746","https://openalex.org/W2040795998","https://openalex.org/W2040991028","https://openalex.org/W2044204709","https://openalex.org/W2045594387","https://openalex.org/W2045674411","https://openalex.org/W2049761345","https://openalex.org/W2050468767","https://openalex.org/W2051764674","https://openalex.org/W2052259224","https://openalex.org/W2052844522","https://openalex.org/W2052937897","https://openalex.org/W2053988500","https://openalex.org/W2054516780","https://openalex.org/W2055870007","https://openalex.org/W2056217914","https://openalex.org/W2057959735","https://openalex.org/W2057980421","https://openalex.org/W2058101090","https://openalex.org/W2058837813","https://openalex.org/W2060061334","https://openalex.org/W2060519194","https://openalex.org/W2061440509","https://openalex.org/W2062875344","https://openalex.org/W2063070514","https://openalex.org/W2064576738","https://openalex.org/W2064598149","https://openalex.org/W2064624057","https://openalex.org/W2065786781","https://openalex.org/W2066644069","https://openalex.org/W2066898519","https://openalex.org/W2069475791","https://openalex.org/W2069618664","https://openalex.org/W2071131107","https://openalex.org/W2073037039","https://openalex.org/W2075332282","https://openalex.org/W2075525059","https://openalex.org/W2077929353","https://openalex.org/W2082565099","https://openalex.org/W2082631326","https://openalex.org/W2083630006","https://openalex.org/W2084559690","https://openalex.org/W2084729729","https://openalex.org/W2085266415","https://openalex.org/W2085796374","https://openalex.org/W2086691890","https://openalex.org/W2086845400","https://openalex.org/W2088012076","https://openalex.org/W2088659094","https://openalex.org/W2091385392","https://openalex.org/W2092144432","https://openalex.org/W2092384270","https://openalex.org/W2093134622","https://openalex.org/W2093684161","https://openalex.org/W2094760833","https://openalex.org/W2094972510","https://openalex.org/W2095633207","https://openalex.org/W2096526911","https://openalex.org/W2097729800","https://openalex.org/W2100359971","https://openalex.org/W2102253445","https://openalex.org/W2102787760","https://openalex.org/W2104308218","https://openalex.org/W2105021118","https://openalex.org/W2110390400","https://openalex.org/W2110637662","https://openalex.org/W2111127052","https://openalex.org/W2113343496","https://openalex.org/W2113372755","https://openalex.org/W2113919194","https://openalex.org/W2114229182","https://openalex.org/W2114849571","https://openalex.org/W2116209349","https://openalex.org/W2116857926","https://openalex.org/W2121326637","https://openalex.org/W2126198460","https://openalex.org/W2129473723","https://openalex.org/W2134400489","https://openalex.org/W2134780839","https://openalex.org/W2136394253","https://openalex.org/W2137055458","https://openalex.org/W2139759409","https://openalex.org/W2140524539","https://openalex.org/W2141496833","https://openalex.org/W2142648753","https://openalex.org/W2145684136","https://openalex.org/W2145992318","https://openalex.org/W2146156928","https://openalex.org/W2147160925","https://openalex.org/W2149315921","https://openalex.org/W2151034868","https://openalex.org/W2151274733","https://openalex.org/W2152229168","https://openalex.org/W2152516404","https://openalex.org/W2152617069","https://openalex.org/W2152696833","https://openalex.org/W2154229015","https://openalex.org/W2155418451","https://openalex.org/W2156185861","https://openalex.org/W2157787219","https://openalex.org/W2157833945","https://openalex.org/W2158671383","https://openalex.org/W2159335259","https://openalex.org/W2161288621","https://openalex.org/W2161678017","https://openalex.org/W2162129355","https://openalex.org/W2165338865","https://openalex.org/W2165999429","https://openalex.org/W2167084558","https://openalex.org/W2167150894","https://openalex.org/W2170316986","https://openalex.org/W2171034039","https://openalex.org/W2171268876","https://openalex.org/W2352682556","https://openalex.org/W2386250206","https://openalex.org/W2521616874","https://openalex.org/W3104310852","https://openalex.org/W7099469271"],"related_works":["https://openalex.org/W1600371944","https://openalex.org/W2341553760","https://openalex.org/W3104502756","https://openalex.org/W3087592012","https://openalex.org/W7096485307","https://openalex.org/W4238698359","https://openalex.org/W7099889188","https://openalex.org/W2005418580","https://openalex.org/W7096531370","https://openalex.org/W2143563494"],"abstract_inverted_index":{"Motor":[0],"proteins":[1,102],"are":[2,212],"microscopic":[3],"biological":[4,21],"machines":[5],"that":[6,152,252],"convert":[7],"chemical":[8,287],"energy":[9],"into":[10],"mechanical":[11],"motion":[12,29,188],"and":[13,27,34,60,86,107,236,260],"work.":[14],"They":[15],"power":[16],"a":[17,123,141,164,190,241,249,268,283],"diverse":[18],"range":[19],"of":[20,30,41,100,114,126,172,182,189,205,234,264,282,296],"processes,":[22],"for":[23,56],"example":[24],"the":[25,38,79,104,112,146,153,159,170,173,180,186,219,226,232,279,286],"swimming":[26],"crawling":[28],"bacteria,":[31],"intracellular":[32],"transport,":[33],"muscle":[35],"contraction.":[36],"Understanding":[37],"physical":[39,98],"basis":[40],"these":[42,76],"processes":[43],"is":[44,95,193,200],"interesting":[45,54],"in":[46,58,66,92,111,184,195,203,257],"its":[47],"own":[48],"right,":[49],"but":[50],"also":[51],"has":[52],"an":[53],"potential":[55],"applications":[57],"medicine":[59],"nanotechnology.":[61],"The":[62,89],"ongoing":[63],"rapid":[64],"developments":[65],"single":[67,80,115],"molecule":[68,81,116],"experimental":[69],"techniques":[70],"make":[71],"it":[72],"possible":[73],"to":[74,133,179,215,225,255],"probe":[75],"systems":[77],"on":[78,103,169],"level,":[82],"with":[83,97,108,231,274],"increasing":[84],"temporal":[85],"spatial":[87],"resolution.":[88],"work":[90,233],"presented":[91],"this":[93,275],"thesis":[94],"concerned":[96],"modeling":[99],"motor":[101,147,191,271],"molecular":[105],"scale,":[106],"theoretical":[109],"challenges":[110],"interpretation":[113,181],"experiments.":[117],"First,":[118],"we":[119,150,176],"have":[120,177,239],"investigated":[121],"how":[122],"small":[124],"groups":[125],"elastically":[127],"coupled":[128],"motors":[129,154],"collaborate,":[130],"or":[131],"fail":[132],"do":[134,222],"so,":[135],"when":[136],"producing":[137],"strong":[138],"forces.":[139],"Using":[140],"simple":[142],"model":[143],"inspired":[144],"by":[145],"protein":[148,192],"PilT,":[149],"\ufb01nd":[151],"counteract":[155],"each":[156],"other":[157],"if":[158],"density":[160],"becomes":[161],"higher":[162],"than":[163],"certain":[165],"threshold,":[166],"which":[167,185],"depends":[168],"asymmetry":[171],"system.":[174],"Second,":[175],"contributed":[178],"experiments":[183],"stepwise":[187],"followed":[194],"real":[196],"time.":[197],"Such":[198],"data":[199,266],"naturally":[201],"interpreted":[202],"terms":[204],"\ufb01rst":[206],"passage":[207],"processes.":[208],"Our":[209],"main":[210],"conclusions":[211],"(1)":[213],"Contrary":[214],"some":[216],"earlier":[217],"suggestions,":[218],"stepping":[220,265,297],"events":[221,229],"not":[223],"correspond":[224],"cycle":[227],"completion":[228],"associated":[230],"Hill":[235],"co-workers.":[237],"We":[238],"given":[240],"correct":[242],"formulation.":[243],"(2)":[244],"Simple":[245],"kinetic":[246],"models":[247],"predict":[248],"generic":[250],"mechanism":[251],"gives":[253],"rise":[254],"correlations":[256],"step":[258],"directions":[259],"waiting":[261],"times.":[262],"Analysis":[263],"from":[267,293],"chimaeric":[269],"\ufb02agellar":[270],"was":[272],"consistent":[273],"prediction.":[276],"(3)":[277],"In":[278],"special":[280],"case":[281],"reversible":[284],"motor,":[285],"driving":[288],"force":[289],"can":[290],"be":[291],"extracted":[292],"statistical":[294],"analysis":[295],"trajectories.":[298]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}