{"id":"https://openalex.org/W2111004765","doi":"https://doi.org/10.1093/neuonc/not049","title":"Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study","display_name":"Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study","publication_year":2013,"publication_date":"2013-06-19","ids":{"openalex":"https://openalex.org/W2111004765","doi":"https://doi.org/10.1093/neuonc/not049","mag":"2111004765","pmid":"https://pubmed.ncbi.nlm.nih.gov/23788270","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3688018"},"language":"en","primary_location":{"id":"doi:10.1093/neuonc/not049","doi":"https://doi.org/10.1093/neuonc/not049","is_oa":false,"landing_page_url":"https://doi.org/10.1093/neuonc/not049","pdf_url":null,"source":{"id":"https://openalex.org/S106908163","display_name":"Neuro-Oncology","issn_l":"1522-8517","issn":["1522-8517","1523-5866"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro-Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3688018","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053277352","display_name":"J. L. Boxerman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4210151747","display_name":"Lifespan","ror":"https://ror.org/04yt1rh21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210151747"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. L. Boxerman","raw_affiliation_strings":["Rhode Island Hospital, Department of Diagnostic Imaging, 593 Eddy St., Providence, RI 02903, USA. jboxerman@lifespan.org","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rhode Island Hospital, Department of Diagnostic Imaging, 593 Eddy St., Providence, RI 02903, USA. jboxerman@lifespan.org","institution_ids":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100459176","display_name":"Zheng Zhang","orcid":"https://orcid.org/0000-0003-2497-0362","observed_orcids":["https://orcid.org/0000-0003-2497-0362"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Z. Zhang","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054908913","display_name":"Yair I. Safriel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Safriel","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090338768","display_name":"Mykol Larvie","orcid":"https://orcid.org/0000-0003-4235-3624","observed_orcids":["https://orcid.org/0000-0003-4235-3624"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Larvie","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002816178","display_name":"Bradley S. Snyder","orcid":"https://orcid.org/0000-0003-2757-7195","observed_orcids":["https://orcid.org/0000-0003-2757-7195"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. S. Snyder","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005492660","display_name":"Rajan Jain","orcid":"https://orcid.org/0000-0002-4879-0457","observed_orcids":["https://orcid.org/0000-0002-4879-0457"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Jain","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. L. Chi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. L. Chi","raw_affiliation_strings":["A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038428624","display_name":"Alma Gregory Sorensen","orcid":"https://orcid.org/0000-0001-7750-8206","observed_orcids":["https://orcid.org/0000-0001-7750-8206"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. G. Sorensen","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064627876","display_name":"Mark R. Gilbert","orcid":"https://orcid.org/0000-0003-2556-9722","observed_orcids":["https://orcid.org/0000-0003-2556-9722"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. R. Gilbert","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011760069","display_name":"Daniel P. Barboriak","orcid":"https://orcid.org/0000-0002-2536-6266","observed_orcids":["https://orcid.org/0000-0002-2536-6266"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. P. Barboriak","raw_affiliation_strings":["Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.); Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater, Florida (Y.S.); Department of Radiology, Massachusetts General Hospital, Boston, M assachusetts (M.L.); Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, M ichigan (R.J.); Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, T exas (L.C.); A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, M assachusetts (A.G.S.); Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, T exas (M.R.G.); Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts (A.G.S.)","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Diagnostic Imaging, Rhode Island Hospital and Alpert Medical School of Brown University, (J.L.B.), and Center for Statistical Sciences, Brown University, Providence, Rhode Island (Z.Z., B.S.S.)","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (L.C.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (M.R.G.)","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, North Carolina (D.P.B.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts (M.L.)","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Departments of Radiology and Neurosurgery, Henry Ford Hospital, Detroit, Michigan (R.J.)","institution_ids":["https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Pharmascan Clinical Trials and Radiology Associates of Clearwater\u2013University of South Florida, Clearwater,Florida (Y.S.)","institution_ids":["https://openalex.org/I2613432"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5053277352"],"corresponding_institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I2613432","https://openalex.org/I27804330","https://openalex.org/I2800446032","https://openalex.org/I2803043754","https://openalex.org/I4210087915","https://openalex.org/I4210126298","https://openalex.org/I4210127055","https://openalex.org/I4210151747"],"apc_list":{"value":5132,"currency":"USD","value_usd":5132},"apc_paid":null,"fwci":3.6389,"has_fulltext":false,"cited_by_count":79,"citation_normalized_percentile":{"value":0.93971234,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"15","issue":"7","first_page":"945","last_page":"954"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/recurrent-glioblastoma","display_name":"recurrent glioblastoma","score":0.9900000095367432},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.996999979019165},{"id":"https://openalex.org/keywords/radiographic-progression","display_name":"radiographic progression","score":0.6800000071525574},{"id":"https://openalex.org/keywords/contrast-enhanced-mri","display_name":"contrast-enhanced MRI","score":0.7039999961853027},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7269999980926514},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9929999709129333},{"id":"https://openalex.org/keywords/flair-hyperintensity","display_name":"FLAIR hyperintensity","score":0.753000020980835},{"id":"https://openalex.org/keywords/temozolomide","display_name":"temozolomide","score":0.8009999990463257},{"id":"https://openalex.org/keywords/irinotecan","display_name":"irinotecan","score":0.9909999966621399},{"id":"https://openalex.org/keywords/macdonald-criteria","display_name":"Macdonald criteria","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8964895009994507},{"id":"https://openalex.org/C2777802072","wikidata":"https://www.wikidata.org/wiki/Q413299","display_name":"Bevacizumab","level":3,"score":0.8136004209518433},{"id":"https://openalex.org/C101070640","wikidata":"https://www.wikidata.org/wiki/Q3737215","display_name":"Fluid-attenuated inversion recovery","level":3,"score":0.7876553535461426},{"id":"https://openalex.org/C2777389519","wikidata":"https://www.wikidata.org/wiki/Q425088","display_name":"Temozolomide","level":3,"score":0.7441610097885132},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5539485812187195},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.5113739371299744},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.49152740836143494},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.4797162413597107},{"id":"https://openalex.org/C2780739268","wikidata":"https://www.wikidata.org/wiki/Q2112244","display_name":"Progression-free survival","level":3,"score":0.4746188223361969},{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.4198693037033081},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.39838337898254395},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3448488414287567},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3310006260871887},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.30802661180496216},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.30152109265327454},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.28498780727386475},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.13575652241706848}],"mesh":[{"descriptor_ui":"D000068258","descriptor_name":"Bevacizumab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077146","descriptor_name":"Irinotecan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077204","descriptor_name":"Temozolomide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D002166","descriptor_name":"Camptothecin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002166","descriptor_name":"Camptothecin","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003606","descriptor_name":"Dacarbazine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003606","descriptor_name":"Dacarbazine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/neuonc/not049","doi":"https://doi.org/10.1093/neuonc/not049","is_oa":false,"landing_page_url":"https://doi.org/10.1093/neuonc/not049","pdf_url":null,"source":{"id":"https://openalex.org/S106908163","display_name":"Neuro-Oncology","issn_l":"1522-8517","issn":["1522-8517","1523-5866"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro-Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3688018","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3688018","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro Oncol","raw_type":"Text"},{"id":"pmid:23788270","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23788270","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro-oncology","raw_type":"Clinical Trial, Phase II"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.939.1366","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.939.1366","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://neuro-oncology.oxfordjournals.org/content/early/2013/06/19/neuonc.not049.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.947.8386","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.947.8386","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://neuro-oncology.oxfordjournals.org/content/15/7/945.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3688018","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3688018","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuro Oncol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1045868681","display_name":"Biostatistics Data Management Center for ACRIN","funder_award_id":"U01CA079778","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4103882781","display_name":"American College of Radiology Imaging Network","funder_award_id":"U01CA080098","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309042","display_name":"American College of Radiology Imaging Network","ror":"https://ror.org/01cywgd53"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1959628099","https://openalex.org/W1968287404","https://openalex.org/W1968703754","https://openalex.org/W1968897934","https://openalex.org/W1976975280","https://openalex.org/W1979368207","https://openalex.org/W1982108459","https://openalex.org/W1982157452","https://openalex.org/W1992812368","https://openalex.org/W2001244599","https://openalex.org/W2002727873","https://openalex.org/W2007131804","https://openalex.org/W2012255417","https://openalex.org/W2040260938","https://openalex.org/W2042692181","https://openalex.org/W2045538453","https://openalex.org/W2056829262","https://openalex.org/W2058521348","https://openalex.org/W2059944898","https://openalex.org/W2078646447","https://openalex.org/W2080951960","https://openalex.org/W2084495605","https://openalex.org/W2089764574","https://openalex.org/W2092736872","https://openalex.org/W2093084676","https://openalex.org/W2093783077","https://openalex.org/W2096287682","https://openalex.org/W2102488910","https://openalex.org/W2104032744","https://openalex.org/W2108090165","https://openalex.org/W2108151310","https://openalex.org/W2112014411","https://openalex.org/W2114711939","https://openalex.org/W2116891323","https://openalex.org/W2118311655","https://openalex.org/W2127745545","https://openalex.org/W2132697290","https://openalex.org/W2137261274","https://openalex.org/W2137832651","https://openalex.org/W2137999403","https://openalex.org/W2140201170","https://openalex.org/W2142104626","https://openalex.org/W2142312148","https://openalex.org/W2148233336","https://openalex.org/W2151133505","https://openalex.org/W2158681922","https://openalex.org/W2160494869","https://openalex.org/W2162293072","https://openalex.org/W2162643152","https://openalex.org/W2163458899","https://openalex.org/W2169424184","https://openalex.org/W2375878541"],"related_works":["https://openalex.org/W7099303119","https://openalex.org/W2792671843","https://openalex.org/W2159382304","https://openalex.org/W2725326012","https://openalex.org/W2137261274","https://openalex.org/W4318046603","https://openalex.org/W2076269412","https://openalex.org/W2904651700","https://openalex.org/W2089038482","https://openalex.org/W2603876887"],"abstract_inverted_index":{"BACKGROUND:":[0],"RTOG":[1],"0625/ACRIN":[2],"6677":[3],"is":[4],"a":[5,91],"multicenter,":[6],"randomized,":[7],"phase":[8],"II":[9],"trial":[10],"of":[11,72,96,137,141,146,157,161,166,266],"bevacizumab":[12],"with":[13,90,120],"irinotecan":[14],"or":[15,30,121,183],"temozolomide":[16],"in":[17,135,279],"recurrent":[18,280],"glioblastoma":[19],"(GBM).":[20],"This":[21],"study":[22],"investigated":[23],"whether":[24],"early":[25],"posttreatment":[26,53,79],"progression":[27,98,127,252],"on":[28,66,77,195,232,253],"FLAIR":[29,73,152,233,259],"postcontrast":[31,67],"MRI":[32,104],"assessed":[33],"by":[34],"central":[35,56],"reading":[36],"predicts":[37],"overall":[38],"survival":[39,108],"(OS).":[40],"METHODS:":[41],"Of":[42],"123":[43],"enrolled":[44],"patients,":[45],"107":[46],"had":[47],"baseline":[48],"and":[49,62,70,85,100,110,144,151,155,164,201,212,221,241,255,263],"at":[50,181],"least":[51],"1":[52],"MRI.":[54],"Two":[55],"neuroradiologists":[57],"serially":[58],"measured":[59],"bidimensional":[60],"(2D)":[61],"volumetric":[63],"(3D)":[64],"enhancement":[65],"T1-weighted":[68],"images":[69],"volume":[71],"hyperintensity.":[74],"Progression":[75],"status":[76],"all":[78],"MRIs":[80],"was":[81,186],"determined":[82,194],"using":[83],"Macdonald":[84],"RANO":[86],"imaging":[87],"threshold":[88],"criteria,":[89],"third":[92],"neuroradiologist":[93],"adjudicating":[94],"discrepancies":[95],"both":[97],"occurrence":[99],"timing.":[101],"For":[102],"each":[103],"pulse":[105],"sequence,":[106],"Kaplan-Meier":[107],"estimates":[109],"log-rank":[111],"test":[112],"were":[113],"used":[114],"to":[115],"compare":[116],"OS":[117,177,278],"between":[118],"cases":[119,170],"without":[122],"radiologic":[123],"progression.":[124],"RESULTS:":[125],"Radiologic":[126],"occurred":[128],"after":[129,171,261],"2":[130],"chemotherapy":[131],"cycles":[132,173],"(8":[133],"weeks)":[134],"9":[136,140],"97":[138],"(9%),":[139],"73":[142],"(12%),":[143],"11":[145],"98":[147],"(11%)":[148],"2D-T1,":[149],"3D-T1,":[150,256],"cases,":[153],"respectively,":[154],"34":[156],"80":[158],"(43%),":[159],"21":[160],"58":[162],"(36%),":[163],"37":[165],"79":[167],"(47%)":[168],"corresponding":[169],"4":[172],"(16":[174],"weeks).":[175],"Median":[176],"among":[178,191],"patients":[179],"progressing":[180],"8":[182,262],"16":[184,264],"weeks":[185,265],"significantly":[187],"less":[188],"than":[189],"that":[190],"nonprogressors,":[192],"as":[193],"2D-T1":[196,254],"(114":[197],"vs":[198,203,215,223,235,243],"278":[199],"days":[200,217,225,237,245],"214":[202],"426":[204],"days,":[205],"respectively;":[206],"P":[207],"<":[208,219],".0001":[209],"for":[210,277],"both)":[211],"3D-T1":[213],"(117":[214],"306":[216],"[P":[218,226,238,246],".0001]":[220],"223":[222],"448":[224],"=":[227,239,247],".0003],":[228],"respectively)":[229],"but":[230,257],"not":[231,258],"(201":[234],"276":[236],".38]":[240],"303":[242],"321":[244],".13],":[248],"respectively).":[249],"CONCLUSION:":[250],"Early":[251],"MRI,":[260],"anti-vascular":[267],"endothelial":[268],"growth":[269],"factor":[270],"therapy":[271],"has":[272],"highly":[273],"significant":[274],"prognostic":[275],"value":[276],"GBM.":[281]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}