{"id":"https://openalex.org/W2110151622","doi":"https://doi.org/10.1073/pnas.0509457102","title":"The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney","display_name":"The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney","publication_year":2005,"publication_date":"2005-12-12","ids":{"openalex":"https://openalex.org/W2110151622","doi":"https://doi.org/10.1073/pnas.0509457102","mag":"2110151622","pmid":"https://pubmed.ncbi.nlm.nih.gov/16344459","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1311743"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.0509457102","doi":"https://doi.org/10.1073/pnas.0509457102","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0509457102","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC1311743","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022001789","display_name":"Sung\u2010Kook Hong","orcid":"https://orcid.org/0000-0002-6546-096X","observed_orcids":["https://orcid.org/0000-0002-6546-096X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sung-Kook Hong","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I170201317","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003796458","display_name":"Caroline E. Haldin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caroline E. Haldin","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I170201317","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055322887","display_name":"Nathan D. Lawson","orcid":"https://orcid.org/0000-0001-7788-9619","observed_orcids":["https://orcid.org/0000-0001-7788-9619"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan D. Lawson","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I170201317","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039020080","display_name":"Brant M. Weinstein","orcid":"https://orcid.org/0000-0003-4136-4962","observed_orcids":["https://orcid.org/0000-0003-4136-4962"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brant M. Weinstein","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I170201317","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064390918","display_name":"Igor B. Dawid","orcid":"https://orcid.org/0000-0003-0579-5693","observed_orcids":["https://orcid.org/0000-0003-0579-5693"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Igor B. Dawid","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I170201317","https://openalex.org/I4210144228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038463777","display_name":"Neil A. Hukriede","orcid":"https://orcid.org/0000-0002-9655-9030","observed_orcids":["https://orcid.org/0000-0002-9655-9030"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil A. Hukriede","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, W1152 BSTWR, Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I170201317","https://openalex.org/I4210144228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.6352,"has_fulltext":false,"cited_by_count":81,"citation_normalized_percentile":{"value":0.8978751,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"102","issue":"51","first_page":"18473","last_page":"18478"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.8457000255584717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.8457000255584717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.15299999713897705,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mediator-complex","display_name":"Mediator complex","score":0.8119999766349792},{"id":"https://openalex.org/keywords/zebrafish-embryonic-development","display_name":"zebrafish embryonic development","score":0.7850000262260437},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.9750000238418579},{"id":"https://openalex.org/keywords/neural-crest-development","display_name":"neural crest development","score":0.9459999799728394},{"id":"https://openalex.org/keywords/morphogenesis","display_name":"morphogenesis","score":0.8199999928474426},{"id":"https://openalex.org/keywords/cell-mobility","display_name":"cell mobility","score":0.7730000019073486},{"id":"https://openalex.org/keywords/cell-sorting","display_name":"cell sorting","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.82215416431427},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8110121488571167},{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.7625195980072021},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.5962138772010803},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5960228443145752},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5579840540885925},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.5406607389450073},{"id":"https://openalex.org/C197849852","wikidata":"https://www.wikidata.org/wiki/Q2314823","display_name":"Neural plate","level":4,"score":0.5028666853904724},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.48270606994628906},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4404568076133728}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005136","descriptor_name":"Eye Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005136","descriptor_name":"Eye Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D056892","descriptor_name":"Mediator Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.0509457102","doi":"https://doi.org/10.1073/pnas.0509457102","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0509457102","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:264923","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1311743","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1311743","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1311743","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:16344459","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16344459","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:264923","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1311743","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W102944501","https://openalex.org/W1718193936","https://openalex.org/W1831514224","https://openalex.org/W1834486239","https://openalex.org/W1969376923","https://openalex.org/W1970292137","https://openalex.org/W1982161126","https://openalex.org/W1985721503","https://openalex.org/W1988690189","https://openalex.org/W1988893861","https://openalex.org/W1990125829","https://openalex.org/W2004553881","https://openalex.org/W2009296444","https://openalex.org/W2012248317","https://openalex.org/W2022281569","https://openalex.org/W2029099543","https://openalex.org/W2032349328","https://openalex.org/W2032689526","https://openalex.org/W2033289754","https://openalex.org/W2036894680","https://openalex.org/W2044756723","https://openalex.org/W2046518261","https://openalex.org/W2052251250","https://openalex.org/W2056635197","https://openalex.org/W2058325289","https://openalex.org/W2066092773","https://openalex.org/W2067285199","https://openalex.org/W2073606372","https://openalex.org/W2073960425","https://openalex.org/W2076997608","https://openalex.org/W2091760375","https://openalex.org/W2095422595","https://openalex.org/W2097214643","https://openalex.org/W2099791270","https://openalex.org/W2108053584","https://openalex.org/W2108274213","https://openalex.org/W2132845755","https://openalex.org/W2136526854","https://openalex.org/W2137161806","https://openalex.org/W2140992277","https://openalex.org/W2146445411","https://openalex.org/W2146650331","https://openalex.org/W2150126479","https://openalex.org/W2151637834","https://openalex.org/W2151849975","https://openalex.org/W2153649171","https://openalex.org/W2156952955","https://openalex.org/W2159894317","https://openalex.org/W2164705615","https://openalex.org/W2188108992"],"related_works":["https://openalex.org/W2090090763","https://openalex.org/W2565478622","https://openalex.org/W4200624881","https://openalex.org/W2170712488","https://openalex.org/W7024987372","https://openalex.org/W4294591817","https://openalex.org/W7097592385","https://openalex.org/W2024929712","https://openalex.org/W4206268316","https://openalex.org/W2461650427"],"abstract_inverted_index":{"Mutation":[0],"of":[1,16,85,98],"the":[2,5,14,28,35,40,67],"gene":[3,29],"encoding":[4,30],"Mediator":[6],"component":[7],"thyroid":[8],"hormone":[9],"receptor-associated":[10],"protein":[11,32],"(TRAP)230/MED12":[12],"affects":[13],"development":[15,58],"multiple":[17],"systems":[18],"in":[19,27,43,52],"zebrafish":[20,48],"embryogenesis.":[21],"We":[22],"isolated":[23],"two":[24],"ethylnitrosourea-induced":[25],"alleles":[26],"this":[31],"and":[33,56,59,73,87,110],"named":[34],"locus":[36,42],"kohtalo":[37],"(kto)":[38],"after":[39],"homologous":[41],"Drosophila.":[44],"Homozygous":[45],"kto":[46],"mutant":[47],"embryos":[49],"show":[50],"defects":[51],"brain,":[53],"neural":[54],"crest,":[55],"kidney":[57],"die":[60],"at":[61],"approximately":[62],"6":[63],"days":[64],"postfertilization.":[65],"In":[66],"affected":[68],"tissues,":[69],"differentiation":[70],"is":[71,82],"initiated":[72],"many":[74],"cell":[75,106,108],"type-specific":[76],"genes":[77],"are":[78],"expressed,":[79],"but":[80],"there":[81],"a":[83],"failure":[84,88],"morphogenesis":[86],"to":[89],"complete":[90],"differentiation.":[91],"These":[92],"results":[93],"suggest":[94],"that":[95],"critical":[96],"targets":[97],"TRAP230":[99],"function":[100],"may":[101],"include":[102],"proteins":[103],"important":[104],"for":[105],"mobility,":[107],"sorting,":[109],"tissue":[111],"assembly.":[112]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
