{"id":"https://openalex.org/W2110058049","doi":"https://doi.org/10.3389/fimmu.2014.00647","title":"Dendritic Cells in Dengue Virus Infection: Targets of Virus Replication and Mediators of Immunity","display_name":"Dendritic Cells in Dengue Virus Infection: Targets of Virus Replication and Mediators of Immunity","publication_year":2014,"publication_date":"2014-12-17","ids":{"openalex":"https://openalex.org/W2110058049","doi":"https://doi.org/10.3389/fimmu.2014.00647","mag":"2110058049","pmid":"https://pubmed.ncbi.nlm.nih.gov/25566258","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4269190"},"language":"en","primary_location":{"id":"doi:10.3389/fimmu.2014.00647","doi":"https://doi.org/10.3389/fimmu.2014.00647","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2014.00647","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2014.00647/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2014.00647/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015786500","display_name":"Michael Schmid","orcid":"https://orcid.org/0000-0002-1137-9322","observed_orcids":["https://orcid.org/0000-0002-1137-9322"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael A. Schmid","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070153307","display_name":"Michael Diamond","orcid":"https://orcid.org/0000-0002-8791-3165","observed_orcids":["https://orcid.org/0000-0002-8791-3165"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael S. Diamond","raw_affiliation_strings":["Department of Medicine, Washington University School of Medicine , St. Louis, MO , USA ; Department of Molecular Microbiology, Washington University School of Medicine , St. Louis, MO , USA ; Department of Pathology and Immunology, Washington University School of Medicine , St. Louis, MO , USA","Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA","Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA","Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Washington University School of Medicine , St. Louis, MO , USA ; Department of Molecular Microbiology, Washington University School of Medicine , St. Louis, MO , USA ; Department of Pathology and Immunology, Washington University School of Medicine , St. Louis, MO , USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027442064","display_name":"Eva Harris","orcid":"https://orcid.org/0000-0002-7238-4037","observed_orcids":["https://orcid.org/0000-0002-7238-4037"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eva Harris","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015786500","https://openalex.org/A5027442064"],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":1.893,"has_fulltext":true,"cited_by_count":135,"citation_normalized_percentile":{"value":0.86106811,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"5","issue":null,"first_page":"647","last_page":"647"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dengue-virus","display_name":"dengue virus","score":0.9629999995231628},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.699999988079071},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9990000128746033},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.9200000166893005},{"id":"https://openalex.org/keywords/adaptive-immunity","display_name":"adaptive immunity","score":0.9020000100135803},{"id":"https://openalex.org/keywords/t-cell-response","display_name":"T cell response","score":0.5419999957084656},{"id":"https://openalex.org/keywords/b-cell-response","display_name":"B cell response","score":0.9190000295639038},{"id":"https://openalex.org/keywords/secondary-dengue-infection","display_name":"secondary dengue infection","score":0.7480000257492065},{"id":"https://openalex.org/keywords/antibody-enhancement","display_name":"antibody enhancement","score":0.5270000100135803},{"id":"https://openalex.org/keywords/cross-reactive-t-cells","display_name":"cross-reactive T cells","score":0.8500000238418579},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.8510000109672546},{"id":"https://openalex.org/keywords/memory-b-cells","display_name":"memory B cells","score":0.6430000066757202},{"id":"https://openalex.org/keywords/memory-t-cells","display_name":"memory T cells","score":0.7480000257492065},{"id":"https://openalex.org/keywords/aedes-aegypti","display_name":"Aedes aegypti","score":0.8100000023841858},{"id":"https://openalex.org/keywords/aedes-albopictus","display_name":"Aedes albopictus","score":0.8299999833106995},{"id":"https://openalex.org/keywords/arbovirus-infection","display_name":"arbovirus infection","score":0.734000027179718}],"concepts":[{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7798410654067993},{"id":"https://openalex.org/C2779635636","wikidata":"https://www.wikidata.org/wiki/Q476209","display_name":"Dengue virus","level":3,"score":0.7491544485092163},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6246538162231445},{"id":"https://openalex.org/C196594336","wikidata":"https://www.wikidata.org/wiki/Q1662341","display_name":"Antibody-dependent enhancement","level":4,"score":0.6212130784988403},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6169006824493408},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49136605858802795},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.4613158702850342},{"id":"https://openalex.org/C12590798","wikidata":"https://www.wikidata.org/wiki/Q3933199","display_name":"Replication (statistics)","level":2,"score":0.4608106315135956},{"id":"https://openalex.org/C533803919","wikidata":"https://www.wikidata.org/wiki/Q30953","display_name":"Dengue fever","level":2,"score":0.438725084066391},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4177107512950897},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3066839873790741}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/fimmu.2014.00647","doi":"https://doi.org/10.3389/fimmu.2014.00647","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2014.00647","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2014.00647/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3254650","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4269190","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4269190","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4269190","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Immunol","raw_type":"Text"},{"id":"pmid:25566258","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25566258","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in immunology","raw_type":"Journal Article"},{"id":"pmh:oai:digitalcommons.wustl.edu:open_access_pubs-4624","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.wustl.edu/open_access_pubs/3621","pdf_url":"https://digitalcommons.wustl.edu/open_access_pubs/3621","source":{"id":"https://openalex.org/S4306400764","display_name":"Digital Commons@Becker (Washington University School of Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204465549","host_organization_name":"Washington University in St. Louis","host_organization_lineage":["https://openalex.org/I204465549"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Open Access Publications","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:31ea8b75751240d08321eed4b420b483","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/31ea8b75751240d08321eed4b420b483","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Immunology, Vol 5 (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fimmu.2014.00647","doi":"https://doi.org/10.3389/fimmu.2014.00647","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2014.00647","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2014.00647/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G255162286","display_name":null,"funder_award_id":"R01 AI077955","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4388001361","display_name":"Safe Antibody Prophylaxis and Therapy Against Dengue Virus","funder_award_id":"U01AI077955","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6078043664","display_name":"Determinants of protection and enhancement of dengue infection/disease in vivo","funder_award_id":"R01AI085607","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8102765400","display_name":null,"funder_award_id":"AI077955","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8276362926","display_name":null,"funder_award_id":"SCHM 3011/1-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2110058049.pdf","grobid_xml":"https://content.openalex.org/works/W2110058049.grobid-xml"},"referenced_works_count":128,"referenced_works":["https://openalex.org/W1494401243","https://openalex.org/W1494483012","https://openalex.org/W1502104604","https://openalex.org/W1630111658","https://openalex.org/W1785302422","https://openalex.org/W1928251300","https://openalex.org/W1964953975","https://openalex.org/W1966837270","https://openalex.org/W1968292598","https://openalex.org/W1970926254","https://openalex.org/W1972492922","https://openalex.org/W1973587186","https://openalex.org/W1973898630","https://openalex.org/W1976351328","https://openalex.org/W1979481132","https://openalex.org/W1987481383","https://openalex.org/W1987580985","https://openalex.org/W1989552966","https://openalex.org/W1991647854","https://openalex.org/W1992873880","https://openalex.org/W1997337311","https://openalex.org/W2003828813","https://openalex.org/W2005286637","https://openalex.org/W2005754279","https://openalex.org/W2006447162","https://openalex.org/W2008969599","https://openalex.org/W2010585539","https://openalex.org/W2012156061","https://openalex.org/W2012311836","https://openalex.org/W2017226666","https://openalex.org/W2017266174","https://openalex.org/W2017270296","https://openalex.org/W2024354504","https://openalex.org/W2033702349","https://openalex.org/W2038554008","https://openalex.org/W2040944858","https://openalex.org/W2041414165","https://openalex.org/W2042433863","https://openalex.org/W2044446613","https://openalex.org/W2045121415","https://openalex.org/W2049898530","https://openalex.org/W2051298245","https://openalex.org/W2051731494","https://openalex.org/W2051905808","https://openalex.org/W2051960468","https://openalex.org/W2053490656","https://openalex.org/W2055383445","https://openalex.org/W2056628849","https://openalex.org/W2058833815","https://openalex.org/W2059095830","https://openalex.org/W2061134744","https://openalex.org/W2062623649","https://openalex.org/W2066167790","https://openalex.org/W2068430855","https://openalex.org/W2069891242","https://openalex.org/W2071225095","https://openalex.org/W2074951994","https://openalex.org/W2081020320","https://openalex.org/W2083872083","https://openalex.org/W2085099489","https://openalex.org/W2086216487","https://openalex.org/W2086542713","https://openalex.org/W2087166273","https://openalex.org/W2090973041","https://openalex.org/W2091064323","https://openalex.org/W2091174118","https://openalex.org/W2099973274","https://openalex.org/W2100820895","https://openalex.org/W2104609729","https://openalex.org/W2105870506","https://openalex.org/W2107640934","https://openalex.org/W2109204917","https://openalex.org/W2110628545","https://openalex.org/W2110892664","https://openalex.org/W2113593295","https://openalex.org/W2114465153","https://openalex.org/W2117053011","https://openalex.org/W2117545797","https://openalex.org/W2117613022","https://openalex.org/W2118830863","https://openalex.org/W2120446258","https://openalex.org/W2121585949","https://openalex.org/W2121780828","https://openalex.org/W2121934903","https://openalex.org/W2122228966","https://openalex.org/W2122272163","https://openalex.org/W2122330521","https://openalex.org/W2124103760","https://openalex.org/W2124276742","https://openalex.org/W2125504449","https://openalex.org/W2127726515","https://openalex.org/W2127896903","https://openalex.org/W2128958227","https://openalex.org/W2131222241","https://openalex.org/W2131289385","https://openalex.org/W2131761283","https://openalex.org/W2133936786","https://openalex.org/W2134392597","https://openalex.org/W2134717733","https://openalex.org/W2137655133","https://openalex.org/W2138651252","https://openalex.org/W2145533822","https://openalex.org/W2146980643","https://openalex.org/W2149682742","https://openalex.org/W2150244847","https://openalex.org/W2151252156","https://openalex.org/W2151680934","https://openalex.org/W2152678942","https://openalex.org/W2155467132","https://openalex.org/W2155480356","https://openalex.org/W2155720484","https://openalex.org/W2156013098","https://openalex.org/W2156887984","https://openalex.org/W2160633018","https://openalex.org/W2160653307","https://openalex.org/W2160928682","https://openalex.org/W2161268300","https://openalex.org/W2163237938","https://openalex.org/W2164722422","https://openalex.org/W2166676682","https://openalex.org/W2167778863","https://openalex.org/W2168028214","https://openalex.org/W2179453167","https://openalex.org/W2270084191","https://openalex.org/W2291951660","https://openalex.org/W2411528578","https://openalex.org/W4211248568","https://openalex.org/W6696587757"],"related_works":["https://openalex.org/W2461124085","https://openalex.org/W1991715404","https://openalex.org/W1986947717","https://openalex.org/W2911741918","https://openalex.org/W2345213260","https://openalex.org/W1979102632","https://openalex.org/W2110892664","https://openalex.org/W6948069478","https://openalex.org/W2008018896","https://openalex.org/W1992873880"],"abstract_inverted_index":{"Dendritic":[0],"cells":[1],"(DCs)":[2],"are":[3],"sentinels":[4],"of":[5,14,25,144,154,159,164,179],"the":[6,18,23,61,76,80,108,151,177],"immune":[7,34,171],"system":[8],"and":[9,42,47,138,147,162,166,169,199,202,213],"detect":[10],"pathogens":[11],"at":[12],"sites":[13],"entry,":[15],"such":[16],"as":[17,156],"skin.":[19,77],"In":[20],"addition":[21],"to":[22,27,38,67,121],"ability":[24],"DCs":[26,36,155,185],"control":[28],"infections":[29],"directly":[30],"via":[31,125],"their":[32],"innate":[33,165],"functions,":[35],"help":[37,208],"prime":[39],"adaptive":[40,167],"B-":[41,198],"T-cell":[43,200],"responses":[44,212],"by":[45],"processing":[46],"presenting":[48],"antigen":[49],"in":[50,75,86,136,190],"lymphoid":[51],"tissues.":[52],"Infected":[53],"Aedes":[54,57],"aegypti":[55],"or":[56,91,128,194],"albopictus":[58],"mosquitoes":[59],"transmit":[60],"four":[62],"dengue":[63,215],"virus":[64],"(DENV)":[65],"serotypes":[66],"humans":[68,137],"while":[69],"probing":[70],"for":[71],"small":[72],"blood":[73],"vessels":[74],"DENV":[78,99,110,117,142,160,175],"causes":[79],"most":[81],"prevalent":[82],"arthropod-borne":[83],"viral":[84],"disease":[85,123],"humans,":[87],"yet":[88],"no":[89],"vaccine":[90],"specific":[92],"therapeutic":[93],"is":[94],"currently":[95],"licensed.":[96],"Although":[97],"primary":[98],"infection":[100,113,143],"confers":[101],"life-long":[102],"protective":[103,210],"immunity":[104],"against":[105],"re-infection":[106],"with":[107,114],"same":[109],"serotype,":[111],"secondary":[112],"a":[115,187],"different":[116],"serotype":[118],"can":[119],"lead":[120],"increased":[122],"severity":[124],"cross-reactive":[126],"T-cells":[127],"enhancing":[129],"antibodies.":[130],"This":[131],"review":[132],"summarizes":[133],"recent":[134],"findings":[135],"animal":[139],"models":[140],"about":[141],"DCs,":[145],"monocytes,":[146],"macrophages.":[148],"We":[149,182],"discuss":[150],"dual":[152],"role":[153,189],"both":[157],"targets":[158],"replication":[161],"mediators":[163],"immunity,":[168],"summarize":[170],"evasion":[172],"strategies":[173],"whereby":[174],"impairs":[176],"function":[178],"infected":[180],"DCs.":[181],"suggest":[183],"that":[184,203],"play":[186],"key":[188],"priming":[191],"DENV-specific":[192],"neutralizing":[193],"potentially":[195],"harmful":[196],"memory":[197,211],"responses,":[201],"future":[204],"DC-directed":[205],"therapies":[206],"may":[207],"induce":[209],"reduce":[214],"pathogenesis.":[216]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":18},{"year":2015,"cited_by_count":6}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}