{"id":"https://openalex.org/W2109964422","doi":"https://doi.org/10.1152/ajprenal.00304.2011","title":"Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC)","display_name":"Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC)","publication_year":2011,"publication_date":"2011-12-02","ids":{"openalex":"https://openalex.org/W2109964422","doi":"https://doi.org/10.1152/ajprenal.00304.2011","mag":"2109964422","pmid":"https://pubmed.ncbi.nlm.nih.gov/22129970","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3353647"},"language":"en","primary_location":{"id":"doi:10.1152/ajprenal.00304.2011","doi":"https://doi.org/10.1152/ajprenal.00304.2011","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajprenal.00304.2011","pdf_url":null,"source":{"id":"https://openalex.org/S200780590","display_name":"American Journal of Physiology-Renal Physiology","issn_l":"1522-1466","issn":["1522-1466","1931-857X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Renal Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3353647","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009276350","display_name":"Michael Bruce Butterworth","orcid":"https://orcid.org/0000-0002-2173-8333","observed_orcids":["https://orcid.org/0000-0002-2173-8333"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Michael B. Butterworth","raw_affiliation_strings":["Department of Cell Biology and Physiology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Physiology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028859014","display_name":"Robert S. Edinger","orcid":"https://orcid.org/0000-0002-3301-4762","observed_orcids":["https://orcid.org/0000-0002-3301-4762"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert S. Edinger","raw_affiliation_strings":["Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030035753","display_name":"Mark R. Silvis","orcid":"https://orcid.org/0000-0002-0717-1983","observed_orcids":["https://orcid.org/0000-0002-0717-1983"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark R. Silvis","raw_affiliation_strings":["Department of Cell Biology and Physiology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Physiology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036402423","display_name":"Luciana I. Gallo","orcid":"https://orcid.org/0000-0001-7050-0121","observed_orcids":["https://orcid.org/0000-0001-7050-0121"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luciana I. Gallo","raw_affiliation_strings":["Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021513239","display_name":"Xiubin Liang","orcid":"https://orcid.org/0000-0001-9169-0390","observed_orcids":["https://orcid.org/0000-0001-9169-0390"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiubin Liang","raw_affiliation_strings":["Department of Cell Biology and Physiology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Physiology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084438326","display_name":"Gerard L. Apodaca","orcid":"https://orcid.org/0000-0002-2432-4435","observed_orcids":["https://orcid.org/0000-0002-2432-4435"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerard Apodaca","raw_affiliation_strings":["Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010907057","display_name":"Raymond A. Fizzell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raymond A. Fizzell","raw_affiliation_strings":["Department of Cell Biology and Physiology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Physiology and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113355842","display_name":"John P. Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John P. Johnson","raw_affiliation_strings":["Department of Cell Biology and Physiology and","Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Physiology and","institution_ids":[]},{"raw_affiliation_string":"Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009276350"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9289,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.84088724,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"302","issue":"5","first_page":"F581","last_page":"F590"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.5273000001907349,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.5273000001907349,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.4699999988079071,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rab11b","display_name":"Rab11b","score":0.9929999709129333},{"id":"https://openalex.org/keywords/rab11a","display_name":"Rab11a","score":0.996999979019165},{"id":"https://openalex.org/keywords/enac","display_name":"epithelial sodium channel","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cortical-collecting-duct","display_name":"cortical collecting duct","score":0.6010000109672546},{"id":"https://openalex.org/keywords/principal-cells","display_name":"principal cells","score":0.9359999895095825},{"id":"https://openalex.org/keywords/membrane-trafficking","display_name":"membrane trafficking","score":0.6489999890327454},{"id":"https://openalex.org/keywords/endosomes","display_name":"endosomes","score":0.5709999799728394},{"id":"https://openalex.org/keywords/recycling","display_name":"recycling","score":0.4259999990463257},{"id":"https://openalex.org/keywords/sodium-transport","display_name":"sodium transport","score":0.7590000033378601},{"id":"https://openalex.org/keywords/camp-signaling","display_name":"cAMP signaling","score":0.847000002861023},{"id":"https://openalex.org/keywords/mpkccd-cells","display_name":"mpkCCD cells","score":0.7649999856948853},{"id":"https://openalex.org/keywords/small-gtpases","display_name":"small GTPases","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C6507245","wikidata":"https://www.wikidata.org/wiki/Q424948","display_name":"Epithelial sodium channel","level":3,"score":0.7875587940216064},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7591403126716614},{"id":"https://openalex.org/C156728348","wikidata":"https://www.wikidata.org/wiki/Q416778","display_name":"Rab","level":3,"score":0.7450753450393677},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.5817985534667969},{"id":"https://openalex.org/C2780298669","wikidata":"https://www.wikidata.org/wiki/Q415071","display_name":"Small GTPase","level":3,"score":0.5520294308662415},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.5156711339950562},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.4198811650276184},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41603347659111023},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3608318567276001},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.26127755641937256},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.24257218837738037},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.19413167238235474},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.1867012083530426},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000099193","descriptor_name":"rab11 GTP-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007685","descriptor_name":"Kidney Tubules, Collecting","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007685","descriptor_name":"Kidney Tubules, Collecting","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011992","descriptor_name":"Endosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020691","descriptor_name":"rab GTP-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053503","descriptor_name":"Epithelial Sodium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1152/ajprenal.00304.2011","doi":"https://doi.org/10.1152/ajprenal.00304.2011","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajprenal.00304.2011","pdf_url":null,"source":{"id":"https://openalex.org/S200780590","display_name":"American Journal of Physiology-Renal Physiology","issn_l":"1522-1466","issn":["1522-1466","1931-857X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Renal Physiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2583328","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3353647","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3353647","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3353647","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Physiol Renal Physiol","raw_type":"Text"},{"id":"pmid:22129970","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22129970","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Renal physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2583328","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3353647","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2497218721","display_name":"Endocytic and Exocytic Traffic in Bladder Uroepithelium","funder_award_id":"R37DK054425","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3368990301","display_name":"Trafficking and Regulation of the Epithelial Na+ Channel","funder_award_id":"R01DK057718","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G517453109","display_name":"Cellular Mechanisms of Action of Mineralocorticoid Hormones","funder_award_id":"R01DK047874","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6713502407","display_name":"Traffic Regulatory Proteins and ENaC","funder_award_id":"R01DK054814","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7582243716","display_name":"Pittsburgh Center for Kidney Research","funder_award_id":"P30DK079307","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8476216647","display_name":"Adenosine Receptor Function in Bladder Uroepithelium","funder_award_id":"R01DK077777","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8886680879","display_name":"EnaC regulation in the kidney by vesicle trafficking and recycling","funder_award_id":"K99DK078917","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W74393652","https://openalex.org/W1567839284","https://openalex.org/W1599782720","https://openalex.org/W1818300518","https://openalex.org/W1961777300","https://openalex.org/W1965762453","https://openalex.org/W1967581940","https://openalex.org/W1977303922","https://openalex.org/W1979112180","https://openalex.org/W1982363657","https://openalex.org/W1989287806","https://openalex.org/W1995270157","https://openalex.org/W1997669162","https://openalex.org/W2001984495","https://openalex.org/W2004186506","https://openalex.org/W2005323790","https://openalex.org/W2012329129","https://openalex.org/W2012613986","https://openalex.org/W2012818550","https://openalex.org/W2013961817","https://openalex.org/W2022941489","https://openalex.org/W2027199606","https://openalex.org/W2032115986","https://openalex.org/W2034728504","https://openalex.org/W2038969638","https://openalex.org/W2043134189","https://openalex.org/W2050203730","https://openalex.org/W2051712209","https://openalex.org/W2055753274","https://openalex.org/W2064880862","https://openalex.org/W2065844414","https://openalex.org/W2066972887","https://openalex.org/W2067560720","https://openalex.org/W2069572560","https://openalex.org/W2071051861","https://openalex.org/W2071103368","https://openalex.org/W2075083639","https://openalex.org/W2079127109","https://openalex.org/W2082387821","https://openalex.org/W2083291077","https://openalex.org/W2092920907","https://openalex.org/W2094984821","https://openalex.org/W2099071036","https://openalex.org/W2104608782","https://openalex.org/W2106064900","https://openalex.org/W2106227617","https://openalex.org/W2107827966","https://openalex.org/W2112751496","https://openalex.org/W2115373693","https://openalex.org/W2117377105","https://openalex.org/W2120245762","https://openalex.org/W2124385473","https://openalex.org/W2126660909","https://openalex.org/W2127326086","https://openalex.org/W2129172715","https://openalex.org/W2131794840","https://openalex.org/W2131844352","https://openalex.org/W2136901254","https://openalex.org/W2151502323","https://openalex.org/W2156383636","https://openalex.org/W2161647218","https://openalex.org/W2165603439","https://openalex.org/W2166341843","https://openalex.org/W2167221791","https://openalex.org/W2171624087","https://openalex.org/W2172109574","https://openalex.org/W2320009463","https://openalex.org/W2335058519","https://openalex.org/W2409121238","https://openalex.org/W2409564119","https://openalex.org/W2414325302"],"related_works":["https://openalex.org/W14009848","https://openalex.org/W2038969638","https://openalex.org/W3166991887","https://openalex.org/W2075083639","https://openalex.org/W2022722621","https://openalex.org/W2029309701","https://openalex.org/W3173823235","https://openalex.org/W2032115986","https://openalex.org/W2094984821","https://openalex.org/W2144558863"],"abstract_inverted_index":{"Expression":[0,84],"of":[1,11,85,91,116,123],"the":[2,8,47,68,97,114,128,151],"epithelial":[3],"sodium":[4,102],"channel":[5,69],"(ENaC)":[6],"at":[7],"apical":[9],"membrane":[10,39],"cortical":[12],"collecting":[13],"duct":[14],"(CCD)":[15],"principal":[16],"cells":[17],"is":[18,44,147],"modulated":[19],"by":[20,24,78],"regulated":[21],"trafficking":[22],"mediated":[23],"vesicle":[25,35],"insertion":[26],"and":[27,38,75,80,99,141,153],"retrieval.":[28],"Small":[29],"GTPases":[30],"are":[31],"known":[32,45],"to":[33,72,142],"facilitate":[34],"trafficking,":[36],"recycling,":[37],"fusion":[40],"events;":[41],"however,":[42],"little":[43],"about":[46],"specific":[48],"Rab":[49],"family":[50],"members":[51],"that":[52,63,139],"modify":[53],"ENaC":[54,66,133],"surface":[55,134],"density.":[56],"Using":[57],"a":[58,86,143],"mouse":[59],"CCD":[60],"cell":[61],"line":[62],"endogenously":[64],"expresses":[65],"(mpkCCD),":[67],"was":[70,111],"localized":[71],"both":[73],"Rab11a-":[74],"Rab11b-positive":[76],"endosomes":[77],"immunoisolation":[79],"confocal":[81],"fluorescent":[82],"microscopy.":[83],"dominant":[87],"negative":[88],"(DN)":[89],"form":[90],"Rab11a":[92],"or":[93],"Rab11b":[94,131],"significantly":[95],"reduced":[96],"basal":[98],"cAMP-stimulated":[100,154],"ENaC-dependent":[101],"(Na(+))":[103],"transport.":[104],"The":[105],"greatest":[106],"reduction":[107],"in":[108,132,149,157],"Na(+)":[109,155],"transport":[110,156],"observed":[112],"with":[113],"expression":[115],"DN-Rab11b.":[117],"Furthermore,":[118],"small":[119],"interfering":[120],"RNA-mediated":[121],"knockdown":[122],"each":[124],"Rab11":[125],"isoform":[126],"demonstrated":[127],"requirement":[129],"for":[130],"expression.":[135],"These":[136],"data":[137],"indicate":[138],"Rab11b,":[140],"lesser":[144],"extent":[145],"Rab11a,":[146],"involved":[148],"establishing":[150],"constitutive":[152],"mpkCCD":[158],"cells.":[159]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}