{"id":"https://openalex.org/W2109953719","doi":"https://doi.org/10.1016/j.jamcollsurg.2010.06.196","title":"Alterations in small intestinal mucosa of mice lacking the serotonin reuptake transporter are 5HT2A receptor-dependent","display_name":"Alterations in small intestinal mucosa of mice lacking the serotonin reuptake transporter are 5HT2A receptor-dependent","publication_year":2010,"publication_date":"2010-08-31","ids":{"openalex":"https://openalex.org/W2109953719","doi":"https://doi.org/10.1016/j.jamcollsurg.2010.06.196","mag":"2109953719"},"language":"en","primary_location":{"id":"doi:10.1016/j.jamcollsurg.2010.06.196","doi":"https://doi.org/10.1016/j.jamcollsurg.2010.06.196","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2010.06.196","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111525364","display_name":"Erica Rachel Gross","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294429298","display_name":"Morgan Stanley Children's Hospital","ror":"https://ror.org/016m8pd54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294429298","https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erica Rachel Gross","raw_affiliation_strings":["Morgan Stanley Children's Hospital/Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Morgan Stanley Children's Hospital/Columbia University, New York, NY","institution_ids":["https://openalex.org/I1294429298","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002432406","display_name":"Ross Mazo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294429298","display_name":"Morgan Stanley Children's Hospital","ror":"https://ror.org/016m8pd54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294429298","https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ross E. Mazo","raw_affiliation_strings":["Morgan Stanley Children's Hospital/Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Morgan Stanley Children's Hospital/Columbia University, New York, NY","institution_ids":["https://openalex.org/I1294429298","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009666792","display_name":"Zoya V. Gertsberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294429298","display_name":"Morgan Stanley Children's Hospital","ror":"https://ror.org/016m8pd54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294429298","https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zoya V. Gertsberg","raw_affiliation_strings":["Morgan Stanley Children's Hospital/Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Morgan Stanley Children's Hospital/Columbia University, New York, NY","institution_ids":["https://openalex.org/I1294429298","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019329770","display_name":"Michael David Gershon","orcid":"https://orcid.org/0000-0002-5893-7643","observed_orcids":["https://orcid.org/0000-0002-5893-7643"]},"institutions":[{"id":"https://openalex.org/I1294429298","display_name":"Morgan Stanley Children's Hospital","ror":"https://ror.org/016m8pd54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294429298","https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael D. Gershon","raw_affiliation_strings":["Morgan Stanley Children's Hospital/Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Morgan Stanley Children's Hospital/Columbia University, New York, NY","institution_ids":["https://openalex.org/I1294429298","https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065891946","display_name":"Robert A. Cowles","orcid":"https://orcid.org/0000-0002-3375-9158","observed_orcids":["https://orcid.org/0000-0002-3375-9158"]},"institutions":[{"id":"https://openalex.org/I1294429298","display_name":"Morgan Stanley Children's Hospital","ror":"https://ror.org/016m8pd54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294429298","https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Cowles","raw_affiliation_strings":["Morgan Stanley Children's Hospital/Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Morgan Stanley Children's Hospital/Columbia University, New York, NY","institution_ids":["https://openalex.org/I1294429298","https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20029959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"211","issue":"3","first_page":"S75","last_page":"S75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.8910999894142151,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.8910999894142151,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.05310000106692314,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.011500000022351742,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonin-transporter","display_name":"serotonin transporter","score":0.8420000076293945},{"id":"https://openalex.org/keywords/sert-knockout-mice","display_name":"SERT knockout mice","score":0.8349999785423279},{"id":"https://openalex.org/keywords/small-intestinal-mucosa","display_name":"small intestinal mucosa","score":0.8119999766349792},{"id":"https://openalex.org/keywords/5-ht2a-receptor","display_name":"5-HT2A receptor","score":0.9589999914169312},{"id":"https://openalex.org/keywords/serotonin-signaling","display_name":"serotonin signaling","score":0.5860000252723694},{"id":"https://openalex.org/keywords/intestinal-epithelium","display_name":"intestinal epithelium","score":0.6570000052452087},{"id":"https://openalex.org/keywords/enteric-nervous-system","display_name":"enteric nervous system","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C2778897192","wikidata":"https://www.wikidata.org/wiki/Q410142","display_name":"Serotonin transporter","level":4,"score":0.8033975958824158},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7383151054382324},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.7017248272895813},{"id":"https://openalex.org/C126855140","wikidata":"https://www.wikidata.org/wiki/Q14891424","display_name":"5-HT2A receptor","level":5,"score":0.5808678269386292},{"id":"https://openalex.org/C99631742","wikidata":"https://www.wikidata.org/wiki/Q22290476","display_name":"Reuptake","level":4,"score":0.5344694256782532},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.5210009217262268},{"id":"https://openalex.org/C53910766","wikidata":"https://www.wikidata.org/wiki/Q238516","display_name":"5-HT receptor","level":4,"score":0.517370879650116},{"id":"https://openalex.org/C2908747647","wikidata":"https://www.wikidata.org/wiki/Q238516","display_name":"Serotonin Plasma Membrane Transport Proteins","level":5,"score":0.4231835603713989},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.422513484954834},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4070603847503662},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3742954134941101},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09679245948791504},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08807522058486938},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06182360649108887}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jamcollsurg.2010.06.196","doi":"https://doi.org/10.1016/j.jamcollsurg.2010.06.196","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2010.06.196","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2059631609","https://openalex.org/W2053908167","https://openalex.org/W2097785193","https://openalex.org/W2984312502","https://openalex.org/W2066285585","https://openalex.org/W2170724754","https://openalex.org/W2339303564","https://openalex.org/W1590246719","https://openalex.org/W4378674543","https://openalex.org/W8532061"],"abstract_inverted_index":{"Gross,":[0],"Erica":[1],"Rachel":[2],"MD;":[3,15],"Mazo,":[4],"Ross":[5],"E.":[6],"BA;":[7],"Gertsberg,":[8],"Zoya":[9],"V.":[10],"MS;":[11],"Gershon,":[12],"Michael":[13],"D.":[14],"Cowles,":[16],"Robert":[17],"A.":[18],"MD":[19],"Author":[20],"Information":[21]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}